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Lenora Epple, DO, Internal Medicine, Jefferson City, MO

Lenora Mae Epple DO


Physician

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  • 1705 Christy Dr.Jefferson City, MO 65101

  • Phone+1 573-616-0031

  • Fax+1 833-764-5034

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Summary

  • Dr. Lenora Epple, DO, MBA, is an internal medicine physician and founder of Focused Health & Wellness in Jefferson City, Missouri, where she provides personalized primary care and wellness through a thoughtful, relationship-based approach. Her work focuses on preventive medicine, lifestyle medicine, hormone health, and metabolic health, helping patients better understand their bodies and build sustainable strategies for long-term wellness.

    Dr. Epple completed her medical degree at Kansas City University of Medicine and Biosciences and her Internal Medicine residency at the University of Missouri.

    Prior to founding her practice, she served in multiple senior physician leadership roles within a large multi-state health system, including System Vice President of Patient Care Optimization, Regional President of a multi-site medical group, and Regional Vice President of Medical Affairs, where she functioned as Chief Medical Officer. In these roles, she led system-wide clinical initiatives, physician teams, population health strategies, quality and safety work, and care delivery across multiple hospitals and outpatient clinics, including during the COVID-19 pandemic.

    Her clinical interests include longevity, cardiovascular and cancer prevention, hormone balance, thyroid and brain health, and metabolic conditions such as prediabetes, diabetes, and weight management. She is also a writer and speaker focused on helping patients feel informed, empowered, and actively engaged in their care.

Education & Training

  • University of Missouri-Columbia
    University of Missouri-ColumbiaResidency, Internal Medicine, 2005 - 2008
  • Kansas City University of Medicine and Biosciences College of Osteopathic Medicine
    Kansas City University of Medicine and Biosciences College of Osteopathic MedicineClass of 2005

Certifications & Licensure

  • MO State Medical License
    MO State License 2008 - 2027

Press Mentions

  • Women's Symposium
    Women's SymposiumMarch 18th, 2026

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