LindseyRobertBadenMD

Infectious Disease • Boston, MA

Associate Professor of Medicine, Brigham and Women's Hospital

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Office
75 Francis Street
Brigham And Womens Hospital Div Of Infectious Disease
Boston, MA 02115
Phone+1 617-732-8881
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Summary

Dr. Lindsey Baden, MD is an infectious disease specialist in Boston, Massachusetts. He is currently licensed to practice medicine in Massachusetts, Rhode Island, and Maine. He is affiliated with Brigham and Women's Hospital and Dana-Farber Cancer Institute.

Education & Training

Beth Israel Deaconess Medical CenterFellowship, Infectious Disease, 1995 - 1999
Beth Israel Deaconess Medical CenterResidency, Internal Medicine, 1992 - 1995
Albert Einstein College of MedicineClass of 1992

Certifications & Licensure

ME State Medical License Current
MA State Medical License 1994 - 2025
RI State Medical License 2022 - 2024
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Infectious Disease

Clinical Trials

Comparison of Fluconazole vs Voriconazole to Treat Fungal Infections for Blood and Marrow Transplants (BMT CTN 0101) Start of enrollment: 2003 Nov 01
Completed
Phase 3
Safety of and Immune Response to an HIV Preventive Vaccine (HIV-1 Gag DNA Alone or With IL-15 DNA) Given With or Without 2 Different Booster Vaccinations in HIV Uninfected Adults
Completed
Phase 1
Safety of and Immune Response to an Adenoviral HIV-1 Vaccine in Healthy Adults Start of enrollment: 2008 Feb 01
Completed
Phase 1
Safety and Immune Response to a Recombinant Adenovirus HIV-1 Vaccine in Healthy Adults Start of enrollment: 2009 Feb 08
Completed
Phase 1
Efficacy of Post-operative Antibiotic Prophylaxis for Thoracic Surgery Requiring Tube Thoracostomy Start of enrollment: 2008 Mar 01
Completed
Not Applicable
Examining the Role of Genetics in Determining the Immune Response to an HIV Vaccine in HIV-Uninfected Adult Twins Start of enrollment: 2010 Jan 01
Completed
Phase 1
Evaluating the Safety and Immune Response of an Adenovirus-Based HIV Vaccine in HIV-Uninfected Adults Start of enrollment: 2010 Jul 01
Completed
Phase 1
Safety and Immunogenicity Study of Ad26-ENVA and Ad35-ENV HIV Vaccines in Healthy HIV-uninfected Adults Start of enrollment: 2010 Oct 01
Completed
Phase 1
Evaluating the Safety and Immune Response to Three Different Prime-Boost HIV Vaccine Regimens in Healthy, HIV-Uninfected Adults
Withdrawn
Phase 1
Multi-antigen CMV-MVA Triplex Vaccine in Reducing CMV Complications in Patients Previously Infected With CMV and Undergoing Donor Hematopoietic Cell Transplant Start of enrollment: 2015 Nov 05
Active, not recruiting
Phase 2
Evaluating the Safety and Immunogenicity of an HIV-1 gp41 MPER-656 Liposome Vaccine in Healthy, HIV-uninfected Adult Participants Start of enrollment: 2019 Aug 26
Completed
Phase 1
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Publications & Presentations

PubMed

COVID-19 vaccine efficacy in participants with weakened immune systems from four randomized-controlled trials.
Amy Sherman, Jessica Tuan, Valeria D Cantos, Oladunni Adeyiga, Scott Mahoney, Ana M Ortega-Villa, Amy Tillman, Jennifer Whitaker, Amanda S Woodward Davis, Brett Leav, ...> ;Clinical Infectious Diseases. 2024 Apr 10
A HIV-1 Gp41 Peptide-Liposome Vaccine Elicits Neutralizing Epitope-Targeted Antibody Responses in Healthy Individuals.
Nathan B Erdmann, Wilton B Williams, Stephen R Walsh, Nicole Grunenberg, Paul T Edlefsen, Paul A Goepfert, Derek W Cain, Kristen W Cohen, Janine Maenza, Kenneth H Maye...> ;Medrxiv. 2024 Mar 18
Author Correction: Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials.
Axfors, C., Schmitt, A., Janiaud, P., Van't Hooft, J., Abd-Elsalam, S., Abdo, E., Abella, B., Akram, J., Amaravadi, R., Angus, D., Arabi, Y., Azhar, S., Baden, L., Bak...> ;Nature Communications. 2024 Feb 5
Immune Control in RepeatedInfection in a Patient With B-Cell Deficiency.
Little, J., Oakley, M., Johnston, D., Majam, V., Liakos, A., Novack, L., Zheng, H., Meredith, S., Chou, C., Newton, B., Krause, P., Kumar, S., Thorner, A., Soiffer, R....> ;Open Forum Infectious Diseases. 2024 Jan 1
Infective Endocarditis Antibiotic Prophylaxis: Review of the Evidence and Guidelines.
Mia M Pries-Heje, Henning Bundgaard, Kasper K Iversen, Lindsey R Baden, Ann E Woolley> ;Current Cardiology Reports. 2023 Dec 1
2 citations
Opportunistic Infections in Patients Receiving Post-Transplantation Cyclophosphamide: Impact of Haploidentical versus Unrelated Donor Allograft.
Jessica S Little, Rémy Duléry, Roman M Shapiro, Muneerah M Aleissa, Susan E Prockop, John Koreth, Jerome Ritz, Joseph H Antin, Corey Cutler, Sarah Nikiforow, Rizwan Ro...> ;Transplantation and Cellular Therapy. 2024 Feb 1
Stochastic interventional approach to assessing immune correlates of protection: Application to the COVE messenger RNA-1273 vaccine trial.
Nima S Hejazi, Xiaoying Shen, Lindsay N Carpp, David Benkeser, Dean Follmann, Holly E Janes, Lindsey R Baden, Hana M El Sahly, Weiping Deng, Honghong Zhou, Brett Leav,...> ;International Journal of Infectious Diseases. 2023 Dec 1
1 citations
Immunogenicity of quadrivalent meningococcal conjugate vaccine in frequent platelet donors.
Michaël Desjardins, Phoebe Cunningham, Xhoi Mitre, Djenane Pierre, Christina Montesano, Tenaizus Woods, Karina Oganezova, Jonathan H Krauss, Salena S Von, John A Kupel...> ;Blood. 2023 Jul 13
1 citations
SARS-CoV-2 Vaccine-Induced Immune Responses Among Hematopoietic Stem Cell Transplant Recipients.
Afoke Kokogho, Trevor A Crowell, Muneerah Aleissa, Ana-Mihaela Lupan, Sonya Davey, Jun Bai Park Chang, Lindsey R Baden, Stephen R Walsh, Amy C Sherman> ;Open Forum Infectious Diseases. 2023 Jul 1
6 citations
Safety and Immunogenicity of Ad26-Vectored HIV Vaccine With Mosaic Immunogens and a Novel Mosaic Envelope Protein in HIV-Uninfected Adults: A Phase 1/2a Study.
Stieh, D., Barouch, D., Comeaux, C., Sarnecki, M., Stephenson, K., Walsh, S., Sawant, S., Heptinstall, J., Tomaras, G., Kublin, J., McElrath, M., Cohen, K., De Rosa, S...> ;The Journal of Infectious Diseases. 2023 Apr 18
Diagnostic TR-FRET assays for detection of antibodies in patient samples.
Hong Yue, Radosław P Nowak, Daan Overwijn, N Connor Payne, Stephanie Fischinger, Caroline Atyeo, Evan C Lam, Kerri St Denis, Lauren K Brais, Yoshinobu Konishi, Romanos...> ;Cell Reports Methods. 2023 Mar 27
7 citations
Severe Acute Respiratory Syndrome Coronavirus 2 Vaccine Immunogenicity among Chimeric Antigen Receptor T Cell Therapy Recipients.
Muneerah M Aleissa, Jessica S Little, Sonya Davey, Anna Saucier, Guohai Zhou, Isabel H Gonzalez-Bocco, Jennifer L Crombie, Andrew Looka, Lindsey R Baden, Nicolas C Iss...> ;Transplantation and Cellular Therapy. 2023 Jun 1
Lessons learned: A look back at the performance of nine COVID-19 serologic assays and their proposed utility.
Nicole V Tolan, Mia S DeSimone, Maria D Fernandes, Joshua E Lewis, Daimon P Simmons, Peter H Schur, Manfred Brigl, Milenko J Tanasijevic, Michaël Desjardins, Amy C She...> ;Clinical Biochemistry. 2023 Jul 1
4 citations
Trivalent mosaic or consensus HIV immunogens prime humoral and broader cellular immune responses in adults.
Kristen W Cohen, Andrew Fiore-Gartland, Stephen R Walsh, Karina Yusim, Nicole Frahm, Marnie L Elizaga, Janine Maenza, Hyman Scott, Kenneth H Mayer, Paul A Goepfert, Sr...> ;The Journal of Clinical Investigation. 2023 Feb 15
21 citations
Guidance on the Use of Convalescent Plasma to Treat Immunocompromised Patients With Coronavirus Disease 2019.
Evan M Bloch, Daniele Focosi, Shmuel Shoham, Jonathon Senefeld, Aaron A R Tobian, Lindsey R Baden, Pierre Tiberghien, David J Sullivan, Claudia Cohn, Veronica Dioverti...> ;Clinical Infectious Diseases. 2023 Jun 8
4 citations
Impact of Donor and Recipient SARS-CoV-2 Vaccination or Infection on Immunity after Hematopoietic Cell Transplantation.
Amy C Sherman, Chi-An Cheng, Zoe Swank, Guohai Zhou, Xiaofang Li, Nicolas C Issa, David R Walt, Lindsey R Baden, Robert J Soiffer> ;Transplantation and Cellular Therapy. 2023 May 1
8 citations
Rapid Development of an Integrated Network Infrastructure to Conduct Phase 3 COVID-19 Vaccine Trials.
Alfredo J Mena Lora, Jessica E Long, Yunda Huang, Lindsey R Baden, Hana M El Sahly, Dean Follmann, Paul Goepfert, Glenda Gray, Beatriz Grinsztejn, Karen Kotloff, Nadin...> ;JAMA Network Open. 2023 Jan 3
1 citations
Unsupervised outlier detection applied to SARS-CoV-2 nucleotide sequences can identify sequences of common variants and other variants of interest.
Georg Hahn, Sanghun Lee, Dmitry Prokopenko, Jonathan Abraham, Tanya Novak, Julian Hecker, Michael Cho, Surender Khurana, Lindsey R Baden, Adrienne G Randolph, Scott T ...> ;BMC Bioinformatics. 2022 Dec 19
Hidden in plain sight: urinary Cryptococcus neoformans missed by routine diagnostics in a patient with acute leukemia.
Zoe F Weiss, David W Basta, Stephanie Kent, Alexis Liakos, Lindsey Baden, Manfred Brigl, Sanjat Kanjilal, Connie Cañete-Gibas, Nathan P Wiederhold, Sankha S Basu, Jame...> ;Annals of Clinical Microbiology and Antimicrobials. 2022 Nov 12
5 citations
Humoral Immunogenicity of the mRNA-1273 Vaccine in the Phase 3 Coronavirus Efficacy (COVE) Trial.
Paris, R. M., Hana M El Sahly, Lindsey R Baden, Brandon Essink, David Montefiori, Adrian McDermont, Richard Rupp, Michael Lewis, Shobha Swaminathan, Carl Griffin, Vero...> ;The Journal of Infectious Diseases. 2022 Nov 11
6 citations
Bebtelovimab for High-Risk Outpatients With Early COVID-19 in a Large US Health System.
Scott Dryden-Peterson, Andy Kim, Mary-Ruth Joyce, Jennifer A Johnson, Arthur Y Kim, Lindsey R Baden, Ann E Woolley> ;Open Forum Infectious Diseases. 2022 Nov 1
The Cost-effectiveness of Transplanting Hearts From Hepatitis C-infected Donors Into Uninfected Recipients.
Ann E Woolley, Aditya R Gandhi, Michelle L Jones, Jane J Kim, Hari R Mallidi, Michael M Givertz, Lindsey R Baden, Mandeep R Mehra, And Anne M Neilan> ;Transplantation. 2023 Apr 1
11 citations
Vasculopathy and Increased Vascular Congestion in Fatal COVID-19 and Acute Respiratory Distress Syndrome.
Julian A Villalba, Caroline F Hilburn, Michelle A Garlin, Grant A Elliott, Yijia Li, Keiko Kunitoki, Sergio Poli, George A Alba, Emilio Madrigal, Manuel Taso, Melissa ...> ;American Journal of Respiratory and Critical Care Medicine. 2022 Oct 1
3 citations
Associations of Immunogenicity and Reactogenicity After Severe Acute Respiratory Syndrome Coronavirus 2 mRNA-1273 Vaccine in the COVE and TeenCOVE Trials.
Uma Siangphoe, Lindsey R Baden, Hana M El Sahly, Brandon Essink, Kashif Ali, Gary Berman, Joanne E Tomassini, Weiping Deng, Rolando Pajon, Roderick McPhee, Avika Dixit...> ;Clinical Infectious Diseases. 2023 Jan 13
374 citations
Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID-19.
O'Horo, J. C., Adarsh Bhimraj, Rebecca L Morgan, Amy Hirsch Shumaker, Lindsey Baden, Vincent Chi Chung Cheng, Kathryn M Edwards, Jason C Gallagher, Rajesh T Gandhi, Wi...> ;Clinical Infectious Diseases. 2022 Sep 5
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Press Mentions

I’m Worried About Going to Hospitals Without a MaskMay 10th, 2023
All Thumbs up from FDA Panel for Bacterial Pneumonia TherapyApril 18th, 2023
Advisors to the US Food and Drug Administration (FDA) Recommend Full Approval of Pfizer’s Covid Drug PaxlovidMarch 17th, 2023
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Hospital Affiliations

Brigham and Women's HospitalBoston, Massachusetts
Dana-Farber Cancer InstituteBoston, Massachusetts