KimberlyLeslieMD

PubMed

• Global expression analysis of endometrial cancer cells in response to progesterone identifies new therapeutic targets.
  Thiel, K., Newtson, A., Devor, E., Zhang, Y., Malmrose, P., Bi, J., Losh, H., Davies, S., Smith, L., Padilla, J., Leiva, S., Grueter, C., Breheny, P., Hagan, C., Pufal...> ;The Journal of Steroid Biochemistry and Molecular Biology. 2023 Nov 1
• 1 citations
  FGFR2 mutations promote endometrial cancer progression through dual engagement of EGFR and Notch signalling pathways.
  Garima Dixit, Jesus Gonzalez-Bosquet, Joseph Skurski, Eric J Devor, Erin B Dickerson, Warren B Nothnick, Priya D Issuree, Kimberly K Leslie, Thorsten Maretzky> ;Clinical and Translational Medicine. 2023 May 1
• Utilizing an Endogenous Progesterone Receptor Reporter Gene for Drug Screening and Mechanistic Study in Endometrial Cancer.
  Yiyang Li, Wei Zhou, Xiangbing Meng, Sarina D Murray, Long Li, Abby Fronk, Vanessa J Lazaro-Camp, Kuo-Kuang Wen, Meng Wu, Adam Dupuy, Kimberly K Leslie, Shujie Yang> ;Cancers. 2022 Oct 6
• 16 citations
  Sequencing and p53 Immunohistochemistry Predict Outcomes When Bevacizumab Is Added to Frontline Chemotherapy in Endometrial Cancer: An NRG Oncology/Gynecologic Oncolog...
  Kristina W Thiel, Eric J Devor, Virginia L Filiaci, David Mutch, Katherine Moxley, Angeles Alvarez Secord, Krishnansu S Tewari, Megan E McDonald, Cara Mathews, Casey C...> ;Journal of Clinical Oncology. 2022 Oct 1
• 9 citations
  Blocking autophagy overcomes resistance to dual histone deacetylase and proteasome inhibition in gynecologic cancer.
  Jianling Bi, Yuping Zhang, Paige K Malmrose, Haley A Losh, Andreea M Newtson, Eric J Devor, Kristina W Thiel, Kimberly K Leslie> ;Cell Death & Disease. 2022 Jan 17
• 2 citations
  Enhancing progestin therapy via HDAC inhibitors in endometrial cancer.
  Yiyang Li, Wei Zhou, Long Li, John W Li, Tianyue Li, Cheng Huang, Vanessa J Lazaro-Camp, Tamar Kavlashvili, Yuping Zhang, Henry Reyes, Yujun Li, Donghai Dai, William Z...> ;American Journal of Cancer Research. 2022 Jan 1
• 4 citations
  The Synthetic Curcumin Analog HO-3867 Rescues Suppression of PLAC1 Expression in Ovarian Cancer Cells.
  Eric J. Devor, Brandon M. Schickling, Jace R. Lapierre, David Bender, Jesus Gonzalez-Bosquet, Kimberly K. Leslie> ;Pharmaceuticals. 2021 Sep 21
• 27 citations
  Successful Patient-Derived Organoid Culture of Gynecologic Cancers for Disease Modeling and Drug Sensitivity Testing.
  Jianling Bi, A.M. Newtson, Yuping Zhang, Eric J. Devor, Megan I. Samuelson, Kristina W. Thiel, Kimberly K. Leslie> ;Cancers. 2021 Jun 10
• 1 citations
  Team Science: American Heart Association's Hypertension Strategically Focused Research Network Experience
  Mark K. Santillan, Richard C. Becker, David A. Calhoun, Allen W. Cowley, Joseph T. Flynn, Justin L. Grobe, Theodore A. Kotchen, Daniel T. Lackland, Kimberly K. Leslie,...> ;Hypertension. 2021 May 3
• 7 citations
  A Surgical Window Trial Evaluating Medroxyprogesterone Acetate with or without Entinostat in Patients with Endometrial Cancer and Validation of Biomarkers of Cellular ...
  Linda R. Duska, Virginia L. Filiaci, Joan L. Walker, Laura L. Holman, Emily K. Hill, Richard G. Moore, Kari L. Ring, Michael L. Pearl, Carolyn Y. Muller, Christina L. ...> ;Clinical Cancer Research. 2021 May 15
• 13 citations
  Creation and validation of models to predict response to primary treatment in serous ovarian cancer.
  Jesus Gonzalez Bosquet, Eric J. Devor, Andreea M. Newtson, Brian J. Smith, David Bender, Michael J. Goodheart, Megan E McDonald, Terry A. Braun, Kristina W. Thiel, Kim...> ;Scientific Reports. 2021 Mar 16
• 7 citations
  Bacterial, Archaea, and Viral Transcripts (BAVT) Expression in Gynecological Cancers and Correlation with Regulatory Regions of the Genome
  Jesus Gonzalez-Bosquet, Silvana Pedra-Nobre, Eric J. Devor, Kristina W. Thiel, Michael J. Goodheart, David Bender, Kimberly K. Leslie> ;Cancers. 2021 Mar 5
• 7 citations
  Advantages of Tyrosine Kinase Anti-Angiogenic Cediranib over Bevacizumab: Cell Cycle Abrogation and Synergy with Chemotherapy
  Jianling Bi, Garima Dixit, Yuping Zhang, Eric J. Devor, Haley A Losh, A.M. Newtson, Kristen L Coleman, Donna A. Santillan, Thorsten Maretzky, Kristina W. Thiel, Kimber...> ;Pharmaceuticals. 2021 Jul 16
• 38 citations
  Mutated p53 portends improvement in outcomes when bevacizumab is combined with chemotherapy in advanced/recurrent endometrial cancer: An NRG Oncology study.
  Kimberly K. Leslie, Virginia L. Filiaci, Adrianne R. Mallen, Kristina W. Thiel, Eric J. Devor, Katherine M. Moxley, Debra L. Richardson, David G. Mutch, Angeles Alvare...> ;Gynecologic Oncology. 2021 Apr 1
• 13 citations
  Characterizing TP53 mutations in ovarian carcinomas with and without concurrent BRCA1 or BRCA2 mutations
  Talayeh Ghezelayagh, Kathryn P. Pennington, Barbara M. Norquist, Nithisha Khasnavis, Marc R. Radke, Mark R. Kilgore, Rochelle L. Garcia, Ming Lee, Ronit Katz, Kimberly...> ;Gynecologic Oncology. 2021 Mar 1
• 2 citations
  The Dawning of the Age of Personalized Medicine in Gynecologic Oncology.
  Kimberly K. Leslie, Kristina W. Thiel, Doris M. Benbrook, David G. Mutch> ;Cancers. 2020 Oct 27
• 14 citations
  Genomic characterization of five commonly used endometrial cancer cell lines
  Eric J. Devor, Jesus Gonzalez Bosquet, Kristina W. Thiel, Kimberly K. Leslie> ;International Journal of Oncology. 2020 Dec 1
• 11 citations
  Survival of Pregnant Coronavirus Patient on Extracorporeal Membrane Oxygenation.
  Sharon Beth Larson, Sarah N. Watson, Michael Eberlein, Jonathan S. Simmons, Kevin C. Doerschug, Kimberly K. Leslie> ;The Annals of Thoracic Surgery. 2021 Mar 1
• 5 citations
  Loss of progesterone receptor through epigenetic regulation is associated with poor prognosis in solid tumors.
  Yiyang Li, Cheng Huang, Tamar Kavlashvili, Abby Fronk, Yuping Zhang, Yang Wei, Donghai Dai, Eric J. Devor, Xiangbing Meng, Kristina W. Thiel, Kimberly K. Leslie, Shuji...> ;American Journal of Cancer Research. 2020 Jun 1
• 8 citations
  Characterization of a TP53 Somatic Variant of Unknown Function From an Ovarian Cancer Patient Using Organoid Culture and Computational Modeling.
  Jianling Bi, Kristina W. Thiel, Jacob M. Litman, Yuping Zhang, Eric J. Devor, Andreea M. Newtson, Michael J. Schnieders, Jesus Gonzalez Bosquet, Kimberly K. Leslie> ;Clinical Obstetrics and Gynecology. 2020 Mar 1
• Foreword: New and Novel Treatments for Gynecologic Cancer.
  Kimberly K Leslie, Jesus Gonzalez Bosquet> ;Clinical Obstetrics and Gynecology. 2020 Mar 1
• 19 citations
  Differential DNA methylation in high-grade serous ovarian cancer (HGSOC) is associated with tumor behavior
  Henry D. Reyes, Eric J. Devor, Akshaya Warrier, Andreea M. Newtson, Jordan Mattson, Vincent Wagner, Gabrielle N. Duncan, Kimberly K. Leslie, Jesus Gonzalez-Bosquet> ;Scientific Reports. 2019 Nov 29
• 12 citations
  MTDH/AEG-1 downregulation using pristimerin-loaded nanoparticles inhibits Fanconi anemia proteins and increases sensitivity to platinum-based chemotherapy
  Jianling Bi, Sudartip Areecheewakul, Yujun Li, Shujie Yang, Yuping Zhang, Kareem Ebeid, Long Li, Kristina W. Thiel, Jun Zhang, Donghai Dai, Aliasger K. Salem, Kimberly...> ;Gynecologic Oncology. 2019 Nov 1
• 40 citations
  Metadherin enhances vulnerability of cancer cells to ferroptosis.
  Jianling Bi, Shujie Yang, Long Li, Qun Dai, Brett A. Wagner, Garry R. Buettner, Douglas R. Spitz, Kimberly K. Leslie, Jun Zhang, Xiangbing Meng, Nicholas Borcherding> ;Cell Death & Disease. 2019 Sep 17
• 14 citations
  An integrated prediction model of recurrence in endometrial endometrioid cancers
  M.D. Miller, E. Salinas, Andreea M Newtson, Deepti Sharma, Matthew E Keeney, Akshaya Warrier, Brian J. Smith, David Bender, Michael J. Goodheart, Kristina W. Thiel, Er...> ;Cancer Management and Research. 2019 Jun 6
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