LloydScottMillerMD

PubMed

• 2 citations
  An oral caspase inhibitor as monotherapy or with antibiotics eradicates MRSA skin infections in mice.
  Emily Cahill, Olusola O Oladipo, Dustin Dikeman, Denion Prifti, Steven J Mento, Lloyd S Miller, Martin P Alphonse> ;Drug Development Research. 2023 Dec 1
• 2 citations
  Neutrophil-intrinsic TNF receptor signaling orchestrates host defense against.
  Christine Youn, Cristina Pontaza, Yu Wang, Dustin A Dikeman, Daniel P Joyce, Martin P Alphonse, Meng-Jen Wu, Sabrina J Nolan, Mohamed A Anany, Michael Ahmadi, Jeremy Y...> ;Science Advances. 2023 Jun 16
• 3 citations
  Ets1 and IL17RA cooperate to regulate autoimmune responses and skin immunity to.
  Michael Battaglia, Wei Luo, Richard Jin, Alifa Stith, Matt Lindemann, Lloyd S Miller, Satrajit Sinha, Elizabeth Wohlfert, Lee Ann Garrett-Sinha, Sunshine, A., Alex C S...> ;Frontiers in Immunology. 2023 Jan 1
• Crisaborole efficacy in murine models of skin inflammation and Staphylococcus aureus infection.
  Christine Youn, Dustin A Dikeman, Evelyn Chang, Haiyun Liu, Sabrina J Nolan, Martin P Alphonse, Daniel P Joyce, Qi Liu, James Meixiong, Xinzhong Dong, Lloyd S Miller, ...> ;Experimental Dermatology. 2023 Apr 1
• 13 citations
  Basophil-derived IL-4 promotes cutaneous Staphylococcus aureus infection
  Juan Manuel Leyva-Castillo, Mrinmoy Das, Jennifer Kane, Maria Strakosha, Sonal Singh, Daniel Sen Hoi Wong, Alexander R. Horswill, Hajime Karasuyama, Frank Brombacher, ...> ;JCI Insight. 2021 Nov 8
• 5 citations
  Neutrophil extracellular traps impair regeneration
  Eric M. Wier, Mayumi Asada, Gaofeng Wang, Martin P. Alphonse, Ang Li, Chase Hintelmann, Evan Sweren, Christine Youn, Brittany Pielstick, Roger V. Ortines, Chenyi Lyu, ...> ;Journal of Cellular and Molecular Medicine. 2021 Oct 8
• 1 citations
  Predilection for developing a hematogenous orthopaedic implant-associated infection in older versus younger mice
  John M. Thompson, Alyssa G. Ashbaugh, Yu Wang, Robert J. Miller, Julie E. Pickett, Daniel L.J. Thorek, Robert S. Sterling, Lloyd S. Miller> ;Journal of Orthopaedic Surgery and Research. 2021 Sep 14
• 1 citations
  Letter to the editor concerning the article: "Comparative safety and benefit-risk profile of biologics and oral treatments for moderate-to-severe plaque psoriasis: A n...
  Dan Pettitt, Michael Plotnick, Lloyd S. Miller, Jesse A. Berlin> ;Journal of the American Academy of Dermatology. 2021 Jul 23
• 16 citations
  Pan-caspase inhibition as a potential host-directed immunotherapy against MRSA and other bacterial skin infections.
  Ravipati, A., Martin P. Alphonse, Jessica H. Rubens, Roger V. Ortines, N.A. Orlando, Aman M. Patel, Dustin Dikeman, Yu Wang, Ivan Vuong, Daniel P. Joyce, Jeffrey Zhang...> ;Science Translational Medicine. 2021 Jul 7
• 23 citations
  Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection.
  Adela S. Oliva Chávez, Xiaowei Wang, Liron Marnin, Nathan K. Archer, Holly L. Hammond, Erin E.Mc Clure Carroll, Dana K. Shaw, Brenden G. Tully, Amanda D. Buskirk, Shel...> ;Nature Communications. 2021 Jun 17
• 57 citations
  Bacteria induce skin regeneration via IL-1β signaling
  Gaofeng Wang, Evan Sweren, Haiyun Liu, Eric M. Wier, Martin P. Alphonse, Ruosi Chen, Nasif Islam, Ang Li, Y. Xue, Junjie Chen, Seungman Park, Yun Chen, Sam Lee, Yu Wan...> ;Cell Host & Microbe. 2021 May 12
• 13 citations
  Comparative intravital imaging of human and rodent malaria sporozoites reveals the skin is not a species-specific barrier
  Christine S. Hopp, Sachie Kanatani, Nathan K. Archer, Robert J. Miller, Haiyun Liu, Kevin Chiou, Lloyd S. Miller, Photini Sinnis> ;EMBO Molecular Medicine. 2021 Apr 9
• 5 citations
  CCR2 contributes to host defense against Staphylococcus aureus orthopedic implant‐associated infections in mice
  Yu Wang, Dustin Dikeman, Jeffrey Zhang, Nicole E. Ackerman, Sophie E. Kim, Martin P. Alphonse, Roger V. Ortines, Haiyun Liu, Daniel P. Joyce, Carly A. Dillen, John M. ...> ;Journal of Orthopaedic Research. 2021 Mar 13
• 34 citations
  Epicutaneous Staphylococcus aureus induces IL-36 to enhance IgE production and ensuing allergic disease.
  Ravipati, A., Garrett J. Patrick, Haiyun Liu, Martin P. Alphonse, Dustin Dikeman, Christine Youn, Jack C. Otterson, Yu Wang, Advaitaa Ravipati, Momina Mazhar, George D...> ;The Journal of Clinical Investigation. 2021 Mar 1
• 9 citations
  Transmission of Antimicrobial-Resistant Staphylococcus aureus Clonal Complex 9 between Pigs and Humans, United States.
  Pranay R. Randad, Jesper Larsen, Hülya Kaya, Nora Pisanic, Carly Ordak, Lance B. Price, Maliha Aziz, Maya Nadimpalli, Sarah M. Rhodes, Jill R. Stewart, Dave C. Love, D...> ;Emerging Infectious Diseases. 2021 Mar 1
• 9 citations
  Comparison of two fluorescent probes in preclinical non-invasive imaging and image-guided debridement surgery of Staphylococcal biofilm implant infections
  Howard Y. Park, Stephen D. Zoller, Vishal Hegde, William L. Sheppard, Zachary D. C. Burke, Gideon Blumstein, Christopher D. Hamad, Marina M. Sprague, John Hoang, Ryan ...> ;Scientific Reports. 2021 Jan 15
• 15 citations
  Pathogenic and therapeutic role for NRF2 signaling in ultraviolet light–induced skin pigmentation
  Michelle L. Kerns, Robert J. Miller, Momina Mazhar, Angel S. Byrd, Nathan K. Archer, Bret L. Pinkser, Lance Lew, Carly A. Dillen, Ruizhi Wang, Lloyd S. Miller, Anna L....> ;JCI Insight. 2020 Oct 15
• 4 citations
  Lessons learned from the development of a hidradenitis suppurativa xenograft mouse model.
  Qaren Q. Quartey, Robert J. Miller, Bret L. Pinsker, Uchechukwu J. Okoh, William D. Shipman, Beth A. George, Chibuikem Nwizu, Leandra A. Barnes, Michelle L. Kerns, Jul...> ;Clinical and Experimental Dermatology. 2020 Mar 1
• 14 citations
  Rabbit model of Staphylococcus aureus implant-associated spinal infection
  Oren Gordon, Robert J. Miller, John M. Thompson, Alvaro A. Ordonez, Mariah H. Klunk, Dustin Dikeman, Daniel P. Joyce, Camilo A. Ruiz-Bedoya, Lloyd S. Miller, Sanjay K....> ;Disease Models & Mechanisms. 2020 Jan 1
• 9 citations
  Preclinical Optical Imaging to Study Pathogenesis, Novel Therapeutics and Diagnostics Against Orthopaedic Infection.
  John M. Thompson, Lloyd S. Miller> ;Journal of Orthopaedic Research. 2019 Nov 1
• 3 citations
  Psoriasiform drug eruption secondary to sorafenib: case series and review of the literature.
  Courtney J. Ensslin, Pei Han Kao, Ming Ying Wu, Yao Yu Chang, Tseng Tong Kuo, Chia-Hsun Hsieh, Sen Yung Hsieh, Chih Hsun Yang, Lloyd S. Miller> ;Cutis. 2019 Sep 1
• 9 citations
  Specimen Collection for Translational Studies in Hidradenitis Suppurativa.
  Angel S. Byrd, Yemisi Dina, Uchechukwu J. Okoh, Qaren Q. Quartey, Carmelo Carmona-Rivera, Dionna W. Williams, Michelle L. Kerns, Robert J. Miller, Lynn Petukhova, Hale...> ;Scientific Reports. 2019 Aug 21
• Theranostic biocomposite scaffold membrane.
  Roussakis, E.,Ortines, R. V.,Pinsker, B. L.,Mooers, C. T.,Evans, C. L.,Miller, L. S.,Calderón-Colón, X.> ;Biomaterials. 2019 May 18
• 8 citations
  A Mouse Model to Assess Innate Immune Response to Staphylococcus aureus Infection.
  Leif S. Anderson, Mack B. Reynolds, Kathryn R. Rivara, Lloyd S. Miller, Scott I. Simon> ;Journal of Visualized Experiments. 2019 Feb 28
• 17 citations
  In Vivo Bioluminescence Imaging in a Rabbit Model of Orthopaedic Implant-Associated Infection to Monitor Efficacy of an Antibiotic-Releasing Coating.
  Robert J. Miller, John M. Thompson, Jesse Zheng, Mark C. Marchitto, Nathan K. Archer, Bret L. Pinsker, Roger V. Ortines, Xuesong Jiang, Russell Martin, Isabelle D. Bro...> ;The Journal of Bone and Joint Surgery. American Volume. 2019 Feb 20
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Journal Articles

• Fibroblast Growth Factor 2 Dimer with Superagonist In Vitro Activity Improves Granulation Tissue Formation During Wound Healing  
  Decker, CG, Wang, Y, Paluck, SJ, Shen, L, Loo, JA, Levine, AJ, Miller, LS, Maynard, HD, Biomaterials, 1/1/2016
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  Barin, JG, Talor, MV, Schaub, JA, Diny, NL, Hou, X, Hoyer, M, Archer, NK, Gebremariam, ES, Davis, MF, Miller, LS, Rose, NR, Cihakova, D, American Journal of Pathology, 1/1/2016
• IL-22 derived from Gamma-Delta T cells restricts Staphylococcus aureus colonization on mechanically injured skin  
  Malhotra, N, Yoon, J, Leyva-Castillo, JM, Galand, C, Archer, N, Miller, LS, Geha, RS, Journal of Allergy and Clinical Immunology, 1/1/2016
• A novel in vivo mouse model of implant related spine infection  
  Dworsky E, Hegde, V, Loftin, A, Richman, S, Hu, Y, Lord, E, Francis, K, Miller, LS, Wang, J, Scaduto, A, Bernthal, NM, Journal of Orthopaedic Research, 1/1/2016
• Polymeric nanofiber coating with tunable combinatorial antibiotic delivery prevents biofilm-associated infection in vivo  
  Ashbaugh, AG, Jiang, X, Zheng, J, Tsai, AS, Kim, W-S, Thompson, JM, Miller, RJ, Shahbazian, JH, Wang, Y, Ordonez, AA, Chang, YS, Jain, SK, Jones, JC, Sterling, RS, Mao..., Proceedings of the National Academy of Sciences, 1/1/2016
• IL-17A and IL-17F are critical for antimicrobial peptide production and clearance of Staphylococcus aureus nasal colonization  
  Archer, N, Adappa, M, Palmer, J, Cohen, N, Harro, J, Lee, S, Miller, LS, Shirtliff, M, Infection and Immunity, 1/1/2016
• dsRNA Released by Tissue Damage Activates TLR3 to Drive Skin Regeneration  
  Nelson, AM, Reddy, SK, Ratliff, TS, Hossian, MZ, Katseff, AS, Zhu, AS, Chang, E, Resnik, SR, Page, C, Kim, D, Whittam, AJ, Miller, LS, Garza, LA, Cell Stem Cell, 1/1/2015
• Non-Redundant Roles of IL-17A and IL-22 in Murine Host Defense against Cutaneous and Hematogenous Infection Due to Methicillin-Resistant Staphylococcus aureus  
  Chan, LC, Chaili, S, Filler, SG, Barr, K, Wang, H, Kupferwasser, D, Edwards, JE, Xiong, YQ, Ibrahim, AS, Miller, LS, Schmidt, CS, Hennessey, JS, Yeaman, MR, Infection and Immunity, 1/1/2015
• Combination Prophylactic Therapy with Rifampin has Increased Efficacy Against an Experimental Staphylococcus epidermidis Subcutaneous Implant-Related Infection  
  Stavrakis, AI, Niska, JA, Shahbazian, JH, Loftin, AH, Ramos, RI, Billi, F, Francis, KP, Otto, M, Bernthal, NM, Uslan, DZ, Miller, LS., Antimicrobial Agents and Chemotherapy, 1/1/2014
• Combined in vivo optical and MuCT imaging to monitor infection, inflammation and bone anatomy in an orthopaedic implant infection in mice  
  Bernthal, NM, Taylor, BN, Meganck, JA, Wang, Y, Shahbazian, JH, Niska, JA, Francis, KP, Miller, LS, Journal of Visualized Experiments, 1/1/2014
• Broad-Spectrum Antimicrobial and Biofilm-Disrupting Hydrogels: Stereocomplex-Driven Supramolecular Assemblies  
  Li, Y, Fukushima, K, Coady, DJ, Engler, AC, Liu, S, Huang, Y, Cho, JS, Guo, Y, Miller, LS, Tan, JK, Ee, PL, Fan, W, Yang, YY, Hedrick, JL, Angewandte Chemie International Edition, 1/1/2013
• In vivo bioluminescence imaging to evaluate systemic and topical antibiotics against community-acquired methicillin-resistant Staphylococcus aureusinfected skin wounds...  
  Guo, Y, Ramos, RI, Cho, JS, Donegan, NP, Cheung, AL, Miller, LS, Antimicrobial Agents and Chemotherapy, 1/1/2013
• Vancomycin-Rifampin Combination Therapy Has Enhanced Efficacy against an Experimental Staphylococcus aureus Prosthetic Joint Infection  
  Niska, JA, Shahbazian, JH, Ramos, RI, Francis, KP, Miller, LS, Antimicrobial Agents and Chemotherapy, 1/1/2013
• Mouse model of chronic post-arthroplasty infection: noninvasive in vivo bioluminescence imaging to monitor bacterial burden for longterm study  
  Pribaz, JR, Bernthal, NM, Billi, F, Cho, JS, Ramos, RI, Francis, KP, Miller, LS, Journal of Orthopaedic Research, 1/1/2012
• Coordinate regulation of neutrophil homeostasis by liver X receptors in mice  
  Hong, C, Kidani, Y, A-Gonzalez, N, Phung, T, Ito, A, Rong, X, Ericson, K, Mikkola, H, Beaven, SW, Miller, LS, Shao, WH, Cohen, PL, Castrillo, A, Tontonoz, P, Bensinger..., Journal of Clinical Investigation, 1/1/2012
• Daptomycin and tigecycline have a broader effective dose range than vancomycin as prophylaxis against a surgical implant Staphylococcus aureus infection in mice  
  Niska, JA, Shahbazian, JH, Ramos, RI, Pribaz, JR, Billi, F, Francis, KP, Miller, LS, Antimicrobial Agents and Chemotherapy, 1/1/2012
• Cutting Edge: Nitrogen bisphosphonate-induced inflammation Is dependent upon mast cells and IL-1  
  Norton, JT, Hayashi, T, Crain, B, Cho, JS, Miller, LS, Corr, M, Carson, DA, Journal of Immunology, 1/1/2012
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  Niska, JA, Meganck, JA, Pribaz, JR, Shahbazian, JH, Lim, E, Zhang, N, Rice, BW, Ramos, RI, Bernthal, NM, Francis, KP, Miller, LS, Plos ONE, 1/1/2012
• Silver nanoparticle/poly(DL-lactic-co-glycolic acid)-coated stainless steel alloy: an antimicrobial and osteoinductive material for orthopedic device fabrication  
  Liu, Y, Zheng, Z, Zara, JN, Hsu, CY, Soffer, DE, Lee, KS, Siu, RK, Miller, LS, Zhang, X, Carpenter, D, Wang, C, Ting, K, Soo, C, Biomaterials, 1/1/2012
• LTB4 driven neutrophil recruitment to the skin is essential for allergic skin inflammation  
  Oyoshi, MK, He,R, Li, Y, Mondal, S, Yoon, J, Afshar, R, Chen, M, Lee, DM, Luo, HR, Luster, AD, Cho, JS, Miller, LS, Larson, Murphy, GF, Geha, RS, Immunity, 1/1/2012
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  Cho, JS, Guo, Y, Ramos, RI, Hebroni, F, Plaisier, SB, Xuan, C, Granick, JL, Matsushima, H, Takashima, A, Iwakura, Y, Cheung, AL, Cheng, G, Lee, DJ, Simon, SI, Miller, LS, PLOS Pathogens, 1/1/2012
• Host-pathogen interactions involving the skin and Staphylococcus aureus (Review Article)  
  Krishna, S, Miller, LS, Current Opinions in Microbiology, 1/1/2012
• The innate and adaptive immune response against Staphylococcus aureus skin infections (Review Article)  
  Krishna, S, Miller, LS, Seminars in Immunopathology, 1/1/2012
• Noninvasive in vivo imaging to evaluate immune responses and antimicrobial therapy against Staphylococcus aureus and USA300 MRSA skin infections  
  Cho, JS, Zussman, J, Donegan, NP, Ramos, RI, Garcia, NC, Uslan, DZ, Iwakura, Y, Simon, SI, Cheung, AL, Modlin, RL, Kim, J, Miller, LS, Journal of Investigative Dermatology, 1/1/2011
• Neutrophil survival and c-kit+ progenitor proliferation in Staphylococcus aureus infected skin wounds promote resolution  
  Kim, M-H, Granick, JL, Kwok, C, Walker, N, Borjesson, DL, Curry, FE, Miller, LS, Simon, SI, Blood, 1/1/2011
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Books/Book Chapters

• Fitzpatrick's Dermatology in General Medicine 
  Chapter: Innate and Adaptive Immunity in the Skin 
  Page 105 - 125Modlin, RL, Miller, LS, Bangert, C, Stingl, GMcGraw-HillEdition 8th,2012
• Clinical and Basic Immunodermatology 
  Chapter: Bacterial infections 
  Page 335 - 363Senavsky, C, Craft, N, Miller, LSEditors: Gaspari, AA, Tyring, SK.Springer, Guildford, United Kingdom2008

Lectures

• Recent Insights into Skin Immunity Against MRSA infection 
  Baltimore, MD - 1/1/2016
• Recent Insights into Immunity against Staphylococcus aureus Skin Infections 
  Multiple locations, 2014, 2015, 2016 - 1/1/2016
• Noninvasive multimodality in vivo imaging to study Staphylococcus aureus prosthetic joint infections, bacteremia and atopic dermatitis 
  Tarrytown, NY - 1/1/2016
• Development of a Composite Implant Coating with Tunable Combinatory Antibiotic Delivery to Prevent Prosthetic Joint Infection 
  Bethesda, MD - 1/1/2016
• An innate-like pathway protects against Staphylococcus aureus skin reinfection 
  Bethesda, MD - 1/1/2016
• Multimodality imaging to study the pathogenesis and novel therapeutics and diagnostics against an experimental prosthetic joint infection 
  Omaha, NE - 1/1/2016
• IL-1Beta and IL-17 in innate and adaptive skin immunity to Staphylococcus aureus 
  Sacramento, CA - 1/1/2016
• IL-1Beta and the inflammasome in immunity to Staphylococcus aureus skin infection 
  Davis, CA - 1/1/2016
• Host Defense Mechanisms for Skin Infections 
  Seoul, South Korea - 1/1/2016
• Common Bacterial Skin Infections 
  1/19/2015
• Pharmacologic agents against viral infections in Dermatology 
  1/18/2015
• Pharmacologic agents against fungal and parasitic infections in Dermatology 
  1/16/2015
• Pharmacologic agents against bacterial infections in Dermatology 
  1/7/2015
• IL-1 and IL-17 responses in immunity against Staphylococcus aureus skin infections 
  Multiple locations, 2012, 2013, 2015 - 1/1/2015
• Introduction to Translational Aspects of Staphylococcal Diseases 
  Tuscany, Italy - 1/1/2015
• In vivo bioluminescence, fluorescence, MuCT and photoacoustic imaging to noninvasively evaluate pathogenesis, therapeutics and diagnostics in an experimental orthopaed... 
  Baltimore, MD - 1/1/2015
• Novel bioengineered antimicrobial surgical implant coatings to prevent prosthetic joint infections 
  Johns Hopkins University School of Medicine Baltimore, MD - 1/1/2014
• Mechanisms of immune protection of multifunctional monoclonal antibodies against Staphylococcus aureus infections 
  Gaithersburg, MD - 1/1/2014
• Noninvasive Monitoring of Bacteria Burden, Inflammation and Efficacy of Antimicrobial Therapy in Infected Wounds in Mice Using Optical Imaging 
  Washington, DC - 1/1/2014
• Noninvasive in vivo optical and anatomical imaging in mice provides novel insights into the pathogenesis, treatment and diagnosis of S. aureus infections 
  Silver Spring, MD - 1/1/2014
• Optical and MuCT imaging to evaluate infection, inflammation, bone anatomy and diagnostic bacterial-specific probes in an in vivo orthopaedic implant infection in mice 
  Seoul, South Korea - 1/1/2014
• Mouse models of Staphylococcus aureus infections to study immune responses - What have we learned? 
  Johns Hopkins University School of Medicine Baltimore, MD - 1/1/2013
• Optical imaging for bacterial infections: Skin, joint and bone 
  Johns Hopkins University School of Medicine Baltimore, MD - 1/1/2013
• Mouse models of Staphylococcus aureus infections to study pathogenesis, immune responses and antimicrobial therapy 
  Johns Hopkins University School of Medicine Baltimore, MD - 1/1/2013
• Mechanisms that Promote Neutrophil Recruitment against Staphylococcus aureus Skin Infections 
  Washington, DC, 2013; University of Utah, Salt Lake City, UT, 2013; National Institute of Allergy an - 1/1/2013
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Other

• Nanofiber coating prevents infections of prosthetic joints 
  ScienceDaily
  1/1/2016
• Nanofiber Coating Eliminates Infections 
  Orthopedics This Week
  1/1/2016
• Nanofiber Coating Improve Joint Replacements in Lab Mice 
  ALN Magazine
  1/1/2016
• Shedding Light on Immunity in Johns Hopkins-MedImmune Collaboration 
  Johns Hopkins Technology Ventures
  1/27/2015
• An Electrospun Polymer Implant Coating as a Tunable Antimicrobial Release Delivery System to Prevent Prosthetic Joint Infections 
  Johns Hopkins Institute for Clinical and Translational Research
  1/21/2015
• Immunology Research Shows Great Promise in Treating Aggressive Skin Infections 
  Johns Hopkins Department of Dermatology Spring Newsletter
  1/18/2015
• In vivo optical imaging that's being used for the rapid and early diagnosis of bacterial colonization 
  American Medicine Today
  1/10/2015
• Picturing Infection: Whole-animal, light-based imaging of infected small mammals 
  The Scientist
  1/1/2015
• Unlocking the Mystery Behind MRSA 
  Johns Hopkins Health After 50 Newsletter
  1/1/2014
• Speeding up wound healing with debridement 
  Johns Hopkins Health After 50 Newsletter
  1/1/2013
• Bacteriology: Staph infections in the skin controlled by the immune molecule IL-17 
  ScienceDaily
  1/1/2010
• IL-1 can act as number one 
  Immunity
  1/1/2006
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