KeithRLoebMDPhD

PubMed

• CD74 is expressed in a subset of pediatric acute myeloid leukemia patients and is a promising target for therapy: a report from the Children's Oncology Group.
  Andrew J Menssen, Chad A Hudson, Todd Alonzo, Robert Gerbing, Laura Pardo, Amanda Leonti, Jacqueline A Cook, Fan-Chi Hsu, Loren L Lott, Fangyan Dai, Collette Fearing, ...> ;Haematologica. 2024 Feb 1
• Cytokine release syndrome after bronchoalveolar lavage.
  Margaret Guerriero, Feras Ally, Keith R Loeb, Viswam S Nair> ;BMC Pulmonary Medicine. 2023 Oct 16
• 2 citations
  Oncogenic role of a developmentally regulatedsplice variant.
  Siobhan S Pattwell, Sonali Arora, Nicholas Nuechterlein, Michael Zager, Keith R Loeb, Patrick J Cimino, Nikolas C Holland, Noemi Reche-Ley, Hamid Bolouri, Damian A Alm...> ;Science Advances. 2022 Oct 7
• 15 citations
  CBFA2T3-GLIS2 model of pediatric acute megakaryoblastic leukemia identifies FOLR1 as a CAR T cell target.
  Quy Le, Brandon Hadland, Jenny L Smith, Amanda Leonti, Benjamin J Huang, Rhonda Ries, Tiffany A Hylkema, Sommer Castro, Thao T Tang, Cyd N McKay, LaKeisha Perkins, Lau...> ;The Journal of Clinical Investigation. 2022 Nov 15
• 11 citations
  Therapeutic targeting of PRAME with mTCRCAR T cells in acute myeloid leukemia.
  Danielle C Kirkey, Anisha M Loeb, Sommer Castro, Cyd Nourigat McKay, LaKeisha Perkins, Laura Pardo, Amanda R Leonti, Thao T Tang, Michael R Loken, Lisa Eidenschink Bro...> ;Blood Advances. 2023 Apr 11
• 3 citations
  The impact of histological grade on outcomes in follicular lymphoma: An analysis of patients in the SEER database in the context of evolving disease classification and...
  Anisha Naik, Ted Gooley, Keith Loeb, Lorinda Soma, Stephen D Smith, Ajay Gopal, Naresh, K.> ;British Journal of Haematology. 2022 Dec 1
• 1010 citations
  The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic Neoplasms.
  Khoury, J., Solary, E., Abla, O., Akkari, Y., Alaggio, R., Apperley, J., Bejar, R., Berti, E., Busque, L., Chan, J., Chen, W., Chen, X., Chng, W., Choi, J., Colmenero,...> ;Leukemia. 2022 Jul 1
• 1 citations
  Transcutaneous ultrasound-mediated gene delivery into canine livers achieves therapeutic levels of factor VIII expression.
  Megan A Manson, Feng Zhang, Alexander Novokhodko, Chun-Yu Chen, Maura Parker, Keith R Loeb, Masaki Kajimoto, Carley Campbell, Rainer F Storb, Carol H Miao> ;Blood Advances. 2022 Jun 28
• 1 citations
  Accurate detection of subclonal variants in paired diagnosis-relapse acute myeloid leukemia samples by next generation Duplex Sequencing.
  Ashwini S Kamath-Loeb, Jiang-Cheng Shen, Michael W Schmitt, Brendan F Kohrn, Keith R Loeb, Elihu H Estey, Jin Dai, Sylvia Chien, Lawrence A Loeb, Pamela S Becker> ;Leukemia Research. 2022 Apr 1
• 20 citations
  FOXM1 drives HPV+ HNSCC sensitivity to WEE1 inhibition.
  Ahmed Diab, Hakan Gem, Jherek Swanger, Hee Yeon Kim, Kaleb Smith, Grace Zou, Sharat Raju, Michael Kao, Matthew Fitzgibbon, Keith R. Loeb, Cristina P. Rodriguez, Eduard...> ;Proceedings of the National Academy of Sciences of the United States of America. 2020 Oct 22
• 8 citations
  Targeted Sequencing Improves DIPSS-Plus Prognostic Scoring in Myelofibrosis Patients Undergoing Allogeneic Transplantation.
  Emily A. Stevens, Isaac C. Jenkins, Lan Beppu, Qing Zhang, Rachel B. Salit, Keith R. Loeb, H. Joachim Deeg, Jerald P. Radich> ;Biology of Blood and Marrow Transplantation. 2020 Jul 1
• 36 citations
  Comprehensive Transcriptome Profiling of Cryptic CBFA2T3-GLIS2 Fusion-Positive AML Defines Novel Therapeutic Options: A COG and TARGET Pediatric AML Study.
  Jenny L. Smith, Rhonda E. Ries, Tiffany A. Hylkema, Todd A. Alonzo, Robert B. Gerbing, Marianne Santaguida, Lisa Eidenschink Brodersen, Laura Pardo, Carrie L. Cummings...> ;Clinical Cancer Research. 2020 Feb 1
• 11 citations
  A high-resolution landscape of mutations in the BCL6 super-enhancer in normal human B cells.
  Jiang Cheng Shen, Ashwini S. Kamath-Loeb, Brendan F. Kohrn, Keith R. Loeb, Bradley D. Preston, Lawrence A. Loeb> ;Proceedings of the National Academy of Sciences of the United States of America. 2019 Dec 3
• 6 citations
  Transcutaneous Ultrasound-Mediated Nonviral Gene Delivery to the Liver in a Porcine Model.
  Dominic M. Tran, Feng Zhang, Kyle P. Morrison, Keith R. Loeb, James Harrang, Masaki Kajimoto, Francisco P. Chávez, Li Wu, Carol H. Miao> ;Molecular Therapy. Methods & Clinical Development. 2019 Jul 26
• 6 citations
  Insertional mutagenesis using the Sleeping Beauty transposon system identifies drivers of erythroleukemia in mice.
  Keith R. Loeb, Bridget T. Hughes, Brian M. Fissel, Nyka J. Osteen, Sue E. Knoblaugh, Jonathan E. Grim, Luke J. Drury, Aaron L. Sarver, Adam J. Dupuy, Bruce E. Clurman> ;Scientific Reports. 2019 Apr 2
• 6 citations
  Whole-genome sequencing of esophageal adenocarcinoma in Chinese patients reveals distinct mutational signatures and genomic alterations.
  James Y. Dai, Xiaoyu Wang, Matthew F. Buas, Chengjuan Zhang, Jie Ma, Bing Wei, Yin Li, Baosheng Zhao, Teresa S Hyun, Xueyan Chen, Keith R Loeb, Robert D. Odze, Lena Ya...> ;Communications Biology. 2018 Oct 24
• 6 citations
  Ultrasound-Mediated Gene Therapy in Swine Livers Using Single-Element, Multi-lensed, High-Intensity Ultrasound Transducers.
  Misty L. Noble-Vranish, Shuxian Song, Kyle P. Morrison, Dominic M. Tran, Ryan R. Sun, Keith R. Loeb, George W. Keilman, Carol H. Miao> ;Molecular Therapy. Methods & Clinical Development. 2018 Sep 21
• 11 citations
  Pilot study of lithium to restore intestinal barrier function in severe graft-versus-host disease.
  Gideon Steinbach, David M. Hockenbery, Gerwin Huls, Terry Furlong, David Myerson, Keith R. Loeb, Jesse R. Fann, Christina Castilla-Llorente, George B. McDonald, Paul J...> ;Plos One. 2017 Aug 17
• 3072 citations
  Massively parallel digital transcriptional profiling of single cells
  Grace X.Y. Zheng, Jessica M. Terry, Phillip Belgrader, Paul Ryvkin, Zachary Bent, Ryan Wilson, Solongo B. Ziraldo, Tobias Daniel Wheeler, Geoffrey P. McDermott, Junjie...> ;Nature Communications. 2017 Jan 16
• 3 citations
  Corrigendum: Wild-type microglia do not reverse pathology in mouse models of Rett syndrome.
  Jieqi Wang, Jan Eike Wegener, Teng-Wei Huang, Smitha Sripathy, Héctor De Jesús-Cortés, Pin Xu, Stephanie Tran, Whitney Knobbe, Vid Leko, Jeremiah K. Britt, Ruth Starwa...> ;Nature. 2015 Sep 24
• 201 citations
  Outcomes of acute leukemia patients transplanted with naive T cell–depleted stem cell grafts
  Marie Bleakley, Shelly Heimfeld, Keith R. Loeb, Lori Jones, Colette Chaney, Stuart Seropian, Ted Gooley, Franziska Sommermeyer, Stanley R. Riddell, Warren D. Shlomchik> ;The Journal of Clinical Investigation. 2015 Jul 1
• 7 citations
  Comparative analysis of flow cytometry and morphology for the detection of acute myeloid leukaemia cells in cerebrospinal fluid
  Keith R. Loeb, Sindhu Cherian, Pamela S. Becker, Roland B. Walter, Janis L. Abkowitz, Frederick R. Appelbaum, Brent L. Wood, Elihu H. Estey> ;British Journal of Haematology. 2016 Jan 1
• 103 citations
  Wild-type microglia do not reverse pathology in mouse models of Rett syndrome
  Jieqi Wang, Jan Eike Wegener, Teng-Wei Huang, Smitha Sripathy, Héctor De Jesús-Cortés, Pin Xu, Stephanie Tran, Whitney Knobbe, Vid Leko, Jeremiah K. Britt, Ruth Starwa...> ;Nature. 2015 May 21
• 24 citations
  Central Nervous System Involvement in Acute Myeloid Leukemia Patients Undergoing Hematopoietic Cell Transplantation
  Merav Bar, Weigang Tong, Megan Othus, Keith R. Loeb, Elihu H. Estey> ;Biology of Blood and Marrow Transplantation. 2015 Mar 1
• 16 citations
  Fibrosing cholestatic hepatitis C after hematopoietic cell transplantation: report of 3 fatal cases.
  Ashley T. Evans, Keith R. Loeb, Howard M. Shulman, Sajida Hassan, Wan Chong Qiu, David M. Hockenbery, George N. Ioannou, Thomas R. Chauncey, David R. Gretch, George B....> ;The American Journal of Surgical Pathology. 2015 Feb 1
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Abstracts/Posters

• CBFA2T3-GLIS2 induces Malignant Transformation of Primitive CD34+ Cord Blood Cells and Recapitulates Infant Megakaryocytic Leukemia
  Keith R. Loeb, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019