LindaMing-HueiLiauMDPhD, MBA

PubMed

• D-2-HG Inhibits IDH1mut Glioma Growth via FTO Inhibition and Resultant m6A Hypermethylation.
  Sean T Pianka, Tie Li, Terry J Prins, Blaine S C Eldred, Bryan M Kevan, Haowen Liang, Serendipity Zapanta Rinonos, Harley I Kornblum, David A Nathanson, Matteo Pellegr...> ;Cancer Research Communications. 2024 Mar 22
• Single-nucleus expression characterization of non-enhancing region of recurrent high-grade glioma.
  Kunal S Patel, Kaleab K Tessema, Riki Kawaguchi, Lindsey Dudley, Alvaro G Alvarado, Sree Deepthi Muthukrishnan, Travis Perryman, Akifumi Hagiwara, Vivek Swarup, Linda ...> ;Neuro-Oncology Advances. 2024 Jan 25
• dCas9/CRISPR-based methylation of O-6-methylguanine-DNA methyltransferase enhances chemosensitivity to temozolomide in malignant glioma.
  Serendipity Zapanta Rinonos, Tie Li, Sean Thomas Pianka, Terry J Prins, Blaine S C Eldred, Bryan M Kevan, Linda M Liau, Phioanh Leia Nghiemphu, Timothy F Cloughesy, Al...> ;Journal of Neuro-Oncology. 2024 Jan 1
• pH-Weighted amine chemical exchange saturation transfer echo planar imaging visualizes infiltrating glioblastoma cells.
  Kunal S Patel, Jingwen Yao, Nicholas S Cho, Francesco Sanvito, Kaleab Tessema, Alvaro Alvarado, Lindsey Dudley, Fausto Rodriguez, Richard Everson, Timothy F Cloughesy,...> ;Neuro-Oncology. 2024 Jan 5
• 4 citations
  Simultaneous quantification of perfusion, permeability, and leakage effects in brain gliomas using dynamic spin-and-gradient-echo echoplanar imaging MRI.
  Francesco Sanvito, Catalina Raymond, Nicholas S Cho, Jingwen Yao, Akifumi Hagiwara, Joey Orpilla, Linda M Liau, Richard G Everson, Phioanh L Nghiemphu, Albert Lai, Rob...> ;European Radiology. 2023 Oct 26
• Dendritic Cell Vaccination in Conjunction with a TLR Agonist Polarizes Interferon Immune Responses in Malignant Glioma Patients.
  Richard G Everson, Willy Hugo, Lu Sun, Joseph Antonios, Alexander Lee, Lizhong Ding, Melissa Bu, Sarah Khattab, Carolina Chavez, Emma Billingslea-Yoon, Andres Salazar,...> ;Research Square. 2023 Sep 12
• 1 citations
  Immune checkpoint blockade induces distinct alterations in the microenvironments of primary and metastatic brain tumors.
  Lu Sun, Jenny C Kienzler, Jeremy G Reynoso, Alexander Lee, Eileen Shiuan, Shanpeng Li, Jiyoon Kim, Lizhong Ding, Amber J Monteleone, Geoffrey C Owens, Joanna J Phillip...> ;The Journal of Clinical Investigation. 2023 Sep 1
• 3 citations
  Multi-nuclear sodium, diffusion, and perfusion MRI in human gliomas.
  Nicholas S Cho, Francesco Sanvito, Shruti Thakuria, Chencai Wang, Akifumi Hagiwara, Raksha Nagaraj, Sonoko Oshima, Alfredo L Lopez Kolkovsky, Jianwen Lu, Catalina Raym...> ;Journal of Neuro-Oncology. 2023 Jun 1
• 1 citations
  External Control Arms and Data Analysis Methods in Nonrandomized Trial of Patients With Glioblastoma-Reply.
  Linda M Liau, Keyoumars Ashkan, Marnix L Bosch> ;JAMA Oncology. 2023 Jul 1
• 1 citations
  Assessment of treatment response to dendritic cell vaccine in patients with glioblastoma using a multiparametric MRI-based prediction model.
  Laiz Laura de Godoy, Sanjeev Chawla, Steven Brem, Sumei Wang, Donald M O'Rourke, MacLean P Nasrallah, Arati Desai, Laurie A Loevner, Linda M Liau, Suyash Mohan> ;Journal of Neuro-Oncology. 2023 May 1
• A single-institution retrospective analysis of pathologically determined malignant transformation inmutant glioma patients.
  Vicki Liu, Ethan A Wetzel, Blaine S C Eldred, Serendipity Zapanta Rinonos, Terry J Prins, Negar Khanlou, Linda M Liau, Robert Chong, Phioanh L Nghiemphu, Timothy F Clo...> ;Neuro-Oncology Advances. 2023 Apr 11
• Retrospective examination of pseudoprogression inmutant gliomas.
  Ethan A Wetzel, Matthew J Farrell, Blaine S C Eldred, Vicki Liu, Ishan Saha, Serendipity Zapanta Rinonos, Terry Prins, Tie Li, Minsong Cao, John Hegde, Tania Kaprealia...> ;Neuro-Oncology Advances. 2023 Mar 18
• 1 citations
  Targeted Public Health Training for Neurosurgeons: An Essential Task for the Prioritization of Neurosurgery in the Evolving Global Health Landscape.
  Michael J Strong, Karin Murazsko, Anil Nanda, Linda Liau, Gail Rosseau, Rallo, M., Michael S Rallo, Zoe E Teton> ;Neurosurgery. 2023 Jan 1
• 117 citations
  Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A P...
  Linda M Liau, Keyoumars Ashkan, Steven Brem, Jian L Campian, John E Trusheim, Fabio M Iwamoto, David D Tran, George Ansstas, Charles S Cobbs, Jason A Heth, Michael E S...> ;JAMA Oncology. 2023 Jan 1
• 6 citations
  A molecular interactome of the glioblastoma perivascular niche reveals integrin binding sialoprotein as a mediator of tumor cell migration.
  Yasmin Ghochani, Sree Deepthi Muthukrishnan, Alireza Sohrabi, Riki Kawaguchi, Michael C Condro, Soniya Bastola, Fuying Gao, Yue Qin, Jack Mottahedeh, M Luisa Iruela-Ar...> ;Cell Reports. 2022 Oct 18
• 2 citations
  Relapse patterns and radiation dose exposure in IDH wild-type glioblastoma at first radiographic recurrence following chemoradiation.
  Satoka Shidoh, Ricky R Savjani, Nicholas S Cho, Henrik E Ullman, Akifumi Hagiwara, Catalina Raymond, Albert Lai, Phionah L Nghiemphu, Linda M Liau, Whitney B Pope, Tim...> ;Journal of Neuro-Oncology. 2022 Oct 1
• 7 citations
  Amine-weighted chemical exchange saturation transfer magnetic resonance imaging in brain tumors.
  Nicholas S Cho, Akifumi Hagiwara, Jingwen Yao, David A Nathanson, Robert M Prins, Chencai Wang, Catalina Raymond, Brandon R Desousa, Ajit Divakaruni, Danielle H Morrow...> ;NMR in Biomedicine. 2023 Jun 1
• 9 citations
  Diversity in Neurosurgical Recruitment and Training in the United States: A Systematic Review.
  Andrew Wang, Nathan A Shlobin, Jasmine A T DiCesare, Langston T Holly, Linda M Liau> ;World Neurosurgery. 2022 Jun 1
• 2 citations
  Diffusion MRI is an early biomarker of overall survival benefit in IDH wild-type recurrent glioblastoma treated with immune checkpoint inhibitors.
  Akifumi Hagiwara, Talia C Oughourlian, Nicholas S Cho, Jacob Schlossman, Chencai Wang, Jingwen Yao, Catalina Raymond, Richard Everson, Kunal Patel, Sergey Mareninov, F...> ;Neuro-Oncology. 2022 Jun 1
• 2 citations
  Diagnostic and Prognostic Value of pH- and Oxygen-Sensitive Magnetic Resonance Imaging in Glioma: A Retrospective Study.
  Jingwen Yao, Akifumi Hagiwara, Talia C Oughourlian, Chencai Wang, Catalina Raymond, Whitney B Pope, Noriko Salamon, Albert Lai, Matthew Ji, Phioanh L Nghiemphu, Linda ...> ;Cancers. 2022 May 20
• 6 citations
  Prognostic value of-methylguanine-DNA methyltransferase methylation in isocitrate dehydrogenase mutant gliomas.
  Keng Lam, Blaine S C Eldred, Bryan Kevan, Sean Pianka, Brittany A Eldred, Serendipity Zapanta Rinonos, William H Yong, Linda M Liau, Phioanh L Nghiemphu, Timothy F Clo...> ;Neuro-Oncology Advances. 2022 Mar 1
• 20 citations
  Human Astrocytes Exhibit Tumor Microenvironment-, Age-, and Sex-Related Transcriptomic Signatures.
  Mitchell C Krawczyk, Jillian R Haney, Lin Pan, Christine Caneda, Rana R Khankan, Samuel D Reyes, Julia W Chang, Marco Morselli, Harry V Vinters, Anthony C Wang, Inma C...> ;The Journal of Neuroscience. 2022 Feb 23
• 6 citations
  Visualization of tumor heterogeneity and prediction of isocitrate dehydrogenase mutation status for human gliomas using multiparametric physiologic and metabolic MRI.
  Akifumi Hagiwara, Hiroyuki Tatekawa, Jingwen Yao, Catalina Raymond, Richard Everson, Kunal Patel, Sergey Mareninov, William H Yong, Noriko Salamon, Whitney B Pope, Phi...> ;Scientific Reports. 2022 Jan 20
• 1 citations
  Paradoxical Association Between Relative Cerebral Blood Volume Dynamics Following Chemoradiation and Increased Progression-Free Survival in Newly Diagnosed IDH Wild-Ty...
  Jodi Goldman, Akifumi Hagiwara, Jingwen Yao, Catalina Raymond, Christian Ong, Rojin Bakhti, Elizabeth Kwon, Maguy Farhat, Carlo Torres, Lily G Erickson, Brandon J Curl...> ;Frontiers in Oncology. 2022 Jan 1
• 83 citations
  Neoadjuvant PD-1 blockade induces T cell and cDC1 activation but fails to overcome the immunosuppressive tumor associated macrophages in recurrent glioblastoma
  Alexander Lee, Lu Sun, Aaron Mochizuki, Jeremy Reynoso, Joey Orpilla, Frances Chow, Jenny Kienzler, Richard Everson, David Nathanson, Steven J. Bensinger, Linda M. Lia...> ;Nature Communications. 2021 Nov 26
• Join now to see all

Journal Articles

• Heterogeneity Within the PF-EPN-B Ependymoma Subgroup  
  Andrew Grossbach, Vijay Ramaswamy, Benjamin Lu, Mariarita Santi, Caterina Giannini, Linda M Liau, Terri S Armstrong, Sarah Leary, Matthias A Karajannis, Kenneth Aldape..., Acta Neuropathologica
• Immunosuppressive tumor-infiltrating myeloid cells mediate adaptive immune resistance via a PD-1/PD-L1 mechanism in glioblastoma  
  Antonios JP, Soto H, Everson RG, Moughon D, Orpilla JR, Shin NP, Sedighim S, Treger J, Odesa S, Tucker A, Yong WH, Li G, Cloughesy TF, Liau LM, Prins RM, Neuro Oncol, 1/1/2017
• Incidence, survival, pathology, and genetics of adult Latino Americans with glioblastoma  
  Shabihkhani M, Telesca D, Movassaghi M, Naeini YB, Hojat SA, Gupta D, Lucey GM, Ontiveros M, Wang MW, Hanna LS, Sanchez DE, Mareninov S, Khanlou N, Vinters HV, Bergsne..., J Neurooncol, 1/1/2017
• Detection of wild-type EGFR amplification and EGFRvIII mutation in CSF-derived extracellular vesicles of glioblastoma patients  
  Figueroa JM, Skog J, Akers J, Li H, Komotar R, Jensen R, Ringel F, Yang I, Kalkanis S, Thompson R, LoGuidice L, Berghoff E, Parsa A, Liau LM, Curry W, Cahill D, Betteg..., Neuro Oncol, 1/1/2017
• Perfusion and diffusion MRI signatures in histologic and genetic subtypes of WHO grade II-III diffuse gliomas  
  Leu K, Ott GA, Lai A, Nghiemphu PL, Pope WB, Yong WH, Liau LM, Cloughesy TF, Ellingson BM, J Neurooncol, 1/1/2017
• Early experience with formalin-fixed paraffin-embedded (FFPE) based commercial clinical genomic profiling of gliomas – robust and informative with caveats  
  Movassaghi M, Shabihkhani M, Hojat SA, Williams RR, Chung LK, Im K, Lucey GM, Wei B, Mareninov S, Wang MW, Ng DW, Tashjian RS, Magaki S, Perez-Rosendahl M, Yang I, Kha..., Exp Mol Pathol, 1/1/2017
• The whole-genome landscape of medulloblastoma subtypes  
  Northcott PA, Buchhalter I, Morrissy AS,… Liau LM, Mora J, McLendon RE, Jabado N, Kumabe T, Chuah E, Ma Y, Moore RA, Mungall AJ, Mungall KL, Thiessen N, Tse K, Wong T..., Nature, 1/1/2017
• Detection of immune responses after immunotherapy in glioblastoma using PET and MRI  
  Antonios JP, Soto H, Everson RG, Moughon DL, Wang AC, Orpilla J, Radu C, Ellingson BM, Lee JT, Cloughesy T, Phelps ME, Czernin J, Liau LM, Prins RM, Proc Natl Acad Sci USA, 1/1/2017
• Tissue microarray analysis for epithelial membrane protein-2 as a novel biomarker for gliomas  
  Chung LK, Pelargos PE, Chan AM, Demos JV, Lagman C, Sheppard JP, Nguyen T, Chang YL, Hojat SA, Prins RM, Liau LM, Nghiemphu PL, Lai A, Cloughesy TF, Yong, WH, Gordon L..., Brain Tumor Pathol, 1/1/2017
• The aging neurosurgeon: When is enough, enough? Attitudes toward ceasing practice and testing in late career  
  Babu MA, Liau LM, Spinner RJ, Meyer FB, Mayo Clin Proc, 1/1/2017
• TCR sequencing can identify and track glioma-infiltrating T cells after DC vaccination  
  Hsu M, Sedighim S, Wang T, Antonios JP, Everson RG, Tucker AM, Du L, Emerson R, Yusko E, Sanders C, Robins H, Yong WH, Davidson TB, Li G, Liau LM, Prins RM, Cancer Immunol Res, 1/1/2016
• Contrast-enhancing tumor growth dynamics of pre-operative, treatment-naïve human glioblastoma  
  Ellingson BM, Nguyen HN, Lai A, Nechifor RE, Zaw O, Pope WB, Yong WH, Nghiemphu PL, Liau LM, Cloughesy TF, Cancer, 1/1/2016
• Improved leakage correction for single-echo dynamic susceptibility contrast perfusion MRI estimates of relative blood volume in high-grade gliomas by accounting for bi...  
  Leu K, Boxerman JL, Cloughesy TF, Lai A, Nghiemphu PL, Liau LM, Pope WB, Ellingson BM, Am J Neuroradiol, 1/1/2016
• Large-scale assessment of the gliomasphere model system  
  Laks DR, Crisman TJ, Shih MY, Mottahedeh J, Gao F, Sperry J, Garrett MC, Yong WH, Cloughesy TF, Liau LM, Lai A, Coppola G, Kornblum HI, Neuro Oncol, 1/1/2016
• Phase I trial of vocimagene amiretrorepvec and 5-fluorocystosine for recurrent high-grade glioma  
  Cloughesy TF, Landolfi J, Hogan DJ, Bloomfield S, Carter B, Chen CC, Elder JB, Kalkanis SN, Kesari S, Lai A, Lee IY, Liau LM, Mikkelsen T, Nghiemphu PL, Piccioni D, Wa..., Sci Transl Med, 1/1/2016
• Therapeutic impact of cytoreductive surgery and irradiation of posterior fossa ependymoma in the molecular era: a retrospective multi-cohort analysis  
  Ramaswamy V, Hielscher T, Mack SC,… Liau LM, Everson R, Grossbach A, Shalaby T, Grotzer M, Karajannis MA, Zagzag D, Wheeler H, von Hoff K, Alonso MM, Tunon T, Schulle..., J Clin Oncol, 1/1/2016
• Maintenance of certification and the aging neurosurgeon  
  Babu MA, Liau LM, Spinner RJ, Meyer FB, Neurosurgery, 1/1/2016
• PD-1 blockade enhances the vaccination-induced immune response in glioma  
  Antonios JP, Soto H, Everson RG, Orpilla J, Moughon D, Shin N, Sedighim S, Yong WH, Li G, Cloughesy TF, Liau LM, Prins RM, JCI Insight, 1/1/2016
• Simulation phantom validation and clinical evaluation of fast pH-weighted molecular imaging using amine chemical exchange saturation transfer echo planar imaging (CEST...  
  Harris RJ, Cloughesy TF, Liau LM, Nghiemphu PL, Lai A, Pope WB, Ellingson BM, NMR Biomed, 1/1/2016
• Human TERT promoter mutation enables survival advantage from MGMT promoter methylation on IDH1 wild-type primary glioblastoma treated by standard chemoradiotherapy  
  Nguyen HN, Lie A, Li T, Chowdhury R, Liu F, Ozer B, Wei B, Green RM, Ellingson BM, Wang HJ, Elashoff R, Liau LM, Yong WH, Nghiemphu PL, Cloughesy T, Lai A, Neuro Oncol, 1/1/2016
• Multiple calcifying pseudoneoplasms of the neuraxis (MCAPNON): Distinct entity, CAPNON variant, or old neurocysticercosis?  
  Abdaljaleel M, Mazumder R, Patel CB, Im K, Pope W, Liau LM, Vinters HV, Yong WH, Neuropathology, 1/1/2016
• Radial mobility and cytotoxic function of retroviral replicating vector transduced, non-adherent alloresponsive T lymphocytes  
  Erickson KL, Hickey MJ, Kato Y, Malone CC, Owens GC, Prins RM, Liau LM, Kasahara N, Kruse CA, J Vis Exp, 1/1/2015
• Relationship between [18F]FDOPA-PET uptake, apparent diffusion coefficient (ADC), and proliferation rate in recurrent malignant gliomas  
  Karavaeva E, Harris RJ, Leu K, Shabihkhani M, Yong WH, Pope WB, Lai A, Nghiemphu PL, Liau LM, Chen W, Czernin J, Cloughesy TF, Ellingson BM, Mol Imaging Biol, 1/1/2015
• MRI perfusion measurements calculated using advanced deconvolution techniques predict survival in recurrent gliolastoma treated with bevacizumab  
  Harris RJ, Cloughesy TF, Hardy AJ, Liau LM, Pope WB, Nghiemphu PL, Lai A, Ellingson BM, J Neurooncol, 1/1/2015
• Dendritic cell immunotherapy for brain tumors  
  Antonios JP, Everson RG, Liau LM, J Neurooncol, 1/1/2015
• Join now to see all

Books/Book Chapters

• Neurophotonics and Brain Mapping 
  Chapter: Spectro-Temporal Autofluorescence Contrast-Based Imaging for Brain Tumor Margin Detection and Biobanking 
  Page 355 - 368Papour A, Taylor Z, Liau LM, Yong WH, Stafsudd O, Grundfest WSEditors: Chen Y & Kateb B.CRC Press2017
• Translational Immunotherapy for Brain Tumors 
  Chapter: Dendritic Cell Therapy for Brain Tumors 
  Everson RG, Antonios JP, Tucker AM, Liau LMEditors: Sampson JS.Elsevier, Inc2017
• Intracranial Gliomas. Part III – Innovative Treatment Modalities 
  Chapter: Cell-Based Immunotherapy of Gliomas 
  Page 90 - 100Everson RG, Antonios JP, Liau LMEditors: Chernov MF, Muragaki Y, Kesari S, McCutcheon IE.Karger2017
• Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, & Immunotherapy 
  Chapter: Overview of Dendritic Cell Vaccine Therapy in Brain Tumors 
  Everson RG, Liau LMEditors: Newton HB.Elsevier, IncEdition 2nd,2017
• Frontiers in Cancer Immunology 
  Chapter: Genetically-engineered T-cell Immunotherapy for Gliomas and Other Solid Tumors 
  Page 105 - 122Everson RG, Malone CC, Erickson KL, Fomchenko EI, Prins RM, Liau LM, Kruse CAEditors: Song J.Bentham Scientific Publishers2015
• Neuro-Oncology: The Essentials 
  Chapter: Malignant Gliomas 
  Everson R & Liau LMEditors: Bernstein M & Berger MS.Thieme Medical Publishers, New York, NYEdition 3rd,2014
• Pediatric Cancer 
  Chapter: Pediatric Medulloblastoma: Pituitary adenylyl cyclase activating peptide/protein kinase A antagonism of hedgehog signaling 
  Cohen JR, Liau LM, and Waschek JAEditors: Hayat MA.Springer, New York, NY2012
• Radiation Medicine Rounds 
  Chapter: Immunotherapy for Malignant Gliomas 
  Everson R, Fomchenko E, Foulad D, Lisiero DN, Liau LMEditors: Chakravarti A.Demos Medical, New York, NY2012
• CNS Cancer: Models, Markers, Prognostic Factors, Targets, and Therapeutic Approaches 
  Chapter: Harnessing T-cell immunity to target brain tumors 
  Walker PR, Prins RM, Dietrich PY, and Liau LMEditors: van Meir EG.Springer, New York, NY2009
• Youmans Neurological Surgery 
  Chapter: Intraoperative MRI 
  Kim W and Liau LMEditors: Winn HR.Elsevier, Philadelphia, PAEdition 6th,2009
• Neurosurgical Operative Atlas 
  Chapter: Intraoperative Magnetic Resonance Imaging for Brain Tumor Resection 
  Bergsneider M and Liau LMEditors: Badie B.Thieme, New York, NYEdition 2nd,2006
• Genomic and Molecular Neuro-Oncolgoy 
  Chapter: Therapeutic Targeting of Molecular Pathways that Induce Brain Tumor Development 
  Van Meir EG, Hao C, Post DE, Liau LM, and Brat DJEditors: Zhang W and Fuller GN.Jones and Bartlett Publishers, Boston, MA2003
• Brain Tumor Immunotherapy 
  Page 1 - 373Editors: Liau LM, Becker DP, Cloughesy TF, and Bigner DD.Humana Press, Totowa, NJ2001
• Brain Tumor Immunotherapy 
  Chapter: Dendritic Cell Immunotherapy for Brain Tumors 
  Vandenabeele S, Liau LM, and Ashley DEditors: Liau LM et. al.Humana Press, Totowa, NJ2001
• Cancer Treatment 
  Chapter: Brain 
  Cloughesy TF, Selch MT, and Liau LMEditors: Haskell CM et. al.W.B. Saunders Company, Philadelphia, PAEdition 5th,2001
• Neurological Surgery 
  Chapter: Pathology and Pathophysiology of Head Injury 
  Liau LM, Bergsneider M, and Becker DPEditors: Youmans J.W.B. Saunders Company, Philadelphia, PAEdition 4th,1995
• Join now to see all

Abstracts/Posters

• TCR sequencing can identify and track tumor-specific T-cell populations and is a predictive biomarker of response to DC vaccination in glioblastoma patients
  Sedighim S, Hsu M, Wang T, Everson RG, Tucker A, Antonios JP, Du L, Emerson R, Yusko E, Sanders C, Robins H, Yong W, Davidson TB, Li G, Liau LM, Prins RM, 107th American Association for Cancer Research (AACR) Annual Meeting, Cancer Research, New Orleans, LA, 1/1/2016
• Study of 82 glioblastoma autopsies including subset evaluation of PD-1 and PDL-1
  Abdaljaleel M, Movassaghi M, Tashjian RS,... Liau LM, Yong WH, 92nd Annual Meeting of the American Association of Neuropathologists, Baltimore, MD, 1/1/2016
• The Toca 7 study: Phase IB study of Toca511, a live gama retrovirus, and Toca FC, an extended-release formulation of 5-fluorocytosine combined with standard of care in...
  Vogelbaum MA, Lassman AB, Lee I,… Liau LM…, Cloughesy TF, 21st Annual Meeting of the Society for Neuro-Oncology, Neuro-Oncol, Phoenix, AZ, 1/1/2016
• Successful cancer-selective gene delivery following intravenous Toca511 delivery in patients with recurrent high-grade glioma
  Cloughesy TF, Walbert T, Bota DA,… Liau LM,… Kalkanis SN, 21st Annual Meeting of the Society for Neuro-Oncology, Neuro-Oncol, Phoenix, AZ, 1/1/2016
• Complementary clinical and ancillary data from 123 patients with recurrent high-grade glioma from three Phase I trials of Toca511 and Toca FC
  Aghi MK, Vogelbaum MA, Kalkanis SN,… Liau LM,… Cloughesy TF, 21st Annual Meeting of the Society for Neuro-Oncology, Neuro-Oncol, Phoenix, AZ, 1/1/2016
• PD-1 expression by tumor infiltrating lymphocytes in glioblastoma is a marker of both activation and exhaustion
  Davidson TB, Hsu M, Sedighim S,… Liau LM, Prins RM, 21st Annual Meeting of the Society for Neuro-Oncology, Neuro-Oncol, Phoenix, AZ, 1/1/2016
• Phase IIA clinical trial evaluating dendritic cell vaccine for the treatment of low-grade gliomas
  Moughon DL, Everson R, Odesa SK,… Liau LM, 21st Annual Meeting of the Society for Neuro-Oncology, Neuro-Oncol, Phoenix, AZ, 1/1/2016
• Simultaneous quantitative pH mapping and hypoxia imaging using fast multi-echo amine CEST-EPI in human gliomas
  Harris R, Liau LM, Leu K,.... Ellingson B, 21st Annual Meeting of the Society for Neuro-Oncology, Neuro-Oncol, Phoenix, AZ, 1/1/2016
• Patterns from dynamic vessel size imaging of arterial and venous perfusion correlates with aggressiveness and stratifies 1p19q co-deleted from non-codeleted low-grade ...
  Leu K, Cloughesy TF, Liau LM,… Ellingson B, 21st Annual Meeting of the Society for Neuro-Oncology, Neuro-Oncol, Phoenix, AZ, 1/1/2016
• Non-invasive immune monitoring following DC vaccination effectively delineates immune responses in glioblastoma
  Antonios J, Soto H, Everson R,…. Liau LM, Prins RM, 21st Annual Meeting of the Society for Neuro-Oncology, Neuro-Oncol, Phoenix, AZ, 1/1/2016
• Treatment with tumor lysate-pulsed autologous dendritic cells prolongs survival in patients with recurrent glioblastoma
  Bosch M, Prins RM, Liau LM, 106th American Association for Cancer Research (AACR) Annual Meeting, Cancer Research, Philadelphia, PA, 1/1/2015
• Targeting of novel GBM biomaker EMP2 results in decreased tumor growth and increased tumor necrosis
  Pelargos P, Qin Y, Voth B, Thill K, Chung L, Prins R, Liau LM, Ung N, Hojat S, Yong W, Gordon L, Wadehra M, Yang I, 20th Society for Neuro-Oncology Annual Meeting, Neuro-Oncol, San Antonio, TX, 1/1/2015
• Implicaiton of CpG island and SPINT2 hypermethylation in both IDH1 wild-type and mutant adult diffuse gliomas
  Liu F, Chowdhury R, Li T, Li S, Nguyen H, Wei B, Chou AP, Reiss JK, Mody RR, Liau LM, Nghiemphu PL, Yong WH, Cloughesy TF, Lai A, 20th Society for Neuro-Oncology Annual Meeting, Neuro-Oncol, San Antonio, TX, 1/1/2015
• Phase I dose-escalation study to test the safety of intratumoral adoptive immune therapy with alloCTL in recurrent glioma patients
  Hickey M, Soto H, Treger J, Erickson K, Malone C, Ha E, Young E, Prins RM, Liau LM, Kruse C, Society for Neuro-Oncology Annual Meeting, Neuro-Oncol, San Antonio, TX, 1/1/2015
• Next generation T-cell receptor sequencing can identify, quantify, and track tumor-specific T-cell populations before and after dendritic cell vaccination in glioblast...
  Sedighim S, Hsu M, Antonios J, Emerson R, Yusko E, Sanders C, Davidson T, Liau LM, Prins RM, Society for Neuro-Oncology Annual Meeting, Neuro-Oncol, San Antonio, TX, 1/1/2015
• Retroviral replicating vector-mediated delivery of an immunodominant neo-antigen epitope target for viro-immunotherapy in experimental glioma
  Kato Y, Scharnweber R, Inagaki A, Kamijima S, Hickey M, Lisiero D, Hermann K, Soto H, Antonios J, Sedighim S, Okada H, Liau LM, Klatzmann D, Prins RM, Kasahara N, 20th Society for Neuro-Oncology Annual Meeting, Neuro-Oncol, San Antonio, TX, 1/1/2015
• Large-scale UCLA glioma tissue microarray identifies EMP2 as a novel biomarker for GBM that correlates with overall prognosis
  Pelargos P, Qin Y, Voth B, Thill K, Chung L, Prins R, Liau LM, Ung N, Hojat S, Yong W, Gordon L, Wadehra M, Yang I, 20th Society for Neuro-Oncology Annual Meeting, Neuro-Oncol, San Antonio, TX, 1/1/2015
• High spatiotemporal dynamic susceptibility contrast (DSC) perfusion MRI using multi-band echoplanar imaging (MB-EPI)
  Ellingson B, Leu K, Pope W, Lai A, Ngheimphu PL, Liau LM, Cloughesy TF, 20th Society for Neuro-Oncology Annual Meeting, Neuro-Oncol, San Antonio, TX, 1/1/2015
• Improved leakage correction for dynamic susceptibility contrast (DSC) perfusion MRI estimates of relative cerebral blood volume (rCBV) in high-grade gliomas by account...
  Leu K, Boxerman J, Cloughesy TF, Lai A, Nghiemphu PL, Liau LM, Pope W, Ellingson B, 20th Society for Neuro-Oncology Annual Meeting, Neuro-Oncol, San Antonio, TX, 1/1/2015
• Therapeutic anti-glioma immunity is dependent on vaccination-induced T-cell responses and inhibition of iAPC function in the tumor microenvironment
  Antonios J, Soto H, Orpilla J, Shin N, Everson R, Liau LM, Prins RM, 20th Society for Neuro-Oncology Annual Meeting, Neuro-Oncol, San Antonio, TX, 1/1/2015
• Adjuvant inhibition of iAPC function in the tumor microenvironment promotes therapeutic immunity in the setting of vaccination-induced T-cell anti-tumor response
  Antonios J, Soto H, Orpilla J, Shin N, Everson R, Liau LM, Prins RM, 30th Annual Meeting of the Society for Immunotherapy of Cancer (SITC), Journal for Immunotherapy of Cancer, 1/1/2015
• Interim report from two ongoing ascending dose trials of retroviral replicating vector (Toca 511) in patients with recurrent high-grade glioma
  Jolly DJ, Ibanez C, Robbins JM,… Liau LM,… Pertschuk D, 17th Annual Meeting of the American Society of Gene and Cell Therapy, Washington, DC, 1/1/2014
• Glioblastoma presenting as lung metastasis: A unique case report and review of the literature
  Ng D, Wu A, Behbahanian Y, Liau LM, Vinters HV, 90th Annual Meeting of the American Association of Neuropathologists, 1/1/2014
• The IDH1 mutation in human glioblastoma and its effects on epigenetic modification and cell fate selection
  Garrett MC, Mottahedeh J, Sperry J,… Liau LM, Kornblum H, 105th American Association for Cancer Research (AACR) Annual Meeting, Cancer Research, San Diego, CA, 1/1/2014
• Intratumoral delivery of the retroviral replicating vector (RRV) TOCA511 in subjects with recurrent high-grade glioma: Interim report of Phase 1 study
  Aghi M, Vogelbaum MA, Kesari S, Chen CC, Liau LM, Piccioni D, Portnow J, Chang S, Robbins JM, Boyce T, Huang TT, Pertschuk D, Ostertag D, Cloughesy TF, 19th Society for Neuro-Oncology Annual Meeting, Neuro-Oncol, Miami, FL, 1/1/2014
• Join now to see all