Klaus T Gottlieb MD PhD

Biliary Tract Disease, Inflammatory Bowel Disease, Pancreas Disease

Klaus Gottlieb, MD

1315 South Miller St.Ste 101Santa Maria, CA 93454
Phone+1 805-349-2945
Fax+1 805-349-2887

Dr. Gottlieb is on Doximity

As a Doximity member, you’ll join more than three million U.S. healthcare professionals—including 85+% of physicians, and 2/3 of all NPs and PAs—in a private, secure network.

Gain access to free telehealth tools, such as our “call shielding” and one-way patient texting.
Connect with colleagues in the same hospital or clinic.
Read the latest clinical news, personalized to your specialty.

See Dr. Gottlieb's full profile Already have an account?

Summary

Dr. Klaus Gottlieb is a translational scientist in immunology drug development with American Board certifications in Internal Medicine and Gastroenterology. He holds an MD-PhD (Dr.med.) degree from Bonn University in Germany, an MBA from Indiana University, and a Master of Science in Biotechnology from Johns Hopkins.He was most recently employed at the FDA, Quintiles (IQVIA), and Synthetic Biologics, Inc. He is now a Medical Fellow with Eli Lilly and Company and practices gastroenterology part-time in Santa Maria, CA.

Education & Training

Johns Hopkins UniversityMS, Biotechnology, 2009 - 2012
Indiana University School of MedicineFellowship, Gastroenterology, 1993 - 1995
Loyola University Medical CenterFellowship, Gastroenterology, 1991 - 1993
Loyola University Medical CenterResidency, Internal Medicine, 1988 - 1991
University of Bonn Faculty of MedicineClass of 1987

The following disclaimer is related to board certifications obtained from ABMS®, denoted by the ABMS® logo.

This information is proprietary data maintained in a copyrighted database owned by the American Board of Medical Specialties®. The display and presence of ABMS Data in no way constitutes any affiliation, association with, or endorsement of any advertising, promotion, or sponsorship by ABMS and its affiliates and subsidiaries, the ABMS Member Boards, or ABMS board certified physicians and medical specialists. Copyright 2026 American Board of Medical Specialties®. All rights reserved.

The user is responsible for ensuring that the profile obtained in this directory is the profile of the physician or medical specialist being sought.

A self-designated specialty, subspecialty, or practice area neither implies nor is equivalent to ABMS board certification or the existence of specialized training by or competence of a physician or medical specialist.

Certifications & Licensure

CA State Medical License 2016 - 2026
WA State Medical License 1998 - 2024
IL State Medical License 1989 - 1993

Awards, Honors, & Recognition

Fellow (FASGE) American Society for Gastrointestinal Endoscopy
Fellow (FACP) American College of Physicians, 1995
Fellow (FACG) American College of Gastroenterology

Clinical Trials

A Study to Evaluate the Effect of SYN-004 on the PK of IV Ceftriaxone in Adults With a Functioning Ileostomy Start of enrollment: 2015 Mar 01
Completed
Phase 1, Phase 2
A Study of the Effect of SYN-010 on Subjects With IBS-C Start of enrollment: 2015 Jun 01
Completed
Phase 2
A Study of SYN-004 for the Prevention of C.Diff in Patients With a LRTI Start of enrollment: 2015 Oct 01
Completed
Phase 2

Publications & Presentations

PubMed

Artificial intelligence assessment of endoscopic severity and extent: A machine learning approach to continuous evaluation of endoscopic inflammation in ulcerative col...
Alvin T George, Klaus Gottlieb, Daniel R Colucci, William J Eastman, Shrujal Baxi
Inflammatory Bowel Diseases. 2026-07-17
Machine Learning Models for the Assessment of the Mayo Endoscopic Score in Ulcerative Colitis Trial Endpoints: A Systematic Review.
David T Rubin, Walter Reinisch, Neeraj Narula, Daniel R Colucci, William Eastman
Inflammatory Bowel Diseases. 2026-01-01
Comparative evaluation of a hybrid machine learning-human adjudication paradigm for endoscopic scoring in ulcerative colitis.
Klaus T Gottlieb, Chakib Battioui, Yeli Wang, Pavel A Brodskiy, Mohammad Haft-Javaherian
BMJ Open Gastroenterology. 2025-12-07

Press Mentions

Synthetic Biologics Expands Clinical & Regulatory Leadership Team with Addition of Klaus Gottlieb, MD, FACGJune 2nd, 2015
Promising Celiac Disease Therapies on the HorizonMarch 9th, 2015