LarryADonosoMDPhd, JD, MBA

Ophthalmology • Philadelphia, PA

Retinal Disease

Philadelphia Retina Endowment Fund

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Office
Po Box 53429
Philadelphia, PA 19105
Phone+1 215-928-1060
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Education & Training

Sidney Kimmel Medical College at Thomas Jefferson UniversityPost-Doctoral Fellowship, Clinical/Reserch, 1980 - 1981
University of Utah School of MedicineClass of 1973

Certifications & Licensure

PA State Medical License Current
American Board of Ophthalmology Ophthalmology

Clinical Trials

Electric Stimulation of the Eye to Improve Vision After Trauma Start of enrollment: 2013 Jul 01
Completed
Not Applicable

Publications & Presentations

PubMed

42 citations
Neuroprotection for glaucoma: Requirements for clinical translation
Leonard A. Levin, Megan E. Crowe, Harry A. Quigley, M Francesca Cordeiro, Larry A. Donoso, Y. Joyce Liao, Richard T. Libby, Richard H. Masland, Robert W. Nickells, Pau...> ;Experimental Eye Research. 2017 Apr 1
2 citations
Chapter 8 - Restoring Vision to the Blind: Evaluating Visual Function, Endpoints.
David G. Birch, Fred W. Fitzke, Gary S. Rubin, Blake R. Hopiavuori, Ernst Bamberg, Alan C. Bird, Larry A. Donoso, Jacque L. Duncan, D.C. Hood, Alan M. Laties, Paul A. ...> ;Translational Vision Science & Technology. 2014 Dec 30
240 citations
Innovations in 3D printing: a 3D overview from optics to organs
Carl Schubert, Mark Christensen van Langeveld, Larry A. Donoso> ;The British Journal of Ophthalmology. 2014 Feb 1
5 citations
Topical aqueous suppression does not significantly affect duration of intraocular gas tamponade after vitrectomy.
Chirag P. Shah, Jason Hsu, Marc J. Spirn, Larry A. Donoso, Sunir J. Garg> ;Retina. 2012 Jan 1
39 citations
Role of Complement Cascade in Abdominal Aortic Aneurysms
Irene Hinterseher, Robert Erdman, Larry A. Donoso, Tamara R. Vrabec, Charles M. Schworer, John H Lillvis, Amy M. Boddy, Kimberly Derr, Alicia Golden, William D. Bowen,...> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2011 Jul 1
63 citations
The role of complement Factor H in age-related macular degeneration: a review.
Larry A. Donoso, Tamara R. Vrabec, Helena Kuivaniemi> ;Survey of Ophthalmology. 2010 May 1
420 citations
Genetic variants near TIMP3 and high-density lipoprotein–associated loci influence susceptibility to age-related macular degeneration
Wei Chen, Dwight Stambolian, Albert O. Edwards, Kari Branham, Mohammad Othman, Johanna Jakobsdottir, Nirubol Tosakulwong, Margaret A. Pericak-Vance, Peter A. Campochia...> ;Proceedings of the National Academy of Sciences of the United States of America. 2010 Apr 20
29 citations
Analysis of six genetic risk factors highly associated with AMD in the region surrounding ARMS2 and HTRA1 on chromosome 10, region q26.
Dexter Hadley, Anton Orlin, Gary C. Brown, Alexander J. Brucker, Allen C. Ho, Carl D. Regillo, Larry A. Donoso, Lifeng Tian, Brian Kaderli, Dwight Stambolian> ;Investigative Ophthalmology & Visual Science. 2010 Apr 1
32 citations
Repertoire Analysis and New Pathogenic Epitopes of IRBP in C57BL/6 (H-2b) and B10.RIII (H-2r) Mice
Lizette M. Cortes, Mary J. Mattapallil, Phyllis B. Silver, Larry A. Donoso, Gregory I. Liou, Wei Zhu, Chi-Chao Chan, Rachel R. Caspi> ;Investigative Ophthalmology & Visual Science. 2008 May 1
6 citations
X-linked retinoschisis: novel mutation in the initiation codon of the XLRS1 gene in a large family.
David Y Kim, Kimberly A. Neely, Joseph W. Sassani, Tamara R. Vrabec, Avinash Tantri, Arcilee Frost, Larry A. Donoso> ;Retina. 2006 Oct 1
371 citations
The Role of Inflammation in the Pathogenesis of Age-related Macular Degeneration
Larry A. Donoso, David Y Kim, Arcilee Frost, Alston Callahan, Gregory S. Hageman> ;Survey of Ophthalmology. 2006 Mar 1
6 citations
Autosomal dominant pattern dystrophy: identification of a novel splice site mutation in the peripherin/RDS gene.
Farzad J Khoubian, Eric P. Shakin, Avinash Tantri, David Y Kim, Albert O. Edwards, Larry A. Donoso> ;Retina. 2005 Dec 1
159 citations
X-linked retinoschisis: A clinical and molecular genetic review
Avinash Tantri, Tamara R. Vrabec, Andrew Cu-Unjieng, Arcilee Frost, William H. Annesley, Larry A. Donoso> ;Survey of Ophthalmology. 2004 Mar 1
9 citations
Ocular surface epithelium induces expression of human mucosal lymphocyte antigen (HML-1) on peripheral blood lymphocytes.
José Álvaro Pereira Gomes, Harminder S Dua, Luiz Vicente Rizzo, Mauro Nishi, A Joseph, Larry A. Donoso> ;The British Journal of Ophthalmology. 2004 Feb 1
60 citations
An immunologically privileged retinal antigen elicits tolerance: major role for central selection mechanisms.
Dody Avichezer, Rafael S. Grajewski, Chi-Chao Chan, Mary J. Mattapallil, Phyllis B. Silver, James Raber, Gregory I. Liou, Barbara Wiggert, Giavonni M. Lewis, Larry A. ...> ;The Journal of Experimental Medicine. 2003 Dec 1
20 citations
Interphotoreceptor retinoid-binding protein (IRBP)-deficient C57BL/6 mice have enhanced immunological and immunopathogenic responses to IRBP and an altered recognition...
Dody Avichezer, Gregory I. Liou, Chi-Chao Chan, Giavonni M. Lewis, Barbara Wiggert, Larry A. Donoso, John M. Nickerson, Mary Alice Crawford, Rachel R. Caspi> ;Journal of Autoimmunity. 2003 Nov 1
6 citations
X-linked retinoschisis: report of a family with a rare deletion in the xLRS1 gene ☆
Avinash Tantri, Tamara R. Vrabec, Andrew Cu-Unjieng, Arcilee Frost, William H. Annesley, Larry A. Donoso> ;American Journal of Ophthalmology. 2003 Sep 1
5 citations
Autosomal dominant Stargardt-like macular dystrophy: identification of a new family with a mutation in the ELOVL4 gene.
Tamara R. Vrabec, Avinash Tantri, Albert O. Edwards, Arcilee Frost, Larry A. Donoso> ;American Journal of Ophthalmology. 2003 Sep 1
71 citations
A humanized model of experimental autoimmune uveitis in HLA class II transgenic mice
Giuseppina Pennesi, Mary J. Mattapallil, Shu Hui Sun, Dody Avichezer, Phyllis B. Silver, Zaruhi Karabekian, Chella S. David, Paul A. Hargrave, J. Hugh McDowell, W. Cla...> ;The Journal of Clinical Investigation. 2003 Apr 15
59 citations
Clinical variability of Stickler syndrome: role of exon 2 of the collagen COL2A1 gene.
Larry A. Donoso, Albert O. Edwards, Arcilee Frost, Robert Ritter, N. Nina Ahmad, Tamara R. Vrabec, Jerry Rogers, David Meyer, Scott Parma> ;Survey of Ophthalmology. 2003 Mar 1
7 citations
Autosomal dominant macular dystrophy in a large Canadian family.
Larry A. Donoso, Gregory S. Hageman, Arcilee Frost, Val C. Sheffield, John S. Beck, Marc Hébert, Ian M. MacDonald> ;Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie. 2003 Feb 1
31 citations
Identification of GUCY2D gene mutations in CORD5 families and evidence of incomplete penetrance.
Nitin Udar, S. Yelchits, Meenal Chalukya, Vivek S. Yellore, Steve Nusinowitz, Rosamaria Silva-Garcia, Tamara R. Vrabec, Irene H. Maumenee, Larry A. Donoso, Kent W. Small> ;Human Mutation. 2003 Feb 1
34 citations
Isolation and Expression of an Arrestin cDNA from the Horseshoe Crab Lateral Eye
W C Smith, R M Greenberg, Bruce G. Calman, M M Hendrix, L Hutchinson, Larry A. Donoso, Barbara-Anne Battelle> ;Journal of Neurochemistry. 2002 Nov 23
36 citations
Identification of a stop codon mutation in exon 2 of the collagen 2A1 gene in a large stickler syndrome family.
Larry A. Donoso, Albert O. Edwards, Arcilee Frost, Robert Ritter, N. Nina Ahmad, Tamara R. Vrabec, Jerry Rogers, David Meyer> ;American Journal of Ophthalmology. 2002 Nov 1
85 citations
A novel gene for autosomal dominant Stargardt-like macular dystrophy with homology to the SUR4 protein family.
Albert O. Edwards, Larry A. Donoso, Robert Ritter> ;Investigative Ophthalmology & Visual Science. 2001 Oct 1
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