KenMKunisakiMDMS

Pulmonology • Minneapolis, MN

Critical Care Medicine, Pleural Disease, Sleep Medicine

Associate Professor of Medicine University of Minnesota

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Office
1 Veterans Dr
Minneapolis, MN 55417
Phone+1 612-725-2000
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Education & Training

University of MinnesotaM.S., Clinical Research, 2014
University of MinnesotaFellowship, Pulmonary Disease and Critical Care Medicine, 2003 - 2007
University of MinnesotaResidency, Internal Medicine/Pediatrics, 1999 - 2003
Ohio State University College of MedicineClass of 1999

Certifications & Licensure

MN State Medical License 2000 - 2024
American Board of Internal Medicine Critical Care Medicine
American Board of Internal Medicine Pulmonary Disease

Awards, Honors, & Recognition

Teacher of the Year Pulmonary and Critical Care Fellowship, University of Minnesota, 2018
Outstanding Educator in Research Award Minneapolis VA Depertment of Medicine, 2018
Sreedhar Nair Early Stage Investigator Award in COPD American Thoracic Society, 2017
Education Excellence Award Minneapolis VA Health Care System, 2011
Fellow American College of Chest Physicians, 2009
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Clinical Trials

Strategic Timing of Antiretroviral Treatment Start of enrollment: 2009 Apr 15
Completed
Phase 4
Effect of Supplemental Vitamin D on Skeletal Muscle Function in Chronic Obstructive Pulmonary Disease (COPD) Patients Start of enrollment: 2009 Jun 01
Completed
Phase 3
Pulmonary Substudy: A Substudy of Strategic Timing of AntiRetroviral Treatment (START) Start of enrollment: 2010 Mar 01
Completed
Evaluating the Safety and Efficacy of Anti-Influenza Intravenous Hyperimmune Immunoglobulin (IVIG) in Adults Hospitalized With Influenza Start of enrollment: 2015 Jan 01
Completed
Phase 3
Beta-Blockers for the Prevention of Acute Exacerbations of Chronic Obstructive Pulmonary Disease Start of enrollment: 2016 May 01
Terminated
Phase 3
Service and Health Among Deployed Veterans Start of enrollment: 2018 Mar 08
Enrolling by invitation
The Impact of Low Flow Nocturnal Oxygen Therapy on Hospital Admissions and Mortality in Patients With Heart Failure and Central Sleep Apnea Start of enrollment: 2019 Apr 15
Terminated
Phase 3
Video Telehealth Pulmonary Rehabilitation to Reduce Hospital Readmission in Chronic Obstructive Pulmonary Disease Start of enrollment: 2022 Jun 28
Recruiting
Not Applicable
Roles: Contact
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Publications & Presentations

PubMed

Influence of Impaired Diffusing Capacity and Sleep-disordered Breathing on Nocturnal Hypoxemia and Health Outcomes in Men with and without HIV.
Sanjay R Patel, Gypsamber D'Souza, Alison Morris, Joseph B Margolick, Todd T Brown, Sarath Raju, Trishul Siddharthan, Meredith C McCormack, Ken M Kunisaki, Joshua Hyon...> ;Annals of the American Thoracic Society. 2024 Mar 18
The Intersections of COVID-19, HIV, and Race/Ethnicity: Machine Learning Methods to Identify and Model Risk Factors for Severe COVID-19 in a Large U.S. National Dataset.
Koraishy, F. M., Miranda Kunz, Kollin W Rott, Eric Hurwitz, Ken Kunisaki, Jing Sun, Kenneth J Wilkins, Jessica Y Islam, Rena Patel, Sandra E Safo> ;AIDS and Behavior. 2024 Feb 7
Association between P-pulmonale and respiratory morbidity in COPD: a secondary analysis of the BLOCK-COPD trial.
Takudzwa Mkorombindo, Sharon X Ling, Erika S Helgeson, David M MacDonald, Krystle Pew, Helen Voelker, Vera Bittner, Ken M Kunisaki, Mark T Dransfield, Wade, R. C., R C...> ;BMC Pulmonary Medicine. 2023 Nov 9
Guideline-discordant inhaler regimens after COPD hospitalization: associations with rurality, drive time to care, and fragmented care - a United States cohort study.
Arianne K Baldomero, Ken M Kunisaki, Chris H Wendt, Carrie Henning-Smith, Hildi J Hagedorn, Ann Bangerter, R Adams Dudley> ;Lancet Regional Health. Americas. 2023 Oct 1
Associations between GrimAge acceleration and pulmonary function in the Coronary Artery Risk Development in Young Adults (CARDIA) study.
Brian T Joyce, Xuefen Chen, Tao Gao, Yinan Zheng, Drew R Nannini, Lei Liu, Benjamin E Henkle, Ravi Kalhan, George Washko, Ken M Kunisaki, Bharat Thyagarajan, Douglas E...> ;Epigenomics. 2023 Jul 1
3 citations
HIV-associated lung disease.
Ioannis Konstantinidis, Kristina Crothers, Ken M Kunisaki, M Bradley Drummond, Thomas Benfield, Heather J Zar, Laurence Huang, Alison Morris> ;Nature Reviews. Disease Primers. 2023 Jul 27
Bilirubin-associated single nucleotide polymorphism (SNP) and respiratory health outcomes: a mendelian randomization study.
Arianne K Baldomero, David M MacDonald, Adam Kaplan, Eric Lock, Michael H Cho, Russell Bowler, Lucas Gillenwater, Ken M Kunisaki, Chris H Wendt> ;Respiratory Research. 2023 Jul 20
Cognitive function and inhaler technique following recovery from exacerbations of COPD.
Benjamin E Henkle, Rebecca L Freese, Mary Dahlheimer, Catherine Kane, Karin F Hoth, Ken M Kunisaki> ;ERJ Open Research. 2023 Jul 1
1 citations
Elevated Levels of Interleukin-1β and Interleukin-10 Are Associated With Faster Lung Function Decline in People With Well-Treated Human Immunodeficiency Virus.
Rebekka F Thudium, Nicoline S Arentoft, Hedda Hoel, Shoaib Afzal, Jakob H von Stemann, Julie L Forman, Jon T Wilcke, Thomas Benfield, Marius Trøseid, Álvaro H Borges, ...> ;The Journal of Infectious Diseases. 2023 Oct 18
Cardiovascular Autonomic Function and Incident Chronic Obstructive Pulmonary Disease Hospitalizations in Atherosclerosis Risk in Communities.
David M MacDonald, Yuekai Ji, Selcuk Adabag, Alvaro Alonso, Lin Yee Chen, Benjamin E Henkle, Stephen P Juraschek, Faye L Norby, Pamela L Lutsey, Ken M Kunisaki> ;Annals of the American Thoracic Society. 2023 Oct 1
Pulmonary Function and Quality of Life in Aging Men With and Without HIV from the Multicenter AIDS Cohort Study.
Mona Abdo, Ken M Kunisaki, Alison Morris, Valentina Stosor, Dong Chang, Gypsyamber D'Souza, Kristina Crothers, Madiha Abdel-Maksoud, Carolyn DiGuiseppi, Todd T Brown, ...> ;AIDS Research and Human Retroviruses. 2023 Dec 1
1 citations
Challenges and Recommendations for Improving Access to Evidence-Based COPD Management among Rural Veterans: Rural Primary Care Provider Perspectives.
Talitha Wilson, R Adams Dudley, Ken M Kunisaki, Chris H Wendt, Carrie Henning-Smith, Hildi J Hagedorn, Arianne K Baldomero> ;Journal of General Internal Medicine. 2023 Sep 1
Pneumoproteins and biomarkers of inflammation and coagulation do not predict rapid lung function decline in people living with HIV.
David M MacDonald, Sarah Samorodnitsky, Chris H Wendt, Jason V Baker, Gary Collins, Monica Kruk, Eric F Lock, Roger Paredes, Selvamuthu Poongulali, Danielle O Weise, A...> ;Scientific Reports. 2023 Mar 23
2 citations
Do sleep disturbances contribute to comorbidities in HIV?
Ken M Kunisaki> ;Current Opinion in HIV and AIDS. 2023 Mar 1
Lung proteome and metabolome endotype in HIV-associated obstructive lung disease.
Sarah Samorodnitsky, Eric F Lock, Monica Kruk, Alison Morris, Janice M Leung, Ken M Kunisaki, Timothy J Griffin, Chris H Wendt> ;ERJ Open Research. 2023 Mar 1
6 citations
Faster lung function decline in people living with HIV despite adequate treatment: a longitudinal matched cohort study.
Rebekka Faber Thudium, Andreas Ronit, Shoaib Afzal, Yunus Çolak, Julie Lyng Forman, Fernando Mendo, Fabian Chen, Vicente Estrada, Nagalingeswaran Kumarasamy, Børge G N...> ;Thorax. 2023 Jun 1
3 citations
Association between inflammatory biomarker profiles and cardiovascular risk in individuals with and without HIV.
Luxsena Sukumaran, Ken M Kunisaki, Nicholas Bakewell, Alan Winston, Patrick W G Mallon, Nicki Doyle, Jane Anderson, Marta Boffito, Lewis Haddow, Frank A Post, Jaime H ...> ;AIDS. 2023 Mar 15
1 citations
Current Challenges and Solutions for Clinical Management and Care of People with HIV: Findings from the 12th Annual International HIV and Aging Workshop.
Xiaoying Yu, Judith D Lobo, Erin Sundermann, Darren J Baker, Russell P Tracy, George A Kuchel, Kathryn E Stephenson, Scott L Letendre, Bruce Brew, Lucette A Cysique, S...> ;AIDS Research and Human Retroviruses. 2023 Jan 1
3 citations
Drive Time and Receipt of Guideline-Recommended Screening, Diagnosis, and Treatment.
Arianne K Baldomero, Ken M Kunisaki, Chris H Wendt, Ann Bangerter, Susan J Diem, Kristine E Ensrud, David B Nelson, Carrie Henning-Smith, Bradley A Bart, Patrick Hamme...> ;JAMA Network Open. 2022 Nov 1
Pulmonary and physical function limitations in aging men with and without HIV from the Multicenter AIDS Cohort Study (MACS).
Mona Abdo, Ken M Kunisaki, Alison Morris, Valentina Stosor, Dong Chang, Gypsyamber D'Souza, Kristina Crothers, Madiha Abdel-Maksoud, Carolyn DiGuiseppi, Todd T Brown, ...> ;Annals of Epidemiology. 2022 Dec 1
16 citations
Time-Dependent Risk of Cardiovascular Events Following an Exacerbation in Patients With Chronic Obstructive Pulmonary Disease: Post Hoc Analysis From the IMPACT Trial.
Mark T Dransfield, Gerard J Criner, David M G Halpin, MeiLan K Han, Benjamin Hartley, Ravi Kalhan, Peter Lange, David A Lipson, Fernando J Martinez, Dawn Midwinter, Da...> ;Journal of the American Heart Association. 2022 Sep 20
2 citations
Biomarker associations with insomnia and secondary sleep outcomes in persons with and without HIV in the POPPY-Sleep substudy: a cohort study.
Nicholas Bakewell, Caroline A Sabin, Riya Negi, Alejandro Garcia-Leon, Alan Winston, Memory Sachikonye, Nicki Doyle, Susan Redline, Patrick W G Mallon, Ken M Kunisaki> ;Sleep. 2022 Dec 12
1 citations
Association Between HIV and Prevalence and Manifestations of Asthma: Analysis of the Multicenter AIDS Cohort Study and Women's Interagency HIV Study.
M Bradley Drummond, Andrew Edmonds, Catalina Ramirez, Valentina Stosor, Igor Z Barjaktarevic, Alison Morris, Meredith C McCormack, Surya P Bhatt, Maria L Alcaide, Sush...> ;Journal of Acquired Immune Deficiency Syndromes. 2022 Dec 15
1 citations
Beyond Access: Factors Associated With Spirometry Underutilization Among Patients With a Diagnosis of COPD in Urban Tertiary Care Centers.
Arianne K Baldomero, Ken M Kunisaki, Ann Bangerter, David B Nelson, Chris H Wendt, Spyridon Fortis, Hildi Hagedorn, R Adams Dudley> ;Chronic Obstructive Pulmonary Diseases. 2022 Oct 26
5 citations
Pulmonary Function Trajectories in People with HIV: Analysis of the Pittsburgh HIV Lung Cohort.
Ioannis Konstantinidis, Shulin Qin, Meghan Fitzpatrick, Cathy Kessinger, Heather Gentry, Deborah McMahon, R Dawn Weinman, Phyllis Tien, Laurence Huang, Meredith McCorm...> ;Annals of the American Thoracic Society. 2022 Dec 1
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Journal Articles

Unauthorized Online Sales of Secondhand Continuous Positive Airway Pressure Devices
Ken Kunisaki, MD, JAMA

Press Mentions

PRE-PROOF Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation PRE-PROOFAugust 23rd, 2022
Living with HIV Associated with a Fivefold Increase in the Risk of InsomniaJanuary 25th, 2021
Study: Men with HIV at Greater Risk of Abnormal Lung FunctionJuly 24th, 2020
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Grant Support

Sleep, Aging, and HIV Infection Cohort StudyNational Heart, Lung, and Blood Institute2016–Present
Effects of HIV Antiretroviral Therapy on Pulmonary Function in a Randomized TrialNational Heart, Lung and Blood Institute2009–Present
Tryptophan and the Plasma Metabolome in HIV-Associated Chronic Obstructive PUlmonary DiseaseUniversity of Minnesota Developmental Center for AIDS Research2014–2015
Sleep Apnea Streamlined Assesment and TreatmentVeterans Integrated Service Network 232011–2013