KeithKeithEngelMDFAAP

PubMed

• Assessment: symptomatic treatment for muscle cramps (an evidence-based review): report of the Therapeutics and Technology Assessment Subcommittee of the American Acade...
  Mahajan, S., Engel, W.K.> ;Neurology. 2010 Oct 12
• Impaired autophagy in sporadic inclusion-body myositis and in endoplasmic reticulum stress-provoked cultured human muscle fibers.
  Nogalska, A., D'Agostino, C., Terracciano, C., Engel, W.K., Askanas, V.> ;Am J Pathol. 2010 Sep
• Decreased SIRT1 deacetylase activity in sporadic inclusion-body myositis muscle fibers.
  Nogalska, A., D'Agostino, C., Engel, W.K., Davies, K.A., Askanas, V.> ;Neurobiol Aging. 2010-09-01
• Frameshift and novel mutations in FUS in familial amyotrophic lateral sclerosis and ALS/dementia.
  Yan, J., Deng, H., Siddique, N., Fecto, F., Chen, W., Yang, Y., Liu, E., Donkervoort, S., Zheng, J.G., Shi, Y., Ahmeti, K.B., Brooks, B., Engel, W.K., Siddique, T.> ;Neurology. 2010 Aug 31
• Intravenous immunoglobulin in relapsing-remitting multiple sclerosis: a dose-finding trial.
  Engel, W. K., Fazekas, F., Lublin, F. D., Li, D., Freedman, M. S., Hartung, H. P., Rieckmann, P., Soelberg Sørensen, P., Maas-Enriquez, M., Sommerauer, B., Hanna, K.> ;Neurology. 2009-09-29
• In inclusion-body myositis muscle fibers Parkinson-associated DJ-1 is increased and oxidized.
  Terracciano, C., Nogalska, A., Engel, W.K., Wojcik, S., Askanas, V.> ;Free Radic Biol Med. 2008 Sep 15
• Expression of Nogo-A in human muscle fibers is not specific for amyotrophic lateral sclerosis.
  Askanas, V., Wojcik, S., Engel, W.K.> ;Ann Neurol. 2007 Dec
• Inclusion-body myositis, a multifactorial muscle disease associated with aging: current concepts of pathogenesis.
  Askanas, V., Engel, W.K.> ;Curr Opin Rheumatol. 2007 Nov
• Endoplasmic reticulum stress induces myostatin precursor protein and NF-kappaB in cultured human muscle fibers: relevance to inclusion body myositis.
  Nogalska, A., Wojcik, S., Engel, W.K., McFerrin, J., Askanas, V.> ;Exp Neurol. 2007 Apr
• Inclusion-body myositis: clinical, diagnostic, and pathologic aspects.
  Engel, W.K., Askanas, V.> ;Neurology. 2006 Jan 24
• Inclusion-body myositis: a myodegenerative conformational disorder associated with Abeta, protein misfolding, and proteasome inhibition.
  Askanas, V., Engel, W.K.> ;Neurology. 2006 Jan 24
• Proteasome inhibition and aggresome formation in sporadic inclusion-body myositis and in amyloid-beta precursor protein-overexpressing cultured human muscle fibers.
  Fratta, P., Engel, W.K., McFerrin, J., Davies, K.A., Lin, S.W., Askanas, V.> ;Am J Pathol. 2005 Aug
• Molecular pathology and pathogenesis of inclusion-body myositis.
  Askanas, V., Engel, W.K.> ;Microsc Res Tech. 2005 Jul
• Mutant ubiquitin UBB+1 is accumulated in sporadic inclusion-body myositis muscle fibers.
  Fratta, P., Engel, W.K., Van Leeuwen, F.W., Hol, E.M., Vattemi, G., Askanas, V.> ;Neurology. 2004 Sep 28
• Ophthalmic manifestations of Wolf-Hirschhorn syndrome.
  Wu-Chen, W.Y., Christiansen, S.P., Berry, S.A., Engel, W.K., Fray, K.J., Summers, C.G.> ;J AAPOS. 2004 Aug
• Unicorns, dragons, polymyositis, and other mythical beasts.
  Askanas, V., Engel, W.K.> ;Neurology. 2004 Jul 27
• Endoplasmic reticulum stress and unfolded protein response in inclusion body myositis muscle.
  Vattemi, G., Engel, W.K., McFerrin, J., Askanas, V.> ;Am J Pathol. 2004 Jan
• Proposed pathogenetic cascade of inclusion-body myositis: importance of amyloid-beta, misfolded proteins, predisposing genes, and aging.
  Askanas, V., Engel, W.K.> ;Curr Opin Rheumatol. 2003 Nov
• Transthyretin Val122Ile, accumulated Abeta, and inclusion-body myositis aspects in cultured muscle.
  Askanas, V., Engel, W.K., McFerrin, J., Vattemi, G.> ;Neurology. 2003 Jul 22
• Unfolding story of inclusion-body myositis and myopathies: role of misfolded proteins, amyloid-beta, cholesterol, and aging.
  Askanas, V., Engel, W.K.> ;J Child Neurol. 2003 Mar
• BACE1 and BACE2 in pathologic and normal human muscle.
  Vattemi, G., Engel, W.K., McFerrin, J., Pastorino, L., Buxbaum, J.D., Askanas, V.> ;Exp Neurol. 2003 Feb
• Newest pathogenetic considerations in inclusion-body myositis: possible role of amyloid-beta, cholesterol, relation to aging and to Alzheimer's disease.
  Askanas, V., Engel, W.K.> ;Curr Rheumatol Rep. 2002 Oct
• Three lipoprotein receptors and cholesterol in inclusion-body myositis muscle.
  Jaworska-Wilczynska, M., Wilczynski, G.M., Engel, W.K., Strickland, D.K., Weisgraber, K.H., Askanas, V.> ;Neurology. 2002 Feb 12
• High injection pressure during intralesional injection of corticosteroids into capillary hemangiomas.
  Egbert, J.E., Paul, S., Engel, W.K., Summers, C.G.> ;Arch Ophthalmol. 2001 May
• Muscle-specific mutations accumulate with aging in critical human mtDNA control sites for replication.
  Wang, Y., Michikawa, Y., Mallidis, C., Bai, Y., Woodhouse, L., Yarasheski, K.E., Miller, C.A., Askanas, V., Engel, W.K., Bhasin, S., Attardi, G.> ;Proc Natl Acad Sci U S A. 2001 Mar 27
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