LoriJGoldsteinMD

Oncology • Philadelphia, PA

Breast Cancer, Hematologic Oncology

Professor of Medicine, Temple University

Join to view full profile

Dr. Goldstein is on Doximity

As a Doximity member you'll join over two million verified healthcare professionals in a private, secure network.

Connect with other colleagues in the same hospital or clinic
Search all U.S. specialist profiles and refer a patient
Read the latest clinical news and earn CME/CEU credits

See Dr. Goldstein's full profile

Already have an account?

Office
333 Cottman Ave
Fox Chase Cancer Center
Philadelphia, PA 19111
Phone+1 215-728-6900
Is this information wrong?

Education & Training

National Institutes of Health Clinical CenterFellowship, Hematology and Medical Oncology, 1986 - 1989
UPMC Medical EducationResidency, Internal Medicine, 1985 - 1986
UPMC Medical EducationResidency, Internal Medicine, 1982 - 1985
SUNY Upstate Medical UniversityClass of 1982
University of PennsylvaniaBA, Molecular Biology, Cum Laude; Brownlee Award, 1974 - 1978

Certifications & Licensure

PA State Medical License 1983 - 2024
MD State Medical License 1986 - 1992
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

Philadelphia Magazine Castle Connolly, 2004-2014
America's Top Doctors Castle Connolly, 2002-2014
America's Top Doctors for Cancer Castle Connolly, 2005-2013
Fellow (FASCO) American Society of Clinical Oncologists, 2011
Redbook Magazine: Top Breast Cancer Doctors Castle Connolly, 2001
Join now to see all

Clinical Trials

Combination Chemotherapy in Treating Women With Breast Cancer Start of enrollment: 1998 Aug 20
Completed
Phase 3
S0230 Goserelin in Preventing Ovarian Failure in Women Receiving Chemotherapy for Breast Cancer Start of enrollment: 2003 Oct 01
Completed
Phase 3
Combination of Oral WX-671 Plus Capecitabine vs. Capecitabine Monotherapy in First-line Her2-negative Metastatic Breast Cancer Start of enrollment: 2008 Jul 01
Completed
Phase 2
Identifying Genes That Predict Recurrence in Women With Breast Cancer Treated With Chemotherapy Start of enrollment: 2005 Oct 07
Completed
A Phase III Randomized Trial of Metformin vs Placebo in Early Stage Breast Cancer Start of enrollment: 2010 Aug 13
Completed
Phase 3
Tamoxifen Citrate, Letrozole, Anastrozole, or Exemestane With or Without Chemotherapy in Treating Patients With Invasive RxPONDER Breast Cancer Start of enrollment: 2011 Jan 15
Active, not recruiting
Phase 3
S1207 Hormone Therapy With or Without Everolimus in Treating Patients With Breast Cancer Start of enrollment: 2013 Sep 12
Active, not recruiting
Phase 3
Study of Fulvestrant +/- Everolimus in Post-Menopausal, Hormone-Receptor + Metastatic Breast Ca Resistant to AI Start of enrollment: 2013 May 31
Completed
Phase 2
Pilot Study to Evaluate Safety & Biological Effects of Orally Administered Reparixin in Early Breast Cancer Start of enrollment: 2013 Feb 01
Terminated
Phase 2
Heavy Metal Exposure in Predicting Peripheral Neuropathy in Patients With Stage I-III Breast Cancer Undergoing Chemotherapy Start of enrollment: 2011 Jan 03
Completed
Pilot Study to Evaluate Reparixin With Weekly Paclitaxel in Patients With HER 2 Negative Metastatic Breast Cancer (MBC) Start of enrollment: 2012 Feb 27
Completed
Phase 1
Clinical Trial of Atezolizumab With Paclitaxel, Trastuzumab, and Pertuzumab in Patients With Metastatic HER-2 Positive Breast Cancer Start of enrollment: 2017 Jun 13
Active, not recruiting
Phase 2
Join now to see all

Publications & Presentations

PubMed

4 citations
Computational pathology improves risk stratification of a multi-gene assay for early stage ER+ breast cancer.
Yuli Chen, Haojia Li, Andrew Janowczyk, Paula Toro, Germán Corredor, Jon Whitney, Cheng Lu, Can F Koyuncu, Mojgan Mokhtari, Christina Buzzy, Shridar Ganesan, Michael D...> ;NPJ Breast Cancer. 2023 May 17
1 citations
Psychosocial needs of older patients with metastatic breast cancer treated at community centers.
Khyati H Somayaji, Elizabeth Handorf, Caitlin R Meeker, Bianca Lewis, Kelly Filchner, Lori J Goldstein, Efrat Dotan> ;Journal of Geriatric Oncology. 2023 Mar 1
13 citations
Cisplatin with veliparib or placebo in metastatic triple-negative breast cancer and BRCA mutation-associated breast cancer (S1416): a randomised, double-blind, placebo...
Eve Rodler, Priyanka Sharma, William E Barlow, Julie R Gralow, Shannon L Puhalla, Carey K Anders, Lori Goldstein, Debu Tripathy, Ursa A Brown-Glaberman, Thu-Tam Huynh,...> ;The Lancet. Oncology. 2023 Feb 1
3 citations
Racial inequities in second-line treatment and overall survival among patients with metastatic breast cancer.
Kristen D Whitaker, Xiaoliang Wang, Mustafa Ascha, Timothy N Showalter, Heather G Lewin, Gregory S Calip, Lori J Goldstein> ;Breast Cancer Research and Treatment. 2022 Nov 1
2 citations
Reply to B. Ulaş Kahya et al and A. Soran et al.
Seema Ahsan Khan, Fengmin Zhao, Lori Goldstein, Joseph Sparano, George Sledge> ;Journal of Clinical Oncology. 2022 Nov 20
4 citations
Systemic Therapies Following Progression on First-line CDK4/6-inhibitor Treatment: Analysis of Real-world Data.
James M Martin, Elizabeth A Handorf, Alberto J Montero, Lori J Goldstein> ;The Oncologist. 2022 Jun 8
286 citations
Breast Cancer, Version 3.2022, NCCN Clinical Practice Guidelines in Oncology.
Elias, A., Savur Moran, M. S., William J Gradishar, Meena S Moran, Jame Abraham, Rebecca Aft, Doreen Agnese, Kimberly H Allison, Bethany Anderson, Harold J Burstein, H...> ;Journal of the National Comprehensive Cancer Network. 2022 Jun 1
64 citations
Early Local Therapy for the Primary Site in De Novo Stage IV Breast Cancer: Results of a Randomized Clinical Trial (EA2108).
Seema A Khan, Fengmin Zhao, Lori J Goldstein, David Cella, Mark Basik, Mehra Golshan, Thomas B Julian, Barbara A Pockaj, Christine A Lee, Wajeeha Razaq, Joseph A Spara...> ;Journal of Clinical Oncology. 2022 Mar 20
Prospective Comparison of Geriatric Assessment and Provider's Assessment of Older Adults With Metastatic Breast Cancer in the Community.
Rino S Seedor, Caitlin R Meeker, Bianca Lewis, Elizabeth A Handorf, Kelly A Filchner, Ramya Varadarajan, Jack Hensold, Aruna Padmanabhan, Benjamin Negin, Kenneth Blank...> ;The Oncologist. 2022 Mar 4
22 citations
Niraparib for Advanced Breast Cancer with Germline BRCA1 and BRCA2 Mutations: the EORTC 1307-BCG/BIG5-13/TESARO PR-30-50-10-C BRAVO Study
Nicholas C. Turner, Judith Balmaña, C. Poncet, Theodora Goulioti, Konstantinos Tryfonidis, Aafke H. Honkoop, Gabriele Zoppoli, Evangelia Razis, Oskar T. Johannsson, Ma...> ;Clinical Cancer Research. 2021 Oct 15
30 citations
A randomized, placebo-controlled phase 2 study of paclitaxel in combination with reparixin compared to paclitaxel alone as front-line therapy for metastatic triple-neg...
Lori J. Goldstein, Mauro Mansutti, Christelle Levy, Jenny C. Chang, Stephanie Henry, Isaura Fernandez-Perez, Jana Prausovà, Elżbieta Starosławska, Giuseppe Viale, Beth...> ;Breast Cancer Research and Treatment. 2021 Sep 3
24 citations
Collagen fiber orientation disorder from H&E images is prognostic for early stage breast cancer: clinical trial validation.
Haojia Li, Kaustav Bera, Paula Toro, Ping Fu Fu, Zelin Zhang, Cheng Lu, Michael Feldman, Shridar Ganesan, Lori J. Goldstein, Nancy E. Davidson, Akisha Glasgow, Aparna ...> ;NPJ Breast Cancer. 2021 Aug 6
150 citations
NCCN Guidelines® Insights: Breast Cancer, Version 4.2021.
William J Gradishar, Meena S Moran, Jame Abraham, Rebecca Aft, Doreen Agnese, Kimberly H Allison, Sarah L Blair, Harold J Burstein, Chau Dang, Anthony D Elias, Sharon ...> ;Journal of the National Comprehensive Cancer Network. 2021 May 1
2 citations
In Support of CDK4/6 Inhibitors-A Meta-analysis of Available Randomized Data.
James Michael Martin, Lori J. Goldstein> ;JAMA Network Open. 2020 Oct 1
3 citations
Efficacy of eribulin for metastatic breast cancer based on localization of specific secondary metastases: a post hoc analysis.
Joyce O'Shaughnessy, Javier Cortes, Chris Twelves, Lori J. Goldstein, Karenza Alexis, Ran Xie, Carlos Barrios, Takayuki Ueno> ;Scientific Reports. 2020 Jul 8
Benefits of Digital Breast Tomosynthesis Beyond Baseline Screening.
Catherine Tuite, Maggie L. DiNome, Lori J. Goldstein> ;JAMA Network Open. 2020 Jul 1
2 citations
Correction to: A window-of-opportunity trial of the CXCR1/2 inhibitor reparixin in operable HER-2-negative breast cancer.
Lori J. Goldstein, Raymond P. Perez, Denise A. Yardley, Linda K. Han, James M. Reuben, Hui Gao, Susan McCanna, Beth Butler, Pier Adelchi Ruffini, Yi Liu, Roberto R. Ro...> ;Breast Cancer Research. 2020 May 20
6 citations
Role of Capecitabine in Early Breast Cancer.
Asya N. Varshavsky-Yanovsky, Lori J. Goldstein> ;Journal of Clinical Oncology. 2020 Jan 20
52 citations
A window-of-opportunity trial of the CXCR1/2 inhibitor reparixin in operable HER-2-negative breast cancer.
Lori J. Goldstein, Raymond P. Perez, Denise A. Yardley, Linda K. Han, James M. Reuben, Hui Gao, Susan McCanna, Beth Butler, Pier Adelchi Ruffini, Yi Liu, Roberto R. Ro...> ;Breast Cancer Research. 2020 Jan 10
11 citations
Neratinib in Combination With Trastuzumab for the Treatment of Patients With Advanced HER2-positive Breast Cancer: A Phase I/II Study.
Kimberly L. Blackwell, Khalil Zaman, Shukui Qin, K. Tkaczuk, Mario Campone, Daniel Hunt, Richard Bryce, Lori J. Goldstein> ;Clinical Breast Cancer. 2019 Apr 1
55 citations
Final Analysis of the Prevention of Early Menopause Study (POEMS)/SWOG Intergroup S0230.
Halle C. F. Moore, Joseph M. Unger, Kelly-Anne Phillips, Frances M. Boyle, Erika Hitre, Anna Moseley, David Porter, Prudence A. Francis, Lori J. Goldstein, Henry L. Go...> ;Journal of the National Cancer Institute. 2019 Feb 1
171 citations
Breast cancer, version 3.2018 featured updates to the NCCN guidelines
Matthew P. Goetz, William J. Gradishar, Benjamin O. Anderson, Jame Abraham, Rebecca Aft, Kimberly H. Allison, Sarah L. Blair, Harold J. Burstein, Chau T. Dang, Anthony...> ;Journal of the National Comprehensive Cancer Network. 2019 Feb 1
22 citations
Treatment delays from transfers of care and their impact on breast cancer quality measures
Richard J. Bleicher, Cecilia Chang, Chihsiung E. Wang, Lori J. Goldstein, Cary S. Kaufmann, Meena S. Moran, Karen A. Pollitt, Nicholas R. Suss, David P. Winchester, Lo...> ;Breast Cancer Research and Treatment. 2019 Feb 1
21 citations
Profile of abemaciclib and its potential in the treatment of breast cancer.
James Michael Martin, Lori J. Goldstein> ;Oncotargets and Therapy. 2018 Aug 29
46 citations
Double-blind phase III trial of adjuvant chemotherapy withand without bevacizumab in patients with lymph node-positiveand high-risk lymph node-negative breast cancer (...
Kathy D. Miller, Anne O'Neill, William J. Gradishar, Timothy J. Hobday, Lori J. Goldstein, Ingrid A. Mayer, Stuart Hunegs Bloom, Adam Brufsky, Amye J. Tevaarwerk, Jose...> ;Journal of Clinical Oncology. 2018 Jul 24
Join now to see all

Journal Articles

In Support of CDK4/6 Inhibitors—A Meta-Analysis of Available Randomized Data
Lori Goldstein, MD, JAMA Network Open

Press Mentions

1 NCCN Guidelines for Patients® Inflammatory Breast Cancer, 2023March 23rd, 2023
Gene-Expression Profiling Raises Costs for Cancer Care Without Improving Outcomes for Low-Risk Breast Cancer Patients, According to ResearchersJanuary 22nd, 2019

Grant Support

Eastern Cooperative Oncology GroupNational Cancer Institute2003–2011
Development Of Breast Cancer Research Program At FcccNational Cancer Institute1994
Breast, Prostate, Ovarian And Cervical CancerNational Cancer Institute1993