LouiseDMcCulloughMDPhD

PubMed

• Sex Differences in Perihematomal Edema Volume and Outcome After Intracerebral Hemorrhage.
  Cao, Q., Luo, Y., Messé, S., Mayer, S., Witsch, J., Song, J., Sloane, K., Rothstein, A., Favilla, C., Cucchiara, B., Kasner, S., Choi, H., McCullough, L., Gusdon, A.> ;Neurocritical Care. 2024 Feb 20
• Mapping brain-immune interactions in ischemic stroke.
  Jiang, D., McCullough, L.> ;Nature Immunology. 2024 Mar 1
• Neutrophils and Neutrophil Extracellular Traps Cause Vascular Occlusion and Delayed Cerebral Ischemia After Subarachnoid Hemorrhage in Mice.
  Hong, S., Peesh, P., Dienel, A., Torres, K., Thankamani Pandit, P., Matsumura, K., Huang, S., Li, W., Chauhan, A., Marrelli, S., Aronowski, J., McBride, D., Zeineddine...> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2024 Mar 1
• Stroke and the Microbiome.
  Banerjee, A., Mohapatra, S., McCullough, L.> ;Stroke. 2024 Mar 1
• The contribution of age-related changes in the gut-brain axis to neurological disorders.
  Khan, R., Di Gesù, C., Lee, J., McCullough, L.> ;Gut Microbes. 2024 Jan 18
• Brain endothelial CD200 signaling protects brain against ischemic damage.
  Afzal Misrani, Conelius Ngwa, Abdullah Al Mamun, Romana Sharmeen, Kanaka Valli Manyam, Rodney M Ritzel, Louise McCullough, Fudong Liu> ;Brain Research Bulletin. 2024 Feb 1
• Estradiol mediates colonic epithelial protection in aged mice after stroke and is associated with shifts in the gut microbiome.
  Juneyoung Lee, Pedram Peesh, Victoria Quaicoe, Chunfeng Tan, Anik Banerjee, Patrick Mooz, Bhanu P Ganesh, Joseph Petrosino, Robert M Bryan Jr, Louise D McCullough, Ven...> ;Gut Microbes. 2023 Dec 1
• Stabilizing histamine release in gut mast cells mitigates peripheral and central inflammation after stroke.
  Maria P Blasco Conesa, Frank W Blixt, Pedram Peesh, Romeesa Khan, Janelle Korf, Juneyoung Lee, Gayathri Jagadeesan, Alexander Andersohn, Tushar K Das, Chunfeng Tan, Cl...> ;Journal of Neuroinflammation. 2023 Oct 7
• 10 citations
  A multi-laboratory preclinical trial in rodents to assess treatment candidates for acute ischemic stroke.
  Patrick D Lyden, Márcio A Diniz, Francesca Bosetti, Jessica Lamb, Karisma A Nagarkatti, André Rogatko, Sungjin Kim, Ryan P Cabeen, James I Koenig, Kazi Akhter, Ali S A...> ;Science Translational Medicine. 2023 Sep 20
• 2 citations
  Automated Large Vessel Occlusion Detection Software and Thrombectomy Treatment Times: A Cluster Randomized Clinical Trial.
  Juan Carlos Martinez-Gutierrez, Youngran Kim, Sergio Salazar-Marioni, Muhammad Bilal Tariq, Rania Abdelkhaleq, Arash Niktabe, Anjan N Ballekere, Ananya S Iyyangar, Mai...> ;JAMA Neurology. 2023 Nov 1
• The murky waters of sex differences in post-stroke cognitive impairment.
  Louise D McCullough> ;Nature Reviews. Neurology. 2023 Nov 1
• 3 citations
  Iron overload induces cerebral endothelial senescence in aged mice and in primary culture in a sex-dependent manner.
  Brian Noh, Maria Pilar Blasco-Conesa, Syed Mushfiqur Rahman, Sheelu Monga, Rodney Ritzel, Gary Guzman, Yun-Ju Lai, Bhanu Priya Ganesh, Akihiko Urayama, Louise D McCull...> ;Aging Cell. 2023 Nov 1
• A narrative review on treatment strategies for neonatal hypoxic ischemic encephalopathy.
  Janelle M Korf, Louise D McCullough, Viola Caretti> ;Translational Pediatrics. 2023 Aug 30
• Pirh2-dependent DNA damage in neurons induced by the G-quadruplex ligand pyridostatin.
  Rocio Diaz Escarcega, Abhijeet A Patil, Jose F Moruno-Manchon, Akihiko Urayama, Sean P Marrelli, Nayun Kim, David Monchaud, Louise D McCullough, Andrey S Tsvetkov> ;The Journal of Biological Chemistry. 2023 Oct 1
• 1 citations
  Women With Large Vessel Occlusion Acute Ischemic Stroke Are Less Likely to Be Routed to Comprehensive Stroke Centers.
  Muhammad Bilal Tariq, Iman Ali, Sergio Salazar-Marioni, Ananya S Iyyangar, Hussain M Azeem, Swapnil Khose, Victor Lopez, Rania Abdelkhaleq, Louise D McCullough, Sunil ...> ;Journal of the American Heart Association. 2023 Jul 18
• Sex Differences in the Evaluation and Treatment of Stroke.
  Sonia K Singh, Louise McCullough> ;Handbook of Experimental Pharmacology. 2023 Jan 1
• Role of the Meningeal Lymphatics in Stroke.
  Maharajni Perla, Viola Caretti, María A Moro, Louise D McCullough> ;Stroke. 2023 Jun 1
• 7 citations
  Contemporary Antiplatelet and Anticoagulant Therapies for Secondary Stroke Prevention: A Narrative Review of Current Literature and Guidelines.
  Kunal Bhatia, Lindsey M Ladd, Kelsey H Carr, Mario Di Napoli, Jeffrey L Saver, Louise D McCullough, Maryam Hosseini Farahabadi, Diana L Alsbrook, Archana Hinduja, Jorg...> ;Current Neurology and Neuroscience Reports. 2023 May 1
• 1 citations
  Unfractionated heparin versus enoxaparin for venous thromboembolism prophylaxis in intensive care units: a propensity score adjusted analysis.
  Sophie Samuel, Wen Li, Koren Dunn, Jennifer Cortes, Thuy Nguyen, Daniel Moussa, Abhay Kumar, Thanh Dao, James Beeson, H Alex Choi, Louise D McCullough> ;Journal of Thrombosis and Thrombolysis. 2023 May 1
• Heterochronic Parabiosis Causes Dacryoadenitis in Young Lacrimal Glands.
  Kaitlin K Scholand, Alexis F Mack, Gary U Guzman, Michael E Maniskas, Ritu Sampige, Gowthaman Govindarajan, Louise D McCullough, Cintia S de Paiva> ;International Journal of Molecular Sciences. 2023 Mar 3
• 2 citations
  The Tardigrade damage suppressor protein Dsup promotes DNA damage in neurons.
  Rocio Diaz Escarcega, Abhijeet A Patil, Matthew D Meyer, Jose F Moruno-Manchon, Alexander D Silvagnoli, Louise D McCullough, Andrey S Tsvetkov> ;Molecular and Cellular Neurosciences. 2023 Jun 1
• 1 citations
  MicroRNA Profiles in Intestinal Epithelial Cells in a Mouse Model of Sepsis.
  Siqingaowa Caidengbate, Yuichi Akama, Anik Banerjee, Khwanchanok Mokmued, Eiji Kawamoto, Arong Gaowa, Louise D McCullough, Motomu Shimaoka, Juneyoung Lee, Eun Jeong Park> ;Cells. 2023 Feb 24
• 10 citations
  Mitochondria-containing extracellular vesicles (EV) reduce mouse brain infarct sizes and EV/HSP27 protect ischemic brain endothelial cultures.
  Kandarp M Dave, Donna B Stolz, Venugopal R Venna, Victoria A Quaicoe, Michael E Maniskas, Michael John Reynolds, Riyan Babidhan, Duncan X Dobbins, Maura N Farinelli, A...> ;Journal of Controlled Release. 2023 Feb 1
• 3 citations
  Upregulation of PD-L1 by SARS-CoV-2 promotes immune evasion.
  Hsiang-Chi Huang, Shih-Han Wang, Guo-Chen Fang, Wen-Cheng Chou, Chun-Che Liao, Cheng-Pu Sun, Jia-Tsrong Jan, Hsiu-Hua Ma, Hui-Ying Ko, Yi-An Ko, Ming-Tsai Chiang, Jian...> ;Journal of Medical Virology. 2023 Feb 1
• Middle Cerebral Artery Occlusion in Aged Animal Model.
  Grant W Goodman, Justin N Nguyen, Frank W Blixt, Michael E Maniskas, Louise D McCullough, Anjali Chauhan> ;Methods in Molecular Biology. 2023 Jan 1
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Journal Articles

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  Taylor RA, Chang CF, Goods BA, Hammond MD, Grory BM, Ai Y, Steinschneider AF, Renfroe SC, Askenase MH, McCullough LD, Kasner SE, Mullen MT, Hafler DA, Love JC, Sansing LH, J Clin Invest, 1/3/2017
• A survey of blood pressure parameters after aneurysmal subarachnoid hemorrhage  
  Brown RJ, Kumar A, McCullough LD, Butler K, Int J Neurosci, 1/29/2016
• Age-Associated Resident Memory CD8 T Cells in the Central Nervous System Are Primed To Potentiate Inflammation after Ischemic Brain Injury  
  Ritzel RM, Crapser J, Patel AR, Verma R, Grenier JM, Chauhan A, Jellison ER, McCullough LD, J Immunol, 1/15/2016
• Early retinal inflammatory biomarkers in the middle cerebral artery occlusion model of ischemic stroke  
  Ritzel RM, Pan SJ, Verma R, Wizeman J, Crapser J, Patel AR, Lieberman R, Mohan R, McCullough LD, Mol. Vis., 1/4/2016
• Nuclear translocation of histone deacetylase 4 induces neuronal death in stroke  
  Yuan H, Denton K, Liu L, Li XJ, Benashski S, McCullough L, Li J, Neurobiol Dis, 1/1/2016
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  Liu L, Yuan H, Denton K, Li XJ, McCullough L, Li J, Eur J Neurosci, 1/1/2016
• Pre-stroke Living Situation and Depression Contribute to Initial Stroke Severity and Stroke Recovery  
  Aron A, Staff I, Fortunato G, McCullough LD, J Stroke Cerebrovasc Dis, 1/1/2015
• Immunologic Modulations to Enhance Post-Stroke Recovery  
  Howe MD and McCullough LD, Current Immunology Reviews, 1/1/2015
• Sex differences in ischemic stroke are influenced by gonadal hormones, not by sex chromosome complement  
  Manwani B, Venna V, Benashki S, Arnold A, McCullough LD, J Cereb Blood Flow Metab, 1/1/2015
• Ultrasonic Vocalization Changes and FOXP2 expression after Experimental Stroke  
  Doran S, Trammel C,Benashaski S, Venna V; McCullough LD, Behav Brain Res, 1/1/2015
• Sex Differences and the Role of IL-10 in Ischemic Stroke Recovery  
  Conway SE, Roy-O'Reilly M, Friedler B, Staff I, Fortunato G, McCullough LD, Biology of Sex Differences, 1/1/2015
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  Venna VR, Benashski SE, Chauhan A, McCullough LD, Learn Mem, 1/1/2015
• Age- and Location-Related Changes in Microglia Function  
  Ritzel RM, Patel AR, Pan S, Crapser J, Hammond M, Jellison E, McCullough LD, Neurobiol Aging, 1/1/2015
• Peripheral Nerve Regeneration Strategies: Electrically Stimulating Polymer Based Nerve Growth Conduits  
  Anderson M, Shelke NB, Manoukian OS, Yu X, McCullough LD, Kumbar SG, Critical Reviews in Biomedical Engineering, 1/1/2015
• One is the deadliest number: the detrimental effects of social isolation on cerebrovascular diseases and cognition  
  Friedler B, Crapser J, McCullough L, Acta Neuropathol, 1/24/2014
• Stroke prevention in women: synopsis of the 2014 American Heart Association/American Stroke Association guideline  
  Bushnell C, McCullough L, Ann Intern Med, 1/1/2014
• Genetic deletion of calcium/calmodulin-dependent protein kinase kinase beta (CaMKK beta) or CaMK IV exacerbates stroke outcomes in ovariectomized (OVXed) female mice  
  Liu L. McCullough LD, Li J, BMC Neurosci, 1/1/2014
• Pair housing reverses post-stroke depressive behavior in mice  
  Verma R, Friedler BD, Harris NM, McCullough LD, Behav Brain Res, 1/1/2014
• Sex Differences in Stroke: The Contribution of Coagulation  
  Roy-O'Reilly M, McCullough LD, Exp Neurol, 1/1/2014
• The middle cerebral artery occlusion model of transient focal cerebral ischemia  
  Liu F, McCullough LD, Methods Mol Biol, 1/1/2014
• Social interaction plays a critical role in neurogenesis and recovery after stroke  
  Venna V, Xu Y, Doran S, Patrizz A McCullough LD, Translational Psychiatry, 1/1/2014
• Chronic metformin treatment improves post-stroke angiogenesis and recovery after experimental stroke  
  Venna VR, Li J, Hammond MD, Mancini NS, McCullough LD, Eur J Neurosci, 1/1/2014
• Inhibition of mitogen-activated protein kinase phosphatase-1 (MKP-1) increases experimental stroke injury  
  Liu L, Doran S, Xu Y, Manwani B, Ritzel R, Benashski S, McCullough L, Li J, Exp Neurol, 1/1/2014
• CCR2+Ly6Chi inflammatory monocyte recruitment exacerbates acute disability following intracerebral hemorrhage  
  Hammond MD, Taylor RA, Mullen MT, Ai Y, Aguila HL, Kasner SE, McCullough LD, Sansing LH, J Neurosci, 1/1/2014
• Guidelines for the Prevention of Stroke in Women: A Statement for Healthcare Professionals from the American Heart Association/American Stroke Association Council on S...  
  Bushnell C (Chair); McCullough LD, (Vice-Chair); Awad IS; Chireau MV; Fedder WN; Furie KL; Howard VJ; Lichtman JH; Lisabeth LD; Piña IL, Reeves MJ; Rexrode KM; Sapos..., Stroke, 1/1/2014
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Books/Book Chapters

• Handbook Clinical Neurology 
  Chapter: Chapter 8: Effects of gender and sex steroids on ischemic injury 
  McCullough LD, Koerner IP, Hurn PD2008
• Society for Women's Health Research 
  Chapter: The Savvy Woman Patient. How and Why Your Sex Impacts Your Health 
  McCullough LD and Hurn PDEditors: Phyllis Greenberger, M.S.W., Jennifer Wider, M.D..2006
• Stroke 
  Chapter: Stroke in Women: The effect of Oral Contraceptives and Hormone Replacement on Stroke Risk 
  Cortese I and McCullough LDEditors: R. Wityk and RH Llinas.American College of Physicians Publishing2006
• Stroke 
  Chapter: Intravenous and Intra-arterial TPA for Acute Stroke 
  Blakely J, Llinas, RH, McCullough, LDEditors: R. Wityk and RH Llinas.American College of Physicians Publishing2006
• Acute Stroke: Bench to Bedside 
  Chapter: Gender differences in stroke pathobiology: Therapeutic implications 
  McCullough LD, Kofler J, Hurn PDEditors: Bhardwaj A.Marcel Dekker Publishing, New York2006
• Pharmacology of Cerebral Ischemia 
  Chapter: Estrogen and Testosterone as Neuroprotectants in Stroke 
  Hurn PD, Ardelt AA, Alkayed NJ, Crain BJ, Hu W, Kearney ML, McCullough LD, Murphy SJ, Toung TJK, Traystman RJ, Wang MMEditors: Krieglstein J.Medpharm Scientific Publishers, Stuttgart, Germany2002
• Yearbook of Intensive Care Medicine and Emergency Medicine 
  Chapter: Cerebral Ischemia: Pathophysiology and Neuroprotection 
  Hurn PD, Alkayed NJ, Bhardwaj A, Koehler RC, Kirsch JR, Littleton-Kearney MT, McCullough LD, Murphy SJ, Rossberg MI, Toung TJ & Traystman RJEditors: Vincent, JL.Springer-Verlag Publishing, Heidelberg2001
• Intima Media Thickness: Watching the Arterial Risk 
  Chapter: Vascular effects of estrogen in experimental stroke 
  Alkayed, NJ, McCullough LD, Littleton-Kearney M., Rusa R., Sampei, K., Sawada M., Goto S., Watanabe Y., Toung TJK, Crain BJ, Traystman RJ & Hurn, P.D.Editors: P-J Touboul.2001
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Lectures

• Age and Sex Are Critical Factors in Ischemic Stroke Pathology 
  Farmington, CT - 2/11/2014
• Prevention of stroke in women and unique risk factors in women 
  University of Washington - 1/1/2016
• Manipulating the Inflammatory Response to Stroke in Aged Animals 
  Quebec, Canada - 1/1/2016
• Modeling Stroke in the Laboratory 
  Houston, TX - 1/1/2016
• Aging and Neuroinflammation 
  Austin, TX - 1/1/2016
• Sex Matters: Why we should still care about STAIR 
  Nashville, TN - 1/1/2015
• Translational stroke research: The effects of age and sex 
  The Jackson Laboratory, Bar Harbor, ME - 1/1/2015
• Age and Sex Are Critical Factors in Ischemic Stroke Pathology 
  Farmington, CT - 2/13/2014
• Age and Sex Are Critical Factors in Ischemic Stroke Pathology 
  Avon, CT - 2/13/2014
• Translational Stroke Research 
  Cedars Sinai - 1/1/2014
• Preclinical Animal Models 
  1/1/2014
• Animal Models and Translation to Clinical Trials 
  1/1/2014
• The influence of Age and Sex in Stroke Research 
  West Virginia University - 1/1/2014
• Stroke Update 2014 
  St Francis Hospital - 1/1/2014
• Social Isolation and Stroke 
  National Institute of Health - 1/1/2014
• Stroke Syndromes: How to Recognize Them 
  1/1/2014
• Bridging Basic and Clinical Research 
  1/1/2014
• Stroke update 2013 
  University of Connecticut Health Center - 1/1/2013
• Stroke Outcomes in Women 
  Duke University - 1/1/2013
• Stroke: Clinical and Basic Science of Sex Differences 
  Mt Sinai Hospital New York - 1/1/2012
• AMPK as a target for Stroke Treatment 
  Monterey CA - 1/1/2012
• Social Isolation in Stroke 
  University of Connecticut - 1/1/2012
• Stroke and TIA update 
  University of Connecticut - 1/1/2011
• Careers in Medicine 
  University of Connecticut, Storrs CT - 1/1/2011
• Sex Differences in Stroke 
  1/1/2011
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