KatherineFitzgeraldDO

PubMed

• 101 citations
  Apoptosis, Pyroptosis, and Necroptosis-Oh My! The Many Ways a Cell Can Die.
  Natália Ketelut-Carneiro, Katherine A. Fitzgerald> ;Journal of Molecular Biology. 2021 Nov 25
• 9 citations
  A genetic screen in macrophages identifies new regulators of IFNγ-inducible MHCII that contribute to T cell activation.
  Michael C. Kiritsy, Laurisa M Ankley, Justin Trombley, Gabrielle P Huizinga, Audrey E Lord, Pontus Orning, Roland Elling, Katherine A. Fitzgerald, Andrew J. Olive> ;Elife. 2021 Nov 8
• 4 citations
  From mRNA sensing to vaccines.
  Anthony S. Fauci, Miriam Merad, Soumya Swaminathan, Sun Hur, Eric Topol, Katherine A. Fitzgerald, Caetano Reis e Sousa, Kizzmekia S. Corbett, Stefan Bauer> ;Immunity. 2021 Oct 28
• 8 citations
  UMP-CMP kinase 2 gene expression in macrophages is dependent on the IRF3-IFNAR signaling axis.
  Hera Kim, Yashwanth Subbannayya, Fiachra Humphries, Astrid Skejsol, Sneha M. Pinto, Miriam Giambelluca, Terje Espevik, Katherine A. Fitzgerald, Richard Kumaran Kandasamy> ;Plos One. 2021 Oct 27
• 31 citations
  AIM2 regulates anti-tumor immunity and is a viable therapeutic target for melanoma.
  Keitaro Fukuda, Ken Okamura, Rebecca L. Riding, Xueli Fan, Khashayar Afshari, Nazgol-Sadat Haddadi, Sean M. McCauley, Mehmet Hakan Guney, Jeremy Luban, Takeru Funakosh...> ;The Journal of Experimental Medicine. 2021 Sep 6
• Igniting the firestorm: The inflammasome in autoinflammatory syndromes.
  Fiachra Humphries, Katherine A. Fitzgerald> ;The Journal of Allergy and Clinical Immunology. 2021 Aug 13
• 13 citations
  Cellular nucleic acid–binding protein is essential for type I interferon–mediated immunity to RNA virus infection
  Yongzhi Chen, Xuqiu Lei, Zhaozhao Jiang, Katherine A. Fitzgerald> ;Proceedings of the National Academy of Sciences of the United States of America. 2021 Jun 29
• 43 citations
  Dysbiosis exacerbates colitis by promoting ubiquitination and accumulation of the innate immune adaptor STING in myeloid cells
  Liraz Shmuel-Galia, Fiachra Humphries, Xuqiu Lei, Simona Ceglia, Ruth Wilson, Zhaozhao Jiang, Natália Ketelut-Carneiro, Sage E. Foley, Susanne Pechhold, JeanMarie Houg...> ;Immunity. 2021 Jun 8
• 80 citations
  A diamidobenzimidazole STING agonist protects against SARS-CoV-2 infection
  Fiachra Humphries, Liraz Shmuel-Galia, Zhaozhao Jiang, Ruth Wilson, Philip S. Landis, Sze-Ling Ng, Krishna-Mohan Parsi, René Maehr, John Cruz, Angel I. Morales-Ramos, ...> ;Science Immunology. 2021 May 18
• 22 citations
  cGAS-STING Pathway Does Not Promote Autoimmunity in Murine Models of SLE
  Mona Motwani, Jason D. McGowan, Jennifer Antonovitch, Kevin MingJie Gao, Zhaozhao Jiang, Shrutie Sharma, Gretchen A. Baltus, Kevin M. Nickerson, Ann Marshak-Rothstein,...> ;Frontiers in Immunology. 2021 Mar 29
• 22 citations
  Lung Epithelial Cell Transcriptional Regulation as a Factor in COVID-19 Associated Coagulopathies.
  Ethan S. FitzGerald, Yongzhi Chen, Katherine A. Fitzgerald, Amanda M. Jamieson> ;American Journal of Respiratory Cell and Molecular Biology. 2021 Jun 4
• 21 citations
  Long non-coding RNAs in antiviral immunity
  Tim Vierbuchen, Katherine A. Fitzgerald> ;Seminars in Cell & Developmental Biology. 2021 Mar 1
• 56 citations
  Overcoming innate immune barriers that impede AAV gene therapy vectors.
  Manish Muhuri, Yukiko Maeda, Hong Ma, Sanjay Ram, Katherine A. Fitzgerald, Phillip W. L. Tai, Guangping Gao> ;The Journal of Clinical Investigation. 2021 Jan 12
• 44 citations
  The long non-coding RNA LUCAT1 is a negative feedback regulator of interferon responses in humans.
  Shiuli Agarwal, Tim Vierbuchen, Sreya Ghosh, Jennie Chan, Zhaozhao Jiang, Richard Kumaran Kandasamy, Emiliano P. Ricci, Katherine A. Fitzgerald> ;Nature Communications. 2020 Dec 11
• 14 citations
  Ensuring vaccine safety.
  David M. Knipe, Ofer Levy, Katherine A. Fitzgerald, Elke Mühlberger> ;Science. 2020 Dec 11
• 1 citations
  Loosening the grip on nuclear cGAS.
  Fiachra Humphries, Katherine A. Fitzgerald> ;Nature Genetics. 2020 Nov 23
• 1 citations
  Author Correction: Caspase-8 mediates inflammation and disease in rodent malaria.
  Larissa M. N. Pereira, Patricia A. Assis, Natalia M. de Araujo, Danielle Fernandes Durso, Caroline Junqueira, Marco Antonio Ataide, Dhelio Batista Pereira, Egil Lien, ...> ;Nature Communications. 2020 Nov 3
• 20 citations
  The genetic diversity of multiple sclerosis risk among Hispanic and African American populations living in the United States.
  Ashley Beecham, Lilyana Amezcua, Angel Chinea, Clara P. Manrique, C. Rubi, Noriko Isobe, Brett T. Lund, Adam Santaniello, Gary W. Beecham, Esteban G. Burchard, Manuel ...> ;Multiple Sclerosis. 2020 Oct 1
• 180 citations
  HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation
  Venkat Giri Magupalli, Roberto Negro, Yuzi Tian, Arthur V. Hauenstein, Giuseppe Di Caprio, Wesley Skillern, Qiufang Deng, Pontus Orning, Hasan B. Alam, Zoltan Maliga, ...> ;Science. 2020 Sep 18
• 9 citations
  Caspase-8 mediates inflammation and disease in rodent malaria
  Larissa M. N. Pereira, Patricia A. Assis, Natalia M. de Araujo, Danielle Fernandes Durso, Caroline Junqueira, Marco Antonio Ataide, Dhelio Batista Pereira, Egil Lien, ...> ;Nature Communications. 2020 Sep 14
• 67 citations
  STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1β expression.
  Jesse J. Balic, Hassan Albargy, Kevin Luu, Francis J. Kirby, W. Samantha N. Jayasekara, Finbar Mansell, Daniel J. Garama, Dominic De Nardo, Nikola Baschuk, Cynthia Lou...> ;Nature Communications. 2020 Jul 30
• 911 citations
  Toll-like Receptors and the Control of Immunity.
  Katherine A. Fitzgerald, Jonathan C. Kagan> ;Cell. 2020 Mar 19
• 56 citations
  Direct Binding to NLRP3 Pyrin Domain as a Novel Strategy to Prevent NLRP3-Driven Inflammation and Gouty Arthritis.
  Gabsik Yang, Hye E. Lee, Su-Jin Moon, Kyung Min Ko, Jung H. Koh, Jin Kyung Seok, Jun-Ki Min, Tae-Hwe Heo, Han Chang Kang, Yong-Yeon Cho, Hye Suk Lee, Katherine A. Fitz...> ;Arthritis & Rheumatology. 2020 Mar 5
• 4 citations
  TLR2 Dimerization Blockade Allows Generation of Homeostatic Intestinal Macrophages under Acute Colitis Challenge.
  Mor Gross-Vered, Liraz Shmuel-Galia, Batya Zarmi, Fiachra Humphries, Christoph A. Thaiss, Tomer-Meir Salame, Eyal David, Louise Chappell-Maor, Katherine A. Fitzgerald,...> ;Journal of Immunology. 2020 Feb 1
• 19 citations
  Long Non-coding RNA LincRNA-EPS Inhibits Host Defense Against Listeria monocytogenes Infection.
  Federica Agliano, Katherine A. Fitzgerald, Anthony T. Vella, Vijay A. K. Rathinam, Andrei E. Medvedev> ;Frontiers in Cellular and Infection Microbiology. 2020 Jan 22
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Journal Articles

• Nitro-Fatty Acids Are Formed in Response to Virus Infection and Are Potent Inhibitors of STING Palmitoylation and Signaling  
  Katherine A Fitzgerald, Jonathan J Miner, Proceedings of the National Academy of Sciences