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Kevin Ho, MD, Nephrology, North Waltham, MA

KevinHoMD

Nephrology North Waltham, MA

Acute Renal Failure, Chronic Renal Failure & Dialysis, Hereditary Kidney Disease Genetics

VP of Medical Support, Global Medical Office, In Center Hemodialysis, Quality & Regulatory

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Summary

  • In nephrology, Dr. Ho identified defining member, ROMK1 (Kir1.1), of the overall inward rectifier potassium channel family (Kir). ROMK channels are the primary mechanism for renal potassium secretion, the basis for aldosterone-regulated potassium homeostasis. His ROMK1 model presented in '92 at Oxford demonstrated conservation of the potassium channel pore among structurally different potassium channel families. Research at Washington Univ focused on molecular basis for Kir channel assembly. Joining Univ of Pittsburgh in '02, his projects included study of cardiovascular ABCC9 genetic variants associated with early Type 1 diabetic CKD. He served as medical director for several dialysis units including UPMC Dialysis Services Network, Fabry disease nephrology consultant for the Lysosomal Storage Disease group, and organizer of Bone Works group focused on Kidney-Bone axis. As a Dept of Med Quality Council member, he led projects exploring transitions-of-care in chronic kidney disease and ESRD for inpatients developing AKI requiring dialysis, vascular access planning, and computer-assisted individualized dosing of erythropoiesis stimulating agents. He served on the PA Renal Disease Advisory Cmte, Board of Dirs for National Kidney Foundation serving the Alleghenies, and Renal Network Medical Review Board for PA and DE. Subsequently at Geisinger as a clinician-scientist, he developed electronic health record-based phenotypic algorithms (acute kidney injury, polycystic ovary syndrome contributing to type 2 diabetes, obesity, early CKD) for predictive analytics and integration with EHR in real-time and with genomic data (MyCode, eMERGE) for phenotype-genotype analyses. He served as Fabry Registry PI and CKDGen Consortium site PI and writing group member. He transitioned to industry as a Medical Director, U.S. Medical Affairs in Rare Diseases at Sanofi Genzyme. He is currently VP of Medical Support, Global Medical Office at Fresenius Medical Care North America.

Education & Training

  • Brigham and Women's Hospital/Massachusetts General Hospital
    Brigham and Women's Hospital/Massachusetts General HospitalFellowship, Nephrology, 1990 - 1994
  • New York Presbyterian Hospital (Columbia Campus)
    New York Presbyterian Hospital (Columbia Campus)Residency, Internal Medicine, 1987 - 1990
  • Columbia University Vagelos College of Physicians and Surgeons
    Columbia University Vagelos College of Physicians and SurgeonsClass of 1987
  • Harvard University
    Harvard UniversityA.B., Biological Sciences, 1978 - 1982

Certifications & Licensure

  • PA State Medical License
    PA State Medical License 2002 - 2024

Awards, Honors, & Recognition

  • Top Patient Experience Clinician Award Geisinger Health System, 2017
  • Faculty Honoree, Honors Convocation University of Pittsburgh, 228th Anniversary, 2015
  • The Gift of Life Medical Award National Kidney Foundation, 2014
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Publications & Presentations

PubMed

Journal Articles

  • Variants in STAU2 associate with metformin response in a type 2 diabetes cohort: a pharmacogenomics study using real-world electronic health record data  
    Yanfei Zhang, Ying Hu, Kevin Ho, Dustin N Hartzel, Vida Abedi, Ramin Zand, Marc S Williams, Ming Ta M Lee., MedRxiv. doi: https://doi.org/10.1101/2020.03.18.20037218, 3/18/2020

Books/Book Chapters

Abstracts/Posters

  • Cardiovascular gene ABCC9 is associated with Type 1 diabetic nephropathy
    Ho K, Chang Y-F, Ferrell RE, Lawrence E, Fried L, Liu W, Kim SI, Choi M, Orchard TJ, J Amer Soc Nephrol 2005;16: 589A, American Society of Nephrology, https://app.box.com/s/ohb71285bc2vwxihn4ap, 11/2005
  • Regulatory elements in the sulphonylurea receptor 2 gene promoter
    Ho K, Liu W, J. Am. Soc. Nephrol. 2007;18 Suppl.: 607A, P-097, American Society of Nephrology, https://app.box.com/s/hjrl0y4sp0wl4oaldw1i, 11/2007
  • Low renal recovery in inpatients starting hemodialysis and transitioning to outpatient dialysis: Prior chronic kidney disease and vascular access planning
    Andersen SL, Chang YF, Seddon PA, Martin SC, Ho K, J. Am. Soc. Nephrol. 2011;22: 788A, P-2914, American Society of Nephrology, https://app.box.com/s/8ql3m4rmg7ncwobek7o5, 11/2011
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Lectures

  • Plenary Talk -- Update on Chronic Kidney Disease Symposium: CKD Global Trends – Past, Present & Future 
    Penn State College of Medicine, The Kidney Foundation of Central PA, Hershey, PA - 4/16/2019
  • Nephrology for Internists/Hospitalists Symposium: Hospital-associated acute kidney injury 
    Geisinger Medical Center, Danville, PA - 4/12/2019
  • Grand Rounds: Transforming acute kidney injury in the age of electronic health records 
    Division of Nephrology, University of Maryland, Baltimore, MD - 1/28/2019

Committees

  • Steering Committee and discussion group moderator, American Kidney Fund's 2020 "Unknown Causes of Kidney Disease Summit" 2020 - 2020
  • Member, Vascular Access Advisory Panel, Quality Insights Renal Network 4 (PA, DE) 2014 - 2014
  • Member, Medical Review Board, Quality Insights Renal Network 4 (PA, DE) 2013 - 2014
  • Member, Acute Kidney Injury Group, Critical Care Medicine-CRISMA (Clinical Research, Investigation, Systems Modeling of Acute Illness) Center 2012 - 2014
  • Member, Advisory Group Center for Assistance in Research using eRecord (CARe) 2012 - 2014
  • Member, Medical Review Board, ESRD Network 4 (PA, DE) of The Renal Network, Inc. 2012 - 2013
  • Member, The Renal Network Vascular Access Advisory Panel (ESRD Networks 4, 9, 10 for PA, DE, IL, IN, KY, OH) 2012 - 2013
  • Member, Department of Medicine Quality Council 2011 - 2014
  • Member, Board of Directors, National Kidney Foundation Serving the Alleghenies 2009 - 2012
  • Member, Renal Disease Advisory Committee, Commonwealth of Pennsylvania 2007 - 2011

Professional Memberships