LisaGuay-WoodfordMD
Pediatric Nephrology • Philadelphia, PACongenital Urologic and Renal Disorders
Professor of Pediatrics, University of Pennsylvania
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Office
9312 Roberts Center for Pediatric Research
734 Schuylkill Avenue
Philadelphia, PA 19146Phone+1 267-425-0315- Is this information wrong?
Summary
- My work as an academic pediatric nephrologist focuses on identifying clinical and genetic factors involved in the pathogenesis of inherited renal disorders, most notably autosomal recessive polycystic kidney disease (ARPKD). My laboratory participated in the identification of the human ARPKD gene as part of an international consortium and our group was the first to identify a candidate modifier gene for ARPKD. I have directed the NIDDK-funded Hepato-Renal Fibrocystic Disease Research and Translational Core Center, initially established when she was at the University of Alabama at Birmingham (UAB), and she continues to serve as co-Director of the UAB Childhood Cystic Kidney Disease Core Center. My research program has been funded by the NIH, the Burroughs Wellcome Fund Clinical Scientist Award in Translational Research, and the Polycystic Kidney Disease Foundation. In 2009, I was awarded the Lillian Jean Kaplan International Prize for Advancement in the Understanding of Polycystic Kidney Disease, given by the PKD Foundation and the International Society of Nephrology.
I recently assumed the role of Senior Advisor for Clinical and Translational Research Initiatives and Director of the Inherited Kidney Diseases Program at the Children’s Hospital of Philadelphia (CHOP) where I hold an endowed chair as a Presidential Professor in the Department of Pediatrics at the Perelman School of Medicine at the University of Pennsylvania.
Education & Training
Columbia University Vagelos College of Physicians and SurgeonsNo degree, Linkage Analysis Course, 1993
Boston Children's HospitalFellowship, 1987 - 1989- The Jackson LaboratoryNo degree, Medical and Mammalian Genetics, 1989
- Boston Children's HospitalResidency, 1983 - 1986
Harvard Medical SchoolClass of 1983- College of the Holy CrossB.A., Summa cum Laude, 1975 - 1979
Certifications & Licensure
PA State Medical License 2023 - 2024
DC State Medical License 2012 - 2024
AL State Medical License Active through 2012- American Board of Pediatrics Pediatrics
Publications & Presentations
PubMed
- Estimating risk of rapid disease progression in pediatric patients with autosomal dominant polycystic kidney disease: a randomized trial of tolvaptan.Djalila Mekahli, Lisa M Guay-Woodford, Melissa A Cadnapaphornchai, Stuart L Goldstein, Ann Dandurand, Huan Jiang, Pravin Jadhav, Laurie Debuque> ;Pediatric Nephrology. 2024 May 1
- 1 citationsPkhd1mice have altered renal Pkhd1 mRNA processing and hormonally sensitive liver disease.Chaozhe Yang, Naoe Harafuji, Ljubica Caldovic, Weiying Yu, Ravindra Boddu, Surajit Bhattacharya, Hayk Barseghyan, Heather Gordish-Dressman, Oded Foreman, Zsuzsa Bebok,...> ;Journal of Molecular Medicine. 2023 Sep 1
- 1 citationsDifferential regulation of MYC expression byin human and mouse kidneys: phenotypic implications for recessive polycystic kidney disease.Harafuji, N., Yang, C., Wu, M., Thiruvengadam, G., Gordish-Dressman, H., Thompson, R., Bell, P., Dafinger, C., Liebau, M., Bebok, Z., Caldovic, L., Rosenberg, A., Guay...> ;Frontiers in Cell and Developmental Biology. 2023 Jan 1
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Hospital Affiliations
Children's Hospital of PhiladelphiaPhiladelphia, Pennsylvania
Children's National HospitalWashington, District of Columbia
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