KirkRDaffnerMD

Neurology • Boston, MA

Chief, Division of Cognitive and Behavioral Neurology, Brigham and Womens Hospital

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Office
Division of Cognitive and Behavioral Neurology, Brigham and Women's Hospital
60 Fenwood Road
Boston, MA 02115
Phone+1 617-732-8060

Fax+1 617-738-9122
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Education & Training

Brigham and Women's Hospital/Massachusetts General Hospital/Harvard Medical SchoolResidency, Neurology, 1985 - 1988
Beth Israel Deaconess Medical CenterInternship, Internal Medicine, 1984 - 1985
Harvard Medical SchoolClass of 1984

Certifications & Licensure

MA State Medical License 1987 - 2025
VT State Medical License 2023 - 2024
ME State Medical License 2022 - 2024
RI State Medical License 2022 - 2024
CT State Medical License 2022 - 2023
American Board of Psychiatry and Neurology Neurology
UCNSBehavioral Neurology

Awards, Honors, & Recognition

Super Doctor SuperDoctors.com

Publications & Presentations

PubMed

Case Study 6: The Diagnostic Challenge of a 75-Year-Old Man Who Had, Then Didn't Have, Then Did Have Alzheimer's Disease.
Sergio A Ramírez-Salazar, Cassie MacRae, Mel B Feany, Michael Miller, Hyun-Sik Yang, Mary-Ellen Meadows, Scott M McGinnis, David Silbersweig, Seth A Gale, Kirk R Daffner> ;The Journal of Neuropsychiatry and Clinical Neurosciences. 2023 Jan 1
Case Study 4: A 68-Year-Old Woman With Progressive Cognitive Decline and Anxiety.
Rishab Gupta, Vihar Patel, Scott M McGinnis, David Silbersweig, Michael B Miller, Mel B Feany, Kirk Daffner, Seth A Gale> ;The Journal of Neuropsychiatry and Clinical Neurosciences. 2023 Jan 1
Case Study 5: A 74-Year-Old Man With Dysphagia, Weakness, and Memory Loss.
Scott M McGinnis, Ruth F McCann, Viharkumar Patel, Christopher T Doughty, Michael B Miller, Seth A Gale, David A Silbersweig, Kirk R Daffner> ;The Journal of Neuropsychiatry and Clinical Neurosciences. 2023 Jan 1
Non-Pharmacological Treatments of Neuropsychiatric Symptoms in Mild Cognitive Impairment.
Kristina Thurin, Kirk Daffner, Seth Gale, Nancy J Donovan, Juan Carlos Urizar> ;Seminars in Neurology. 2022 Apr 1
Case Study 3: A 58-Year-Old Woman Referred for Evaluation of Suspected Alzheimer Dementia.
Jeffrey Maneval, Jared K Woods, Mel B Feany, Michael B Miller, David A Silbersweig, Seth A Gale, Kirk R Daffner, Scott M McGinnis> ;The Journal of Neuropsychiatry and Clinical Neurosciences. 2022 Jan 1
Case Study 2: A 60-Year-Old Man With Progressive Deficits in Language Output.
Kristina Thurin, Viharkumar Patel, David L Perez, Bradford C Dickerson, Daisy Hochberg, Megan Quimby, Michael B Miller, Mel Feany, David Silbersweig, Scott M McGinnis,...> ;The Journal of Neuropsychiatry and Clinical Neurosciences. 2022 Jan 1
7 citations
BDNF mediates improvement in cognitive performance after computerized cognitive training in healthy older adults.
Casey M Nicastri, Brittany M McFeeley, Sharon S Simon, Aurélie Ledreux, Krister Håkansson, Ann-Charlotte Granholm, Abdul H Mohammed, Kirk R Daffner> ;Alzheimer's & Dementia. 2022 Jan 1
1 citations
Case Study 1: A 55-Year-Old Woman With Progressive Cognitive, Perceptual, and Motor Impairments
Scott M. McGinnis, Andrew M Stern, Jared K Woods, Matthew Torre, Mel B. Feany, Michael B Miller, David Silbersweig, Seth A. Gale, Kirk R. Daffner> ;The Journal of Neuropsychiatry and Clinical Neurosciences. 2021 Nov 12
2 citations
The Heuristic Power of Clinical Case Conferences: A New Section in the Journal of Neuropsychiatry and Clinical Neurosciences.
Kirk R. Daffner, Scott M. McGinnis, Seth A. Gale, David Silbersweig, C. Alan Anderson, David B. Arciniegas> ;The Journal of Neuropsychiatry and Clinical Neurosciences. 2021 Nov 12
45 citations
Promoting Successful Cognitive Aging: A Ten-Year Update.
Taylor J. Krivanek, Seth A. Gale, Brittany M. McFeeley, Casey M. Nicastri, Kirk R. Daffner> ;Journal of Alzheimer's Disease. 2021 Jan 1
Rebuttal: Accounting for the Community's Reciprocal Obligations to Healthcare Workers During a Pandemic.
Kirk R. Daffner> ;Journal of Hospital Medicine. 2021 Feb 17
3 citations
Point: Healthcare Providers Should Receive Treatment Priority During a Pandemic.
Kirk R. Daffner> ;Journal of Hospital Medicine. 2021 Feb 17
5 citations
Capacity-limited resources are used for managing sensory degradation and cognitive demands: Implications for age-related cognitive decline and dementia.
Adam R. Billig, Nicole C. Feng, Hura Behforuzi, Brittany M. McFeeley, Casey M. Nicastri, Kirk R. Daffner> ;Cortex; a Journal Devoted to the Study of the Nervous System and Behavior. 2020 Sep 24
New-Onset Delusions Heralding an Underlying Neurodegenerative Condition: A Case Report and Review of the Literature.
Emily A. Ferenczi, Michael G. Erkkinen, Mel B. Feany, Barry S. Fogel, Kirk R. Daffner> ;The Journal of Clinical Psychiatry. 2020 Mar 31
5 citations
Cognitive Impairment in Aging Physicians: Current Challenges and Possible Solutions.
Gayatri Devi, Darren R. Gitelman, Daniel Z. Press, Kirk R. Daffner> ;Neurology. Clinical Practice. 2021 Apr 1
10 citations
The Brain Health Champion study: Health coaching changes behaviors in patients with cognitive impairment.
Hope E.M. Schwartz, Camden P. Bay, Brittany M. McFeeley, Taylor J. Krivanek, Kirk R. Daffner, Seth A. Gale> ;Alzheimer's & Dementia. 2019 Jan 1
5 citations
Markers of novelty processing in older adults are stable and reliable
Hura Behforuzi, Nicole C. Feng, Adam R. Billig, Eliza Ryan, Erich S. Tusch, Phillip J. Holcomb, Abdul H. Mohammed, Kirk R. Daffner> ;Frontiers in Aging Neuroscience. 2019 Jun 28
3 citations
Teaching NeuroImages: Persistent anterograde amnesia due to sequential, bilateral vascular damage to the Papez circuit.
Fabio Porto, Pedro L. de Almeida, Kirk R. Daffner> ;Neurology. 2019 Jun 11
13 citations
Feasibility of an at-home, web-based, interactive exercise program for older adults.
Nicole C. Feng, Eliza Ryan, Mhretab Kidane, Erich S. Tusch, Brittany M. McFeeley, Roger Carlsson, Abdul H. Mohammed, Krister Håkansson, Kirk R. Daffner> ;Alzheimer's & Dementia. 2019 Jan 1
23 citations
Differential Effects of Physical Exercise, Cognitive Training, and Mindfulness Practice on Serum BDNF Levels in Healthy Older Adults: A Randomized Controlled Intervent...
Aurélie Ledreux, Krister Håkansson, Roger Carlsson, Mhretab Kidane, Laura Columbo, Yvonne Terjestam, Eliza Ryan, Erich S. Tusch, Bengt Winblad, Kirk R. Daffner, Ann-Ch...> ;Journal of Alzheimer's Disease. 2019 Jan 1
166 citations
Dementia.
Seth A Gale, Kirk R Daffner, Diler Acar> ;The American Journal of Medicine. 2018 Oct 1
25 citations
Is Computerized Working Memory Training Effective in Healthy Older Adults? Evidence from a Multi-Site, Randomized Controlled Trial.
Sharon Sanz Simon, Erich S. Tusch, Nicole C. Feng, Krister Håkansson, Abdul H. Mohammed, Kirk R. Daffner> ;Journal of Alzheimer's Disease. 2018 Jan 1
6 citations
Task-Irrelevant Novel Sounds have Antithetical Effects on Visual Target Processing in Young and Old Adults.
Erich S. Tusch, Nicole C. Feng, Phillip J. Holcomb, Kirk R. Daffner> ;Frontiers in Aging Neuroscience. 2017 Oct 31
21 citations
Changes in Neural Activity Underlying Working Memory after Computerized Cognitive Training in Older Adults.
Erich S. Tusch, Brittany R. Alperin, Eliza Ryan, Phillip J. Holcomb, Abdul H. Mohammed, Kirk R. Daffner> ;Frontiers in Aging Neuroscience. 2016 Nov 8
8 citations
Increased Early Processing of Task-Irrelevant Auditory Stimuli in Older Adults.
Erich S. Tusch, Brittany R. Alperin, Phillip J. Holcomb, Kirk R. Daffner> ;Plos One. 2016 Nov 2
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Lectures

Neurology for the Non-Neurologist
Harvard Medical School ,Department Of Continuing Education, Kennebunkport, Maine - 6/16/2013

Press Mentions

7 Things to Do for a Healthier Brain After 50May 9th, 2023
Mass General Brigham Won’t Offer Biogen’s New Alzheimer’s DrugSeptember 28th, 2021
FDA Narrows Recommended Use of Biogen Alzheimer’s Therapy After Flood of CriticismJuly 8th, 2021
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Grant Support

ERP Investigations Of Novelty Processing In Different Patterns Of Cognitive AgingNational Institute On Aging2008–2011
ERP Investigations Of Novelty Processing In Aging And ADNational Institute On Aging2002–2006
Neurology Of Attention To Novel EventsNational Institute Of Mental Health1996–1998
Neurology Of Novelty-Seeking Behavior And CuriosityNational Institute Of Mental Health1995
The Neurology Of Novelty-Seeking Behavior And CuriosityNational Institute Of Mental Health1994

Hospital Affiliations

Brigham and Women's HospitalBoston, Massachusetts