LaurenceTurkaMD

PubMed

• Harnessing regulatory T cells to establish immune tolerance.
  Patrick Ho, Ellen Cahir-McFarland, Jason D Fontenot, Tracey Lodie, Adel Nada, Qizhi Tang, Laurence A Turka, Jeffrey A Bluestone> ;Science Translational Medicine. 2024 Mar 13
• 4 citations
  Donor antigen-specific regulatory T cell administration to recipients of live donor kidneys: A ONE Study consortium pilot trial.
  Eva C Guinan, Laura Contreras-Ruiz, Kerry Crisalli, Charles Rickert, Ivy Rosales, Robert Makar, Robert Colvin, Edward K Geissler, Birgit Sawitzki, Paul Harden, Qizhi T...> ;American Journal of Transplantation. 2023 Dec 1
• 4 citations
  Ex vivo generation of regulatory T cells from liver transplant recipients using costimulation blockade
  Katsuyoshi Shimozawa, Laura Contreras-Ruiz, Sofia Sousa, Ruan Zhang, Urvashi Bhatia, Kerry C Crisalli, Lisa L. Brennan, Laurence A. Turka, James F. Markmann, Eva C. Gu...> ;American Journal of Transplantation. 2021 Sep 15
• Challenging the notion of conflict of interest in transplantation: Barriers at the intersection between innovation and clinical advancement.
  Oscar K. Serrano, Laurence A. Turka, David A. Axelrod> ;American Journal of Transplantation. 2021 Jul 24
• 8 citations
  Anti-tumor effects of RTX-240: an engineered red blood cell expressing 4-1BB ligand and interleukin-15.
  Shannon McArdel, Anne-Sophie Dugast, Maegan Hoover, Arjun Bollampalli, Enping Hong, Zafira Castaño, Shannon C. Leonard, Sneha Pawar, Jennifer Mellen, Kelvin Muriuki, D...> ;Cancer Immunology, Immunotherapy. 2021 Jul 9
• 25 citations
  Engineered red blood cells as an off-the-shelf allogeneic anti-tumor therapeutic
  Xuqing Zhang, Mengyao Luo, Shamael R. Dastagir, Mellissa J. Nixon, Annie Khamhoung, Andrea Schmidt, Albert Lee, Naren Subbiah, Douglas C. McLaughlin, Christopher L. Mo...> ;Nature Communications. 2021 May 11
• 42 citations
  Immunosuppression Withdrawal in Liver Transplant Recipients on Sirolimus
  Josh Levitsky, Bryna E. Burrell, Sai Kanaparthi, Laurence A. Turka, Sunil M. Kurian, Alberto Sanchez-Fueyo, Juan José Lozano, Anthony J. Demetris, Andrew Lesniak, Alla...> ;Hepatology. 2020 Aug 1
• 220 citations
  Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials.
  Birgit Sawitzki, Paul N. Harden, Petra Reinke, Aurélie Moreau, James A. Hutchinson, David Game, Qizhi Tang, Eva C. Guinan, Manuela Battaglia, William J. Burlingham, Ia...> ;Lancet. 2020 May 23
• 54 citations
  Beta cell-specific CD8+ T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes
  Hossam A. Abdelsamed, Caitlin C. Zebley, Hai Nguyen, Rachel L. Rutishauser, Yiping Fan, Hazem E. Ghoneim, Jeremy Chase Crawford, Francesca Alfei, Shanta Alli, Susan Pe...> ;Nature Immunology. 2020 Mar 30
• 27 citations
  Extensive intrathecal T cell renewal following hematopoietic transplantation for multiple sclerosis
  Kristina M. Harris, Noha Lim, Paul Lindau, Harlan Robins, Linda M. Griffith, Richard A. Nash, Laurence A. Turka, Paolo A. Muraro> ;JCI Insight. 2020 Jan 30
• 32 citations
  The Untapped Opportunity and Challenge of Immunometabolism: A New Paradigm for Drug Discovery.
  Claire Mazumdar, Edward M. Driggers, Laurence A. Turka> ;Cell Metabolism. 2020 Jan 7
• 19 citations
  Differential effects of 2-deoxy-D-glucose on in vitro expanded human regulatory T cell subsets.
  Naoki Tanimine, Sharon Germana, Martin Fan, Keli L. Hippen, Bruce R. Blazar, James F. Markmann, Laurence A. Turka, Bhavana Priyadharshini> ;Plos One. 2019 Jun 6
• 9 citations
  Targeting PI3Kδ function for amelioration of murine chronic graft-versus-host disease.
  Katelyn Paz, Ryan Flynn, Jing Du, Stacey Tannheimer, Amy J. Johnson, Shuai Dong, Anne-Katrien Stark, Klaus Okkenhaug, Angela Panoskaltsis-Mortari, Peter T. Sage, Arlen...> ;American Journal of Transplantation. 2019 Mar 19
• 39 citations
  Abatacept Targets T Follicular Helper and Regulatory T Cells, Disrupting Molecular Pathways That Regulate Their Proliferation and Maintenance.
  Simon Glatigny, Barbara Höllbacher, Samantha Motley, Cathy Tan, Christian Hundhausen, Jane H. Buckner, Dawn E. Smilek, Samia J. Khoury, Linna Ding, Tielin Qin, Jorge P...> ;Journal of Immunology. 2019 Jan 25
• 272 citations
  Mitochondrial complex III is essential for suppressive function of regulatory T cells.
  Samuel E. Weinberg, Benjamin D. Singer, Elizabeth M. Steinert, Carlos A. Martinez, Manan M. Mehta, Inmaculada Martínez-Reyes, Peng Gao, Kathryn A. Helmin, Hiam Abdala-...> ;Nature. 2019 Jan 9
• 46 citations
  Early expansion of donor-specific Tregs in tolerant kidney transplant recipients
  Thomas Savage, Brittany Shonts, Aleksandar Obradovic, Susan DeWolf, Sai-Ping Lau, Julien Zuber, Michael T. Simpson, Erik Berglund, Jianing Fu, Suxiao Yang, Siu-hong Ho...> ;JCI Insight. 2018 Nov 15
• 91 citations
  Differential Roles of IL-2 Signaling in Developing versus Mature Tregs
  Martin Fan, Jun Siong Low, Naoki Tanimine, Kelsey K. Finn, Bhavana Priyadharshini, Sharon Germana, Susan M. Kaech, Laurence A. Turka> ;Cell Reports. 2018 Oct 30
• 27 citations
  The vimentin intermediate filament network restrains regulatory T cell suppression of graft-versus-host disease
  Cameron McDonald-Hyman, James E. Muller, Michael Loschi, Govindarajan Thangavelu, Asim Saha, Sudha Kumari, Dawn K. Reichenbach, Michelle J. Smith, Guoan Zhang, Brent H...> ;The Journal of Clinical Investigation. 2018 Oct 1
• 54 citations
  Cutting Edge: TGF-β and Phosphatidylinositol 3-Kinase Signals Modulate Distinct Metabolism of Regulatory T Cell Subsets
  Bhavana Priyadharshini, Michael Loschi, Ryan H. Newton, Jian Wen Zhang, Kelsey K. Finn, Valerie A. Gerriets, Alexandria Huynh, Jeffrey C. Rathmell, Bruce R. Blazar, La...> ;Journal of Immunology. 2018 Sep 12
• 44 citations
  Maintenance of CD4 T cell fitness through regulation of Foxo1.
  Ryan H. Newton, Sharad Shrestha, Jenna M. Sullivan, K B Yates, Ewoud B. Compeer, Noga Ron-Harel, Bruce R. Blazar, Steven J. Bensinger, W N Haining, Michael L. Dustin, ...> ;Nature Immunology. 2018 Jul 9
• 25 citations
  Biomarkers of operational tolerance following kidney transplantation - The immune tolerance network studies of spontaneously tolerant kidney transplant recipients.
  Kenneth A. Newell, Andrew B. Adams, Laurence A. Turka> ;Human Immunology. 2018 May 1
• 16 citations
  Tumor Tolerance-Promoting Function of Regulatory T Cells Is Optimized by CD28, but Strictly Dependent on Calcineurin.
  Francesco Marangoni, Ruan Zhang, Vinidhra Mani, Martin Thelen, Noor J. Ali Akbar, Ross D. Warner, Tarmo Äijö, Valentina Zappulli, Gustavo J. Martinez, Laurence A. Turk...> ;Journal of Immunology. 2018 May 15
• Correction: B Cells Drive Autoimmunity in Mice with CD28-Deficient Regulatory T Cells.
  Ruan Zhang, Peter T. Sage, Kelsey K. Finn, Alexandria Huynh, Bruce R. Blazar, Francesco Marangoni, Thorsten R. Mempel, Arlene H. Sharpe, Laurence A. Turka> ;Journal of Immunology. 2018 Apr 1
• 35 citations
  Immunometabolism and PI(3)K Signaling As a Link between IL-2, Foxp3 Expression, and Suppressor Function in Regulatory T Cells
  Martin Fan, Laurence A. Turka> ;Frontiers in Immunology. 2018 Jan 29
• 6 citations
  Challenges and Opportunities for Biomarkers of Clinical Response to AHSCT in Autoimmunity.
  Kristina M. Harris, Tingting Lu, Noha Lim, Laurence A. Turka> ;Frontiers in Immunology. 2018 Feb 2
• Join now to see all

Journal Articles

• Maintenance of CD4 T Cell Fitness Through Regulation of Foxo1  
  Bruce R Blazar, Laurence A Turka, Nature