KunLuNP

PubMed

• 57 citations
  Pin1 inhibition potently suppresses gastric cancer growth and blocks PI3K/AKT and Wnt/β-catenin oncogenic pathways.
  Zhenzhen Zhang, Weixing Yu, Min Zheng, Xin-Hua Liao, Jichuang Wang, Da-Yun Yang, Wenxian Lu, Long Wang, Sheng Zhang, Hekun Liu, Xiao Zhen Zhou, Kun Ping Lu> ;Molecular Carcinogenesis. 2019 Aug 1
• 7 citations
  Targeting PIN1 exerts potent antitumor activity in pancreatic ductal carcinoma via inhibiting tumor metastasis
  Linying Chen, Xiao Xu, Xinxin Wen, Shenmin Xu, Long Wang, Wenxian Lu, Mingting Jiang, Jing Huang, Da-Yun Yang, Jichuang Wang, Min Zheng, Xiao Zhen Zhou, Kun Ping Lu, H...> ;Cancer Science. 2019 Jun 25
• 19 citations
  Quantitative proteomics reveals systematic dysregulations of liver protein metabolism in sucralose-treated mice.
  Chih-Wei Liu, Liang Chi, Pengcheng Tu, Jingchuan Xue, Hongyu Ru, Kun Lu> ;Journal of Proteomics. 2019 Mar 30
• 23 citations
  Subchronic low-dose 2,4-D exposure changed plasma acylcarnitine levels and induced gut microbiome perturbations in mice
  Pengcheng Tu, Bei Gao, Liang Chi, Yunjia Lai, Xiaoming Bian, Hongyu Ru, Kun Lu> ;Scientific Reports. 2019 Mar 13
• 33 citations
  Pin1 inhibition reverses the acquired resistance of human hepatocellular carcinoma cells to Regorafenib via the Gli1/Snail/E-cadherin pathway.
  Jichuang Wang, Nan Zhang, Qi Han, Wenxian Lu, Long Wang, Da-Yun Yang, Min Zheng, Zhenzhen Zhang, Hekun Liu, Tae Ho Lee, Xiao Zhen Zhou, Kun Ping Lu> ;Cancer Letters. 2019 Mar 1
• 45 citations
  SPOP Promotes Nanog Destruction to Suppress Stem Cell Traits and Prostate Cancer Progression.
  Jinfang Zhang, Ming Chen, Yasheng Zhu, Xiangpeng Dai, Fabin Dang, Junming Ren, Shancheng Ren, Yulia V. Shulga, Francisco Beca, Wenjian Gan, Fei Wu, Yu-Min Lin, Xiaobo ...> ;Developmental Cell. 2019 Feb 11
• 33 citations
  An IRAK1-PIN1 signalling axis drives intrinsic tumour resistance to radiation therapy.
  Peter H. Liu, Richa B. Shah, Yuanyuan Li, Arshi Arora, Peter Man-Un Ung, Renuka Raman, Andrej Gorbatenko, Shingo Kozono, Xiao Zhen Zhou, Vincent Brechin, John M. Barba...> ;Nature Cell Biology. 2019 Jan 21
• 51 citations
  Gut microbiome disruption altered the biotransformation and liver toxicity of arsenic in mice
  Liang Chi, Jingchuan Xue, Pengcheng Tu, Yunjia Lai, Hongyu Ru, Kun Lu> ;Archives of Toxicology. 2019 Jan 1
• 100 citations
  Arsenic targets Pin1 and cooperates with retinoic acid to inhibit cancer-driving pathways and tumor-initiating cells
  Shingo Kozono, Yu-Min Lin, Hyuk-Soo Seo, Benika J. Pinch, Xiaolan Lian, Chenxi Qiu, Megan K. Herbert, Chun-Hau Chen, Li Tan, Ziang Jeff Gao, Walter Massefski, Zainab M...> ;Nature Communications. 2018 Aug 9
• 20 citations
  Individual susceptibility to arsenic-induced diseases: the role of host genetics, nutritional status, and the gut microbiome.
  Liang Chi, Bei Gao, Pengcheng Tu, Chih-Wei Liu, Jingchuan Xue, Yunjia Lai, Hongyu Ru, Kun Lu> ;Mammalian Genome. 2018 Feb 10
• 47 citations
  Effects of the Artificial Sweetener Neotame on the Gut Microbiome and Fecal Metabolites in Mice
  Liang Chi, Xiaoming Bian, Bei Gao, Pengcheng Tu, Yunjia Lai, Hongyu Ru, Kun Lu> ;Molecules. 2018 Feb 9
• 247 citations
  Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model.
  Chad A. Tagge, Andrew M. Fisher, Olga Minaeva, Amanda Gaudreau-Balderrama, Juliet A. Moncaster, Xiao-Lei Zhang, Mark W. Wojnarowicz, Noel Casey, Haiyan Lu, Olga N. Kok...> ;Brain. 2018 Feb 1
• 21 citations
  The organophosphate malathion disturbs gut microbiome development and the quorum-Sensing system.
  Bei Gao, Liang Chi, Pengcheng Tu, Xiaoming Bian, Jesse Thomas, Hongyu Ru, Kun Lu> ;Toxicology Letters. 2018 Feb 1
• 11 citations
  Targeting Prion-like Cis Phosphorylated Tau Pathology in Neurodegenerative Diseases.
  Onder Albayram, Peter Angeli, Elizabeth Bernstein, Sean Baxley, Ziang Gao, Kun Ping Lu, Xiao Zhen Zhou> ;Journal of Alzheimer's Disease & Parkinsonism. 2018 Jan 1
• 32 citations
  Prolyl isomerase PIN1 regulates the stability, transcriptional activity and oncogenic potential of BRD4
  Xiangming Hu, Shi-Hui Dong, Jinjing Chen, Xiao Zhen Zhou, Ruichuan Chen, Satish K. Nair, Kun Ping Lu, Lin Feng Chen> ;Oncogene. 2017 May 8
• 177 citations
  The isomerase PIN1 controls numerous cancer-driving pathways and is a unique drug target.
  Xiao Zhen Zhou, Kun Ping Lu> ;Nature Reviews. Cancer. 2016 Jul 1
• 532 citations
  The prolyl isomerase PIN1: a pivotal new twist in phosphorylation signalling and disease
  Kun Ping Lu, Xiao Zhen Zhou> ;Nature Reviews. Molecular Cell Biology. 2007 Nov 1
• 472 citations
  Prolyl cis-trans isomerization as a molecular timer
  Kun Ping Lu, Greg Finn, Tae Ho Lee, Linda K. Nicholson> ;Nature Chemical Biology. 2007 Oct 1
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