KrystalBottomMD

Pediatric Hematology & Oncology • Asheville, NC

Pediatric Hem/Onc attending at Mission Hospital

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Office
21 Hospital Dr
Asheville, NC 28801
Phone+1 828-213-9770

Fax+1 828-213-9771
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Education & Training

Duke University HospitalFellowship, Pediatric Hematology/Oncology, 1996
University of South Florida MorsaniResidency, Pediatrics, 1989 - 1992
University of Florida College of MedicineClass of 1989

Certifications & Licensure

NC State Medical License 1996 - 2024
American Board of Pediatrics Pediatric Hematology-Oncology

Clinical Trials

Isotretinoin With or Without Dinutuximab, Aldesleukin, and Sargramostim Following Stem Cell Transplant in Treating Patients With Neuroblastoma Start of enrollment: 2001 Oct 18
Active, not recruiting
Phase 3
Collecting and Storing Malignant, Borderline Malignant Neoplasms, and Related Samples From Young Patients With Cancer Start of enrollment: 2003 Oct 13
Completed
Study of Kidney Tumors in Younger Patients Start of enrollment: 2006 Feb 27
Recruiting
Collecting and Storing Biological Samples From Patients With Ewing Sarcoma Start of enrollment: 2008 Feb 04
Completed
Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma Start of enrollment: 2000 Nov 06
Recruiting
Risk-Based Classification System of Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Start of enrollment: 2010 Aug 09
Completed
Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma Start of enrollment: 2010 Aug 09
Active, not recruiting
Phase 3
Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma Start of enrollment: 2010 Nov 22
Active, not recruiting
Phase 3
Levofloxacin in Preventing Infection in Young Patients With Acute Leukemia Receiving Chemotherapy or Undergoing Stem Cell Transplantation Start of enrollment: 2011 Sep 01
Completed
Phase 3
A Phase III Randomized Trial for Newly Diagnosed High Risk B-precursor Acute Lymphoblastic Leukemia (ALL) Testing Clofarabine (IND# 73789, NSC# 606869) in the Very High Risk Stratum Start of enrollment: 2012 Feb 01
Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment Start of enrollment: 2014 Mar 05
Recruiting
Blood Sample Markers of Reproductive Hormones in Assessing Ovarian Reserve in Younger Patients With Newly Diagnosed Lymphomas Start of enrollment: 2013 Jun 17
Active, not recruiting
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Publications & Presentations

PubMed

56 citations
Phase II study of irinotecan (CPT-11) in children with high-risk malignant brain tumors: the Duke experience.
Christopher D. Turner, Sridharan Gururangan, James D. Eastwood, Krystal S. Bottom, Melody A. Watral, Rodney Beason, Roger E. McLendon, Allan H. Friedman, Sandra Tourt-...> ;Neuro-Oncology. 2002 Apr 1
6 citations
Evaluation of Pre-radiotherapy Cyclophosphamide in Patients with Newly Diagnosed Glioblastoma Multiforme
Krystal S. Bottom, David M. Ashley, Henry S. Friedman, Darryl C. Longee> ;Journal of Neuro-Oncology. 2000 Jan 1
24 citations
Gliomatosis cerebri: cytologic and autopsy findings in a case involving the entire neuraxis.
Thomas J. Cummings, Christine M. Hulette, Darryl C. Longee, Krystal S. Bottom, Roger E. McLendon, Charleen T. Chu> ;Clinical Neuropathology. 1999 Jul 1
15 citations
Phase II study of carboplatin (CBDCA) in progressive low-grade gliomas
Albert Moghrabi, Henry S. Friedman, David M. Ashley, Krystal S. Bottom, Tracy Kerby, Elizabeth A. Stewart, Carol S. Bruggers, James M. Provenzale, Martin A. Champagne,...> ;Neurosurgical Focus. 1998 Apr 15
12 citations
Trilineage hematopoietic toxicity associated with valproic acid therapy.
Krystal S. Bottom, Denise M. Adams, Karen P. Mann, Russell E. Ware> ;Journal of Pediatric Hematology/oncology. 1997 Jan 1
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