
Leonardo V Riella MD PhD
Kidney & Pancreas Transplantation
Harold and Ellen Danser Endowed Chair in Transplantation at Massachusetts General Hospital, Harvard Medical School
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55 Fruit St.White-5-546CBoston, MA 02114
Phone+1 617-726-5277
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Summary
- Leonardo V. Riella, M.D. Ph.D. is the Harold and Ellen Danser Endowed Chair in Transplant Surgery at Harvard Medical School and the Medical Director of Kidney Transplantation at the Massachusetts General Hospital. Dr. Riella’s research is focused on understanding the mechanisms of immune regulation and on developing novel therapies to promote immune tolerance. In addressing kidney disease recurrence post-transplantation, I founded and lead the TANGO Consortium, the largest global effort dedicated to studying glomerular disease recurrence (www.tangoxstudy.com). His lab is also tackling the organ transplant shortage head-on by pioneering two extraordinary paths: bioengineering kidneys from human stem cells and turning to gene-modified pigs as potential kidney donors. These innovative approaches could drastically increase the availability of organs and transform the transplant landscape
Education & Training
- Mass General Brigham/Brigham and Women's Hospital/Massachusetts General HospitalFellowship, Nephrology, 2007 - 2011
- Mass General Brigham/Brigham and Women's HospitalResidency, Internal Medicine, 2004 - 2007
- Federal University of Parana Faculty of MedicineClass of 2003
Certifications & Licensure
- RI State Medical License 2021 - 2026
- MA State Medical License 2007 - 2025
- NH State Medical License 2021 - 2025
- American Board of Internal Medicine Internal Medicine
- American Board of Internal Medicine Nephrology
Awards, Honors, & Recognition
- BWH/MGH Teaching Faculty Award Brigham and Women's Hospital/Massachusetts General Hospital, 2020
- Department of Medicine Chair Research Award Brigham and Women's Hospital, 2019
- Bright Futures Prize Brigham and Women's Hospital, 2019
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Clinical Trials
- Efficacy and Safety of Eculizumab for Treatment of Antibody-mediated Rejection Following Renal Transplantation Start of enrollment: 2013 Nov 01
- Belatacept Conversion in Proteinuric Kidney Transplant Recipients Start of enrollment: 2015 Oct 01
- Conversion to Sirolimus: Effects in Cytomegalovirus Infection Recurrence Start of enrollment: 2015 Sep 01
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Publications & Presentations
PubMed
- Association of Kidney Graft Long-term Outcome With Recipient Cystathionine Gamma-lyase Polymorphisms and Hydrogen Sulfide Levels: A Cohort Study.Matthieu Halfon, Raffaella Emsley, Thomas Agius, Arnaud Lyon, Sébastien Déglise
Transplantation Direct. 2025-05-01 - Meeting Report: The Sixth International Sam Strober Workshop on Clinical Immune Tolerance.Helen Stark, Quan Yao Ho, Amy Cross, Alessandro Alessandrini, Alice Bertaina
Transplantation. 2025-04-01 - 1 citationsApplying Artificial Intelligence to Quantify Body Composition on Abdominal CTs and Better Predict Kidney Transplantation Wait-List Mortality.Karim Yatim, Guilherme T Ribas, Daniel C Elton, Marcio A B C Rockenbach, Ayman Al Jurdi
Journal of the American College of Radiology. 2025-03-01
Journal Articles
- Chronic Rejection of Human Face AllograftsLeonardo V Riella, Bohdan Pomahac, George F Murphy, Christine G Lian, Luccie Wo, American journal of transplantation
Authored Content
- Kidney Transplant iBookJune 2019
Press Mentions
- Bio-Engineered Kidney Transplant Offers Hope for MillionsApril 15th, 2025
- Thousands of Deceased Donor Kidneys Are Discarded. This Organization Hopes to Revive ThemApril 2nd, 2025
- How a Pig’s Kidney Gave a N.H. Man His Life BackMarch 7th, 2025
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Grant Support
- Role of Siglec-E in Regulating AlloimmunityMASSACHUSETTS GENERAL HOSPITAL2019–2025
- Significance of non-HLA antibodies in acute and chronic rejection of vascularized composite allograftsDepartment of Defense2019–Present
- Novel Role of Siglec-E Inhibitory Receptor in AlloimmunityNIH2019–2024
- Targeting Innate Immune Regulators to Reduce Rejection in Vascularized Composite Tissue TransplantsDepartment of Defense2020–2023
- Modulating donor dendritic cells in VCA transplantationDepartment of DefensePresent
- Biomarkers in VCA transplantationDepartment of DefensePresent
Committees
- Co-Chair, American Society of Transplantation Fellows Symposium 2016 - Present
- Co-Director of the AST Fellows Symposium, American Society of Transplantation 2016 - Present
Professional Memberships
- Fellow
Other Languages
- Italian, French, German, Portuguese, Spanish
Industry Relationships
- Investigator-initiated research, Bristols-Meyers-Squibb
External Links
- Personal Websitehttp://www.leoriella.com
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