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Kirk Knowlton, MD, Cardiology, Salt Lake City, UT, Intermountain Medical Center

KirkUKnowltonMDFACC, FAHA

Cardiology Salt Lake City, UT

Non-Invasive Cardiology, Preventive Cardiology, Cardiovascular Disease Genetics

Director of Cardiovascular Research Intermountain Health. Professor, Clinical Investigation, Intermountain Health. Adjunct Professor of Medicine, University of Utah

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Summary

  • I have a strong interest in understanding how and why patients develop heart failure, including abnormalities in DNA, infections of the heart like viral myocarditis, and the role of immune function in heart cells that affect cardiac performance. I've also made discoveries related to how heart cells communicate with each other to establish normal conduction. Clinically, I practice as a general cardiologist with a focus on heart failure and pulmonary hypertension, where I apply my research efforts to preventing the development of heart disease, promoting optimal recovery, and advancing the use of a person’s own biological characteristics to provide precision medicine.

Education & Training

  • UC San Diego Medical Center
    UC San Diego Medical Center Molecular Cardiology Research Fellowship, 1989 - 1991
  • University of California (San Diego) Medical Center
    University of California (San Diego) Medical CenterFellowship, Cardiovascular Disease, 1987 - 1989
  • Duke University Hospital
    Duke University HospitalResidency, Internal Medicine, 1984 - 1987
  • University of Utah School of Medicine
    University of Utah School of MedicineClass of 1984
  • Brigham Young University
    Brigham Young UniversityBA, Chemistry, 1977 - 1980

Certifications & Licensure

  • UT State Medical License
    UT State Medical License 2015 - 2026
  • CA State Medical License
    CA State Medical License 1987 - 2025
  • American Board of Internal Medicine Internal Medicine
  • American Board of Internal Medicine Cardiovascular Disease

Awards, Honors, & Recognition

  • Fellow American Heart Association
  • American Heart Association "Heart of Gold" Physician Honoree Utah Heart Association Gala, 2017
  • Inaugural Frederic C. Shean Endowed Lecturer University of Utah Grand Rounds, 2016
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Clinical Trials

Publications & Presentations

PubMed

Lectures

  • Recent Insights into the Mechanisms of Myocarditis 
    2019 ACC Scientific Session & Expo, New Orleans - 3/17/2019

Press Mentions

  • Reduction in BP Drives Treatment Preference for Hypertensive Patients
    Reduction in BP Drives Treatment Preference for Hypertensive PatientsDecember 20th, 2022
  • Gout Flares Linked to Temporary Increase in Cardiovascular Risk
    Gout Flares Linked to Temporary Increase in Cardiovascular RiskApril 8th, 2022
  • Can a Simple Technique During Vaccination Stop Myocarditis?
    Can a Simple Technique During Vaccination Stop Myocarditis?October 2nd, 2021
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Grant Support

  • Training In Cardiovascular Physiology And PharmacologyNational Heart, Lung, And Blood Institute2007–2011
  • Administative CoreNational Heart, Lung, And Blood Institute2007–2011
  • Adhesion Molecules Of The Intercalated DISC In CardiomyopathyNational Heart, Lung, And Blood Institute2007–2011
  • Molecular Pathways For Hypertrophy And CardiomyopathyNational Heart, Lung, And Blood Institute2005–2011
  • Cardiac SOCS Proteins: A Role In Enterovirus InfectionNational Heart, Lung, And Blood Institute2004–2007
  • Biomechanical Stress Pathways And CardiomyopathyNational Heart, Lung, And Blood Institute2005–2006
  • Core--Myocardial Cell Biology And Viral Vector FacilityNational Heart, Lung, And Blood Institute2005
  • Administrative CoreNational Heart, Lung, And Blood Institute2005
  • Dystrophin-Glycoprotein Complex In Viral CardiomyopathyNational Heart, Lung, And Blood Institute2001–2004
  • Core--Cell Biology And Viral Vector FacilityNational Heart, Lung, And Blood Institute2002
  • Dystrophin-Glyoprotein Complex And Dilated CardiomyopathyNational Heart, Lung, And Blood Institute2000–2002
  • Pathogenesis Of Viral Heart DiseaseNational Center For Research Resources2001
  • Myocyte Apoptosis And A Transgenic Heart Failure ModelNational Heart, Lung, And Blood Institute1999–2001
  • Regulation Of ANF Gene During Ventricular HypertrophyNational Heart, Lung, And Blood Institute1991–1995

Committees

  • Committee Member, Chair Nominating Committee, American Heart Association, Western States Affiliate 2017 - Present
  • Chair, Scientific Advisory Committee, The Medical Heart and Lung Foundation, Intermountain 2017 - Present
  • Member, Research Guidance Council, Intermountain Healthcare 2017 - Present
  • Member, National Research Committee, American Heart Association 2015 - 2016
  • President, American Heart Association, Western States Affiliate 2014 - 2016

Professional Memberships

  • Member
  • Immediate Past President of the Board of Directors, Western States Affiliate; Member, Precision Medicine Task Force
  • American Society of Clinical Investigation
    Member
  • International Society for Heart Research - ISHR
    Member
  • Association of Professors of Cardiology
    President 2015-2016
  • Association of University Cardiologists
    Member
  • Heart Failure Society of America
    Member

Other Languages

  • Spanish

Hospital Affiliations