KeithMGottesdienerMDFACP

PubMed

• 177 citations
  MC4R agonism promotes durable weight loss in patients with leptin receptor deficiency
  Karine Clément, Heike Biebermann, I. Sadaf Farooqi, Lex H.T. Van der Ploeg, Barbara Wolters, Christine Poitou, Lia Puder, Fred T. Fiedorek, Keith Gottesdiener, Gunnar ...> ;Nature Medicine. 2018 May 1
• 43 citations
  Melanocortin 4 Receptor Pathway Dysfunction in Obesity: Patient Stratification Aimed at MC4R Agonist Treatment
  Kristin L. Ayers, Benjamin S. Glicksberg, Alastair S Garfield, Simonne Longerich, Joseph A White, Pengwei Yang, Lei Du, Thomas Chittenden, Jeffery R Gulcher, Sophie Ro...> ;The Journal of Clinical Endocrinology and Metabolism. 2018 Jul 1
• 93 citations
  Efficacy and Safety of Relamorelin in Diabetics With Symptoms of Gastroparesis: A Randomized, Placebo-Controlled Study
  Michael Camilleri, Richard W. McCallum, Jan Tack, Sharon C. Spence, Keith Gottesdiener, Fred T. Fiedorek> ;Gastroenterology. 2017 Nov 1
• 87 citations
  Relamorelin Reduces Vomiting Frequency and Severity and Accelerates Gastric Emptying in Adults With Diabetic Gastroparesis
  Anthony Lembo, Michael Camilleri, Richard W. McCallum, Ramon F. Sastre, Cristian F. Breton, Sharon C. Spence, Jeffery White, Michelle Currie, Keith Gottesdiener, Eliza...> ;Gastroenterology. 2016 Jul 1
• 5 citations
  Inhibition of prostacyclin and thromboxane biosynthesis in healthy volunteers by single and multiple doses of acetaminophen and indomethacin
  Jules I. Schwartz, Bret J. Musser, Wesley Tanaka, William Taggart, Anish Mehta, Keith Gottesdiener, Howard E. Greenberg> ;Clinical Pharmacology in Drug Development. 2015 Sep 1
• 38 citations
  Relamorelin Relieves Constipation and Accelerates Colonic Transit in a Phase 2, Placebo-Controlled, Randomized Trial.
  Andres Acosta, Michael Camilleri, Gururaj J. Kolar, Johanna Iturrino, Lawrence A. Szarka, Amy Boldingh, Duane Burton, Michael Ryks, Deborah Rhoten, Alan R. Zinsmeister...> ;Clinical Gastroenterology and Hepatology. 2015 Dec 1
• 113 citations
  RM-493, a Melanocortin-4 Receptor (MC4R) Agonist, Increases Resting Energy Expenditure in Obese Individuals
  Kong Y. Chen, Ranganath Muniyappa, Brent S. Abel, Katherine P. Mullins, Pamela Staker, Robert J. Brychta, Xiongce Zhao, Michael Ring, Tricia L. Psota, Roger D. Cone, B...> ;The Journal of Clinical Endocrinology and Metabolism. 2015 Feb 12
• 14 citations
  Diary of hot flashes reported upon occurrence: results of a randomized double-blind study of raloxifene, placebo, and paroxetine.
  James A. Simon, Julie Chandler, Keith Gottesdiener, Nicole Lazarus, Weili He, Elizabeth Rosenberg, John A. Wagner, Andrew Denker> ;Menopause. 2014 Sep 1
• 14 citations
  Pharmacokinetic–pharmacodynamic studies of the 11β-hydroxysteroid dehydrogenase type 1 inhibitor MK-0916 in healthy subjects
  D. Hamish Wright, Julie A. Stone, Tami Crumley, Larissa Wenning, Wei Zheng, Kerri Yan, Amy Y. Yang, Li Sun, Caroline Cilissen, Steven Ramael, Anne Hermanowski-Vosatka,...> ;British Journal of Clinical Pharmacology. 2013 Dec 1
• 52 citations
  Odanacatib, a selective cathepsin K inhibitor to treat osteoporosis: safety, tolerability, pharmacokinetics and pharmacodynamics--results from single oral dose studies...
  S. Aubrey Stoch, Stefan Zajic, Julie A. Stone, Deborah L. Miller, Lucas Van Bortel, Kenneth C. Lasseter, Barnali Pramanik, Caroline Cilissen, Q Liu, Lida Liu, Boyd B. ...> ;British Journal of Clinical Pharmacology. 2013 May 1
• 84 citations
  Randomized controlled phase Ib study of ghrelin agonist, RM-131, in type 2 diabetic women with delayed gastric emptying: pharmacokinetics and pharmacodynamics.
  Andrea Shin, Michael Camilleri, Irene Busciglio, Duane Burton, Elizabeth Stoner, Patrick Noonan, Keith Gottesdiener, Steven A. Smith, Adrian Vella, Alan R. Zinsmeister> ;Diabetes Care. 2013 Jan 1
• 47 citations
  Efficacy and safety of boceprevir plus peginterferon-ribavirin in patients with HCV G1 infection and advanced fibrosis/cirrhosis
  Savino Bruno, John M. Vierling, Rafael Esteban, L. Nyberg, Hugo Tanno, Zachary Goodman, Fred Poordad, Bruce R. Bacon, Keith Gottesdiener, Lisa D. Pedicone, Janice K. A...> ;Journal of Hepatology. 2013 Mar 1
• 44 citations
  Refinement of stopping rules during treatment of hepatitis C genotype 1 infection with boceprevir and peginterferon/ribavirin
  Ira M. Jacobson, Patrick Marcellin, Stefan Zeuzem, Mark S. Sulkowski, Rafael Esteban, Fred Poordad, Savino Bruno, Margaret Burroughs, Lisa D. Pedicone, Navdeep Boparai...> ;Hepatology. 2012 Aug 1
• 14 citations
  The effects of TPA023, a GABAAα2,3 subtype-selective partial agonist, on essential tremor in comparison to alcohol.
  SL de Haas, Rwm Zoethout, K Van Dyck, M De Smet, Laura B. Rosen, M. G Murphy, Keith Gottesdiener, Rik C. Schoemaker, Adam F. Cohen, Jma van Gerven> ;Journal of Psychopharmacology. 2012 Feb 1
• 11 citations
  Double-blind crossover study to assess potential differences in cytochrome P450 3A4 activity in healthy subjects receiving ondansetron plus dexamethasone, with and wit...
  S. Aubrey Stoch, Cynthia Gargano, Jack Valentine, Matthew P. Braun, M. Gail Murphy, Margaret Fedgchin, Anup K. Majumdar, Edward Pequignot, Keith Gottesdiener, Kevin J....> ;Cancer Chemotherapy and Pharmacology. 2011 Jun 1
• 41 citations
  Raltegravir: the first HIV-1 integrase strand transfer inhibitor in the HIV armamentarium
  Bach-Yen Nguyen, Robin Isaacs, Hedy Teppler, Randi Y. Leavitt, Peter Sklar, Marian Iwamoto, Larissa Wenning, Michael D. Miller, Joshua Chen, Ramon K. Kemp, Wei Xu, Rob...> ;Annals of the New York Academy of Sciences. 2011 Mar 1
• 27 citations
  Evaluation of pharmacokinetic parameters and dipeptidyl peptidase-4 inhibition following single doses of sitagliptin in healthy, young Japanese males
  Gary A. Herman, Goutam C. Mistry, Bingming Yi, Arthur J. Bergman, Amy Qiu Wang, Wei Zeng, Li Chen, Karen Snyder, Jon L. Ruckle, Patrick Larson, Michael J. Davies, Rona...> ;British Journal of Clinical Pharmacology. 2011 Mar 1
• 35 citations
  Effect of a novel histamine subtype-3 receptor inverse agonist and modafinil on EEG power spectra during sleep deprivation and recovery sleep in male volunteers.
  LM James, Robert Iannone, John Palcza, John J. Renger, Nicole Calder, Kristine Cerchio, Keith Gottesdiener, Richard Hargreaves, M. Gail Murphy, Julia Boyle, Derk-Jan Dijk> ;Psychopharmacology. 2011 Feb 8
• 11 citations
  Bioavailability of Alendronate and Vitamin D3 in an Alendronate/Vitamin D3 Combination Tablet
  Andrew Denker, Nicole Lazarus, Arturo G. Porras, Rohini Ramakrishnan, M.L. Constanzer, Boyd R. Scott, Cynthia Chavez-Eng, Eric Woolf, Lata Maganti, Patrick Larson, Kei...> ;Journal of Clinical Pharmacology. 2011 Oct 1
• 12 citations
  Bioequivalence of sitagliptin/metformin fixed-dose combination tablets and concomitant administration of sitagliptin and metformin in healthy adult subjects: a randomi...
  Elizabeth Migoya, Jutta Miller, Maria Gutierrez, Wei Zheng, Amy O. Johnson-Levonas, Q Liu, Catherine Z. Matthews, John A. Wagner, Keith Gottesdiener> ;Clinical Drug Investigation. 2010 Jan 1
• 46 citations
  Single-dose pharmacokinetics and pharmacodynamics of anacetrapib, a potent cholesteryl ester transfer protein (CETP) inhibitor, in healthy subjects.
  Rajesh Krishna, Amit Garg, Deborah Panebianco, Josee Cote, Arthur J. Bergman, Pascale Van Hoydonck, T Laethem, Kristien Van Dyck, Jingjing Chen, Cynthia Chavez-Eng, La...> ;British Journal of Clinical Pharmacology. 2009 Oct 1
• 14 citations
  Examination of the effect of increasing doses of etoricoxib on oral methotrexate pharmacokinetics in patients with rheumatoid arthritis.
  Jules I. Schwartz, Nancy G. B. Agrawal, Peggy H. Wong, Jutta L. Miller, Kenneth Bachmann, Thomas Marbury, David Hoelscher, Paul F. Cavanaugh, Keith Gottesdiener> ;Journal of Clinical Pharmacology. 2009 Oct 1
• 28 citations
  A thorough QTc study to assess the effect of sitagliptin, a DPP4 inhibitor, on ventricular repolarization in healthy subjects.
  Daniel M. Bloomfield, Rajesh Krishna, David Hreniuk, Lisa Hickey, Kalyan Ghosh, Arthur J. Bergman, Jutta Miller, Maria Gutierrez, Randall Stoltz, Keith Gottesdiener, G...> ;Journal of Clinical Pharmacology. 2009 Aug 1
• 8 citations
  The Effect of Etoricoxib on the Pharmacokinetics of Oral Contraceptives in Healthy Participants
  Jules I. Schwartz, Thomas L. Hunt, William B. Smith, Peggy H. Wong, Patrick Larson, Tami Crumley, Anish Mehta, Keith Gottesdiener, Nancy G. B. Agrawal> ;Journal of Clinical Pharmacology. 2009 Jul 1
• 129 citations
  Effect of Rifampin, a Potent Inducer of Drug-Metabolizing Enzymes, on the Pharmacokinetics of Raltegravir
  Larissa Wenning, William D. Hanley, Diana M. Brainard, Amelia S. Petry, Kalyan Ghosh, Bo Jin, Eric Mangin, Thomas Marbury, Jolene Kay Berg, Chodakewitz Jeffrey A, Juli...> ;Antimicrobial Agents and Chemotherapy. 2009 Jul 1
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