LeonardLDragoneMD

PubMed

• Safety, antiviral activity and pharmacokinetics of JNJ-64530440, a novel capsid assembly modulator, as 4 week monotherapy in treatment-naive patients with chronic hepa...
  Ed J Gane, Christian Schwabe, Elina Berliba, Pisit Tangkijvanich, Alina Jucov, Nelea Ghicavii, Thierry Verbinnen, Oliver Lenz, Willem Talloen, Thomas N Kakuda, Chris W...> ;The Journal of Antimicrobial Chemotherapy. 2022 Mar 31
• 27 citations
  Murine trophoblast-derived and pregnancy-associated exosome-enriched extracellular vesicle microRNAs: Implications for placenta driven effects on maternal physiology
  Adrianne L. Stefanski, Nadine Martinez, Lisa K. Peterson, Tiffany J. Callahan, Eric Treacy, Marisa Luck, Samantha Friend, Amy Hermesch, Emin Maltepe, Tzu L. Phang, Leo...> ;Plos One. 2019 Feb 7
• 80 citations
  Peripheral Blood B Cell Depletion after Rituximab and Complete Response in Lupus Nephritis
  Liliana Michelle Gomez Mendez, Matthew D Cascino, J Garg, Tamiko R. Katsumoto, Paul Brakeman, Maria Dall'Era, R J Looney, Brad H. Rovin, Leonard Dragone, Paul Brunetta> ;Clinical Journal of the American Society of Nephrology. 2018 Oct 8
• 71 citations
  TCR signal strength controls thymic differentiation of iNKT cell subsets
  Kathryn D. Tuttle, S. Harsha Krovi, Jingjing Zhang, Romain Bedel, Laura Harmacek, Lisa K. Peterson, Leonard L. Dragone, Adam R. Lefferts, Catherine Halluszczak, Kent R...> ;Nature Communications. 2018 Jul 9
• 23 citations
  SLAP/SLAP2 prevent excessive platelet (hem)ITAM signaling in thrombosis and ischemic stroke in mice
  Deya Cherpokova, Markus Bender, Martina Morowski, Peter Kraft, Michael K. Schuhmann, Sarah M. Akbar, Cheryl S. Sultan, Craig E. Hughes, Christoph Kleinschnitz, Guido S...> ;Blood. 2015 Jan 1
• 8 citations
  Regulation of T cell receptor complex-mediated signaling by ubiquitin and ubiquitin-like modifications.
  Samantha Friend, Francina Deason-Towne, Lisa K. Peterson, Allison Berger, Leonard L. Dragone> ;American Journal of Clinical and Experimental Immunology. 2014 Dec 5
• 12 citations
  Choosing Wisely: the American College of Rheumatology's Top 5 for pediatric rheumatology.
  Kelly Rouster-Stevens, Stacy P. Ardoin, Ashley M. Cooper, Mara L. Becker, Leonard L. Dragone, Anna Huttenlocher, Karla B. Jones, Karen S. Kolba, L. Nandini Moorthy, Pe...> ;Arthritis Care & Research. 2014 May 1
• 33 citations
  Vaccine strain varicella-zoster virus–induced central nervous system vasculopathy as the presenting feature of DOCK8 deficiency
  Angela Sabry, Pia J. Hauk, Huie Jing, Helen C. Su, Nicholas V. Stence, David M. Mirsky, Maria A. Nagel, Jordan K. Abbott, Leonard L. Dragone, Jennifer Armstrong-Wells,...> ;The Journal of Allergy and Clinical Immunology. 2014 Apr 1
• 2 citations
  SLAP deficiency decreases dsDNA autoantibody production.
  Lisa K. Peterson, Luke F. Pennington, Laura A Shaw, Meredith Brown, Eric Treacy, Samantha Friend, Øyvind Hatlevik, Kira Rubtsova, Anatoly V. Rubtsov, Leonard L. Dragone> ;Clinical Immunology. 2014 Feb 1
• 15 citations
  LAPTM5 promotes lysosomal degradation of intracellular CD3ζ but not of cell surface CD3ζ.
  Yohei Kawai, Rika Ouchida, Sho Yamasaki, Leonard L. Dragone, Takeshi Tsubata, Ji-Yang Wang> ;Immunology and Cell Biology. 2014 Mar 18
• 11 citations
  The discovery of a reciprocal relationship between tyrosine-kinase signaling and cullin neddylation.
  Samantha Friend, Lisa K. Peterson, Eric Treacy, Adrianne L. Stefanski, Tomasz Sosinowski, Nathan D. Pennock, Allison Berger, Virginia D. Winn, Leonard L. Dragone> ;Plos One. 2013 Oct 4
• 6 citations
  SLAP deficiency increases TCR avidity leading to altered repertoire and negative selection of cognate antigen-specific CD8+ T cells
  Samantha Friend, Lisa K. Peterson, Ross M. Kedl, Leonard L. Dragone> ;Immunologic Research. 2013 Mar 1
• 1 citations
  Pregnancy amelioration of arthritis in SKG mice corresponds with alterations in serum amyloid A3 levels.
  Laura A Shaw, Adrianne L. Stefanski, Lisa K. Peterson, Kristen K. Rumer, Andrea Vondracek, Tzu L. Phang, Shimon Sakaguchi, Virginia D. Winn, Leonard L. Dragone> ;American Journal of Clinical and Experimental Immunology. 2012 Apr 20
• 25 citations
  The Src-Like Adaptor Protein Regulates GM-CSFR Signaling and Monocytic Dendritic Cell Maturation
  Larissa Liontos, Dilan Dissanayake, Pamela S. Ohashi, Arthur Weiss, Leonard L. Dragone, C. Jane McGlade> ;Journal of Immunology. 2011 Feb 15
• 13 citations
  SLAP Deficiency Enhances Number and Function of Regulatory T Cells Preventing Chronic Autoimmune Arthritis in SKG Mice
  Lisa K. Peterson, Laura A Shaw, Anthony Joetham, Shimon Sakaguchi, Erwin W. Gelfand, Leonard L. Dragone> ;Journal of Immunology. 2011 Feb 15
• 35 citations
  SLAP, a regulator of immunoreceptor ubiquitination, signaling, and trafficking.
  Leonard L. Dragone, Laura A Shaw, Margaret D. Myers, Arthur Weiss> ;Immunological Reviews. 2009 Nov 1
• 7 citations
  Novel method for quantitative ANA measurement using near-infrared imaging.
  Lisa K. Peterson, Daniel Wells, Laura A Shaw, Maria-Gabriela Velez, Ronald J. Harbeck, Leonard L. Dragone> ;Journal of Immunological Methods. 2009 Sep 30
• 33 citations
  The ubiquitin ligase Cbl-b limits Pseudomonas aeruginosa exotoxin T-mediated virulence
  Priya Balachandran, Leonard L. Dragone, Lynne Garrity-Ryan, Armando Lemus, Arthur Weiss, Joanne N. Engel> ;The Journal of Clinical Investigation. 2007 Feb 1
• 31 citations
  Src-like adaptor protein (SLAP) regulates B cell receptor levels in a c-Cbl-dependent manner
  Leonard L. Dragone, Margaret D. Myers, Carmen White, Shyam Gadwal, Tomasz Sosinowski, Hua Gu, Arthur Weiss> ;Proceedings of the National Academy of Sciences of the United States of America. 2006 Nov 28
• 32 citations
  SRC-like adaptor protein regulates B cell development and function.
  Leonard L. Dragone, Margaret D. Myers, Carmen White, Tomasz Sosinowski, Arthur Weiss> ;Journal of Immunology. 2006 Jan 1
• 77 citations
  Src-like adaptor protein regulates TCR expression on thymocytes by linking the ubiquitin ligase c-Cbl to the TCR complex.
  Margaret D. Myers, Tomasz Sosinowski, Leonard L. Dragone, Carmen White, Hamid Band, Hua Gu, Arthur Weiss> ;Nature Immunology. 2006 Jan 1
• 59 citations
  Src-like adaptor protein down-regulates T cell receptor (TCR)–CD3 expression by targeting TCRζ for degradation
  Margaret D. Myers, Leonard L. Dragone, Arthur Weiss> ;The Journal of Cell Biology. 2005 Jul 18
• 56 citations
  PTPRC (CD45) is not associated with the development of multiple sclerosis in U.S. patients.
  Lisa F. Barcellos, Stacy J. Caillier, Leonard L. Dragone, Melissa E. Elder, Eric Vittinghoff, P. Bucher, Robin R. Lincoln, Margaret A. Pericak-Vance, Jonathan L. Haine...> ;Nature Genetics. 2001 Sep 1
• 4 citations
  Expression of mouse CD43 in the B cell lineage of transgenic mice causes impaired immune responses to T-independent antigens.
  Julie R. Ostberg, Leonard L. Dragone, Melinda A. Borrello, Richard P. Phipps, Richard K. Barth, John G. Frelinger> ;European Journal of Immunology. 1997 Sep 1
• 19 citations
  Disregulated expression of CD43 (leukosialin, sialophorin) in the B cell lineage leads to immunodeficiency.
  J R Ostberg, Leonard L. Dragone, T Driskell, Jan A. Moynihan, Richard P. Phipps, Richard K. Barth, John G. Frelinger> ;Journal of Immunology. 1996 Dec 1
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Journal Articles

• Peripheral Blood B Cell Depletion After Rituximab and Complete Response in Lupus Nephritis  
  Matthew D Cascino, Jay Garg, Paul Brunetta, Tamiko R Katsumoto, Paul Brakeman, Brad Rovin, Leonard Dragone, Richard John Looney, Journal of the American Society of Nephrology