LorraineWareMD

PubMed

• Ascorbate protects human kidney organoids from damage induced by cell-free hemoglobin.
  Julie Bejoy, Justin M Farry, Eddie S Qian, Curtis H Dearing, Lorraine B Ware, Julie A Bastarache, Lauren E Woodard> ;Disease Models & Mechanisms. 2023 Dec 1
• Genomic Variant is Associated with NKG2D-mediated Acute Lung Injury and Death.
  Oscar A Aguilar, Anita E Qualls, Maria D R Gonzalez-Hinojosa, Sarah Obeidalla, V Eric Kerchberger, Tasha Tsao, Jonathan P Singer, Mark R Looney, Wilfred Raymond, Steve...> ;American Journal of Respiratory and Critical Care Medicine. 2023 Oct 25
• Liraglutide pretreatment attenuates sepsis-induced acute lung injury.
  Brandon Baer, Nathan D Putz, Kyle Riedmann, Samantha Gonski, Jason Lin, Lorraine B Ware, Shinji Toki, R Stokes Peebles Jr, Katherine N Cahill, Julie A Bastarache> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2023 Sep 1
• 1 citations
  Identifying molecular phenotypes in sepsis: an analysis of two prospective observational cohorts and secondary analysis of two randomised controlled trials.
  Pratik Sinha, V Eric Kerchberger, Andrew Willmore, Julia Chambers, Hanjing Zhuo, Jason Abbott, Chayse Jones, Nancy Wickersham, Nelson Wu, Lucile Neyton, Charles R Lang...> ;The Lancet. Respiratory Medicine. 2023 Nov 1
• 9 citations
  A New Global Definition of Acute Respiratory Distress Syndrome.
  Michael A Matthay, Yaseen Arabi, Alejandro C Arroliga, Gordon Bernard, Andrew D Bersten, Laurent J Brochard, Carolyn S Calfee, Alain Combes, Brian M Daniel, Niall D Fe...> ;American Journal of Respiratory and Critical Care Medicine. 2023 Jul 24
• Genome-wide Association Study for AKI.
  Pavan K Bhatraju, Ian B Stanaway, Melody R Palmer, Rajasree Menon, Jennifer A Schaub, Steven Menez, Anand Srivastava, F Perry Wilson, Krzysztof Kiryluk, Paul M Palevsk...> ;Kidney360. 2023 Jul 1
• 2 citations
  TRPC6 inhibitor (BI 764198) to reduce risk and severity of ARDS due to COVID-19: a phase II randomised controlled trial.
  Lorraine B Ware, Nima Soleymanlou, Danny Francis McAuley, Vicente Estrada, George A Diaz, Peter Lacamera, Renee Kaste, Wansuk Choi, Abhya Gupta, Tobias Welte> ;Thorax. 2023 Aug 1
• Improving Acute Respiratory Distress Syndrome Diagnosis: Is Lung Ultrasound the Answer?
  Lorraine B Ware> ;American Journal of Respiratory and Critical Care Medicine. 2023 Jun 15
• 2 citations
  Hemoglobin increases leukocyte adhesion and initiates lung microvascular endothelial activation via Toll-like receptor 4 signaling.
  Adrienne K Conger, Toria Tomasek, Kyle J Riedmann, Joel S Douglas, Lucia E Berkey, Lorraine B Ware, Julie A Bastarache, Jamie E Meegan> ;American Journal of Physiology. Cell Physiology. 2023 Mar 1
• 1 citations
  Transpulmonary generation of cell-free hemoglobin contributes to vascular dysfunction in pulmonary arterial hypertension via dysregulated clearance mechanisms.
  Jamie E Meegan, Vern Eric Kerchberger, Niki L Fortune, Joel Brennan McNeil, Julie A Bastarache, Eric D Austin, Lorraine B Ware, Anna R Hemnes, Evan L Brittain> ;Pulmonary Circulation. 2023 Jan 1
• 1 citations
  NLRP3 inflammasome activation in cigarette smoke priming for Pseudomonas aeruginosa-induced acute lung injury.
  Alexis White, Zhengke Wang, Xing Wang, Michelle King, Cynthia Guo, Chris Mantsounga, Alfred Ayala, Alan R Morrison, Gaurav Choudhary, Frank Sellke, Eboni Chambers, Lor...> ;Redox Biology. 2022 Nov 1
• 6 citations
  Association between in-ICU red blood cells transfusion and 1-year mortality in ICU survivors.
  Alice Blet, Joel B McNeil, Julie Josse, Bernard Cholley, Raphaël Cinotti, Gad Cotter, Agnès Dauvergne, Beth Davison, Kévin Duarte, Jacques Duranteau, Marie-Céline Four...> ;Critical Care. 2022 Oct 7
• 9 citations
  Opportunities for improved clinical trial designs in acute respiratory distress syndrome.
  Katherine D Wick, Neil R Aggarwal, Martha A Q Curley, Alpha A Fowler 3rd, Samir Jaber, Maciej Kostrubiec, Nathalie Lassau, Pierre François Laterre, Guillaume Lebreton,...> ;The Lancet. Respiratory Medicine. 2022 Sep 1
• 6 citations
  Contemporary trends in PGD incidence, outcomes, and therapies.
  Edward Cantu, Joshua M Diamond, Marisa Cevasco, Yoshi Suzuki, Maria Crespo, Emily Clausen, Laura Dallara, Christian V Ramon, Michael T Harmon, Christian Bermudez, Luke...> ;The Journal of Heart and Lung Transplantation. 2022 Dec 1
• 13 citations
  Pulse oximetry for the diagnosis and management of acute respiratory distress syndrome.
  Katherine D Wick, Michael A Matthay, Lorraine B Ware> ;The Lancet. Respiratory Medicine. 2022 Nov 1
• Ultraviolet light oxidation of fresh hemoglobin eliminates aggregate formation seen in commercially sourced hemoglobin.
  Aqeela Afzal, William N Beavers, Eric P Skaar, Margaret C Calhoun, Kelly A Richardson, Stuart R Landstreet, David E Cliffel, David Wright, Julie A Bastarache, Lorraine...> ;Blood Cells, Molecules & Diseases. 2023 Jan 1
• 8 citations
  An Iron Refractory Phenotype in Obese Adipose Tissue Macrophages Leads to Adipocyte Iron Overload.
  Magdalene K Ameka, William N Beavers, Ciara M Shaver, Lorraine B Ware, Vern Eric Kerchberger, Kelly Q Schoenfelt, Lili Sun, Tatsuki Koyama, Eric P Skaar, Lev Becker, A...> ;International Journal of Molecular Sciences. 2022 Jul 3
• 17 citations
  Use of pragmatic and explanatory trial designs in acute care research: lessons from COVID-19.
  Jonathan D Casey, Laura M Beskow, Jeremy Brown, Samuel M Brown, Étienne Gayat, Michelle Ng Gong, Michael O Harhay, Samir Jaber, Jacob C Jentzer, Pierre-François Laterr...> ;The Lancet. Respiratory Medicine. 2022 Jul 1
• 14 citations
  Multiplatform Single-Cell Analysis Identifies Immune Cell Types Enhanced in Pulmonary Fibrosis.
  Ana P M Serezani, Bruno D Pascoalino, Julia M R Bazzano, Katherine N Vowell, Harikrishna Tanjore, Chase J Taylor, Carla L Calvi, A Scott McCall, Matthew D Bacchetta, C...> ;American Journal of Respiratory Cell and Molecular Biology. 2022 Jul 1
• 2 citations
  Upcoming and urgent challenges in critical care research based on COVID-19 pandemic experience.
  Franck Verdonk, Dorien Feyaerts, Rafael Badenes, Julie A Bastarache, Adrien Bouglé, Wesley Ely, Brice Gaudilliere, Christopher Howard, Katarzyna Kotfis, Alexandre Laut...> ;Anaesthesia, Critical Care & Pain Medicine. 2022 Oct 1
• 3 citations
  Secretory Cells Are the Primary Source of pIgR in Small Airways.
  Jessica B Blackburn, Jacob A Schaff, Sergey Gutor, Rui-Hong Du, David Nichols, Taylor Sherrill, Austin J Gutierrez, Matthew K Xin, Nancy Wickersham, Yong Zhang, Michae...> ;American Journal of Respiratory Cell and Molecular Biology. 2022 Sep 1
• 7 citations
  New Insights into Clinical and Mechanistic Heterogeneity of the Acute Respiratory Distress Syndrome: Summary of the Aspen Lung Conference 2021.
  Thomas R Martin, Rachel L Zemans, Lorraine B Ware, Eric P Schmidt, David W H Riches, Lisa Bastarache, Carolyn S Calfee, Tushar J Desai, Susanne Herold, Catherine L Hou...> ;American Journal of Respiratory Cell and Molecular Biology. 2022 Sep 1
• Blocking P2X7 receptor with AZ 10606120 exacerbates vascular hyperpermeability and inflammation in murine polymicrobial sepsis.
  Jamie E Meegan, Padmini Komalavilas, Joyce Cheung-Flynn, Tsz Wing Yim, Nathan D Putz, Jordan J Jesse, Kyle D Smith, Tatiana N Sidorova, Han Noo Ri Lee, Toria Tomasek, ...> ;Physiological Reports. 2022 Jun 1
• 4 citations
  Design and Rationale of the Sevoflurane for Sedation in Acute Respiratory Distress Syndrome (SESAR) Randomized Controlled Trial.
  Raiko Blondonnet, Laure-Anne Simand, Perine Vidal, Lucile Borao, Nathalie Bourguignon, Dominique Morand, Lise Bernard, Laurence Roszyk, Jules Audard, Thomas Godet, Ant...> ;Journal of Clinical Medicine. 2022 May 16
• 5 citations
  Characterization of Immunopathology and Small Airway Remodeling in Constrictive Bronchiolitis.
  Sergey S Gutor, Bradley W Richmond, Rui-Hong Du, Pingsheng Wu, Jae Woo Lee, Lorraine B Ware, Ciara M Shaver, Sergey V Novitskiy, Joyce E Johnson, John H Newman, Stephe...> ;American Journal of Respiratory and Critical Care Medicine. 2022 Aug 1
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Journal Articles

• Assembly of a Pan-Genome from Deep Sequencing of 910 Humans of African Descent  
  James G Wilson, Rachel M Sherman, Victor E Ortega, Jean G Ford, Christopher O Olopade, Nadia N Hansel, Olufunmilayo Olopade, Esteban G Burchard, Lorraine B Ware, Tina ..., Nature