LeightonRolstonJamesMD

PubMed

• Liberation from Dialysis Dependence in a Patient with HIV-Associated Nephropathy (HIVAN) after Combined Antiretroviral Therapy (cART).
  Virin Rajiv Neil Ramoutar, Raafat Makary, Malleswari Ravi, Leighton R. James, Charles W. Heilig> ;Case Reports in Nephrology. 2020 Mar 15
• 10 citations
  Influence of Different Levels of Lipoic Acid Synthase Gene Expression on Diabetic Nephropathy
  Longquan Xu, Sylvia Hiller, Stephen W. Simington, Volker Nickeleit, Nobuyo Maeda, Leighton R. James, Xianwen Yi> ;Plos One. 2016 Oct 5
• 2 citations
  Tuberous Sclerosis and Bilateral Renal Angiomyolipomas: A Case Report and Literature Review of Emerging Treatment Strategies.
  Francois Jo-Hoy, Omar Tolaymat, Ryan Kunjal, Leighton R. James> ;Case Reports in Nephrology. 2016 Jul 25
• The bumpy lumpy kidney that dumped protein: granulomatous glomerular and tubulointerstitial nephritis
  Sharica M. Brookins, Claudia Ormenisan, Raafat Makary, Carmela Monteiro, Leighton R. James> ;Kidney International. 2015 Oct 1
• 3 citations
  Acute tubular necrosis (ATN) presenting with an unusually prolonged period of marked polyuria heralded by an abrupt oliguric phase.
  Virin Rajiv Neil Ramoutar, Cristian Landa, Leighton R. James> ;BMJ Case Reports. 2014 Aug 22
• 17 citations
  Connective tissue growth factor (CTGF) expression modulates response to high glucose.
  Leighton R. James, Catherine H. Le, Heather E. Doherty, Hyung Suk Kim, Nobuyo Maeda> ;Plos One. 2013 Aug 12
• Acute Kidney Injury due to Crescentic Glomerulonephritis in a Patient with Polycystic Kidney Disease.
  Reuben Maggard, Raafat Makary, Carmela L Monteiro, Leighton R. James> ;Case Reports in Nephrology and Urology. 2013 Jul 11
• 41 citations
  GLUT1 regulation of the pro-sclerotic mediators of diabetic nephropathy.
  Charles W. Heilig, Dilip K. Deb, Afu Abdul, Hasan Riaz, Leighton R. James, Jamal Salameh, N. Stanley Nahman> ;American Journal of Nephrology. 2013 Jun 26
• 24 citations
  Reduced expression of lipoic acid synthase accelerates diabetic nephropathy
  Xianwen Yi, Longquan Xu, Sylvia Hiller, Hyung Suk Kim, Volker Nickeleit, Leighton R. James, Nobuyo Maeda> ;Journal of the American Society of Nephrology. 2012 Jan 1
• 39 citations
  α-Lipoic acid protects diabetic apolipoprotein E-deficient mice from nephropathy.
  Xianwen Yi, Volker Nickeleit, Leighton R. James, Nobuyo Maeda> ;Journal of Diabetes and Its Complications. 2011 May 1
• 6 citations
  Influence of glucosamine on glomerular mesangial cell turnover: implications for hyperglycemia and hexosamine pathway flux
  Leighton R. James, Catherine H. Le, James W. Scholey> ;American Journal of Physiology. Endocrinology and Metabolism. 2010 Feb 1
• 18 citations
  Homocysteine-induced macrophage inflammatory protein-2 production by glomerular mesangial cells is mediated by PI3 kinase and p38 MAPK.
  Suresh Shastry, Leighton R. James> ;Journal of Inflammation. 2009 Sep 26
• 47 citations
  Kidney cysts, pancreatic cysts, and biliary disease in a mouse model of autosomal recessive polycystic kidney disease.
  Scott S. Williams, Patricia Cobo-Stark, Leighton R. James, Stefan Somlo, Peter Igarashi> ;Pediatric Nephrology. 2008 Feb 20
• 42 citations
  Homocysteine induces mesangial cell apoptosis via activation of p38-mitogen-activated protein kinase
  S. Shastry, Alistair J. Ingram, James W. Scholey, Leighton R. James> ;Kidney International. 2007 Feb 2
• 13 citations
  Lifelong genetic minipumps
  Kathleen M. Caron, Leighton R. James, Gene Lee, Hyung Suk Kim, Oliver Smithies> ;Physiological Genomics. 2005 Jan 20
• 39 citations
  Cardiac hypertrophy and sudden death in mice with a genetically clamped renin transgene
  Kathleen M. Caron, Leighton R. James, Hyung Suk Kim, Josh Knowles, Rick Uhlir, Lan Mao, John R. Hagaman, Wayne E. Cascio, Howard A. Rockman, Oliver Smithies> ;Proceedings of the National Academy of Sciences of the United States of America. 2004 Mar 2
• 58 citations
  A genetically clamped renin transgene for the induction of hypertension
  Kathleen M. Caron, Leighton R. James, Hyung Suk Kim, Scott G. Morham, Maria Luisa S. Sequeira Lopez, R. Ariel Gomez, Timothy L. Reudelhuber, Oliver Smithies> ;Proceedings of the National Academy of Sciences of the United States of America. 2002 Jun 11
• 134 citations
  Flux Through the Hexosamine Pathway Is a Determinant of Nuclear Factor κB– Dependent Promoter Activation
  Leighton R. James, Damu Tang, Alistair J. Ingram, Hao Ly, Kerri Thai, Lu Cai, James W. Scholey> ;Diabetes. 2002 Apr 1
• 26 citations
  Angiotensin II activates the GFAT promoter in mesangial cells.
  Leighton R. James, Alistair J. Ingram, Hao Ly, Kerri Thai, Lu Cai, James W. Scholey> ;American Journal of Physiology. Renal Physiology. 2001 Jul 1
• 34 citations
  Overexpression of GFAT activates PAI-1 promoter in mesangial cells
  Leighton R. James, I. George Fantus, Howard J. Goldberg, Hao Ly, James W. Scholey> ;American Journal of Physiology. Renal Physiology. 2000 Oct 1
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