KhaledAzizMDPhD

PubMed

• 1 citations
  Tumor volume as a predictor of cell free DNA mutation detection in advanced non-small cell lung cancer.
  Justin M Haseltine, Michael Offin, Jessica R Flynn, Zhigang Zhang, Emily S Lebow, Khaled Aziz, Alex Makhnin, Jordan Eichholz, Lee P Lim, Mark Li, James M Isbell, Danie...> ;Translational Lung Cancer Research. 2022 Aug 1
• 29 citations
  Single-Dose Intraventricular Nimodipine Microparticles Versus Oral Nimodipine for Aneurysmal Subarachnoid Hemorrhage.
  Andrew P. Carlson, Daniel Hänggi, George K.C. Wong, Nima Etminan, Stephan A. Mayer, Francois Aldrich, Michael N. Diringer, Erich Schmutzhard, Herbert J. Faleck, David ...> ;Stroke. 2020 Apr 1
• 98 citations
  The AMPK-Parkin axis negatively regulates necroptosis and tumorigenesis by inhibiting the necrosome.
  Seung Baek Lee, Jung Jin Kim, Sang Ah Han, Yingfang Fan, Li Sha Guo, Khaled Aziz, Somaira Nowsheen, Sung Sun Kim, Seon-Young Park, Qifeng Luo, Jin Ook Chung, Sung Il C...> ;Nature Cell Biology. 2019 Jul 29
• 39 citations
  Ccne1 Overexpression Causes Chromosome Instability in Liver Cells and Liver Tumor Development in Mice
  Khaled Aziz, Jazeel F. Limzerwala, Ines Sturmlechner, Erin Hurley, Cheng Zhang, Karthik B. Jeganathan, Grace G. Nelson, Steve F. Bronk, Raul O. Fierro Velasco, Erik Ja...> ;Gastroenterology. 2019 Jul 1
• 32 citations
  Trastuzumab in Female Breast Cancer Patients With Reduced Left Ventricular Ejection Fraction
  Somaira Nowsheen, Khaled Aziz, Jae Yoon Park, Amir Lerman, Hector R. Villarraga, Kathryn J. Ruddy, Joerg Herrmann> ;Journal of the American Heart Association. 2018 Aug 7
• 12 citations
  Mosaic-variegated aneuploidy syndrome mutation or haploinsufficiency in Cep57 impairs tumor suppression
  Khaled Aziz, Cynthia J. Sieben, Karthik B. Jeganathan, Masakazu Hamada, Brian A. Davies, Raul O. Fierro Velasco, Nazneen Rahman, David J. Katzmann, Jan M. van Deursen> ;The Journal of Clinical Investigation. 2018 Aug 1
• 15 citations
  ZNF506-dependent positive feedback loop regulates H2AX signaling after DNA damage.
  Somaira Nowsheen, Khaled Aziz, Kuntian Luo, Min Deng, Bo Qin, Jian Yuan, Karthik B. Jeganathan, Jia Yu, Henan Zhang, Wei Ding, Jan M. van Deursen, Zhenkun Lou> ;Nature Communications. 2018 Jul 16
• 71 citations
  L3MBTL2 orchestrates ubiquitin signalling by dictating the sequential recruitment of RNF8 and RNF168 after DNA damage
  Somaira Nowsheen, Khaled Aziz, Asef Aziz, Min Deng, Bo Qin, Kuntian Luo, Karthikbabu B Jeganathan, Henan Zhang, Tongzheng Liu, Jia Yu, Yibin Deng, Jian Yuan, Wei Ding,...> ;Nature Cell Biology. 2018 Mar 26
• 96 citations
  Complex DNA Damage: A Route to Radiation-Induced Genomic Instability and Carcinogenesis
  Ifigeneia V. Mavragani, Zacharenia Nikitaki, Maria P Souli, Asef Aziz, Somaira Nowsheen, Khaled Aziz, Emmy P. Rogakou, Alexandros G. Georgakilas> ;Cancers. 2017 Jul 18
• 148 citations
  Targeting DDX3 with a small molecule inhibitor for lung cancer therapy
  Guus M. Bol, Farhad Vesuna, Min Xie, Jing Zeng, Khaled Aziz, Nishant Gandhi, Anne Levine, Ashley Irving, Dorian Korz, Saritha Tantravedi, Marise R. Heerma van Voss, Ka...> ;EMBO Molecular Medicine. 2015 May 1
• 144 citations
  Twist1-induced dissemination preserves epithelial identity and requires E-cadherin
  Eliah R. Shamir, Elisa Pappalardo, Danielle M. Jorgens, Kester Coutinho, Wen-Ting K Tsai, Khaled Aziz, Manfred Auer, Phuoc T. Tran, Joel S. Bader, Andrew J. Ewald> ;The Journal of Cell Biology. 2014 Mar 3
• 26 citations
  Epigenetic inactivation of DNA repair in breast cancer.
  Somaira Nowsheen, Khaled Aziz, Phuoc T. Tran, Vassilis G. Gorgoulis, Eddy S. Yang, Alexandros G. Georgakilas> ;Cancer Letters. 2014 Jan 28
• 56 citations
  The Twist box domain is required for Twist1-induced prostate cancer metastasis
  Rajendra P. Gajula, Sivarajan T. Chettiar, Russell Williams, Saravanan Thiyagarajan, Yoshinori Kato, Khaled Aziz, Ruoqi Wang, Nishant Gandhi, Aaron T. Wild, Farhad Ves...> ;Molecular Cancer Research. 2013 Nov 1
• 98 citations
  Toxicity and adverse effects of Tamoxifen and other anti-estrogen drugs.
  Geniey Yang, Somaira Nowsheen, Khaled Aziz, Alexandros G. Georgakilas> ;Pharmacology & Therapeutics. 2013 Sep 1
• 31 citations
  Concurrent versus Sequential Sorafenib Therapy in Combination with Radiation for Hepatocellular Carcinoma
  Aaron T. Wild, Nishant Gandhi, Sivarajan T. Chettiar, Khaled Aziz, Rajendra P. Gajula, Russell Williams, Rachit Kumar, Kekoa Taparra, Jing Zeng, Jessica Cades, Esteban...> ;Plos One. 2013 Jun 6
• 32 citations
  Hedgehog Pathway Inhibition Radiosensitizes Non-Small Cell Lung Cancers
  Jing Zeng, Khaled Aziz, Sivarajan T. Chettiar, Blake T. Aftab, Michael Armour, Rajendra P. Gajula, Nishant Gandhi, T. Salih, Joseph M. Herman, John Wong, Charles M. Ru...> ;International Journal of Radiation Oncology, Biology, Physics. 2013 May 1
• 45 citations
  Inhibition of TWIST1 Leads to Activation of Oncogene-Induced Senescence in Oncogene Driven Non-Small Cell Lung Cancer
  Timothy F. Burns, Irina Dobromilskaya, Sara C. Murphy, Rajendra P. Gajula, Saravanan Thiyagarajan, Sarah N. Chatley, Khaled Aziz, Yoon Jae Cho, Phuoc T. Tran, Charles ...> ;Molecular Cancer Research. 2013 Apr 1
• 36 citations
  Novel Hsp90 inhibitor NVP-AUY922 radiosensitizes prostate cancer cells
  Nishant Gandhi, Aaron T. Wild, Sivarajan T. Chettiar, Khaled Aziz, Yoshinori Kato, Rajendra P. Gajula, Russell Williams, Jessica Cades, Anvesh Annadanam, Danny Y. Song...> ;Cancer Biology & Therapy. 2013 Jan 28
• 29 citations
  Molecular markers for cancer prognosis and treatment: have we struck gold?
  Somaira Nowsheen, Khaled Aziz, Mihalis I. Panayiotidis, Alexandros G. Georgakilas> ;Cancer Letters. 2012 Dec 31
• 80 citations
  Twist1 suppresses senescence programs and thereby accelerates and maintains mutant Kras-induced lung tumorigenesis.
  Phuoc T. Tran, Emelyn H. Shroff, Timothy F. Burns, Saravanan Thiyagarajan, Sandhya Das, Tahera Zabuawala, Joy Chen, Yoon Jae Cho, Richard Luong, Pablo Tamayo, T. Salih...> ;Plos Genetics. 2012 May 24
• 24 citations
  Nelfinavir induces radiation sensitization in pituitary adenoma cells.
  Jing Zeng, Alfred P. See, Khaled Aziz, Saravanan Thiyagarajan, T. Salih, Rajendra P. Gajula, Michael Armour, Jillian Phallen, Stephanie A. Terezakis, Lawrence Kleinber...> ;Cancer Biology & Therapy. 2011 Oct 1
• 24 citations
  Hypothermia postpones DNA damage repair in irradiated cells and protects against cell killing
  Brandon J. Baird, Jennifer S. Dickey, Asako J. Nakamura, Christophe E. Redon, Palak R. Parekh, Yuri Griko, Khaled Aziz, Alexandros G. Georgakilas, William M. Bonner, O...> ;Mutation Research. 2011 Jun 3
• 54 citations
  DNA-PKcs deficiency leads to persistence of oxidatively induced clustered DNA lesions in human tumor cells
  Prakash Peddi, Charles W. Loftin, Jennifer S. Dickey, Jessica M. Hair, Kara J. Burns, Khaled Aziz, Dave C. Francisco, Mihalis I. Panayiotidis, Olga A. Sedelnikova, Wil...> ;Free Radical Biology & Medicine. 2010 May 15
• 11 citations
  BRCA1 involvement in toxicological responses and human cancer etiology.
  Alexandros G. Georgakilas, Khaled Aziz, Dominique Ziech, Stavroula Georgakila, Mihalis I. Panayiotidis> ;Toxicology Letters. 2009 Jul 24
• 62 citations
  Accumulation of oxidatively induced clustered DNA lesions in human tumor tissues.
  Somaira Nowsheen, Rebecca L. Wukovich, Khaled Aziz, Peter T. Kalogerinis, Christopher C. Richardson, Mihalis I. Panayiotidis, William M. Bonner, Olga A. Sedelnikova, A...> ;Mutation Research. 2009 Mar 31
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