LauraFNewellMD

PubMed

• CPX-351 Pharmacokinetics and Safety in Adults with Hematologic Malignancies and Renal Function Impairment: Phase 1 Trial.
  Scott R Solomon, Bayard L Powell, Jamie Koprivnikar, Catherine Lai, Heather Male, Laura C Michaelis, Laura F Newell, David Sanford, Jack Jenkins, Amy Zelaya, Sheryl Co...> ;Cancers. 2024 Feb 24
• 22 citations
  Comparison and validation of the 2022 European LeukemiaNet guidelines in acute myeloid leukemia.
  Curtis A Lachowiez, Nicola Long, Jennifer Saultz, Arpita Gandhi, Laura F Newell, Brandon Hayes-Lattin, Richard T Maziarz, Jessica Leonard, Daniel Bottomly, Shannon McW...> ;Blood Advances. 2023 May 9
• Day 4 collection of granulocyte colony-stimulating factor-mobilized HLA-matched sibling donor peripheral blood allografts demonstrates no long-term increase in chronic...
  Georgeann Booth, Yun Yu, Rogelyn P Harlan, Carol E Jacoby, Kaitlyn M Tomic, Susan E Slater, Bryon E Allen, Elizabeth M Berklich, Rebekah J Knight, Julieann Dela Cruz, ...> ;Cytotherapy. 2023 Apr 1
• A new beginning: can omidubicel emerge as the next, viable alternative donor source?
  Arpita P Gandhi, Laura F Newell, Richard T Maziarz> ;Therapeutic Advances in Hematology. 2023 Jan 1
• 7 citations
  Transplant outcomes after CPX-351 vs 7 + 3 in older adults with newly diagnosed high-risk and/or secondary AML.
  Geoffrey L Uy, Laura F Newell, Tara L Lin, Stuart L Goldberg, Matthew J Wieduwilt, Robert J Ryan, Stefan Faderl, Jeffrey E Lancet> ;Blood Advances. 2022 Sep 13
• 5 citations
  Acute GVHD: think before you treat.
  Laura F Newell, Shernan G Holtan> ;Hematology. American Society of Hematology. Education Program. 2021 Dec 10
• 168 citations
  Advances in acute myeloid leukemia
  Laura F. Newell, Rachel J. Cook> ;BMJ. 2021 Oct 6
• 11 citations
  Engrafted Donor-Derived Clonal Hematopoiesis after Allogenic Hematopoietic Cell Transplantation is Associated with Chronic Graft-versus-Host Disease Requiring Immunosu...
  Laura F. Newell, Todd Williams, James K. Liu, Yun Yu, Yiyi Chen, Georgeann C. Booth, R. Knight, Kelli R. Goslee, Rachel J. Cook, Jessica Leonard, Gabrielle Meyers, Eli...> ;Transplantation and Cellular Therapy. 2021 Aug 1
• 72 citations
  CPX-351 versus 7+3 cytarabine and daunorubicin chemotherapy in older adults with newly diagnosed high-risk or secondary acute myeloid leukaemia: 5-year results of a ra...
  Jeffrey E. Lancet, Geoffrey L. Uy, Laura F. Newell, Tara L. Lin, Ellen K. Ritchie, Robert K. Stuart, Stephen A. Strickland, Donna E. Hogge, Scott R. Solomon, Dale L. B...> ;The Lancet. Haematology. 2021 Jul 1
• 10 citations
  Graft-versus-host disease after liver transplantation is associated with bone marrow failure, hemophagocytosis, and DNMT3A mutations.
  Laura F. Newell, Jennifer Dunlap, Ken Gatter, Grover C. Bagby, Richard D. Press, Rachel J. Cook, Luke B Fletcher, Jessica Leonard, Kelli M. Leong, Joseph S. Bubalo, Al...> ;American Journal of Transplantation. 2021 May 7
• 13 citations
  Diurnal stability of cell-free DNA and cell-free RNA in human plasma samples.
  Josiah Tad Wagner, Hyun Ji Kim, Katie Johnson-Camacho, Taylor Kelley, Laura F. Newell, Paul T. Spellman, Thuy T.M. Ngo> ;Scientific Reports. 2020 Oct 5
• 2 citations
  Follistatin and Soluble Endoglin Predict 1-Year Nonrelapse Mortality after Allogeneic Hematopoietic Cell Transplantation.
  Laura F. Newell, Todd E. DeFor, Corey Cutler, Michael R. Verneris, Bruce R. Blazar, Jeffrey S. Miller, Joseph H. Antin, Alan Howard, Juan Wu, Margaret L. MacMillan, An...> ;Biology of Blood and Marrow Transplantation. 2020 Mar 1
• 5 citations
  Allogeneic transplantation outcomes amongst a contemporary cohort of high-risk myelodysplastic syndrome and acute myeloid leukemia patients aged ≥70 years.
  Curtis Lachowiez, Rachel J. Cook, Brandon Hayes-Lattin, Richard T. Maziarz, Uma Borate, Elie Traer, Jessica Leonard, Laura F. Newell, Kim Hien T. Dao, Gabrielle Meyers> ;Hematology/oncology and Stem Cell Therapy. 2019 Jun 1
• 2 citations
  Feasibility and Cost Analysis of Day 4 Granulocyte Colony-Stimulating Factor Mobilized Peripheral Blood Progenitor Cell Collection from HLA-Matched Sibling Donors
  Laura F. Newell, Kelsea M. Shoop, R. Knight, S. Murray, Carol Jacoby, Susan Slater, Bryon Allen, Casondra Ottowa, Brad Cota, Peggy Appel, Rachel J. Cook, Richard T. Ma...> ;Cytotherapy. 2019 Mar 1
• 11 citations
  A phase 2 study to assess the pharmacokinetics and pharmacodynamics of CPX-351 and its effects on cardiac repolarization in patients with acute leukemias
  Tara L. Lin, Laura F. Newell, Robert K. Stuart, Laura C. Michaelis, Eric Rubenstein, Helen S. Pentikis, Timothy Callahan, Donna Alvarez, Barry D. Liboiron, Lawrence D....> ;Cancer Chemotherapy and Pharmacology. 2019 May 16
• 26 citations
  Amphiregulin modifies the Minnesota Acute Graft-versus-Host Disease Risk Score: results from BMT CTN 0302/0802.
  Shernan G. Holtan, Todd E. DeFor, Angela Panoskaltsis-Mortari, Nandita Khera, John E. Levine, Mary E.D. Flowers, Stephanie J. Lee, Yoshihiro Inamoto, George Chen, Seba...> ;Blood Advances. 2018 Aug 14
• 559 citations
  CPX-351 (cytarabine and daunorubicin) Liposome for Injection Versus Conventional Cytarabine Plus Daunorubicin in Older Patients With Newly Diagnosed Secondary Acute My...
  Jeffrey E. Lancet, Geoffrey L. Uy, Jorge E. Cortes, Laura F. Newell, Tara L. Lin, Ellen K. Ritchie, Robert K. Stuart, Stephen A. Strickland, Donna E. Hogge, Scott R. S...> ;Journal of Clinical Oncology. 2018 Jul 19
• 8 citations
  Donor and recipient plasma follistatin levels are associated with acute GvHD in Blood and Marrow Transplant Clinical Trials Network 0402.
  Lucie M. Turcotte, Todd E. DeFor, Laura F. Newell, Corey Cutler, Michael R. Verneris, Juan Wu, Alan Howard, Margaret L. MacMillan, Joseph H. Antin, Gregory M. Vercello...> ;Bone Marrow Transplantation. 2018 Jan 1
• 11 citations
  PlGF enhances TLR-dependent inflammatory responses in human mononuclear phagocytes.
  Laura F. Newell, Shernan G. Holtan, Jane E. Yates, Leonardo Pereira, Jeffrey W. Tyner, Irina Burd, Grover C. Bagby> ;American Journal of Reproductive Immunology. 2017 Oct 1
• 8 citations
  Low EGF in myeloablative allotransplantation: association with severe acute GvHD in BMT CTN 0402.
  Shernan G. Holtan, L F Newell, Corey Cutler, Michael R. Verneris, Todd E. DeFor, Juan Wu, Alan Howard, Margaret L. MacMillan, Joseph H. Antin, Bruce R. Blazar, Daniel ...> ;Bone Marrow Transplantation. 2017 Jun 5
• 158 citations
  Identification of Interleukin-1 by Functional Screening as a Key Mediator of Cellular Expansion and Disease Progression in Acute Myeloid Leukemia
  Alyssa Carey, David K. Edwards, Christopher A. Eide, Laura F. Newell, Elie Traer, Bruno C. Medeiros, Daniel A. Pollyea, Michael W. Deininger, Robert H. Collins, Jeffre...> ;Cell Reports. 2017 Mar 28
• 4 citations
  Low day +100 serum epidermal growth factor levels are associated with acute GvHD after allogeneic hematopoietic cell transplantation.
  Fiona He, Michael R. Verneris, Sarah Cooley, Bruce R. Blazar, Margaret L. MacMillan, Laura F. Newell, Angela Panoskaltsis-Mortari, Todd E. DeFor, Daniel J. Weisdorf, S...> ;Bone Marrow Transplantation. 2017 Feb 1
• 23 citations
  Placental growth factor: What hematologists need to know.
  Laura F. Newell, Shernan G. Holtan> ;Blood Reviews. 2017 Jan 1
• 41 citations
  Late acute graft-versus-host disease: A prospective analysis of clinical outcomes and circulating angiogenic factors
  Shernan G. Holtan, Nandita Khera, John E. Levine, Xiaoyu Chai, Barry E. Storer, Hien D. Liu, Yoshihiro Inamoto, George Chen, Sebastian Mayer, Mukta Arora, Jeanne Palme...> ;Blood. 2016 Nov 10
• 66 citations
  Heterogeneity of chronic graft-versus-host disease biomarkers: association with CXCL10 and CXCR3+ NK cells
  Amina Kariminia, Shernan G. Holtan, Sabine Ivison, Jacob Rozmus, Marie-Josée Hébert, Paul J. Martin, Stephanie J. Lee, Daniel Wolff, Peter Subrt, Sayeh Abdossamadi, Su...> ;Blood. 2016 Jun 16
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Abstracts/Posters

• Outcomes in Patients with Therapy-Related Acute Myeloid Leukemia (t-AML) Who Achieved Remission with CPX-351 Versus 7+3: Phase 3 Exploratory AnalysisClinically Relevan...
  Laura F. Newell, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Phase 3 Exploratory Analysis of Outcomes in Patients with Acute Myeloid Leukemia with Myelodysplasia-Related Changes (AML-MRC) Who Received Consolidation with CPX-351 ...
  Laura F. Newell, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Outcomes in Patients with Acute Myeloid Leukemia with Myelodysplasia-Related Changes (AML-MRC) Who Achieved Remission with CPX-351 Versus 7+3: Phase 3 Exploratory Anal...
  Laura F. Newell, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019

Lectures

• Efficacy and Safety of CPX-351 Versus 7+3 in a Subgroup of Older Patients with Newly Diagnosed Acute Myeloid Leukemia with Myelodysplasia-Related Changes (AML-MRC) Enr... 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018