KarthikNathanMD

PubMed

• 3 citations
  Do-Not-Resuscitate status is an independent risk factor for medical complications and mortality among geriatric patients sustaining hip fractures
  Liam C. Bosch, Karthik Nathan, Laura Lu, Sean T. Campbell, Michael J. Gardner, Julius A. Bishop> ;Journal of Clinical Orthopaedics and Trauma. 2021 Mar 1
• 1 citations
  Deciding without data: clinical decision-making in pediatric orthopedic surgery.
  Karthik Nathan, Maechi Uzosike, Uriel Sanchez, Alexander Karius, Jacinta Leyden, Nicole A. Segovia, Sara L. Eppler, Katherine G. Hastings, Robin N. Kamal, Steven L. Frick> ;International Journal for Quality in Health Care. 2020 Dec 15
• 1 citations
  Increased NF-κB Activity in Osteoprogenitor-Lineage Cells Impairs the Balance of Bone Versus Fat in the Marrow of Skeletally Mature Mice
  Tzuhua Lin, Jukka Pajarinen, Yusuke Kohno, Akira Nabeshima, Laura Lu, Karthik Nathan, Zhenyu Yao, Joy Y. Wu, Stuart B. Goodman> ;Regenerative Engineering and Translational Medicine. 2020 Mar 1
• 8 citations
  Effect of Aging on the Macrophage Response to Titanium Particles.
  Eemeli Jämsen, Jukka Pajarinen, Tzuhua Lin, Chi-Wen Lo, Akira Nabeshima, Laura Lu, Karthik Nathan, Kari K. Eklund, Zhenyu Yao, Stuart B. Goodman> ;Journal of Orthopaedic Research. 2020 Feb 1
• 42 citations
  Precise immunomodulation of the M1 to M2 macrophage transition enhances mesenchymal stem cell osteogenesis and differs by sex
  Karthik Nathan, Laura Lu, Tzuhua Lin, Jukka Pajarinen, Eemeli Jämsen, Jhih-Fong Huang, Monica Romero-Lopez, Masahiro Maruyama, Yusuke Kohno, Zhenyu Yao, Stuart B. Goodman> ;Bone & Joint Research. 2019 Oct 21
• 25 citations
  Preconditioned or IL4-Secreting Mesenchymal Stem Cells Enhanced Osteogenesis at Different Stages.
  Tzuhua Lin, Yusuke Kohno, Jhih-Fong Huang, Monica Romero-Lopez, Masahiro Maruyama, Masaya Ueno, Jukka Pajarinen, Karthik Nathan, Zhenyu Yao, Fan Yang, Joy Y. Wu, Stuar...> ;Tissue Engineering. Part A. 2019 Aug 5
• 13 citations
  Decreased estimated blood loss in lateral trans-psoas versus anterior approach to lumbar interbody fusion for degenerative spondylolisthesis
  L. Henry Goodnough, Jayme C.B. Koltsov, Tianyi Wang, Grace Xiong, Karthik Nathan, Ivan Cheng> ;Journal of Spine Surgery. 2019 Jun 1
• 6 citations
  Treating Titanium Particle-Induced Inflammation with Genetically Modified NF-κB Sensing IL-4 Secreting or Preconditioned Mesenchymal Stem Cells in Vitro.
  Yusuke Kohno, Tzuhua Lin, Jukka Pajarinen, Eemeli Jämsen, Monica Romero-Lopez, Masahiro Maruyama, Chi-Wen Lo, Masaya Ueno, Karthik Nathan, Zhenyu Yao, Stuart B. Goodman> ;ACS Biomaterials Science & Engineering. 2019 May 1
• 19 citations
  Trained murine mesenchymal stem cells have anti-inflammatory effect on macrophages, but defective regulation on T-cell proliferation
  Tzuhua Lin, Jukka Pajarinen, Yusuke Kohno, Jhih-Fong Huang, Masahiro Maruyama, Monica Romero-Lopez, Karthik Nathan, Zhenyu Yao, Stuart B. Goodman> ;FASEB Journal. 2019 Mar 1
• 4 citations
  Osteogenic ability of rat bone marrow concentrate is at least as efficacious as mesenchymal stem cells in vitro.
  Yusuke Kohno, Tzuhua Lin, Jukka Pajarinen, Monica Romero-Lopez, Masahiro Maruyama, Jhih-Fong Huang, Karthik Nathan, Zhenyu Yao, Stuart B. Goodman> ;Journal of Biomedical Materials Research. Part B, Applied Biomaterials. 2019 Feb 19
• 32 citations
  NFκB sensing IL-4 secreting mesenchymal stem cells mitigate the proinflammatory response of macrophages exposed to polyethylene wear particles.
  Tzuhua Lin, Yusuke Kohno, Jhih-Fong Huang, Monica Romero-Lopez, Jukka Pajarinen, Masahiro Maruyama, Karthik Nathan, Zhenyu Yao, Stuart B. Goodman> ;Journal of Biomedical Materials Research. Part A. 2018 Aug 7
• 18 citations
  Transplanted interleukin-4--secreting mesenchymal stromal cells show extended survival and increased bone mineral density in the murine femur.
  Tzuhua Lin, Jukka Pajarinen, Yusuke Kohno, Masahiro Maruyama, Monica Romero-Lopez, Jhih-Fong Huang, Karthik Nathan, Tahsin N. Khan, Zhenyu Yao, Stuart B. Goodman> ;Cytotherapy. 2018 Aug 1
• 424 citations
  Mesenchymal stem cell-macrophage crosstalk and bone healing
  Jukka Pajarinen, Tzuhua Lin, Emmanuel Gibon, Yusuke Kohno, Masahiro Maruyama, Karthik Nathan, Laura Lu, Zhenyu Yao, Stuart B. Goodman> ;Biomaterials. 2018 Jan 2
• 82 citations
  Preconditioning of murine mesenchymal stem cells synergistically enhanced immunomodulation and osteogenesis.
  Tzuhua Lin, Jukka Pajarinen, Akira Nabeshima, Laura Lu, Karthik Nathan, Eemeli Jämsen, Zhenyu Yao, Stuart B. Goodman> ;Stem Cell Research & Therapy. 2017 Dec 6
• 18 citations
  Murine Model of Progressive Orthopedic Wear Particle-Induced Chronic Inflammation and Osteolysis
  Jukka Pajarinen, Akira Nabeshima, Tzuhua Lin, Taishi Sato, Emmanuel Gibon, Eemeli Jämsen, Laura Lu, Karthik Nathan, Zhenyu Yao, Stuart B. Goodman> ;Tissue Engineering. Part C, Methods. 2017 Dec 1
• 118 citations
  Pro-inflammatory M1 macrophages promote Osteogenesis by mesenchymal stem cells via the COX-2-prostaglandin E2 pathway.
  Laura Lu, Florence Loi, Karthik Nathan, Tzuhua Lin, Jukka Pajarinen, Emmanuel Gibon, Akira Nabeshima, Luis A. Córdova, Eemeli Jämsen, Zhenyu Yao, Stuart B. Goodman> ;Journal of Orthopaedic Research. 2017 Nov 1
• 11 citations
  Orthopaedic wear particle-induced bone loss and exogenous macrophage infiltration is mitigated by local infusion of NF-κB decoy oligodeoxynucleotide
  Tzuhua Lin, Jukka Pajarinen, Akira Nabeshima, Luis A. Córdova, Florence Loi, Emmanuel Gibon, Laura Lu, Karthik Nathan, Eemeli Jämsen, Zhenyu Yao, Stuart B. Goodman> ;Journal of Biomedical Materials Research. Part A. 2017 Sep 13
• 40 citations
  Establishment of NF-κB sensing and interleukin-4 secreting mesenchymal stromal cells as an “on-demand” drug delivery system to modulate inflammation
  Tzuhua Lin, Jukka Pajarinen, Akira Nabeshima, Laura Lu, Karthik Nathan, Zhenyu Yao, Stuart B. Goodman> ;Cytotherapy. 2017 Sep 1
• 75 citations
  Inflammation, ageing, and bone regeneration.
  Emmanuel Gibon, Laura Lu, Karthik Nathan, Stuart B. Goodman> ;Journal of Orthopaedic Translation. 2017 Jul 1
• 33 citations
  Mesenchymal stem cells in the aseptic loosening of total joint replacements.
  Jukka Pajarinen, Tzuhua Lin, Akira Nabeshima, Eemeli Jämsen, Laura Lu, Karthik Nathan, Zhenyu Yao, Stuart B. Goodman> ;Journal of Biomedical Materials Research. Part A. 2017 Feb 1
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