KelseyBertrandMD

Pediatric Hematology & Oncology • Memphis, TN

Assistant Professor

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Office
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105
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Education & Training

Baylor College of MedicineFellowship, Pediatric Hematology/Oncology, 2017 - 2020
Cleveland Clinic FoundationResidency, Pediatrics, 2014 - 2017
The Hospital for Sick ChildrenPostdoctoral fellowship, Mechanisms of drug resistance in medulloblastoma, 2013 - 2014
The University of Queensland Medical SchoolClass of 2013
University of Toronto, The Hospital for Sick ChildrenMSc, Epigenetics of medulloblastoma, 2007 - 2009
University of GuelphBSc, Biological Sciences, 2003 - 2007

Certifications & Licensure

TN State Medical License 2021 - 2025
TX State Medical License 2020 - 2023
OH State Medical License 2014 - 2019
American Board of Pediatrics Pediatrics
American Board of Pediatrics Pediatric Hematology-Oncology

Publications & Presentations

PubMed

Development of Chromosome 1q+ Specific Treatment for Highest Risk Pediatric Posterior Fossa Ependymoma.
Andrea M Griesinger, Annaliese J Calzadilla, Enrique Grimaldo, Andrew M Donson, Vladimir Amani, Angela M Pierce, Jenna Steiner, Soudabeh Kargar, Natalie J Serkova, Kel...> ;Clinical Cancer Research. 2024 Apr 15
An ERK5-PFKFB3 axis regulates glycolysis and represents a therapeutic vulnerability in pediatric diffuse midline glioma.
Plute, T., Felker, J. T., Stephanie M Casillo, Taylor A Gatesman, Akanksha Chilukuri, Srinidhi Varadharajan, Brenden J Johnson, Daniel R David Premkumar, Esther P Jane...> ;Cell Reports. 2024 Jan 23
1 citations
Recent Advancements in Ependymoma: Challenges and Therapeutic Opportunities.
Kelsey C Bertrand, Paul Klimo> ;Pediatric Neurosurgery. 2023 Jan 1
Top advances of the year: Pediatric oncology.
Alberto S Pappo, Seth E Karol, Kelsey C Bertrand> ;Cancer. 2022 Oct 1
1 citations
Author Correction: Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome.
Rich, J., Brian J Golbourn, Matthew E Halbert, Katharine Halligan, Srinidhi Varadharajan, Brian Krug, Nneka E Mbah, Nisha Kabir, Ann-Catherine J Stanton, Abigail L Loc...> ;Nature Cancer. 2022 Jul 1
16 citations
Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome.
Felker, J. T., Brian J Golbourn, Matthew E Halbert, Katharine Halligan, Srinidhi Varadharajan, Brian Krug, Nneka E Mbah, Nisha Kabir, Ann-Catherine J Stanton, Abigail ...> ;Nature Cancer. 2022 May 1
5 citations
Durable Response to Larotrectinib in a Child With Histologic Diagnosis of Recurrent Disseminated Ependymoma Discovered to Harbor an NTRK2 Fusion: The Impact of Integra...
Ross Mangum, Jacquelyn Reuther, Kelsey C. Bertrand, Raghu Chandramohan, Marcia Kukreja, Arnold C. Paulino, Donna M. Muzny, Jianhong Hu, Richard A. Gibbs, Daniel J. Cur...> ;JCO Precision Oncology. 2021 Jul 28
38 citations
ZFTA–RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma
Amir Arabzade, Yanhua Zhao, Srinidhi Varadharajan, Hsiao-Chi Chen, Selin Jessa, Bryan Rivas, Austin J. Stuckert, Minerva Solis, Alisha Kardian, Dana Tlais, Brian Golbo...> ;Cancer Discovery. 2021 Mar 19
2 citations
Weighing ependymoma as an epigenetic disease
Austin J. Stuckert, Kelsey C. Bertrand, P. Wang, Amy M. Smith, Stephen C. Mack> ;Journal of Neuro-Oncology. 2020 Sep 22
2 citations
Sub-group, Sub-type, and Cell-type Heterogeneity of Ependymoma.
Stephen C. Mack, Kelsey C. Bertrand> ;Cancer Cell. 2020 Jul 13
7 citations
BCOR-CCNB3 fusion-positive clear cell sarcoma of the kidney.
Hyojeong Han, Kelsey C. Bertrand, Kalyani R. Patel, Kevin E. Fisher, Angshumoy Roy, Jodi A. Muscal, Rajkumar Venkatramani> ;Pediatric Blood & Cancer. 2020 Apr 1
3 citations
Invited Review: The role and contribution of transcriptional enhancers in brain cancer.
Amir Arabzade, Austin J. Stuckert, Kelsey C. Bertrand, Stephen C. Mack> ;Neuropathology and Applied Neurobiology. 2020 Feb 1
9 citations
Targeting NAD+ Biosynthesis Overcomes Panobinostat and Bortezomib-Induced Malignant Glioma Resistance.
Esther P. Jane, Daniel R. Premkumar, Swetha Thambireddy, Brian Golbourn, Sameer Agnihotri, Kelsey C. Bertrand, Stephen C. Mack, Max I. Myers, Ansuman Chattopadhyay, D....> ;Molecular Cancer Research. 2020 Jan 1
60 citations
Erratum: Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas (Cancer Cell (2019) 35(5) (782–797.e8), (S15356108193019...
Brian Krug, Nicolas De Jay, Ashot S. Harutyunyan, Shriya Deshmukh, Dylan M. Marchione, Paul Guilhamon, Kelsey C. Bertrand, Leonie G. Mikael, Melissa K. McConechy, Caro...> ;Cancer Cell. 2019 Sep 16
39 citations
Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas.
Brian Krug, Nicolas De Jay, Ashot S Harutyunyan, Shriya Deshmukh, Dylan M Marchione, Paul Guilhamon, Kelsey C Bertrand, Leonie G Mikael, Melissa K McConechy, Carol C L...> ;Cancer Cell. 2019 May 13
68 citations
Chromatin landscapes reveal developmentally encoded transcriptional states that define human glioblastoma.
Stephen C. Mack, Irtisha Singh, Xiuxing Wang, Rachel A. Hirsch, Q Wu, Rosie Villagomez, Jean A. Bernatchez, Zhe Zhu, Ryan C. Gimple, Leo J.Y. Kim, Andrew R. Morton, Si...> ;The Journal of Experimental Medicine. 2019 May 6
8 citations
A functional genomics approach to identify pathways of drug resistance in medulloblastoma.
Kelsey C. Bertrand, Claudia C. Faria, Patryk Skowron, Amanda Luck, Livia Garzia, Xiaochong Wu, Sameer Agnihotri, Christian A. Smith, Michael D. Taylor, Stephen C. Mack...> ;Acta Neuropathologica Communications. 2018 Dec 27
9 citations
Pediatric ependymoma: current treatment and newer therapeutic insights.
Soumen Khatua, Ross Mangum, Kelsey C. Bertrand, Wafik Zaky, David McCall, Stephen C. Mack> ;Future Oncology. 2018 Nov 12
147 citations
Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling
Stephen C. Mack, Kristian W. Pajtler, Lukas Chavez, Konstantin Okonechnikov, Kelsey C. Bertrand, Xiuxing Wang, Serap Erkek, Alexander J. Federation, Anne Song, Christi...> ;Nature. 2018 Jan 4
32 citations
Spinal Myxopapillary Ependymomas Demonstrate a Warburg Phenotype.
Stephen C. Mack, Sameer Agnihotri, Kelsey C. Bertrand, Xin Wang, David Shih, Hendrik Witt, Nadia Hill, Kory Zayne, Mark Barszczyk, Vijay Ramaswamy, Marc Remke, Yuan Ya...> ;Clinical Cancer Research. 2015 Aug 15
21 citations
Identification of alsterpaullone as a novel small molecule inhibitor to target group 3 medulloblastoma.
Claudia C. Faria, Sameer Agnihotri, Stephen C. Mack, Brian Golbourn, Roberto J. Diaz, Samantha Olsen, Melissa Bryant, Matthew Bebenek, Xin Wang, Kelsey C. Bertrand, Mi...> ;Oncotarget. 2015 May 28
31 citations
Transcriptional profiling of GBM invasion genes identifies effective inhibitors of the LIM kinase-Cofilin pathway.
Jun-Bum Park, Sameer Agnihotri, Brian Golbourn, Kelsey C. Bertrand, Amanda Luck, Nesrin Sabha, Christian A. Smith, Sara A. Byron, Gelareh Zadeh, Sidney Croul, Michael ...> ;Oncotarget. 2014 Sep 5
Leukocytosis in an Infant With Down Syndrome
Sylvia Doan, Kelsey C. Bertrand, Jenson C. S. Ma, Aman Chauhan, Rajasekharan Warrier> ;Clinical Pediatrics. 2014 Mar 20
412 citations
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy
Stephen C. Mack, Hendrik Witt, Rosario M. Piro, L. Gu, Scott Zuyderduyn, Adrian M. Stütz, Xin Wang, Marco Gallo, Livia Garzia, Kory Zayne, Xiaoyang Zhang, Vijay Ramasw...> ;Nature. 2014 Feb 27
20 citations
Hippocampal-sparing radiotherapy: the new standard of care for World Health Organization grade II and III gliomas?
Mark B. Pinkham, K.C. Bertrand, Sara H. Olson, Dannie Zarate, Joanne Oram, A. Pullar, Matthew Foote> ;Journal of Clinical Neuroscience. 2014 Jan 1
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