Louise D McCullough MD PhD

Vascular Neurology

Chair of Neurology UTHealth Houston and McGovern Medical School AVP UTHealth Neurosciences

UT Physicians-Neurology; UTHealth Neurosciences6410 Fannin St Ste 1014Houston, TX 77030
Phone+1 832-325-7080
Fax+1 713-512-2239

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Summary

Dr. Louise McCullough is a neurologist in Houston, TX and is affiliated with multiple hospitals in the area, including University of Texas Health Science Center at Houston, Memorial Hermann - Texas Medical Center, and TIRR Memorial Hermann. She received her medical degree from University of Connecticut School of Medicine and has been in practice 21 years. She specializes in vascular neurology and is experienced in general neurology, vascular neurology, cerebrovascular disease, carotid disease, ultrasound, and thrombolytic/EVT therapy for stroke.

Education & Training

Johns Hopkins University School of MedicineFellowship, Stroke and Vascular Disease, 2000 - 2002
Johns Hopkins UniversityChief Residency, Neurology, 1999 - 2000
Johns Hopkins UniversityResidency, Neurology, 1997 - 2000
Johns Hopkins UniversityInternship, Internal Medicine, 1996 - 1997
Uconn School Of MedicineClass of 1996

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Certifications & Licensure

TX State Medical License 2015 - 2027
CT State Medical License 2004 - 2019
MD State Medical License 2000 - 2011
DE State Medical License 2001 - 2002
American Board of Psychiatry and Neurology Neurology
American Board of Psychiatry and Neurology Vascular Neurology

Awards, Honors, & Recognition

American Heart Association Basic Science Award American Heart Association, 2022
American Heart Association/American Stroke Association (AHA/ASA) C. Miller Fisher, MD Neuroscience Visionary Award 2021
Texas Top Doctors 2021

Publications & Presentations

PubMed

A roadmap towards clinical use of molecular biomarkers in acute ischaemic stroke.
Steffen Tiedt, Naomi Vlegels, Konstantinos Dimitriadis, Wenlu Li, Glen C Jickling
Nature Reviews. Neurology. 2026-10-06
Impact of stroke on respiratory function and amyloid-β pathology in Tg-2576 mice.
Yu-Xing Zhang, Ahmad El Hamamy, Zahid Iqbal, Arya Ranjan, Destiny Sumani
Journal of Alzheimer's Disease. 2026-10-01
Cilostazol Treatment for Intracerebral Hemorrhage: Targeting Dural Lymphatics.
Chen-Kai Lan, Wan-Ru Chen, Yung Chia Hsieh, Tze-Yen Lin, Shao-Chun Hsu
Stroke. 2026-10-01

Journal Articles

Taylor RA, Chang CF, Goods BA, Hammond MD, Grory BM, Ai Y, Steinschneider AF, Renfroe SC, Askenase MH, McCullough LD, Kasner SE, Mullen MT, Hafler DA, Love JC, Sansing LH, J Clin Invest, 1/3/2017
A survey of blood pressure parameters after aneurysmal subarachnoid hemorrhage
Brown RJ, Kumar A, McCullough LD, Butler K, Int J Neurosci, 1/29/2016
Age-Associated Resident Memory CD8 T Cells in the Central Nervous System Are Primed To Potentiate Inflammation after Ischemic Brain Injury
Ritzel RM, Crapser J, Patel AR, Verma R, Grenier JM, Chauhan A, Jellison ER, McCullough LD, J Immunol, 1/15/2016

Books/Book Chapters

Handbook Clinical Neurology
Chapter: Chapter 8: Effects of gender and sex steroids on ischemic injury
McCullough LD, Koerner IP, Hurn PD2008
Society for Women's Health Research
Chapter: The Savvy Woman Patient. How and Why Your Sex Impacts Your Health
McCullough LD and Hurn PDEditors: Phyllis Greenberger, M.S.W., Jennifer Wider, M.D..2006
Stroke
Chapter: Stroke in Women: The effect of Oral Contraceptives and Hormone Replacement on Stroke Risk
Cortese I and McCullough LDEditors: R. Wityk and RH Llinas.American College of Physicians Publishing2006

Lectures

Age and Sex Are Critical Factors in Ischemic Stroke Pathology
Farmington, CT - 2/11/2014
Aging and Neuroinflammation
Austin, TX - 1/1/2016
Modeling Stroke in the Laboratory
Houston, TX - 1/1/2016

Authored Content

Dendrimer Nanotherapy for Severe COVID-19 Attenuates Inflammation and Neurological Injury Markers and Improves Outcomes in a Phase2a Clinical TrialJuly 2022

Press Mentions

Follow Your Gut: How Research into the Gut-Brain Axis Could Unlock New TherapiesJune 11th, 2025
Gut Bacteria Imbalance After Stroke May Worsen Brain Inflammation TodayheadlineMarch 25th, 2025
GFAP Biomarker Assay Can Discern ICH vs Ischemic StrokeFebruary 11th, 2025

Grant Support

Sex Differences in Inflammation Across the LifespanUNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON2023–2031
Sex specific immune response to SARS-CoV-2 leads to chronic neurologic symptomsUNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON2021–2026
Stroke Disordered Breathing and its Impact on Cognitive Decline in Aging, Alzheimer's Disease and Cerebral Amyloid AngiopathyUNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON2020–2025
Maternal Factors Influencing Trans-Generational Stroke RiskAHA MERIT Award2020–2025
Detrimental Effects of Age Related DysbiosisNIH/NINDS2018–2023