KennethWWoodMD

PubMed

• Tales of how great drugs were brought down by a flawed rationale--letter.
  Tunquist BJ, Wood KW, Walker DH> ;Clin. Cancer Res.. 2013-03-01
• 345 citations
  Subtype and pathway specific responses to anticancer compounds in breast cancer.
  Laura M. Heiser, Anguraj Sadanandam, Wen-Lin Kuo, Stephen C. Benz, Theodore C. Goldstein, Sam Ng, William J. Gibb, Nicholas J. Wang, Safiyyah Ziyad, Frances Tong, Nora...> ;Proceedings of the National Academy of Sciences of the United States of America. 2012 Feb 21
• 162 citations
  Antitumor activity of an allosteric inhibitor of centromere-associated protein-E
  Kenneth Wood, Latesh Lad, Lusong Luo, Xiangping Qian, Steven D. Knight, Neysa Nevins, Katjuša Brejc, David Sutton, Aidan G. Gilmartin, Penelope Chua, Radhika Desai, St...> ;Proceedings of the National Academy of Sciences of the United States of America. 2010 Mar 30
• 60 citations
  Activity of the Kinesin Spindle Protein Inhibitor Ispinesib (SB-715992) in Models of Breast Cancer
  James W. Purcell, Jefferson Davis, Mamatha Reddy, Shamra Martin, Kimberly Samayoa, Hung Vo, Karen Thomsen, Peter Bean, Wen Lin Kuo, Safiyyah Ziyad, Jessica Billig, Hei...> ;Clinical Cancer Research. 2010 Jan 15
• 15 citations
  Kinetic analysis of Mad2-Cdc20 formation: conformational changes in Mad2 are catalyzed by a C-Mad2-ligand complex.
  Latesh Lad, Serge Lichtsteiner, James J. Hartman, Kenneth Wood, Roman Sakowicz> ;Biochemistry. 2009 Oct 13
• 37 citations
  Centromere-Associated Protein E: A Motor That Puts the Brakes on the Mitotic Checkpoint
  Kenneth W. Wood, Penelope Chua, David Sutton, Jeffrey R. Jackson> ;Clinical Cancer Research. 2008 Dec 1
• 87 citations
  Mechanism of inhibition of human KSP by ispinesib.
  Latesh Lad, Lusong Luo, Jeffrey D. Carson, Kenneth W. Wood, James J. Hartman, Robert A. Copeland, Roman Sakowicz> ;Biochemistry. 2008 Feb 22
• Coupling of protein and hydration-water dynamics in biological membranes.
  Wood K, Plazanet M, Gabel F, Kessler B, Oesterhelt D, Tobias DJ, Zaccai G, Weik M> ;Proc. Natl. Acad. Sci. U.S.A.. 2007-11-13
• 85 citations
  ATP-competitive inhibitors of the mitotic kinesin KSP that function via an allosteric mechanism.
  Lusong Luo, Cynthia A. Parrish, Neysa Nevins, Dean E. McNulty, Amita M. Chaudhari, Jeffery D Carson, Valery Sudakin, Antony N. Shaw, Ruth Lehr, Huizhen Zhao, Sharon Sw...> ;Nature Chemical Biology. 2007 Nov 1
• 56 citations
  Novel ATP-competitive kinesin spindle protein inhibitors.
  Cynthia A. Parrish, Nicholas D. Adams, Kurt R. Auger, Joelle Lorraine Burgess, Jeffrey D. Carson, Amita M. Chaudhari, Robert A. Copeland, Melody Diamond, Carla A. Dona...> ;Journal of Medicinal Chemistry. 2007 Aug 29
• 106 citations
  Differential regulation of WASP and N-WASP by Cdc42, Rac1, Nck, and PI(4,5)P2.
  Nenad Tomasevic, Zhiheng Jia, Alan J. Russell, Toby Fujii, James J. Hartman, Sheila Clancy, Manping Wang, Christophe Beraud, Kenneth W. Wood, Roman Sakowicz> ;Biochemistry. 2007 Feb 16
• 202 citations
  Antitumor Activity of a Kinesin Inhibitor
  Roman Sakowicz, Jeffrey T. Finer, Christophe Beraud, Anne M. Crompton, Evan R. Lewis, Alex Fritsch, Yan Lee, John Mak, Robert Moody, Rebecca Turincio, John C. Chabala,...> ;Cancer Research. 2004 May 1
• The FOXP1 winged helix transcription factor is a novel candidate tumor suppressor gene on chromosome 3p.
  Banham AH, Beasley N, Campo E, Fernandez PL, Fidler C, Gatter K, Jones M, Mason DY, Prime JE, Trougouboff P, Wood K, Cordell JL> ;Cancer Res.. 2001-12-15
• 50 citations
  CENP-E is an essential kinetochore motor in maturing oocytes and is masked during Mos-dependent, cell cycle arrest at metaphase II
  Nicholas S. Duesbery, Taesaeng Choi, Kevin D. Brown, Kenneth Wood, James H. Resau, Kenji Fukasawa, Don W. Cleveland, George F. Vande Woude> ;Proceedings of the National Academy of Sciences of the United States of America. 1997 Aug 19
• 150 citations
  The cytoplasmic raf oncogene induces a neuronal phenotype in PC12 cells: a potential role for cellular raf kinases in neuronal growth factor signal transduction
  Kenneth Wood, Haiqing Qi, Gabriella D'Arcangelo, Robert C. Armstrong, Thomas M. Roberts, Simon Halegoua> ;Proceedings of the National Academy of Sciences of the United States of America. 1993 Jun 1
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