LeonardoAlonsoMD

PubMed

• 31 citations
  Amino Acid Metabolism Conflicts with Protein Diversity
  Teresa Krick, Nina Verstraete, Leonardo G. Alonso, David A. Shub, Diego U. Ferreiro, Michael Shub, Ignacio E. Sánchez> ;Molecular Biology and Evolution. 2014 Nov 1
• 17 citations
  Cysteine-Rich Positions Outside the Structural Zinc Motif of Human Papillomavirus E7 Provide Conformational Modulation and Suggest Functional Redox Roles
  Lucía B. Chemes, Gabriela Camporeale, Ignacio E. Sánchez, Gonzalo de Prat-Gay, Leonardo G. Alonso> ;Biochemistry. 2014 Mar 6
• 25 citations
  Sequence Evolution of the Intrinsically Disordered and Globular Domains of a Model Viral Oncoprotein
  Lucía B. Chemes, Juliana Glavina, Leonardo G. Alonso, Cristina Marino-Buslje, Gonzalo de Prat-Gay, Ignacio E. Sánchez> ;Plos One. 2012 Oct 31
• 12 citations
  Ordered Self-Assembly Mechanism of a Spherical Oncoprotein Oligomer Triggered by Zinc Removal and Stabilized by an Intrinsically Disordered Domain
  Clara Smal, Leonardo G. Alonso, Diana E. Wetzler, Angeles Heer> ;Plos One. 2012 May 9
• 6 citations
  Long-lasting immunoprotective and therapeutic effects of a hyperstable E7 oligomer based vaccine in a murine human papillomavirus tumor model†
  Maria Laura Cerutti, Leonardo G. Alonso, Silvio Tatti, Gonzalo de Prat-Gay> ;International Journal of Cancer. 2012 Apr 15
• 74 citations
  Circular dichroism techniques for the analysis of intrinsically disordered proteins and domains.
  Lucía B. Chemes, Leonardo G. Alonso, María G. Noval, Gonzalo de Prat-Gay> ;Methods in Molecular Biology. 2012 Jan 1
• 5 citations
  E6*, the 50 amino acid product of the most abundant spliced transcript of the e6 oncoprotein in high-risk human papillomavirus, is a promiscuous folder and binder.
  Angeles Heer, Leonardo G. Alonso, Gonzalo de Prat-Gay> ;Biochemistry. 2011 Feb 3
• 11 citations
  The human papillomavirus E7-E2 interaction mechanism in vitro reveals a finely tuned system for modulating available E7 and E2 proteins.
  Clara Smal, Diana E. Wetzler, Karina I. Dantur, Lucía B. Chemes, Maria Garcia-Alai, Mariano Dellarole, Leonardo G. Alonso, Kevin Gaston, Gonzalo de Prat-Gay> ;Biochemistry. 2009 Dec 22
• 23 citations
  Cytosolic accumulation of HPV16 E7 oligomers supports different transformation routes for the prototypic viral oncoprotein: The amyloid–cancer connection
  Karina I. Dantur, Leonardo G. Alonso, Eduardo M. Castaño, Laura Morelli, Juan Manuel Centeno-Crowley, Susana Vighi, Gonzalo de Prat-Gay> ;International Journal of Cancer. 2009 Oct 15
• 16 citations
  Folding of a dimeric beta-barrel: residual structure in the urea denatured state of the human papillomavirus E2 DNA binding domain.
  Y.K. Mok, Leonardo G. Alonso, L.M.T.R. Lima, Mark Bycroft, G. De Prat-Gay> ;Protein Science. 2008 Dec 31
• 32 citations
  The Catalytic Domain of Insulin-degrading Enzyme Forms a Denaturant-resistant Complex with Amyloid β Peptide IMPLICATIONS FOR ALZHEIMER DISEASE PATHOGENESIS
  Ramiro Esteban Llovera, Matias Blas de Tullio, Leonardo G. Alonso, Malcolm A. Leissring, Sergio B. Kaufman, Alex E. Roher, Laura Morelli, Eduardo M. Castaño> ;The Journal of Biological Chemistry. 2008 Jun 20
• 26 citations
  SPARC modulates the proliferation of stromal but not melanoma cells unless endogenous SPARC expression is downregulated
  Cynthia López Haber, Vanesa Gottifredi, Andrea S. Llera, Edgardo Salvatierra, Federico Prada, Leonardo G. Alonso, Sage E. Helene, Osvaldo L. Podhajcer> ;International Journal of Cancer. 2007 Dec 4
• 46 citations
  The N-terminal module of HPV16 E7 is an intrinsically disordered domain that confers conformational and recognition plasticity to the oncoprotein.
  Maria Garcia-Alai, Leonardo G. Alonso, Gonzalo de Prat-Gay> ;Biochemistry. 2007 Aug 23
• 15 citations
  Chaperone holdase activity of human papillomavirus E7 oncoprotein.
  Leonardo G. Alonso, Clara Smal, Maria Garcia-Alai, Lucía B. Chemes, Marcelo Salame, Gonzalo de Prat-Gay> ;Biochemistry. 2006 Jan 24
• 16 citations
  The Folding Mechanism of a Dimeric β-Barrel Domain
  Gonzalo de Prat-Gay, Alejandro D. Nadra, Fernando J. Corrales-Izquierdo, Leonardo G. Alonso, Diego U. Ferreiro, Yu-Keung Mok> ;Journal of Molecular Biology. 2005 Aug 19
• 22 citations
  Insulin-degrading enzyme degrades amyloid peptides associated with British and Danish familial dementia.
  Laura Morelli, Ramiro Esteban Llovera, Leonardo G. Alonso, Blas Frangione, Gonzalo de Prat-Gay, Jorge Ghiso, Eduardo M. Castaño> ;Biochemical and Biophysical Research Communications. 2005 Jul 8
• 45 citations
  The HPV16 E7 viral oncoprotein self-assembles into defined spherical oligomers.
  Leonardo G. Alonso, Maria Garcia-Alai, Clara Smal, Juan M. Centeno, Rubén Iacono, Eduardo Castaño, Peter Gualfetti, Gonzalo de Prat-Gay> ;Biochemistry. 2004 Mar 2
• 12 citations
  Specific Antibody-DNA Interaction: A Novel Strategy for Tight DNA Recognition
  Santiago M. Di Pietro, Juan M Centeno, M Laura Cerutti, M Fernanda Lodeiro, Diego U Ferreiro, Leonardo G Alonso, Frederick P. Schwarz, Fernando A. Goldbaum, Gonzalo de...> ;Biochemistry. 2003 May 27
• 123 citations
  UDP-Glc:glycoprotein glucosyltransferase recognizes structured and solvent accessible hydrophobic patches in molten globule-like folding intermediates.
  Julio J. Caramelo, Olga A. Castro, Leonardo G. Alonso, Gonzalo de Prat-Gay, Armando J. Parodi> ;Proceedings of the National Academy of Sciences of the United States of America. 2003 Jan 7
• 48 citations
  High-risk (HPV16) human papillomavirus E7 oncoprotein is highly stable and extended, with conformational transitions that could explain its multiple cellular binding p...
  Leonardo G. Alonso, Maria Garcia-Alai, Alejandro D. Nadra, Alicia N. Lapena, Fabio L. Almeida, Peter Gualfetti, Gonzalo de Prat-Gay> ;Biochemistry. 2002 Jul 25
• 31 citations
  Distinctive cognate sequence discrimination, bound DNA conformation, and binding modes in the E2 C-terminal domains from prototype human and bovine papillomaviruses.
  Diego U. Ferreiro, L. Mauricio T. R. Lima, Alejandro D. Nadra, Leonardo G. Alonso, Fernando A. Goldbaum> ;Biochemistry. 2000 Nov 28
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