KevinK.LeungMD

PubMed

• 68 citations
  Engineering luminescent biosensors for point-of-care SARS-CoV-2 antibody detection.
  , , , , , , , , , , , , , , , , , > ;Nature Biotechnology. 2021 Mar 25
• 6 citations
  Large remodeling of the Myc-induced cell surface proteome in B cells and prostate cells creates new opportunities for immunotherapy.
  Wentao Chen, Kurt Yun Mou, Paige Solomon, Rahul Aggarwal, Kevin Leung, James A. Wells> ;Proceedings of the National Academy of Sciences of the United States of America. 2021 Jan 26
• 62 citations
  Bi-paratopic and multivalent VH domains block ACE2 binding and neutralize SARS-CoV-2.
  Colton J Bracken, Shion A. Lim, Paige Solomon, Nicholas J. Rettko, Duy P. Nguyen, Beth S. Zha, Kaitlin Schaefer, James Byrnes, Jie Zhou, Irene Lui, Jia Liu, Katarina P...> ;Nature Chemical Biology. 2021 Jan 1
• 18 citations
  Bispecific VH/Fab antibodies targeting neutralizing and non-neutralizing Spike epitopes demonstrate enhanced potency against SARS-CoV-2.
  Shion A. Lim, Josef A. Gramespacher, Katarina Pance, Nicholas J. Rettko, Paige Solomon, Jing Jin, Irene Lui, Susanna K. Elledge, Jia Liu, Colton J Bracken, Graham Simm...> ;Mabs. 2021 Jan 1
• 33 citations
  Precision engineering of an anti-HLA-A2 chimeric antigen receptor in regulatory T cells for transplant immune tolerance
  Yannick D. Muller, Leonardo M. R. Ferreira, Emilie Ronin, Patrick Ho, Vinh Nguyen, Gaetano Faleo, Yu Zhou, Karim Lee, Kevin Leung, Nikolaos Skartsis, Anupurna M. Kaul,...> ;Frontiers in Immunology. 2021 Jan 1
• 139 citations
  Engineered ACE2 receptor traps potently neutralize SARS-CoV-2.
  Anum A. Glasgow, Jeff E. Glasgow, Daniel Limonta, Paige Solomon, Irene Lui, Yang Zhang, Matthew A. Nix, Nicholas J. Rettko, Shoshana Zha, Rachel Yamin, Kevin Kao, Oren...> ;Proceedings of the National Academy of Sciences of the United States of America. 2020 Nov 10
• 24 citations
  Deep profiling of protease substrate specificity enabled by dual random and scanned human proteome substrate phage libraries
  Jie Zhou, Shantao Li, Kevin Leung, Brian O'Donovan, James Zou, Joseph L. DeRisi, James A. Wells> ;Proceedings of the National Academy of Sciences of the United States of America. 2020 Oct 13
• 44 citations
  Competitive SARS-CoV-2 Serology Reveals Most Antibodies Targeting the Spike Receptor-Binding Domain Compete for ACE2 Binding.
  James Byrnes, Xin X. Zhou, Irene Lui, Susanna K. Elledge, Jeff E. Glasgow, Shion A. Lim, Rita P. Loudermilk, Charles Y. Chiu, Taia T. Wang, Michael R. Wilson, Kevin Le...> ;Msphere. 2020 Sep 16
• 5 citations
  Targeting Phosphotyrosine in Native Proteins with Conditional, Bispecific Antibody Traps.
  Xin X. Zhou, Colton J Bracken, Kaihua Zhang, Jie Zhou, Yun Mou, Lei Wang, Yifan Cheng, Kevin Leung, James A. Wells> ;Journal of the American Chemical Society. 2020 Sep 14
• 32 citations
  Engineering luminescent biosensors for point-of-care SARS-CoV-2 antibody detection.
  , , , , , , , , , , , , , , , , , > ;Medrxiv. 2020 Aug 21
• 4 citations
  Bi-paratopic and multivalent human VH domains neutralize SARS-CoV-2 by targeting distinct epitopes within the ACE2 binding interface of Spike
  Colton J Bracken, Shion A. Lim, Paige Solomon, Nicholas J. Rettko, Duy P. Nguyen, Beth S. Zha, Kaitlin Schaefer, James Byrnes, Jie Zhou, Irene Lui, Jia Liu, Katarina P...> ;Biorxiv. 2020 Aug 10
• 51 citations
  Engineered ACE2 receptor traps potently neutralize SARS-CoV-2.
  Anum A. Glasgow, Jeff E. Glasgow, Daniel Limonta, Paige Solomon, Irene Lui, Yang Zhang, Matthew A. Nix, Nicholas J. Rettko, Shion A. Lim, Shoshana Zha, Rachel Yamin, K...> ;Biorxiv. 2020 Aug 1
• 78 citations
  Prediction of total knee replacement and diagnosis of osteoarthritis by using deep learning on knee radiographs: Data from the osteoarthritis initiative
  Kevin Leung, Bofei Zhang, Jimin Tan, Yiqiu Shen, Krzysztof J. Geras, James S. Babb, Kyunghyun Cho, Gregory Chang, Cem M. Deniz> ;Radiology. 2020 Jun 23
• 12 citations
  A SARS-CoV-2 serological assay to determine the presence of blocking antibodies that compete for human ACE2 binding
  James Byrnes, Xin X. Zhou, Irene Lui, Susanna K. Elledge, Jeff E. Glasgow, Shion A. Lim, Rita P. Loudermilk, Charles Y. Chiu, Michael R. Wilson, Kevin Leung, James A. ...> ;Medrxiv. 2020 May 29
• 17 citations
  Theranostic Targeting of CUB Domain Containing Protein 1 (CDCP1) in Pancreatic Cancer
  Anna Moroz, Yung-hua Wang, Jeremy Sharib, Junnian Wei, Ning Zhao, Yangjie Huang, Zhuo Chen, Alexander J. Martinko, Jie Zhuo, Shion A. Lim, Lydia H. Zhang, Youngho Seo,...> ;Clinical Cancer Research. 2020 Apr 27
• 51 citations
  Broad and thematic remodeling of the surfaceome and glycoproteome on isogenic cells transformed with driving proliferative oncogenes.
  Kevin Leung, Gary M. Wilson, Lisa L. Kirkemo, Nicholas M. Riley, Joshua J. Coon, James A. Wells> ;Proceedings of the National Academy of Sciences of the United States of America. 2020 Mar 23
• 41 citations
  Multiomics of azacitidine-treated AML cells reveals variable and convergent targets that remodel the cell-surface proteome.
  Kevin Leung, Aaron N. Nguyen, Tao Shi, Lin Tang, Xiaochun Ni, Laure Escoubet, Kyle J. MacBeth, Jorge DiMartino, James A. Wells> ;Proceedings of the National Academy of Sciences of the United States of America. 2019 Jan 8
• 15 citations
  Binding of DNA-Intercalating Agents to Oxidized and Reduced Quinone Reductase 2
  Kevin Leung, Brian H. Shilton> ;Biochemistry. 2015 Dec 14
• 20 citations
  Quinone Reductase 2 Is an Adventitious Target of Protein Kinase CK2 Inhibitors TBBz (TBI) and DMAT
  Kevin Leung, Brian H. Shilton> ;Biochemistry. 2015 Jan 13
• 27 citations
  Chloroquine Binding Reveals Flavin Redox Switch Function of Quinone Reductase 2
  Kevin Leung, Brian H. Shilton> ;The Journal of Biological Chemistry. 2013 Apr 19
• 7 citations
  Hydration structures of U(III) and U(IV) ions from ab initio molecular dynamics simulations.
  Kevin Leung, Tina M. Nenoff> ;The Journal of Chemical Physics. 2012 Aug 21
• 13 citations
  Predicting the acidity constant of a goethite hydroxyl group from first principles
  Kevin Leung, Louise J. Criscenti> ;Journal of Physics. Condensed Matter. 2012 Mar 28
• 9 citations
  Flavin adenine dinucleotide content of quinone reductase 2: analysis and optimization for structure-function studies.
  Kevin Leung, David W. Litchfield, Brian H. Shilton> ;Analytical Biochemistry. 2012 Jan 1
• Using atomic layer deposition to hinder solvent decomposition in lithium ion batteries: first-principles modeling and experimental studies.
  Leung, K.,Qi, Y.,Zavadil, K. R.,Jung, Y. S.,Dillon, A. C.,Cavanagh, A. S.,Lee, S. H.,George, S. M.> ;J. Am. Chem. Soc.. 2011 Jul 30
• Ab initio molecular dynamics simulations of the initial stages of solid-electrolyte interphase formation on lithium ion battery graphitic anodes.
  Leung, K.,Budzien, J. L.> ;Phys Chem Chem Phys. 2010 May 27
• Join now to see all