LinglingXianMD

PubMed

• Metastatic Ovarian Serous Adenocarcinoma Clinically Presenting as Inflammatory Breast Cancer.
  Lingling Xian, Rachel Hunter, Emily Smith, Rasha Mohammed, Carlina Madelaire, Guillermo A Herrera, Rodney E Shackelford> ;Case Reports in Oncological Medicine. 2024 Jan 1
• 6 citations
  HMGA1 induces FGF19 to drive pancreatic carcinogenesis and stroma formation.
  Lionel Chia, Bowen Wang, Jung-Hyun Kim, Li Z Luo, Shuai Shuai, Iliana Herrera, Sophia Y Chen, Liping Li, Lingling Xian, Tait Huso, Mohammad Heydarian, Karen Reddy, Woo...> ;The Journal of Clinical Investigation. 2023 Mar 15
• 1 citations
  Adipokine C1q/Tumor Necrosis Factor- Related Protein 3 (CTRP3) Attenuates Intestinal Inflammation Via Sirtuin 1/NF-κB Signaling.
  Huimin Yu, Zixin Zhang, Gangping Li, Yan Feng, Lingling Xian, Fatemeh Bakhsh, Dongqing Xu, Cheng Xu, Tyrus Vong, Bin Wu, Florin M Selaru, Fengyi Wan, Mark Donowitz, G ...> ;Cellular and Molecular Gastroenterology and Hepatology. 2023 Jan 1
• 12 citations
  HMGA1 chromatin regulators induce transcriptional networks involved in GATA2 and proliferation during MPN progression.
  Liping Li, Jung-Hyun Kim, Wenyan Lu, Donna M Williams, Joseph Kim, Leslie Cope, Raajit K Rampal, Richard P Koche, Lingling Xian, Li Z Luo, Marija Vasiljevic, Daniel R ...> ;Blood. 2022 May 5
• 13 citations
  High mobility group A1 (HMGA1) protein and gene expression correlate with ER-negativity and poor outcomes in breast cancer
  Mikhail Gorbounov, Neil M. Carleton, Rebecca J Asch-Kendrick, Lingling Xian, Lisa M. Rooper, Lionel Chia, Ashley Cimino-Mathews, Leslie Cope, Alan K. Meeker, Vered Ste...> ;Breast Cancer Research and Treatment. 2020 Jan 1
• 8 citations
  Genetic Engineering of Primary Mouse Intestinal Organoids Using Magnetic Nanoparticle Transduction Viral Vectors for Frozen Sectioning.
  Lingling Xian, Lionel Chia, Dan Georgess, Li Luo, Shuai Shuai, Andrew J. Ewald, Linda M.S. Resar> ;Journal of Visualized Experiments. 2019 May 10
• 36 citations
  Lessons from the Crypt: HMGA1-Amping up Wnt for Stem Cells and Tumor Progression.
  Linda M.S. Resar, Lionel Chia, Lingling Xian> ;Cancer Research. 2018 Apr 15
• 33 citations
  IGF-I induced phosphorylation of PTH receptor enhances osteoblast to osteocyte transition
  Tao Qiu, Janet L. Crane, Liang Xie, Lingling Xian, Hui Xie, Xu Cao> ;Bone Research. 2018 Feb 26
• 55 citations
  HMGA1 amplifies Wnt signalling and expands the intestinal stem cell compartment and Paneth cell niche.
  Lingling Xian, Dan Georgess, Tait Huso, Leslie Cope, Amy Belton, Yu Ting Chang, Wenyong Kuang, Qihua Gu, Xiaoyan Zhang, Stefania Senger, Alessio Fasano, David L. Huso,...> ;Nature Communications. 2017 Apr 28
• 1 citations
  Hmga1 deficiency: "SAC-King" the SAC genes to incite chromosomal instability.
  Lingling Xian, Karen L. Reddy, Linda M.S. Resar> ;Cell Cycle. 2017 Jan 2
• 24 citations
  The High Mobility Group A1 (HMGA1) gene is highly overexpressed in human uterine serous carcinomas and carcinosarcomas and drives Matrix Metalloproteinase-2 (MMP-2) in...
  Joelle Hillion, Sujayita Roy, Mohammad Heydarian, Leslie Cope, Lingling Xian, Michael Koo, Li Z. Luo, Kathleen Kellyn, Brigitte M. Ronnett, Tait Huso, Deborah K. Armst...> ;Gynecologic Oncology. 2016 Jun 1
• 14 citations
  STAT3 inhibitor has potent antitumor activity in B-lineage acute lymphoblastic leukemia cells overexpressing the high mobility group A1 (HMGA1)–STAT3 pathway
  Amy Belton, Lingling Xian, Michael Koo, Li Z. Luo, James Turkson, Brent D. G. Page, Patrick T. Gunning, Guosheng Liu, David L. Huso, Linda M.S. Resar, Tait Huso> ;Leukemia & Lymphoma. 2016 Mar 8
• 52 citations
  Role of TGF-β Signaling in Coupling Bone Remodeling
  Janet L. Crane, Lingling Xian, Xu Cao> ;Methods in Molecular Biology. 2016 Jan 1
• 1 citations
  IBRUTinib: BRUTe force against bortezomib-resistant myeloma cells
  Lingling Xian, Carol Ann Huff, Linda M.S. Resar> ;Cell Cycle. 2015 Mar 18
• 539 citations
  PDGF-BB secreted by preosteoclasts induces angiogenesis during coupling with osteogenesis
  Hui Xie, Zhuang Cui, Long Wang, Zhuying Xia, Yin Hu, Lingling Xian, Changjun Li, Liang Xie, Janet L. Crane, Mei Wan, Gehua Zhen, Qin Bian, Bin Yu, Weizhong Chang, Tao ...> ;Nature Medicine. 2014 Nov 1
• 50 citations
  Functional Effects of TGF-β1 on Mesenchymal Stem Cell Mobilization in Cockroach Allergen–Induced Asthma
  Peisong Gao, Yufeng Zhou, Lingling Xian, Changjun Li, Ting Xu, Beverly Plunkett, Shau Ku Huang, Mei Wan, Xu Cao> ;Journal of Immunology. 2014 May 15
• 50 citations
  IGF-1 Signaling is Essential for Differentiation of Mesenchymal Stem Cells for Peak Bone Mass.
  Janet L. Crane, Luo Zhao, Joseph S. Frye, Lingling Xian, Tao Qiu, Xu Cao> ;Bone Research. 2013 Jun 28
• 415 citations
  Matrix IGF-1 maintains bone mass by activation of mTOR in mesenchymal stem cells
  Lingling Xian, Xiangwei Wu, Lijuan Pang, Michael Lou, Clifford J. Rosen, Tao Qiu, Janet L. Crane, Frank J. Frassica, Liming Zhang, Juan Pablo Rodríguez, Xiaofeng Jia, ...> ;Nature Medicine. 2012 Jul 1
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