KennethOffitMD

Professor, Medicine, Weill Cornell Medical College

Overview of Dr. Offit

Dr. Kenneth Offit is an oncologist in New York, NY and is affiliated with Memorial Sloan Kettering Cancer Center. He received his medical degree from Harvard Medical School and has been in practice 35 years. Dr. Offit accepts several types of health insurance, listed below. He is one of 464 doctors at Memorial Sloan Kettering Cancer Center who specialize in Oncology. He has more than 100 publications and over 500 citings.

Office
Memorial Sloan Kettering Cancer Center New York
1275 York Avenue
New York, NY 10021
Book by Phone+1(424) 285-1384
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Education & Training

Memorial Sloan Kettering Cancer CenterFellowship, Hematology and Medical Oncology, 1986 - 1988
Memorial Sloan Kettering Cancer CenterFellowship, Hematology and Medical Oncology, 1985 - 1986
Zucker School of Medicine at Hofstra/Northwell at Lenox Hill HospitalResidency, Internal Medicine, 1982 - 1985
Harvard Medical SchoolClass of 1982

Certifications & Licensure

FL State Medical License 2021 - Present
NY State Medical License 1984 - 2025
NJ State Medical License 2012 - 2025
CT State Medical License 2023 - 2025
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

America's Top Doctors Castle Connolly, 2003-2014
Top Doctors: New York Metro Area Castle Connolly, 2002-2014
New York Magazine: Top Doctors Castle Connolly, 2002-2008, 2014
America's Top Doctors for Cancer Castle Connolly, 2005-2013
Elected Member The American Society for Clinical Investigation, 2000
Super Doctor SuperDoctors.com
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Clinical Trials

Ascertainment of Peripheral Blood or Saliva Samples for Genetic Epidemiology Studies of Familial Cancers Start of enrollment: 1994 Dec 01
Active, not recruiting
Clinical Significance of Germline BRCA Mutations Start of enrollment: 1996 Jul 01
Active, not recruiting
Germline Alterations of Tumor Susceptibility Genes in New York Cancer Patients Start of enrollment: 2000 Mar 01
Active, not recruiting
Not Applicable
Ascertainment of Saliva or Blood Samples For Genetic Epidemiology Studies of Cancer and Aging Start of enrollment: 2006 Sep 01
Completed
Identification of New Colorectal Cancer Genes Start of enrollment: 1998 Feb 10
Completed
Ascertainment of Families for Genetic Studies of Familial Lymphoproliferative Disorders Start of enrollment: 2000 Jul 01
Recruiting
Anonymous Testing of Pathology Specimens for BRCA Mutations in Ashkenazi Jewish Individuals Who Have Cancer Start of enrollment: 2000 Jul 01
Withdrawn
Germline BRCA1 and BRCA2 Mutations in Jewish Women Affected by Breast Cancer Start of enrollment: 1997 Mar 01
Completed
BRCA Founder OutReach (BFOR) Study Start of enrollment: 2017 Nov 10
Active, not recruiting
Discovering New Genetic Markers in Adults and Children Who May Be At Risk for Hereditary Forms of Cancer Start of enrollment: 2019 Apr 17
Recruiting
An Intervention to Increase Genetic Testing in Families Who May Share a Gene Mutation Related to Cancer Risk Start of enrollment: 2022 Dec 01
Recruiting
Not Applicable
Roles: Principal Investigator, Contact
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Publications & Presentations

PubMed

Universal germline genetic testing in patients with hematologic malignancies using DNA isolated from nail clippings.
Ozge Ceyhan-Birsoy, Elise Fiala, Satshil Rana, Margaret Sheehan, Jennifer Kennedy, Zarina Yelskaya, Vikas Rai, Yirong Li, Ciyu Yang, Donna Wong, Ivelise Rijo, Jacklyn ...> ;Haematologica. 2024 Apr 4
Large-scale genome-wide association study of 398,238 women unveils seven novel loci associated with high-grade serous epithelial ovarian cancer risk.
Daniel R Barnes, Jonathan P Tyrer, Joe Dennis, Goska Leslie, Manjeet K Bolla, Michael Lush, Amber M Aeilts, Kristiina Aittomäki, Nadine Andrieu, Irene L Andrulis, Hoda...> ;Medrxiv. 2024 Mar 4
Differences in polygenic score distributions in European ancestry populations: implications for breast cancer risk prediction.
Kristia Yiangou, Nasim Mavaddat, Joe Dennis, Maria Zanti, Qin Wang, Manjeet K Bolla, Mustapha Abubakar, Thomas U Ahearn, Irene L Andrulis, Hoda Anton-Culver, Natalia N...> ;Medrxiv. 2024 Feb 13
Pathogenic germline variants in non-BRCA1/2 homologous recombination genes in ovarian cancer: Analysis of tumor phenotype and survival.
Kahn, R., Selenica, P., Boerner, T., Roche, K., Xiao, Y., Sia, T., Maio, A., Kemel, Y., Sheehan, M., Salo-Mullen, E., Breen, K., Zhou, Q., Iasonos, A., Grisham, R., O'...> ;Gynecologic Oncology. 2024 Jan 1
2 citations
Development of a novel measure of advanced cancer patients' perceived utility of secondary germline findings from tumor genomic profiling.
Jada G Hamilton, Ibrahim H Shah, Caroline Salafia, Elizabeth Schofield, Margaux Genoff Garzon, Kechna Cadet, Zsofia K Stadler, Jennifer L Hay, Kenneth Offit, Mark E Ro...> ;PEC Innovation. 2023 Dec 1
2 citations
Nucleotide excision repair deficiency is a targetable therapeutic vulnerability in clear cell renal cell carcinoma.
Aurel Prosz, Haohui Duan, Viktoria Tisza, Pranshu Sahgal, Sabine Topka, Gregory T Klus, Judit Börcsök, Zsofia Sztupinszki, Timothy Hanlon, Miklos Diossy, Laura Vizkele...> ;Scientific Reports. 2023 Nov 23
3 citations
Pathogenic germline variants in patients with endometrial cancer of diverse ancestry.
Ying L Liu, Sushmita Gordhandas, Kanika Arora, Eric Rios-Doria, Karen A Cadoo, Amanda Catchings, Anna Maio, Yelena Kemel, Margaret Sheehan, Erin Salo-Mullen, Qin Zhou,...> ;Cancer. 2024 Feb 15
11 citations
NCCN Guidelines® Insights: Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic, Version 2.2024.
Mary B Daly, Tuya Pal, Kara N Maxwell, Jane Churpek, Wendy Kohlmann, Zahraa AlHilli, Banu Arun, Saundra S Buys, Heather Cheng, Susan M Domchek, Susan Friedman, Veda Gi...> ;Journal of the National Comprehensive Cancer Network. 2023 Oct 1
2 citations
Neoplasia risk in patients with Lynch syndrome treated with immune checkpoint blockade.
Emily C Harrold, Michael B Foote, Benoit Rousseau, Henry Walch, Yelena Kemel, Allison L Richards, Fergus Keane, Andrea Cercek, Rona Yaeger, Dana Rathkopf, Neil H Segal...> ;Nature Medicine. 2023 Oct 1
Correction: Distinct germline genetic susceptibility profiles identified for common non-Hodgkin lymphoma subtypes.
Sonja I Berndt, Joseph Vijai, Yolanda Benavente, Nicola J Camp, Alexandra Nieters, Zhaoming Wang, Karin E Smedby, Geffen Kleinstern, Henrik Hjalgrim, Caroline Besson, ...> ;Leukemia. 2023 Oct 1
1 citations
Germline Pathogenic Variants and Genetic Counseling by Ancestry in Patients With Epithelial Ovarian Cancer.
Tiffany Y Sia, Anna Maio, Yelena M Kemel, Kanika S Arora, Sushmita B Gordhandas, Ryan M Kahn, Erin E Salo-Mullen, Margaret A Sheehan, Prince Rainier Tejada, Chaitanya ...> ;JCO Precision Oncology. 2023 Sep 1
2 citations
Genomic Profiling Reveals Germline Predisposition and Homologous Recombination Deficiency in Pancreatic Acinar Cell Carcinoma.
Diana Mandelker, Antonio Marra, Binbin Zheng-Lin, Pier Selenica, Juan Blanco-Heredia, Yingjie Zhu, Andrea Gazzo, Donna Wong, Zarina Yelskaya, Vikas Rai, Joshua Somar, ...> ;Journal of Clinical Oncology. 2023 Nov 20
2 citations
Associations Between Cancer Predisposition Mutations and Clonal Hematopoiesis in Patients With Solid Tumors.
Sebastià Franch-Expósito, Miika Mehine, Ryan N Ptashkin, Kelly L Bolton, Chaitanya Bandlamudi, Preethi Srinivasan, Linda Zhang, Margaret A Goodell, Erika Gedvilaite, K...> ;JCO Precision Oncology. 2023 Aug 1
Association of the CHEK2 c.1100delC variant, radiotherapy, and systemic treatment with contralateral breast cancer risk and breast cancer-specific survival.
Anna Morra, Maartje A C Schreurs, Irene L Andrulis, Hoda Anton-Culver, Annelie Augustinsson, Matthias W Beckmann, Sabine Behrens, Stig E Bojesen, Manjeet K Bolla, Hilt...> ;Cancer Medicine. 2023 Aug 1
11 citations
Genome-wide Association Study of Bladder Cancer Reveals New Biological and Translational Insights.
Stella Koutros, Lambertus A Kiemeney, Parichoy Pal Choudhury, Roger L Milne, Evangelina Lopez de Maturana, Yuanqing Ye, Vijai Joseph, Oscar Florez-Vargas, Lars Dyrskjø...> ;European Urology. 2023 Jul 1
Understanding the genetic complexity of puberty timing across the allele frequency spectrum.
Katherine A Kentistou, Lena R Kaisinger, Stasa Stankovic, Marc Vaudel, Edson M de Oliveira, Andrea Messina, Robin G Walters, Xiaoxi Liu, Alexander S Busch, Hannes Helg...> ;Medrxiv. 2023 Jun 20
3 citations
Germline drivers of gynecologic carcinosarcomas.
Tiffany Y Sia, Sushmita B Gordhandas, Ozge Birsoy, Yelena Kemel, Anna Maio, Erin Salo-Mullen, Margaret Sheehan, Martee L Hensley, Maria Rubinstein, Vicky Makker, Rache...> ;Gynecologic Oncology. 2023 Jul 1
Prevalence and Clinical Implications of Mismatch Repair-Proficient Colorectal Cancer in Patients With Lynch Syndrome.
Megha Ranganathan, Rosalba E Sacca, Magan Trottier, Anna Maio, Yelena Kemel, Erin Salo-Mullen, Amanda Catchings, Sarah Kane, Chiyun Wang, Vignesh Ravichandran, Ryan Pt...> ;JCO Precision Oncology. 2023 May 1
3 citations
Genome-wide analyses characterize shared heritability among cancers and identify novel cancer susceptibility regions.
Sara Lindström, Lu Wang, Helian Feng, Arunabha Majumdar, Sijia Huo, James Macdonald, Tabitha Harrison, Constance Turman, Hongjie Chen, Nicholas Mancuso, Theo Bammler, ...> ;Journal of the National Cancer Institute. 2023 Jun 8
1 citations
Author Correction: Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries.
Ceres Fernandez-Rozadilla, Maria Timofeeva, Zhishan Chen, Philip Law, Minta Thomas, Stephanie Schmit, Virginia Díez-Obrero, Li Hsu, Juan Fernandez-Tajes, Claire Palles...> ;Nature Genetics. 2023 Mar 1
Nucleotide excision repair deficiency is a targetable therapeutic vulnerability in clear cell renal cell carcinoma.
Aurel Prosz, Haohui Duan, Viktoria Tisza, Pranshu Sahgal, Sabine Topka, Gregory T Klus, Judit Börcsök, Zsofia Sztupinszki, Timothy Hanlon, Miklos Diossy, Laura Vizkele...> ;Biorxiv. 2023 Feb 7
4 citations
Comprehensive analysis of germline drivers in endometrial cancer.
Sushmita Gordhandas, Eric Rios-Doria, Karen A Cadoo, Amanda Catchings, Anna Maio, Yelena Kemel, Margaret Sheehan, Megha Ranganathan, Dina Green, Anjali Aryamvally, Ang...> ;Journal of the National Cancer Institute. 2023 May 8
3 citations
Aggregation tests identify new gene associations with breast cancer in populations with diverse ancestry.
Stefanie H Mueller, Alvina G Lai, Maria Valkovskaya, Kyriaki Michailidou, Manjeet K Bolla, Qin Wang, Joe Dennis, Michael Lush, Zomoruda Abu-Ful, Thomas U Ahearn, Irene...> ;Genome Medicine. 2023 Jan 26
8 citations
Expanded genetic testing of GIST patients identifies high proportion of non-syndromic patients with germline alterations.
Diana Mandelker, Antonio Marra, Nikita Mehta, Pier Selenica, Zarina Yelskaya, Ciyu Yang, Joshua Somar, Miika Mehine, Maksym Misyura, Olca Basturk, Alicia Latham, Maria...> ;NPJ Precision Oncology. 2023 Jan 2
33 citations
Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries.
Ceres Fernandez-Rozadilla, Maria Timofeeva, Zhishan Chen, Philip Law, Minta Thomas, Stephanie Schmit, Virginia Díez-Obrero, Li Hsu, Juan Fernandez-Tajes, Claire Palles...> ;Nature Genetics. 2023 Jan 1
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Journal Articles

Toward Automation of Germline Variant Curation in Clinical Cancer Genetics
Steven Lipkin, Karen Cadoo, Mark Robson, Kenneth Offit, Liying Zhang, Zsofia Stadler, Diana Mandelker, Nature
Development of Clinical Domain Working Groups for the Clinical Genome Resource (ClinGen): Lessons Learned and Plans for the Future
Heidi L Rehm, Ray E Hershberger, Meredith A Weaver, Birgit H Funke, Rong Mao, Kenneth Offit, William J Craigen, Sharon E Plon, Jonathan S Berg, Nature
The Genomics ADvISER: Development and Usability Testing of a Decision Aid for the Selection of Incidental Sequencing Results
Jada G Hamilton, Mark Robson, Kenneth Offit, Nature
Functional Mechanisms Underlying Pleiotropic Risk Alleles at the 19p13.1 Breast–Ovarian Cancer Susceptibility Locus
Susan M Domchek, Beth Y Karlan, Katherine L Nathanson, Kenneth Offit, Banu K Arun, Andrew Berchuck, Patricia A Ganz, Douglas A Levine, Nature
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Lectures

Genomics and Cancer Prevention
2013 Annual Meeting, Chicago, Illinois, USA
Genomics and Cancer Prevention
American Society of Clinical Oncology, 2013 Annual Meeting, Chicago, Illinois, USA

Press Mentions

Survivor’s Story Foreshadows One of Oncology’s Greatest SuccessesApril 14th, 2022
How Do Inherited Gene Mutations Cause Cancer? A New Database Will Help Researchers Find OutNovember 5th, 2021
Cancer Therapy Shapes the Fitness Landscape of Clonal HematopoiesisOctober 26th, 2020
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Hospital Affiliations

Memorial Sloan Kettering Cancer CenterNew York, New York

Insurance Accepted

Aetna Choice POS II
Aetna HMO
BCBS Blue Card PPO
CIGNA HMO
CIGNA Open Access
CIGNA PPO
Empire BCBS HMO
Empire BCBS PPO
First Health PPO
GHI PPO
Great West PPO
Multiplan PHCS PPO
Multiplan PPO
MVP Healthcare PPO
Oxford Health Freedom
Oxford Health Liberty
QualCare HMO
QualCare PPO
United Healthcare - Direct Choice Plus POS
United Healthcare - Direct Options PPO
Please verify your coverage with the provider's office directly when scheduling an appointment