KatherineEmbryBungeMD

Obstetrics & Gynecology • Bethel Park, PA

Assistant Professor, Ob/Gyn & Reproductive Science, University of Pittsburgh School of Medicine

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Office
1300 Oxford Drive
Ste 1100
Bethel Park, PA 15102
Phone+1 412-641-8851

Fax+1 412-641-8858
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Education & Training

McGaw Medical Center of Northwestern UniversityResidency, Obstetrics and Gynecology, 2002 - 2006
Johns Hopkins University School of MedicineClass of 2002

Certifications & Licensure

PA State Medical License 2006 - 2024
IL State Medical License 2002 - 2008
American Board of Obstetrics and Gynecology Obstetrics & Gynecology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2011
Fellow (FACOG) American Congress of Obstetricians and Gynecologists
Most Compassionate Doctor American Registry

Clinical Trials

Chlamydia Trachomatis Immunology and Vaccinology Study Start of enrollment: 2011 Jan 01
Completed
Optimization of the ex Vivo Challenge Start of enrollment: 2014 May 01
Completed
Contraceptive/HIV Affecting Risk in Adolescents Start of enrollment: 2017 Jul 31
Terminated
A Study of the Safety and Acceptability of a Placebo Vaginal Film: FAME101 Start of enrollment: 2018 May 22
Completed
Not Applicable
Randomized, Open Label Safety Trial of Dapivirine Vaginal Ring and Oral TRUVADA® Use in Pregnancy Start of enrollment: 2020 Jan 09
Active, not recruiting
Phase 3
Safety and Pharmacokinetics of Two Vaginal Film Formulations Containing the Integrase Inhibitor MK-2048 Start of enrollment: 2020 Aug 19
Completed
Phase 1
Randomized Cross-Over Study of Self-Insertion of Two Placebo Vaginal Film Formulations Start of enrollment: 2020 Jul 14
Completed
Not Applicable
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Publications & Presentations

PubMed

Phase 1 randomized pharmacokinetic and safety study of a 90-day tenofovir vaginal ring in the United States.
Albert Y Liu, Holly Gundacker, Barbra Richardson, Beatrice A Chen, Craig Hoesley, Ariane van der Straten, Amanda Brown, May Beamer, Jennifer Robinson, Cindy E Jacobson...> ;Journal of the International AIDS Society. 2024 Mar 1
Maternal COVID-19 Vaccination and Prevention of Symptomatic Infection in Infants.
Cardemil, C., Cao, Y., Posavad, C., Badell, M., Bunge, K., Mulligan, M., Parameswaran, L., Olson-Chen, C., Novak, R., Brady, R., DeFranco, E., Gerber, J., Pasetti, M.,...> ;Pediatrics. 2024 Mar 1
1 citations
DELIVER: A Safety Study of a Dapivirine Vaginal Ring and Oral PrEP for the Prevention of HIV During Pregnancy.
Bunge, K., Balkus, J., Fairlie, L., Mayo, A., Nakabiito, C., Mgodi, N., Gadama, L., Matrimbira, M., Chappell, C., Piper, J., Chakhtoura, N., Szydlo, D., Richardson, B....> ;Journal of Acquired Immune Deficiency Syndromes. 2024 Jan 1
DELIVER: A Safety Study of a Dapivirine Vaginal Ring and Oral PrEP for the Prevention of HIV During Pregnancy.
Katherine Bunge, Jennifer E Balkus, Lee Fairlie, Ashley J Mayo, Clemensia Nakabiito, Nyaradzo Mgodi, Luis Gadama, Moleen Matrimbira, Catherine Anne Chappell, Jeanna Pi...> ;Journal of Acquired Immune Deficiency Syndromes. 2023 Sep 27
11 citations
COVID-19 booster vaccination during pregnancy enhances maternal binding and neutralizing antibody responses and transplacental antibody transfer to the newborn.
Flor M Munoz, Christine M Posavad, Barbra A Richardson, Martina L Badell, Katherine E Bunge, Mark J Mulligan, Lalitha Parameswaran, Clifton W Kelly, Courtney Olson-Che...> ;Vaccine. 2023 Aug 14
1 citations
Implementing pre-exposure prophylaxis for HIV prevention in women: the role of the obstetrician-gynecologist.
Sharlay K Butler, Yasaswi Kislovskiy, Katherine Bunge, Harold C Wiesenfeld> ;American Journal of Obstetrics and Gynecology. 2022 Jun 1
4 citations
Pooled Prevalence of Adverse Pregnancy and Neonatal Outcomes in Malawi, South Africa, Uganda, and Zimbabwe: Results From a Systematic Review and Meta-Analyses to Infor...
Erica M Lokken, Anya Mathur, Katherine E. Bunge, Lee Fairlie, Bonus Makanani, Richard H. Beigi, Lisa M. Noguchi, Jennifer E. Balkus> ;Frontiers in Reproductive Health. 2021 Nov 26
12 citations
Phase 1 pharmacokinetics and safety study of extended duration dapivirine vaginal rings in the United States.
Albert Y. Liu, Clara P Dominguez Islas, Holly Gundacker, Blazej Neradilek, Craig J. Hoesley, Ariane van der Straten, Craig W. Hendrix, M.A. Beamer, Cindy Jacobson, Tar...> ;Journal of the International AIDS Society. 2021 Jun 1
Experiences with simultaneous use of contraception and the vaginal ring for HIV prevention in sub-Saharan Africa.
Jonah Leslie, Flavia Matovu Kiweewa, Thesla Palanee-Phillips, Katherine E. Bunge, Felix Mhlanga, Betty Kamira, Jared M. Baeten, Ariana W K Katz, Sharon L. Hillier, Eli...> ;BMC Women's Health. 2021 Apr 23
10 citations
Assessing pregnancy and neonatal outcomes in Malawi, South Africa, Uganda, and Zimbabwe: Results from a systematic chart review.
Jennifer E. Balkus, Moni B. Neradilek, Lee Fairlie, Bonus Makanani, Nyaradzo Mgodi, Felix Mhlanga, Clemensia Nakabiito, Ashley J Mayo, Tanya M. Harrell, Jeanna M. Pipe...> ;Plos One. 2021 Mar 31
1 citations
A qualitative study on the acceptability of and adherence to a vaginal ring for HIV prophylaxis among adolescent girls
Zoë Baker, Marjan Javanbacht, Janell Moore, Hannah Brosnan, Kathleen Squires, Katherine E. Bunge, Gregory D. Zimet, Barbara S. Mensch, Lydia Soto-Torres, Bill G. Kapog...> ;Journal of Acquired Immune Deficiency Syndromes. 2021 Mar 1
3 citations
Influence of dapivirine vaginal ring use on cervicovaginal immunity and functional microbiome in adolescent girls.
Christina Farr Zuend, Laura Noël-Romas, Sarah Hoger, Stuart McCorriser, Garrett Westmacott, Jeanne M. Marrazzo, Sharon L. Hillier, Charlene S. Dezzutti, Kathleen Squir...> ;AIDS. 2021 Mar 1
58 citations
Safety, uptake, and use of a dapivirine vaginal ring for HIV-1 prevention in African women (HOPE): An open-label, extension study
Jared M. Baeten, Thesla Palanee-Phillips, Nyaradzo Mgodi, Ashley J Mayo, Daniel W. Szydlo, Gita Ramjee, Brenda Gati Mirembe, Felix Mhlanga, Portia Hunidzarira, Leila E...> ;The Lancet. HIV. 2021 Feb 1
55 citations
Ledipasvir plus sofosbuvir in pregnant women with hepatitis C virus infection: a phase 1 pharmacokinetic study
Catherine A. Chappell, Kimberly K. Scarsi, Brian J. Kirby, Vithika Suri, Anuj Gaggar, Debra L. Bogen, Ingrid Macio, Leslie A. Meyn, Katherine E. Bunge, Elizabeth E. Kr...> ;The Lancet. Microbe. 2020 Sep 1
18 citations
Elevated Risk of Bacterial Vaginosis Among Users of the Copper Intrauterine Device: A Prospective Longitudinal Cohort Study.
Kathryn Peebles, Flavia Matovu Kiweewa, Thesla Palanee-Phillips, Catherine A. Chappell, Devika Singh, Katherine E. Bunge, Logashvari Naidoo, Bonus Makanani, Nitesha Je...> ;Clinical Infectious Diseases. 2021 Aug 2
3 citations
Use of the dapivirine vaginal ring and effect on cervical cytology abnormalities.
Krishnaveni Reddy, Cliff Kelly, Elizabeth R. Brown, Nitesha Jeenarain, Logashvari Naidoo, Samantha Siva, Linda-Gail Bekker, Gonasagrie Nair, Bonus Makanani, Lameck Chi...> ;AIDS. 2020 Mar 15
16 citations
Brief Report: Phase IIa Safety Study of a Vaginal Ring Containing Dapivirine in Adolescent Young Women.
Katherine E. Bunge, Lisa Levy, Daniel W. Szydlo, Jingyang Zhang, Aditya H. Gaur, Daniel Reirden, Kenneth H. Mayer, Donna Futterman, Craig J. Hoesley, Sharon L. Hillier...> ;Journal of Acquired Immune Deficiency Syndromes. 2020 Feb 1
10 citations
Social harms in female-initiated HIV prevention method research: state of the evidence.
Elizabeth T. Montgomery, Sarah T. Roberts, Annalene Nel, Mariëtte Malherbe, Kristine Torjesen, Katherine E. Bunge, Devika Singh, Jared M. Baeten, Jeanne M. Marrazzo, Z...> ;AIDS. 2019 Nov 15
7 citations
Contraceptive method switching among women living in sub-Saharan Africa participating in an HIV-1 prevention trial: a prospective cohort study
Catherine A. Chappell, Ishana Harkoo, Daniel W. Szydlo, Katherine E. Bunge, Clemensia Nakabiito, Felix Mhlanga, Betty Kamira, Jeanna M. Piper, Jennifer E. Balkus, Shar...> ;Contraception. 2019 Sep 1
14 citations
Pharmacokinetics of Dapivirine Transfer into Blood Plasma, Breast Milk, and Cervicovaginal Fluid of Lactating Women Using the Dapivirine Vaginal Ring
Lisa M. Noguchi, Craig J. Hoesley, Cliff Kelly, Rachel Scheckter, Katherine E. Bunge, Annalene Nel, Mark A. Marzinke, Craig W. Hendrix, Charlene S. Dezzutti, Sharon L....> ;Antimicrobial Agents and Chemotherapy. 2019 Feb 26
11 citations
Vaginal Product Formulation Alters the Innate Antiviral Activity and Glycome of Cervicovaginal Fluids with Implications for Viral Susceptibility
Sujeethraj Koppolu, Linlin Wang, Ayushi Mathur, Jayeshwar A. Nigam, Charlene S. Dezzutti, Charles E. Isaacs, Leslie A. Meyn, Katherine E. Bunge, Bernard J. Moncla, Sha...> ;ACS Infectious Diseases. 2018 Sep 5
26 citations
FAME-04: A Phase 1 trial to assess the safety, acceptability, pharmacokinetics and pharmacodynamics of film and gel formulations of tenofovir.
Katherine E. Bunge, Charlene S. Dezzutti, Craig W. Hendrix, Mark A. Marzinke, Hans M. L. Spiegel, Bernard J. Moncla, Jill L. Schwartz, Leslie A. Meyn, Nicola Richardso...> ;Journal of the International AIDS Society. 2018 Aug 1
3 citations
Heterogeneity of HIV-1 Replication in Ectocervical and Vaginal Tissue Ex Vivo.
Charlene S. Dezzutti, Seo Young Park, Kenneth M Marks, Sidney E Lawlor, Julie Russo, Ingrid Macio, Catherine A. Chappell, Katherine E. Bunge> ;AIDS Research and Human Retroviruses. 2017 Dec 14
6 citations
Contraceptive Use and Pregnancy Incidence Among Women Participating in an HIV Prevention Trial.
Carolyne Akello, Katherine E. Bunge, Clemensia Nakabiito, Brenda Gati Mirembe, Mary Glenn Fowler, Anupam Mishra, Jeanne M. Marrazzo, Zvavahera M. Chirenje, Connie Celu...> ;Journal of Women's Health. 2017 Jun 1
29 citations
Bacterial species colonizing the vagina of healthy women are not associated with race.
M.A. Beamer, Michele N. Austin, H.A. Avolia, Leslie A. Meyn, Katherine E. Bunge, Sharon L. Hillier> ;Anaerobe. 2017 Jun 1
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Press Mentions

NIH-Funded Clinical Trial to Test PrEP, Dapivirine Ring for Safety in Pregnant WomenFebruary 10th, 2020
Making Clinical Trials of PrEP More Inclusive of Women, No Matter Their Pregnancy StatusSeptember 25th, 2018
HIV Prevention Dapivirine Vaginal Ring Found Safe and Acceptable in US Adolescent GirlsJuly 25th, 2017