LawrenceBAfrinMD

Oncology • Armonk, NY

Hematologic Oncology

Assoc. Prof. of Med., Medical University of South Carolina College of Medicine

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Office
99 Business Park Drive
Armonk, NY 10504
Phone+1 914-730-7390

Fax+1 914-730-7391
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Education & Training

Medical University of South CarolinaFellowship, Hematology and Medical Oncology, 1991 - 1995
Medical University of South CarolinaResidency, Internal Medicine, 1988 - 1991
Medical University of South CarolinaClass of 1988

Certifications & Licensure

MI State Medical License 2020 - 2026
FL State Medical License 2021 - 2025
NJ State Medical License 2020 - 2025
CT State Medical License 2017 - 2025
CA State Medical License 2021 - 2025
MN State Medical License 2014 - 2025
NY State Medical License 2017 - 2024
IL State Medical License 2020 - 2023
SC State Medical License 1989 - 2023
NC State Medical License 2020 - 2022
American Board of Internal Medicine Hematology
American Board of Internal Medicine Medical Oncology
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Publications & Presentations

PubMed

1 citations
Chemical Intolerance and Mast Cell Activation: A Suspicious Synchronicity.
Raymond F Palmer, Tania T Dempsey, Lawrence B Afrin> ;Journal of Xenobiotics. 2023 Nov 12
2 citations
Review of the role of the endogenous opioid and melanocortin systems in the restless legs syndrome.
Arthur S Walters, Yuqing Li, Brian B Koo, William G Ondo, Leonard B Weinstock, David Champion, Lawrence B Afrin, Elias G Karroum, Kanika Bagai, Karen Spruyt> ;Brain. 2024 Jan 4
Learned cautions regarding antibody testing in mast cell activation syndrome.
Lawrence B Afrin, Tania T Dempsey, Gerhard J Molderings> ;Diagnosis. 2023 Nov 1
4 citations
A survey of the currently known mast cell mediators with potential relevance for therapy of mast cell-induced symptoms.
Gerhard J Molderings, Lawrence B Afrin> ;Naunyn-Schmiedeberg's Archives of Pharmacology. 2023 Nov 1
Evaluation of a tryptase depletion index for better pathologic identification of mast cell activation syndrome.
Tomasz Zienkiewicz, Jürgen Homann, Martin Mücke, Holger Seidel, Hans-Jörg Hertfelder, Leonard B Weinstock, Lawrence B Afrin, Gerhard J Molderings> ;Zeitschrift Fur Gastroenterologie. 2023 Mar 1
1 citations
Exploring the role of the endogenous opiate system in the pathogenesis of anemia in an opiate receptor knock-out model of Restless Legs Syndrome.
Arthur S Walters, Yuqing Li, Elias G Karroum, David Champion, Leonard B Weinstock, Kanika Bagai, Lawrence B Afrin, Karen Spruyt> ;Medical Hypotheses. 2022 Oct 1
7 citations
Restless legs syndrome is associated with long-COVID in women.
Leonard B Weinstock, Jill B Brook, Arthur S Walters, Ashleigh Goris, Lawrence B Afrin, Gerhard J Molderings> ;Journal of Clinical Sleep Medicine. 2022 May 1
2 citations
Post-HPV-Vaccination Mast Cell Activation Syndrome: Possible Vaccine-Triggered Escalation of Undiagnosed Pre-Existing Mast Cell Disease?
Lawrence B Afrin, Tania T Dempsey, Leonard B Weinstock> ;Vaccines. 2022 Jan 16
4 citations
Safety and Efficacy of Ruxolitinib in Patients With Myelofibrosis and Low Platelet Counts (50–100 × 109/L): Final Analysis of an Open-label Phase 2 study
Moshe Talpaz, Josef T. Prchal, Lawrence B. Afrin, Murat O. Arcasoy, Solomon I. Hamburg, Jason Clark, Deanna Kornacki, Philomena Colucci, Srdan Verstovsek> ;Clinical Lymphoma, Myeloma & Leukemia. 2021 Nov 2
3 citations
Some cases of hypermobile Ehlers-Danlos syndrome may be rooted in mast cell activation syndrome.
Lawrence B. Afrin> ;American Journal of Medical Genetics. Part C, Seminars in Medical Genetics. 2021 Oct 31
60 citations
Mast cell activation symptoms are prevalent in Long-COVID.
Leonard B. Weinstock, Jill B Brook, Arthur S. Walters, Ashleigh J. Goris, Lawrence B. Afrin, Gerhard J. Molderings> ;International Journal of Infectious Diseases. 2021 Sep 23
8 citations
Effects of Primary Mast Cell Disease on Hemostasis and Erythropoiesis
Holger Seidel, H.-J. Hertfelder, Johannes Oldenburg, Johannes Kruppenbacher, Lawrence B. Afrin, Gerhard J. Molderings> ;International Journal of Molecular Sciences. 2021 Aug 20
172 citations
Covid-19 hyperinflammation and post-Covid-19 illness may be rooted in mast cell activation syndrome.
Lawrence B. Afrin, Leonard B. Weinstock, Gerhard J. Molderings> ;International Journal of Infectious Diseases. 2020 Nov 1
3 citations
Adrenal insufficiency is a contraindication for omalizumab therapy in mast cell activation disease: risk for serum sickness.
Gerhard J. Molderings, Franz Ludwig Dumoulin, Jürgen Homann, B. Sido, J. Textor, M. Mücke, G. J. Qagish, R. Barion, Martin Raithel, D. Klingmüller, V. S. Schäfer, H.-J...> ;Naunyn-Schmiedeberg's Archives of Pharmacology. 2020 May 6
28 citations
Mast Cell Activation Syndrome: A Primer for the Gastroenterologist
Leonard B. Weinstock, Laura A. Pace, Ali Rezaie, Lawrence B. Afrin, Gerhard J. Molderings> ;Digestive Diseases and Sciences. 2021 Apr 1
50 citations
Diagnosis of mast cell activation syndrome: a global "consensus-2".
Lawrence B. Afrin, Mary B. Ackerley, Linda S. Bluestein, Joseph H. Brewer, Jill B Brook, Ariana D. Buchanan, Jill R. Cuni, William Patrick Davey, Tania T. Dempsey, Sha...> ;Diagnosis. 2021 May 1
6 citations
Mast cell activation syndrome in pregnancy, delivery, postpartum and lactation: a narrative review.
Shanda R. Dorff, Lawrence B. Afrin> ;Journal of Obstetrics and Gynaecology. 2020 Mar 9
9 citations
Restless legs syndrome is associated with mast cell activation syndrome.
Leonard B. Weinstock, Arthur S. Walters, Jill B Brook, Zahid Kaleem, Lawrence B. Afrin, Gerhard J. Molderings> ;Journal of Clinical Sleep Medicine. 2020 Mar 15
7 citations
Recognition and Management of Medication Excipient Reactivity in Patients With Mast Cell Activation Syndrome.
Jill R. Schofield, Lawrence B. Afrin> ;The American Journal of the Medical Sciences. 2019 Jun 1
9 citations
Successful mast-cell-targeted treatment of chronic dyspareunia, vaginitis, and dysfunctional uterine bleeding
Lawrence B. Afrin, Tania T. Dempsey, Lila S. Rosenthal, Shanda R. Dorff> ;Journal of Obstetrics and Gynaecology. 2019 Apr 9
2 citations
The Significance of Mast Cell Activation in the Era of Precision Medicine.
Leonard B. Weinstock, Ali Rezaie, Lawrence B. Afrin> ;The American Journal of Gastroenterology. 2018 Nov 1
6 citations
Mast cell deposition and activation may be a new explanation for epiploic appendagitis.
Leonard B. Weinstock, Zahid Kaleem, Dale Selby, Lawrence B. Afrin> ;BMJ Case Reports. 2018 Sep 23
1 citations
Response to: "In reply to: 'Mast Cell Disorders in Ehlers-Danlos Syndrome' (Jaime Vengoechea, Department of Human Genetics, Emory University)".
Suranjith L. Seneviratne, Anne Maitland, Lawrence B. Afrin> ;American Journal of Medical Genetics. Part A. 2018 Jan 1
3 citations
Case Report: Treatment of systemic mastocytosis with sunitinib.
Gerhard J. Molderings, Lawrence B. Afrin, Hans-Jörg Hertfelder, Stefan Brettner> ;F1000research. 2017 Dec 28
30 citations
Risk of solid cancer in patients with mast cell activation syndrome: Results from Germany and USA.
Gerhard J. Molderings, Thomas Zienkiewicz, Jürgen Homann, Markus Menzen, Lawrence B. Afrin> ;F1000research. 2017 Oct 26
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