LeslieM.TharenosMDMPH

Occupational Medicine • Saint Louis, MO

Principal Investigator

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Office
605 Old Ballas Rd Suite 220
Saint Louis, MO 63141
Phone+1 314-692-2100
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Summary

I am a board-certified Occupational and Preventive Medicine physician working as a Principal Investigator on Phase 2-4 clinical trials across multiple therapeutic areas, with a focus on vaccine development.

Education & Training

University of Illinois College of Medicine at Chicago Occupational MedicineResidency, Occupational Medicine, 2003 - 2005
University of IllinoisMPH, 2003 - 2005
St Louis University School of MedicineInternship, Transitional Year, 2001 - 2002
University of Missouri-Columbia School of MedicineClass of 2001

Certifications & Licensure

MO State Medical License 2003 - 2025
American Board of Preventive Medicine Occupational Medicine

Awards, Honors, & Recognition

Occupational Medicine Resident Research Award ACOEM, 2005

Clinical Trials

A Study to Evaluate ITCA 650 for the Treatment of Type 2 Diabetes Start of enrollment: 2013 Mar 01
Completed
Phase 3
Cardiovascular Outcomes Study of Naltrexone SR/Bupropion SR in Overweight and Obese Subjects With Cardiovascular Risk Factors (The Light Study) Start of enrollment: 2012 Jun 01
Terminated
Phase 3
An Open-label, Long-term, Safety Study of Lasmiditan for the Acute Treatment of Migraine Start of enrollment: 2015 Oct 07
Completed
Phase 3
Efficacy and Safety of Subcutaneous Administration of Fremanezumab (TEV-48125) for the Preventive Treatment of Migraine Start of enrollment: 2016 Feb 26
Completed
Phase 3
Naltrexone/Bupropion Cardiovascular Outcomes Study Start of enrollment: 2016 Jan 01
Terminated
Phase 4
Long-Term Safety and Efficacy Study of Fasinumab in Patients With Pain Due to Osteoarthritis (OA) of the Knee or Hip Start of enrollment: 2016 Feb 17
Completed
Phase 3
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Publications & Presentations

PubMed

Consistency of immunogenicity in three consecutive lots of a tetravalent dengue vaccine candidate (TAK-003): A randomized placebo-controlled trial in US adults.
Vianney Tricou, Peter J Winkle, Leslie M Tharenos, Martina Rauscher, Ian Escudero, Elaine Hoffman, Inge LeFevre, Astrid Borkowski, Derek Wallace> ;Vaccine. 2023 Nov 13
Bridging the immunogenicity of a tetravalent dengue vaccine (TAK-003) from children and adolescents to adults.
Inge LeFevre, Lulu Bravo, Nicolas Folschweiller, Eduardo Lopez Medina, Edson Duarte Moreira Jr, Francesco Nordio, Mayuri Sharma, Leslie M Tharenos, Vianney Tricou, Vee...> ;NPJ Vaccines. 2023 May 25
5 citations
Inverse association between rural environment in infancy and sensitization to rodents in adulthood
Samuel Dorevitch, Leslie Tharenos, Hakan Demirtas, Victoria Persky, James E. Artwohl, Jeffrey D Fortman> ;Annals of Allergy, Asthma & Immunology. 2007 May 1

Professional Memberships

American College of Occupational and Environmental Medicine - ACOEM
Member