KennethHShainMD

PubMed

• Health-related quality of life in transplant-eligible patients with newly diagnosed multiple myeloma treated with daratumumab, lenalidomide, bortezomib, and dexamethas...
  Rebecca Silbermann, Jacob Laubach, Jonathan L Kaufman, Douglas W Sborov, Brandi Reeves, Cesar Rodriguez, Ajai Chari, Luciano J Costa, Larry D Anderson Jr, Nitya Nathwa...> ;American Journal of Hematology. 2024 Apr 15
• The bone ecosystem facilitates multiple myeloma relapse and the evolution of heterogeneous drug resistant disease.
  Ryan T Bishop, Anna K Miller, Matthew Froid, Niveditha Nerlakanti, Tao Li, Jeremy S Frieling, Mostafa M Nasr, Karl J Nyman, Praneeth R Sudalagunta, Rafael R Canevarolo...> ;Nature Communications. 2024 Mar 19
• 2 citations
  Patient-Reported Outcomes among Multiple Myeloma Patients Treated with Standard of Care Idecabtagene Vicleucel.
  Castaneda Puglianini, O., Laura B Oswald, Lisa M Gudenkauf, Xiaoyin Li, Gabriel De Avila, Lauren C Peres, Kedar Kirtane, Brian D Gonzalez, Aasha I Hoogland, Oanh Nguye...> ;Cancers. 2023 Sep 25
• CK1δ and CK1ε Signaling Sustains Mitochondrial Metabolism and Cell Survival in Multiple Myeloma.
  Karen L Burger, Mario R Fernandez, Mark B Meads, Praneeth Sudalagunta, Paula S Oliveira, Rafael Renatino Canevarolo, Raghunandan Reddy Alugubelli, Alexandre Tungsevik,...> ;Cancer Research. 2023 Dec 1
• 2 citations
  Cardiac events after standard of care idecabtagene vicleucel for relapsed and refractory multiple myeloma.
  Castaneda Puglianini, O., Dae Hyun Lee, Abhishek Kumar, Turab Mohammed, Lauren C Peres, Melissa Alsina, Christina Bachmeier, Brandon J Blue, Jason Brayer, Sanjay Chand...> ;Blood Advances. 2023 Aug 22
• 13 citations
  Stem Cell Mobilization Yields with Daratumumab- and Lenalidomide-Containing Quadruplet Induction Therapy in Newly Diagnosed Multiple Myeloma: Findings from the MASTER ...
  Saurabh Chhabra, Natalie Callander, Nicole L Watts, Luciano J Costa, Bicky Thapa, Jonathan L Kaufman, Jacob Laubach, Douglas W Sborov, Brandi Reeves, Cesar Rodriguez, ...> ;Transplantation and Cellular Therapy. 2023 Mar 1
• 3 citations
  Replicative Instability Drives Cancer Progression.
  Benjamin B Morris, Jason P Smith, Qi Zhang, Zhijie Jiang, Oliver A Hampton, Michelle L Churchman, Susanne M Arnold, Dwight H Owen, Jhanelle E Gray, Patrick M Dillon, H...> ;Biomolecules. 2022 Oct 26
• 23 citations
  Early cytopenias and infections after standard of care idecabtagene vicleucel in relapsed or refractory multiple myeloma.
  Jennifer M Logue, Lauren C Peres, Hamza Hashmi, Christelle M Colin-Leitzinger, Alexandria M Shrewsbury, Hitomi Hosoya, Rebecca M Gonzalez, Christina Copponex, Krista H...> ;Blood Advances. 2022 Dec 27
• 1 citations
  Adding Cyclophosphamide to Bortezomib and Dexamethasone was not Associated With Improved Outcomes of Patients With Newly Diagnosed Light Chain Amyloidosis: A Retrospec...
  Yumeng Zhang, Lauren Duncanson, Jason Brayer, Frederic Reu, Doris Hansen, Melissa Alsina, Taiga Nishihori, Jose Ochoa-Bayona, Hien Liu, Kenneth Shain, Zachary Thompson...> ;Clinical Lymphoma, Myeloma & Leukemia. 2022 Aug 1
• 13 citations
  Racial and ethnic differences in clonal hematopoiesis, tumor markers, and outcomes of patients with multiple myeloma.
  Lauren C Peres, Christelle M Colin-Leitzinger, Mingxiang Teng, Julie Dutil, Raghunandan R Alugubelli, Gabriel DeAvila, Jamie K Teer, Dongliang Du, Qianxing Mo, Erin M ...> ;Blood Advances. 2022 Jun 28
• CancerCellTracker: a brightfield time-lapse microscopy framework for cancer drug sensitivity estimation.
  Qibing Jiang, Praneeth Sudalagunta, Maria C Silva, Rafael R Canevarolo, Xiaohong Zhao, Khandakar Tanvir Ahmed, Raghunandan Reddy Alugubelli, Gabriel DeAvila, Alexandre...> ;Bioinformatics. 2022 Aug 10
• 3 citations
  The Application of NextGen Sequencing in the Diagnosis of Myeloid Neoplasms in Myeloma Patients With Cytopenia.
  Jinming Song, Hailing Zhang, Ning Dong, Xiaohui Zhang, Mohammad Hussaini, Akriti Jain, Lynn Moscinski, Ken Shain, Rachid Baz, Melissa Alsina, Taiga Nishihori, Ling Zhang> ;Clinical Lymphoma, Myeloma & Leukemia. 2022 Jun 1
• 1 citations
  Leukoencephalopathy During Daratumumab-Based Therapy: A Case Series of Two Patients with Multiple Myeloma.
  Syeda Saba Kareem, Neena Viswanathan, Solmaz Sahebjam, Nam D Tran, Tyra Gatewood, Katherine Tobon, Rachid Baz, Yolanda Piña, Kenneth H Shain, Sepideh Mokhtari> ;Oncotargets and Therapy. 2022 Jan 1
• 72 citations
  NCCN Guidelines® Insights: Multiple Myeloma, Version 3.2022.
  Natalie S Callander, Muhamed Baljevic, Kehinde Adekola, Larry D Anderson, Erica Campagnaro, Jorge J Castillo, Caitlin Costello, Srinivas Devarakonda, Noura Elsedawy, M...> ;Journal of the National Comprehensive Cancer Network. 2022 Jan 1
• 9 citations
  Plasma cell dependence on histone/protein deacetylase 11 reveals a therapeutic target in multiple myeloma.
  A.G.M. Mostofa, Allison Distler, Mark B. Meads, Eva Sahakian, John Powers, Alexandra Achille, David Noyes, Gabriela Wright, Bin Fang, Victoria Izumi, John M. Koomen, R...> ;JCI Insight. 2021 Nov 18
• 10 citations
  IAP and HDAC inhibitors interact synergistically in myeloma cells through noncanonical NF-κB- and caspase-8-dependent mechanisms.
  Liang Zhou, Yu Zhang, Mark B. Meads, Yun Dai, Yanxia Ning, Xiaoyan Hu, Lin Li, Kanika Sharma, Jewel Nkwocha, Rebecca E. Parker, Danny Bui, Jacquelyn McCarter, Lora Kra...> ;Blood Advances. 2021 Oct 12
• 6 citations
  Assessment of Clonotypic Rearrangements and Minimal Residual Disease in Lymphoid Malignancies: A Large Cancer Center Experience Using clonoSEQ.
  Mohammad Hussaini, Jaya Srivastava, Lik Wee Lee, Taiga Nishihori, Bijal D. Shah, Melissa Alsina, Javier Pinilla-Ibarz, Kenneth H. Shain> ;Archives of Pathology & Laboratory Medicine. 2021 Aug 3
• 3 citations
  Response and resistance to CDK12 inhibition in aggressive B-cell lymphomas.
  Jing Gao, Michelle Wang, Yuan Ren, Tint Lwin, Tao Li, J. Yan, Eduardo M. Sotomayor, Derek R Duckett, Bijal D. Shah, Kenneth H. Shain, Xiaohong Zhao, Jianguo Tao> ;Haematologica. 2021 Jun 24
• 10 citations
  Therapeutic Targeting of Protein Disulfide Isomerase PDIA1 in Multiple Myeloma.
  Metis Hasipek, Dale Grabowski, Yihong Guan, Raghunandan Reddy Alugubelli, Anand D. Tiwari, Xiaorong Gu, Gabriel DeAvila, Ariosto S. Silva, Mark B. Meads, Yvonne Parker...> ;Cancers. 2021 May 28
• 10 citations
  Metabolic Changes Are Associated with Melphalan Resistance in Multiple Myeloma.
  David C. Koomen, Mark B. Meads, Dario M. Magaletti, Joy Guingab-Cagmat, Paula Oliveira, Bin Fang, Min Liu, Eric A. Welsh, Laurel E. Meke, Zhijie Jiang, Oliver A. Hampt...> ;Journal of Proteome Research. 2021 May 20
• 9 citations
  Transcriptional programming drives Ibrutinib-resistance evolution in mantle cell lymphoma
  Xiaohong Zhao, Michelle Wang, Huijuan Jiang, Tint Lwin, Paul M.C. Park, Jing Gao, Mark B. Meads, Yuan Ren, Tao Li, Jiao Sun, Naima Ahmed Fahmi, Satishkumar Singh, Lali...> ;Cell Reports. 2021 Mar 16
• 10 citations
  Host-derived Matrix Metalloproteinase-13 Activity Promotes Multiple Myeloma-induced Osteolysis and Reduces Overall Survival
  Chen Hao Lo, Gemma Shay, Jeremy J. McGuire, Tao Li, Kenneth H. Shain, Jun Yong Choi, Rita Fuerst, William R. Roush, Anna M. Knapinska, Gregg B. Fields, Conor C. Lynch> ;Cancer Research. 2021 Feb 1
• 4 citations
  MCL-1 dependency as a novel vulnerability for aggressive B cell lymphomas
  Michelle Wang, Tao Li, Yuan Ren, Bijal D. Shah, Tint Lwin, Jing Gao, Kenneth H. Shain, Wei Zhang, Xiaohong Zhao, Jianguo Tao> ;Blood Cancer Journal. 2021 Jan 14
• 151 citations
  Multiple myeloma, version 3.2021
  Shaji Kumar, Natalie S. Callander, Kehinde Adekola, Larry D. Anderson, Muhamed Baljevic, Erica L. Campagnaro, Jorge J. Castillo, Jason C. Chandler, Caitlin Costello, Y...> ;Journal of the National Comprehensive Cancer Network. 2020 Dec 2
• 344 citations
  Daratumumab, lenalidomide, bortezomib, and dexamethasone for transplant-eligible newly diagnosed multiple myeloma: the GRIFFIN trial
  Peter M. Voorhees, Jonathan L. Kaufman, Jacob P. Laubach, Douglas W. Sborov, Brandi Reeves, Cesar Rodriguez, Ajai Chari, Rebecca Silbermann, Luciano J. Costa, Larry D....> ;Blood. 2020 Aug 20
• Join now to see all

Abstracts/Posters

• Discovery of Novel IL3RA (CD123) Isoforms By Long Read Transcriptomics, Heterogeneous Expression Among AML Patient Cohorts and the Implications for Anti-CD123 Therapeu...
  Kenneth H. Shain, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Crowdsourced High-Risk Classifiers for Multiple Myeloma Patients Commonly Identify PHF19 As a Robust Progression Biomarker
  Kenneth H. Shain, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Composition of Immune Subpopulations Influence Multiple Myeloma Disease Progression
  Kenneth H. Shain, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Panobinostat As a Maintenance Therapy after Autologous Hematopoietic Cell Transplantation for Patients with Multiple Myeloma
  Kenneth H. Shain, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• The Result of a Phase 1 Study of Selinexor in Combination with High-Dose Melphalan and Autologous Hematopoietic Cell Transplantation for Multiple Myeloma
  Kenneth H. Shain, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• Depth of Response to Daratumumab (DARA), Lenalidomide, Bortezomib, and Dexamethasone (RVd) Improves over Time in Patients (pts) with Transplant-Eligible Newly Diagnose...
  Kenneth H. Shain, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Elotuzumab in Combination with an Immunomodulatory Agent (IMID) in Patients with Multiple Myeloma Refractory to Imids and/or Daratumumab: A Single-Institution Analysis...
  Kenneth H. Shain, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• Join now to see all

Lectures

• Pharmacodynamical Modeling of Two-Way Synergistic Effect for High-Throughput Drug Combination Screening in an Ex Vivo Reconstruction of Bone Marrow Using Primary Multi... 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018