LaurieSusanConklinMD

PubMed

• 5 citations
  Pediatric Extrapolation of Adult Efficacy to Children Is Critical for Efficient and Successful Drug Development.
  Andrew E Mulberg, Laurie S Conklin, Nicholas M Croft> ;Gastroenterology. 2022 Jul 1
• 3 citations
  Early Inflammatory Markers are Associated With Inadequate Post-Induction Infliximab Trough in Pediatric Crohn's Disease
  Brad D Constant, Salina Khushal, Jiji Jiang, James E Bost, Ellen Chaisson, Laurie S. Conklin> ;Journal of Pediatric Gastroenterology and Nutrition. 2021 Mar 1
• 8 citations
  Exposure-Response Analysis of Vamorolone (VBP15) in Boys With Duchenne Muscular Dystrophy.
  Xiaonan Li, Laurie S. Conklin, John N. van den Anker, Eric P. Hoffman, Paula R. Clemens, William J. Jusko> ;Journal of Clinical Pharmacology. 2020 Oct 1
• 37 citations
  Efficacy and safety of vamorolone in Duchenne muscular dystrophy: An 18-month interim analysis of a non-randomized open-label extension study
  Edward C. Smith, Laurie S. Conklin, Eric P. Hoffman, Paula R. Clemens, Jean K. Mah, Richard S. Finkel, Michela Guglieri, Mar Tulinius, Yoram Nevo, Monique M. Ryan, Ric...> ;Plos Medicine. 2020 Sep 21
• 23 citations
  Serum miRNAs Are Pharmacodynamic Biomarkers Associated With Therapeutic Response in Pediatric Inflammatory Bowel Disease
  Suruchi K Batra, Christopher R. Heier, Lina Diaz-Calderon, Christopher B. Tully, Alyson A. Fiorillo, John N. van den Anker, Laurie S. Conklin> ;Inflammatory Bowel Diseases. 2020 Sep 18
• 17 citations
  Serum biomarkers associated with baseline clinical severity in young steroid-naïve Duchenne muscular dystrophy boys.
  Utkarsh J. Dang, Michael Ziemba, Paula R. Clemens, Yetrib Hathout, Laurie S. Conklin, Cinrg Vamorolone, Investigators, Eric P. Hoffman> ;Human Molecular Genetics. 2020 Aug 29
• 34 citations
  Designing clinical trials in paediatric inflammatory bowel diseases: a PIBDnet commentary.
  Dan Turner, Anne M. Griffiths, David C. Wilson, Diane R. Mould, Robert N. Baldassano, Richard K. Russell, Marla Dubinsky, Melvin B. Heyman, Lissy de Ridder, Jeffrey S....> ;Gut. 2020 Jan 1
• 58 citations
  Vamorolone trial in Duchenne muscular dystrophy shows dose-related improvement of muscle function.
  Eric P. Hoffman, Benjamin D Schwartz, Laurel J Mengle-Gaw, Edward C. Smith, Diana Castro, Jean K. Mah, Craig M. McDonald, Nancy L. Kuntz, Richard S. Finkel, Michela Gu...> ;Neurology. 2019 Sep 24
• 14 citations
  Developmental Pharmacodynamics and Modeling in Pediatric Drug Development.
  Laurie S. Conklin, Eric P. Hoffman, John N. van den Anker> ;Journal of Clinical Pharmacology. 2019 Sep 10
• 28 citations
  Disease-specific and glucocorticoid-responsive serum biomarkers for Duchenne Muscular Dystrophy.
  Yetrib Hathout, Chen Liang, Michael Olarewaju Ogundele, Ganggang Xu, Shefa M. Tawalbeh, Utkarsh J. Dang, Eric P. Hoffman, Heather Gordish-Dressman, Laurie S. Conklin, ...> ;Scientific Reports. 2019 Aug 21
• 4 citations
  Therapeutics for Inflammatory Bowel Diseases in Children and Adolescents: A Focus on Biologics and an Individualized Treatment Paradigm.
  Suruchi K Batra, Laurie S. Conklin> ;Handbook of Experimental Pharmacology. 2020 Jan 1
• 9 citations
  Population Pharmacokinetics of Vamorolone (VBP15) in Healthy Men and Boys With Duchenne Muscular Dystrophy.
  Panteleimon D. Mavroudis, John N. van den Anker, Laurie S. Conklin, Jesse M. Damsker, Eric P. Hoffman, Kanneboyina Nagaraju, Paula R. Clemens, William J. Jusko> ;Journal of Clinical Pharmacology. 2019 Jul 1
• 5 citations
  Pediatric Inflammatory Bowel Disease Clinical Innovations Meeting of the Crohn's & Colitis Foundation: Charting the Future of Pediatric IBD.
  Joseph A. Picoraro, Dale Lee, Caren Heller, Alandra Weaver, Jeffrey S. Hyams, Laurie S. Conklin, Anthony R. Otley, David Ziring, Subra Kugathasan, Joel R. Rosh, Andrew...> ;Inflammatory Bowel Diseases. 2019 Jan 1
• 19 citations
  Serum biomarkers of glucocorticoid response and safety in anti-neutrophil cytoplasmic antibody-associated vasculitis and juvenile dermatomyositis.
  Laurie S. Conklin, Peter A. Merkel, Lauren M. Pachman, Hemang Parikh, Shefa M. Tawalbeh, Jesse M. Damsker, David Cuthbertson, Gabrielle A. Morgan, Paul A. Monach, Yetr...> ;Steroids. 2018 Dec 1
• 58 citations
  Phase IIa trial in Duchenne muscular dystrophy shows vamorolone is a first-in-class dissociative steroidal anti-inflammatory drug.
  Laurie S. Conklin, Jesse M. Damsker, Eric P. Hoffman, William J. Jusko, Panteleimon D. Mavroudis, Benjamin D Schwartz, Laurel J Mengle-Gaw, Edward C. Smith, Jean K. Ma...> ;Pharmacological Research. 2018 Oct 1
• 15 citations
  Catheter-Related Venous Thrombosis in Hospitalized Pediatric Patients with Inflammatory Bowel Disease: Incidence, Characteristics, and Role of Anticoagulant Thrombopro...
  Carrie Diamond, Carole Hennessey, Jennifer Meldau, Christine Guelcher, Michael F. Guerrera, Laurie S. Conklin, Karun Sharma, Yaser Diab> ;The Journal of Pediatrics. 2018 Jul 1
• 16 citations
  Obesity and Pediatric Drug Development.
  Janelle D. Vaughns, Laurie S. Conklin, Ying Long, Panli Zheng, Fahim Faruque, Dionna J. Green, John N. van den Anker, Gilbert J. Burckart> ;Journal of Clinical Pharmacology. 2018 May 1
• 16 citations
  Position paper: The potential role of optical biopsy in the study and diagnosis of environmental enteric dysfunction
  Alexander J. Thompson, Michael Hughes, Salzitsa Anastasova, Laurie S. Conklin, Tudor Thomas, Cadman L. Leggett, William A. Faubion, Thomas J. Miller, Peter Delaney, Fr...> ;Nature Reviews. Gastroenterology & Hepatology. 2017 Nov 15
• 22 citations
  Enhanced TH17 Responses in Patients with IL10 Receptor Deficiency and Infantile-onset IBD.
  Griffith, A. E., Dror S. Shouval, Liza Konnikova, Alexandra Griffith, Sarah Wall, Amlan Biswas, Lael Werner, Moran Nunberg, Jochen Kammermeier, Jeremy A. Goettel, Rajs...> ;Inflammatory Bowel Diseases. 2017 Nov 1
• 5 citations
  Intravenous mesenchymal stromal cell therapy for inflammatory bowel disease: Lessons from the acute graft versus host disease experience.
  Laurie S. Conklin, Patrick J. Hanley, Jacques Galipeau, John Barrett, Catherine M. Bollard> ;Cytotherapy. 2017 Jun 1
• 42 citations
  Identification of Pathway-Specific Serum Biomarkers of Response to Glucocorticoid and Infliximab Treatment in Children with Inflammatory Bowel Disease.
  Christopher R. Heier, Alyson A. Fiorillo, Ellen Chaisson, Heather Gordish-Dressman, Yetrib Hathout, Jesse M. Damsker, Eric P. Hoffman, Laurie S. Conklin> ;Clinical and Translational Gastroenterology. 2016 Sep 15
• 34 citations
  Serum pharmacodynamic biomarkers for chronic corticosteroid treatment of children.
  Yetrib Hathout, Laurie S. Conklin, Haeri Seol, Heather Gordish-Dressman, Kristy J. Brown, Lauren P. Morgenroth, Kanneboyina Nagaraju, Christopher R. Heier, Jesse M. Da...> ;Scientific Reports. 2016 Aug 17
• 13 citations
  VBP15, a novel dissociative steroid compound, reduces NFκB-induced expression of inflammatory cytokines in vitro and symptoms of murine trinitrobenzene sulfonic acid-i...
  Jesse M. Damsker, Laurie S. Conklin, Soheil Sadri, Blythe C. Dillingham, Karuna Panchapakesan, Christopher R. Heier, John M. McCall, Anthony D. Sandler> ;Inflammation Research. 2016 Jun 3
• 3 citations
  Inflammatory bowel disease in sickle cell disease: Diagnostic and treatment challenges
  Justin M. Azar, Deepika S. Darbari, Emily Riehm Meier, Laurie S. Conklin, Anil Darbari> ;Journal of Pediatric Gastroenterology and Nutrition. 2014 Nov 1
• 376 citations
  Interleukin-10 Receptor Signaling in Innate Immune Cells Regulates Mucosal Immune Tolerance and Anti-Inflammatory Macrophage Function
  Dror S. Shouval, Amlan Biswas, Jeremy A. Goettel, Katelyn McCann, Evan Conaway, Naresh Singh Redhu, Ivan D. Mascanfroni, Ziad Al Adham, Sydney Lavoie, Mouna Ibourk, De...> ;Immunity. 2014 May 15
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Journal Articles

• Pediatric Inflammatory Bowel Disease Clinical Innovations Meeting of the Crohn’s & Colitis Foundation: Charting the Future of Pediatric IBD  
  Joel R Rosh, Athos Bousvaros, Laurie S Conklin, Caren A Heller, David Ziring, K T Park, Subra Kugathasan, Michael D Kappelman, Andrew B Grossman, Jeffrey S Hyams, Lee ..., Inflammatory Bowel Diseases

Lectures

• Children's National Medical Center : 22nd Annual Pediatric Board Review Course 
  Childrens National Medical Center, Bethesda, Maryland - 8/20/2012