LewisKaufmanMD

PubMed

• 7 citations
  SARS-CoV-2 viral protein ORF3A injures renal tubules by interacting with TRIM59 to induce STAT3 activation.
  Hong Cai, Ya Chen, Ye Feng, Morad Asadi, Lewis Kaufman, Kyung Lee, Thomas Kehrer, Lisa Miorin, Adolfo Garcia-Sastre, G Luca Gusella, Leyi Gu, Zhaohui Ni, Shan Mou, Joh...> ;Molecular Therapy. 2023 Mar 1
• 12 citations
  AMPK mediates regulation of glomerular volume and podocyte survival.
  Khadija Banu, Qisheng Lin, John M. Basgen, Marina Planoutene, Chengguo Wei, Anand C. Reghuvaran, Xuefei Tian, Hongmei Shi, Felipe Garzon, Aitor Garzia, Nicholas Chun, ...> ;JCI Insight. 2021 Oct 8
• 18 citations
  DACH1 protects podocytes from experimental diabetic injury and modulates PTIP-H3K4Me3 activity
  Aili Cao, Jianhua Li, Morad Asadi, John M. Basgen, Bingbing Zhu, Zhengzi Yi, Song Jiang, Tomohito Doke, Osama El Shamy, Niralee Patel, Paolo Cravedi, Evren U. Azeloglu...> ;The Journal of Clinical Investigation. 2021 May 17
• 39 citations
  Transcriptome-wide association analysis identifies DACH1 as a kidney disease risk gene that contributes to fibrosis
  Tomohito Doke, Shizheng Huang, Chengxiang Qiu, Hongbo Liu, Yuting Guan, Hailong Hu, Ziyuan Ma, Junnan Wu, Zhen Miao, Xin Sheng, Jianfu Zhou, Aili Cao, Jianhua Li, Lewi...> ;The Journal of Clinical Investigation. 2021 May 17
• 10 citations
  Disruption of MAGI2-RapGEF2-Rap1 signaling contributes to podocyte dysfunction in congenital nephrotic syndrome caused by mutations in MAGI2
  Bingbing Zhu, Aili Cao, Jianhua Li, James J. Young, Jenny Wong, Shazia Ashraf, Agnieszka Bierzynska, Madhav C. Menon, Steven Hou, Charles L. Sawyers, Kirk N. Campbell,...> ;Kidney International. 2019 Sep 1
• 11 citations
  SHROOM3-FYN Interaction Regulates Nephrin Phosphorylation and Affects Albuminuria in Allografts.
  Chengguo Wei, Khadija Banu, Felipe Garzon, John M. Basgen, Nimrod Philippe, Zhengzi Yi, Ruijie Liu, Jui Choudhuri, Miguel Fribourg, Tong Liu, Arun Cumpelik, Jenny Wong...> ;Journal of the American Society of Nephrology. 2018 Nov 1
• 73 citations
  Mutations in six nephrosis genes delineate a pathogenic pathway amenable to treatment.
  Shazia Ashraf, Hiroki Kudo, Jia Rao, Atsuo Kikuchi, Eugen Widmeier, Jennifer A. Lawson, Weizhen Tan, Tobias Hermle, Jillian K. Warejko, Shirlee Shril, Merlin Airik, Ti...> ;Nature Communications. 2018 May 17
• 24 citations
  The Hippo pathway regulator KIBRA promotes podocyte injury by inhibiting YAP signaling and disrupting actin cytoskeletal dynamics.
  Kristin Meliambro, Jenny Wong, Justina Ray, Rhodora Cristina Calizo, Sara Towne, Beatriz Cole, Fadi Salem, Ronald E. Gordon, Lewis Kaufman, John Cijiang He, Evren U. A...> ;The Journal of Biological Chemistry. 2017 Dec 22
• 14 citations
  MAGI-1 Interacts with Nephrin to Maintain Slit Diaphragm Structure through Enhanced Rap1 Activation in Podocytes
  Jie Ni, Sujin Bao, Ruth I. Johnson, Bingbing Zhu, Jianhua Li, Justin Vadaparampil, Christopher M. Smith, Kirk N. Campbell, Florian Grahammer, Tobias B. Huber, John Cij...> ;The Journal of Biological Chemistry. 2016 Nov 18
• 37 citations
  Podocyte-specific RAP1GAP expression contributes to focal segmental glomerulosclerosis–associated glomerular injury
  Uma Potla, Jie Ni, Justin Vadaparampil, Guozhe Yang, Jeremy S. Leventhal, Kirk N. Campbell, Peter Y. Chuang, Alexei Morozov, John Cijiang He, Vivette D. D'Agati, Paul ...> ;The Journal of Clinical Investigation. 2014 Apr 1
• 45 citations
  Essential role of poly(ADP-ribosyl)ation in cocaine action.
  Kimberly N. Scobie, Diane M. Damez-Werno, HaoSheng Sun, Ning-Yi Shao, Amy M. Gancarz, Clarisse Panganiban, Caroline Dias, Ja Wook Koo, Paola Caiafa, Lewis Kaufman, Rac...> ;Proceedings of the National Academy of Sciences of the United States of America. 2014 Feb 4
• 42 citations
  Podocyte-specific deletion of signal transducer and activator of transcription 3 attenuates nephrotoxic serum-induced glomerulonephritis
  Yan Dai, Leyi Gu, Weijie Yuan, Qing Yu, Zhaohui Ni, Michael W. Ross, Lewis Kaufman, Huabao Xiong, David J. Salant, John Cijiang He, Peter Y. Chuang> ;Kidney International. 2013 Nov 1
• 33 citations
  Deletion of podocyte STAT3 mitigates the entire spectrum of HIV-1-associated nephropathy.
  Leyi Gu, Yan Dai, Jin Xu, Sandeep K. Mallipattu, Lewis Kaufman, Paul E. Klotman, John Cijiang He, Peter Y. Chuang> ;AIDS. 2013 Apr 24
• 49 citations
  Expression of HIV Transgene Aggravates Kidney Injury in Diabetic Mice
  Sandeep K. Mallipattu, Ruijie Liu, Yifei Zhong, Edward Y. Chen, Vivette D. D'Agati, Lewis Kaufman, Avi Ma'ayan, Paul E. Klotman, Peter Y. Chuang, John Cijiang He> ;Kidney International. 2013 Apr 1
• 58 citations
  Role of the retinoic acid receptor-α in HIV-associated nephropathy
  Krishna Ratnam, Xiaobei Feng, Peter Y. Chuang, Vikram Verma, Ting-Chi Lu, Jinshan Wang, Yuanmeng Jin, Eduardo F. Farias, Joseph L. Napoli, Nan Chen, Lewis Kaufman, Tom...> ;Kidney International. 2011 Mar 2
• 28 citations
  Up-regulation of the Homophilic Adhesion Molecule Sidekick-1 in Podocytes Contributes to Glomerulosclerosis
  Lewis Kaufman, Uma Potla, Sarah Coleman, Stanislav Dikiy, Yutaka Hata, Hidetake Kurihara, John Cijiang He, Vivette D. D'Agati, Paul E. Klotman> ;The Journal of Biological Chemistry. 2010 Aug 13
• 17 citations
  The pathogenesis of HIV-associated nephropathy.
  Lewis Kaufman, Susan E. Collins, Paul E. Klotman> ;Advances in Chronic Kidney Disease. 2010 Jan 1
• 26 citations
  The homophilic adhesion molecule sidekick-1 contributes to augmented podocyte aggregation in HIV-associated nephropathy.
  Lewis Kaufman, Guozhe Yang, Kayo Hayashi, James R. Ashby, Li Huang, Michael W. Ross, Mary E. Klotman, Paul E. Klotman> ;FASEB Journal. 2007 May 1
• 62 citations
  HIV-1 infection initiates an inflammatory cascade in human renal tubular epithelial cells.
  Michael W. Ross, Cheng Fan, Michael D. Ross, Te Huatearina Chu, Yueyue Shi, Lewis Kaufman, Weijia Zhang, Mary E. Klotman, Paul E. Klotman> ;Journal of Acquired Immune Deficiency Syndromes. 2006 May 1
• 72 citations
  Role of Ubiquitin-Like Protein FAT10 in Epithelial Apoptosis in Renal Disease
  Michael W. Ross, Matthew Wosnitzer, Michael D. Ross, Benedetta Granelli, G. Luca Gusella, Mohammad Husain, Lewis Kaufman, Matthew P. Vasievich, Vivette D. D'Agati, Pat...> ;Journal of the American Society of Nephrology. 2006 Apr 1
• 18 citations
  Definition of the critical domains required for homophilic targeting of mouse sidekick molecules
  Kayo Hayashi, Lewis Kaufman, Michael W. Ross, Paul E. Klotman> ;FASEB Journal. 2005 Apr 1
• 30 citations
  Sidekick-1 Is Upregulated in Glomeruli in HIV-Associated Nephropathy
  Lewis Kaufman, Kayo Hayashi, Michael W. Ross, Michael D. Ross, Paul E. Klotman> ;Journal of the American Society of Nephrology. 2004 Jul 1
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