LucasRaphaelHoffmanMDPhD

PubMed

• Alterations in the fecal microbiota in patients with advanced cystic fibrosis liver disease after 6 months of elexacaftor/tezacaftor/ivacaftor.
  Jennifer T Duong, Christopher E Pope, Hillary S Hayden, Carson Miller, Stephen J Salipante, Steven M Rowe, George M Solomon, David Nichols, Lucas R Hoffman, Michael R ...> ;Journal of Cystic Fibrosis. 2024 Mar 6
• 1 citations
  Antibiotic Regimen Changes during Cystic Fibrosis Pediatric Pulmonary Exacerbation Treatment.
  Jonathan D Cogen, Don B Sanders, James E Slaven, Anna V Faino, Ranjani Somayaji, Ron L Gibson, Lucas R Hoffman, Clement L Ren> ;Annals of the American Thoracic Society. 2023 Sep 1
• 1 citations
  Polymicrobial infections and antibiotic treatment patterns for cystic fibrosis pulmonary exacerbations.
  Anna V Faino, Lucas R Hoffman, Ronald L Gibson, Matthew P Kronman, David P Nichols, Margaret Rosenfeld, Jonathan D Cogen> ;Journal of Cystic Fibrosis. 2023 Jul 1
• 3 citations
  Clinical Outcomes of Antipseudomonal versus Other Antibiotics among Children with Cystic Fibrosis without.
  Jonathan D Cogen, Anna V Faino, Frankline Onchiri, Ronald L Gibson, Lucas R Hoffman, David P Nichols, Margaret Rosenfeld, Matthew P Kronman> ;Annals of the American Thoracic Society. 2022 Aug 1
• 11 citations
  Thymidine starvation promotes c-di-AMP-dependent inflammation during pathogenic bacterial infection.
  Qing Tang, Mimi R Precit, Maureen K Thomason, Sophie F Blanc, Fariha Ahmed-Qadri, Adelle P McFarland, Daniel J Wolter, Lucas R Hoffman, Joshua J Woodward> ;Cell Host & Microbe. 2022 Jul 13
• 107 citations
  Clinical Effectiveness of Elexacaftor/Tezacftor/Ivacaftor in People with Cystic Fibrosis.
  David P. Nichols, Alex C Paynter, Sonya L. Heltshe, Scott H. Donaldson, Carla A. Frederick, Steven D. Freedman, Daniel Gelfond, Lucas R. Hoffman, Andrea Kelly, Michael...> ;American Journal of Respiratory and Critical Care Medicine. 2021 Nov 16
• 5 citations
  Infants with cystic fibrosis have altered fecal functional capacities with potential clinical and metabolic consequences
  Alexander Eng, Hillary S. Hayden, Christopher E. Pope, Mitchell J. Brittnacher, Anh T. Vo, Eli J. Weiss, Kyle R. Hager, Daniel H. Leung, Sonya L. Heltshe, Daniel Rafte...> ;BMC Microbiology. 2021 Sep 1
• 16 citations
  The role of Psl in the failure to eradicate Pseudomonas aeruginosa biofilms in children with cystic fibrosis.
  Amanda J Morris, Lindsay Jackson, Yvonne C. W. Yau, Courtney Reichhardt, Trevor Beaudoin, Stephanie Uwumarenogie, Kevin M. Guttman, P. Lynne Howell, Matthew R. Parsek,...> ;NPJ Biofilms and Microbiomes. 2021 Aug 4
• 8 citations
  Association Between Number of Intravenous Antipseudomonal Antibiotics and Clinical Outcomes of Pediatric Cystic Fibrosis Pulmonary Exacerbations
  Jonathan D Cogen, Anna V. Faino, Frankline Onchiri, Lucas R. Hoffman, Matthew P. Kronman, David P. Nichols, Margaret Rosenfeld, Ronald L. Gibson> ;Clinical Infectious Diseases. 2021 Nov 2
• 8 citations
  Phenotypic characteristics of incident and chronic MRSA isolates in cystic fibrosis
  Deirdre Gilpin, Lucas R. Hoffman, Agathe Ceppe, Marianne S. Muhlebach> ;Journal of Cystic Fibrosis. 2021 Jun 6
• 2 citations
  Gastrointestinal Factors Associated With Hospitalization in Infants With Cystic Fibrosis: Results From the Baby Observational and Nutrition Study.
  Meghana Sathe, Rong Huang, Sonya L. Heltshe, Alexander Eng, Elhanan Borenstein, Samuel I. Miller, Lucas R. Hoffman, Daniel Gelfond, Daniel H. Leung, Drucy Borowitz, Bo...> ;Journal of Pediatric Gastroenterology and Nutrition. 2021 May 18
• 7 citations
  Impairment in inflammasome signaling by the chronic Pseudomonas aeruginosa isolates from cystic fibrosis patients results in an increase in inflammatory response.
  Melissa S Phuong, Rafael E Hernandez, Daniel J. Wolter, Lucas R. Hoffman, Subash Sad> ;Cell Death & Disease. 2021 Mar 4
• 35 citations
  PROMISE: Working with the CF community to understand emerging clinical and research needs for those treated with highly effective CFTR modulator therapy.
  Dave P. Nichols, Scott H. Donaldson, Carla A. Frederick, Steven D. Freedman, Daniel Gelfond, Lucas R. Hoffman, Andrea Kelly, Michael R. Narkewicz, Jessica E. Pittman, ...> ;Journal of Cystic Fibrosis. 2021 Mar 1
• 6 citations
  Effect of Concomitant Azithromycin and Tobramycin Use on Cystic Fibrosis Pulmonary Exacerbation Treatment.
  Jonathan D Cogen, Anna V. Faino, Frankline Onchiri, Ronald L. Gibson, Lucas R. Hoffman, Matthew P. Kronman, Margaret Rosenfeld, David P. Nichols> ;Annals of the American Thoracic Society. 2021 Feb 1
• 6 citations
  Characterization of cerebrospinal fluid (CSF) microbiota from patients with CSF shunt infection and reinfection using high throughput sequencing of 16S ribosomal RNAge...
  Kathryn B. Whitlock, Christopher E. Pope, Paul Hodor, Lucas R. Hoffman, David L. Limbrick, Patrick J. McDonald, Jason S. Hauptman, Jeffrey G. Ojemann, Tamara D. Simon> ;Plos One. 2021 Jan 6
• 4 citations
  Molecular Characterization of Microbiota in Cerebrospinal Fluid From Patients With CSF Shunt Infections Using Whole Genome Amplification Followed by Shotgun Sequencing.
  Paul Hodor, Christopher E. Pope, Kathryn B. Whitlock, Lucas R. Hoffman, David L. Limbrick, Patrick J. McDonald, Jason S. Hauptman, Jeffrey G. Ojemann, Tamara D. Simon> ;Frontiers in Cellular and Infection Microbiology. 2021 Jan 1
• 16 citations
  Changes in fecal microbiota with CFTR modulator therapy: A pilot study.
  Charles E. Pope, Anh T. Vo, Hillary S. Hayden, Eli J. Weiss, S.L. Durfey, Sharon McNamara, Anina Ratjen, B. Grogan, S. Carter, L. Nay, Parsek, Pradeep K. Singh, Edward...> ;Journal of Cystic Fibrosis. 2021 Sep 1
• 17 citations
  Polyclonality, Shared Strains, and Convergent Evolution in Chronic Cystic Fibrosis Staphylococcus aureus Airway Infection
  Dustin R. Long, Daniel J. Wolter, Michael Lee, Mimi R. Precit, Kathryn McLean, Elizabeth E. Holmes, Kelsi Penewit, Adam Waalkes, Lucas R. Hoffman, Stephen J. Salipante> ;American Journal of Respiratory and Critical Care Medicine. 2020 Dec 9
• 3 citations
  Repeated isolation of an antibiotic-dependent and temperature-sensitive mutant of Pseudomonas aeruginosa from a cystic fibrosis patient.
  Daniel J. Wolter, Alison J. Scott, Catherine R. Armbruster, Dale Whittington, John Scott Edgar, Xuan Qin, Anne Marie Buccat, Sharon McNamara, Marcella Blackledge, Adam...> ;The Journal of Antimicrobial Chemotherapy. 2021 Feb 11
• 5 citations
  Association of Inhaled Antibiotics in Addition to Standard Intravenous Therapy and Outcomes of Pediatric Inpatient Pulmonary Exacerbations
  Jonathan D Cogen, Anna V. Faino, Frankline Onchiri, Lucas R. Hoffman, Matthew P. Kronman, Maria T. Nelson, David P. Nichols, Margaret Rosenfeld, Donald R. VanDevanter,...> ;Annals of the American Thoracic Society. 2020 Dec 1
• 9 citations
  Carbapenems drive the collateral resistance to ceftaroline in cystic fibrosis patients with MRSA
  Maria Celeste Varela, Melanie Roch, Agustina Taglialegna, Scott Wesley Long, Matthew Ojeda Saavedra, Warren E. Rose, James J. Davis, Lucas R. Hoffman, Rafael E Hernand...> ;Communications Biology. 2020 Oct 22
• 37 citations
  Elevated exopolysaccharide levels in Pseudomonas aeruginosa flagellar mutants have implications for biofilm growth and chronic infections.
  Joe J. Harrison, Henrik Almblad, Yasuhiko Irie, Daniel J. Wolter, Heather C. Eggleston, Trevor E. Randall, Jacob O. Kitzman, Bethany Stackhouse, Julia Emerson, Sharon ...> ;Plos Genetics. 2020 Jun 12
• 33 citations
  The impact of CFTR modulator therapies on CF airway microbiology.
  Geraint B. Rogers, Steven L. Taylor, Lucas R. Hoffman, Lucy D. Burr> ;Journal of Cystic Fibrosis. 2020 May 1
• 112 citations
  Lung function and microbiota diversity in cystic fibrosis
  Leah Cuthbertson, Alan W. Walker, Anna Oliver, Geraint B. Rogers, Damian W. Rivett, Thomas H. Hampton, Alix Ashare, J. Stuart Elborn, Anthony De Soyza, Mary P. Carroll...> ;Microbiome. 2020 Apr 2
• 45 citations
  CFTR dysregulation drives active selection of the gut microbiome
  Stacey M Meeker, Kevin S Mears, Naseer Sangwan, Mitchell J. Brittnacher, Eli J. Weiss, Piper M. Treuting, Nicholas Tolley, Christopher E. Pope, Kyle R. Hager, Anh T. V...> ;Plos Pathogens. 2020 Jan 21
• Join now to see all

Journal Articles

• Adaptation of Commensal Proliferating Escherichia Coli to the Intestinal Tract of Young Children with Cystic Fibrosis  
  Samuel I Miller, Lucas R Hoffman, Proceedings of the National Academy of Sciences
• Toward making inroads in reducing the disparity of lung health in Australian Indigenous and New Zealand Maori children  
  Chang, AB; Marsh, R; Upham, J; Hoffman, LR; Smith-Vaughan, H; Holt, D; Byrnes, C; Toombs, M; Yerkovich, S; Torzillo, P; Grady, KO; Grimwood, K, Front Pediatr, 1/13/2015
• Implications of multiple freeze-thawing on respiratory samples for culture-independent analyses  
  Cuthbertson, L; Rogers, GB; Walker, AW; Oliver, A; Hoffman, LR; Carroll, MP; Parkhill, J; Bruce, KD; van der Gast, CJ, J Cyst Fibros, 1/1/2015
• The pediatric microbiome and the lung  
  Tracy, M; Cogen, J; Hoffman, LR, Curr Opin Pediatr, 1/1/2015
• Cystic fibrosis mouse model-dependent small intestine structural abnormalities and gut microbiome  
  Bazett, M; Honeyman, L; Stefanov, A; Pope, C; Hoffman, LR; and Haston, C, Mamm Genome, 1/1/2015
• Cystic fibrosis-adapted Pseudomonas aeruginosa quorum sensing lasR mutants cause hyperinflammatory responses  
  LaFayette, S; Beaudoin, T; Hoffman, LR; Burns, JL; Brochiero, E; Rousseau, S; Nguyen, D, Science Advances, 1/1/2015
• Narrowing in on early cystic fibrosis lung disease  
  Zemanick, ET; Hoffman, L; Rosenfeld, M, Am J Respir Crit Care Med, 1/15/2014
• Escherichia coli dysbiosis correlates with gastrointestinal dysfunction in children with cystic fibrosis  
  Hoffman LR, Pope CE, Hayden HS, Heltshe S, Levy R, McNamara S, Jacobs MA, Rohmer L, Radey M, Ramsey BW, Brittnacher MJ, Borenstein E, Miller SI, Clin Infect Dis, 1/1/2014
• Evaluation of bacterial and fungal diversity in cerebrospinal fluid shunt infection  
  Simon, TD; Pope, CE; Browd, SR; Ojemann, JG; Riva-Cambrin, J; Mayer-Hamblett, N; Rosenfeld, M; Zerr, D; and Hoffman, LR, PLoS ONE, 1/1/2014
• Gastrointestinal Pathology in Juvenile and Adult CFTR-Knockout Ferrets  
  Sun, X; Olivier, AK; Yi, Y; Pope, CE; Hayden, HS; Liang, B; Sui, H; Zhou, W; Hager, KR; et al, American Journal of Pathology, 1/1/2014
• Pseudomonas aeruginosa phenotypes associated with eradication failure in children with cystic fibrosis  
  Mayer-Hamblett, N; Ramsey, BW; Kulasekara, H; Wolter, DJ; Houston, LS; Pope, CE; Kulasekara, B; Armbruster, C; Burns, JL; Retsch-Bogart, G; Rosenfeld, M; Gibson, RL; M..., Clin Infect Dis, 1/1/2014
• Pediatric infection and intestinal carriage due to extended spectrum cephalosporin-resistant Enterobacteriaceae  
  Zerr, DM; Qin, X; Oron, A; Adler, AL; Wolter, D; Berry, JE; Hoffman, L; and Weissman, SJ, Antimicrob Agents Chemother, 1/1/2014
• Pseudomonas aeruginosa in vitro phenotypes distinguish cystic fibrosis infection stages and outcomes  
  Mayer-Hamblett, N; Rosenfeld, M; Gibson, RL; Ramsey, BW; Kulasekara, H; Retsch-Bogart, GZ; Morgan, W; Wolter, DJ; Pope, CE; Houston, LS; Kulasekara, B; Khan, U; Burns,..., Am J Respir Crit Care Med, 1/1/2014
• Three clinically distinct chronic pediatric airway infections share a common core microbiota  
  van der Gast, CJ; Cuthbertson, L; Rogers, GB; Pope, C; Marsh, RL; Redding, GJ; Bruce, KD; Chang, AB; Hoffman, LR, Ann Am Thorac Soc, 1/1/2014
• Time between sputum sample collection and storage significantly influences bacterial sequence composition from cystic fibrosis respiratory infections  
  Cuthbertson, L; Rogers, GB; Walker, AW; Oliver, A; Hafiz, T; Hoffman, LR; Carroll, MP; Parkhill, J; Bruce, KD; van der Gast, CJ, J Clin Microbiol, 1/1/2014
• Strength in diversity  
  Wolter, DJ; Hoffman, LR, Cell Host and Microbe, 1/1/2014
• Interpreting infective microbiota: the importance of an ecological perspective  
  Wolter, DJ; Emerson, JC; McNamara, S; Buccat, AM; Qin, X; Cochrane, E; Houston, LS; Rogers, GB; Marsh, P; Prehar, K; Pope, CE; Blackledge, M; Deziel, E; Bruce, KD; Ram..., Clin Infect Dis, 1/28/2013
• Fosfomycin and tobramycin in combination downregulate nitrate reductase genes narG and narH, resulting in increased activity against Pseudomonas aeruginosa under anaer...  
  McCaughey G, Gilpin DF, Schneiders T, Hoffman LR, McKevitt M, Elborn JS, Tunney MM, Antimicrob Agents Chemother, 1/19/2013
• Interpreting infective microbiota: the importance of an ecological perspective  
  Rogers, GB; Hoffman, LR; Carroll, MP; Bruce, KD, Trends in Microbiology, 1/15/2013
• What to expect when you're expectorating: Cystic fibrosis exacerbations and microbiota  
  Hoffman, LR; Surette, M, Annals of the American Thoracic Society, 1/1/2013
• Emerging drugs for bronchiectasis  
  Chang, AB; Marsh, RL; Smith-Vaughan, HC; Hoffman, LR, Expert Opinion on Emerging Drugs, 1/1/2012
• Long-term cultivation-independent microbial diversity analysis demonstrates that bacterial communities infecting the adult cystic fibrosis lung show stability and resi...  
  Stressman, FA; Rogers, GB; van der Gast, CJ; Marsh, P; Vermeer, LS; Carroll, MP; Hoffman, LR; Daniels, TWV; Patel, N; Forbes, N; and Bruce, KD, Thorax, 1/1/2012
• Reducing bias in bacterial community analysis of lower airway respiratory infections  
  Rogers, GB; Cuthbertson, L; Hoffman, LR; Wing, PAC; Pope, C; Hooftman, DAP; Lilley, AK; Oliver, A; Carroll, MP; Bruce, KD; van der Gast, CJ, ISME J, 1/1/2012
• Using bacterial biomarkers to identify early indicators of cystic fibrosis pulmonary exacerbation onset  
  Rogers GB, Hoffman LR, Johnson MW, Mayer-Hamblett N, Schwarze J, Carroll MP, Bruce KD, Expert Rev Mol Diag, 1/1/2011
• Does bacterial density in cystic fibrosis sputum increase prior to pulmonary exacerbation?  
  Stressman, FA; Rogers, GB; Daniels, TWV; Lilley, AK; Marsh, P; Carroll, MP; Hoffman, LR; Jones, G; Allen, CE; Patel, N; Forbes, B; Tuck, A; and Bruce, KD, Journal of Cystic Fibrosis, 1/1/2011
• Join now to see all

Books/Book Chapters

• Structural Biology of Viruses 
  Chapter: Attachment and Entry of Influenza Virus into Host Cells: Pivotal Roles of the Hemagglutinin 
  White, JM; Hoffman, LR; Arevalo, JH; and Wilson, IAEditors: Chiu,W; Burnett, RM; and Garcea, RL.Oxford Press, New York, NY1997
• Options for the Control of Influenza III: Proceedings 
  Chapter: Fusion Mechanism of the Influenza Hemagglutinin: Inhibitor Design 
  Hoffman, LR; White, JM; and Kuntz, IDEditors: Brown, LE; Hampson, AW; and Webster, RG.Elsevier Science, BV, The Netherlands1996

Abstracts/Posters

• Survey of the Treatment of Pediatric Parapneumonic Effusion and Empyema.
  Richards, MK; McAteer, J; Hoffman, L; Kronman, M; Shaw, D; Goldin, AB, International Pediatric Endosurgery Group 25th Annual Congress for Endosurgery in Children, Fukuoka, Japan, 1/27/2016
• Short-term and long-term effects of ivacaftor treatment on sputum microbiota in CF patients with the G551D CFTR mutation.
  Hoffman, L; Pope, C; Jorth, P; Hisert, KB; Welsh, M; Singh, PD; McKone, EF, The 2016 American Thoracic Society International Conference, Am J Respir Crit Care Med, San Francisco, CA, 1/16/2016
• Staphylococcus aureus protein A mediates interspecies interactions at the cell surface of Pseudomonas aeruginosa.
  Armbruster, CR; Mishra, M; Wolter, DJ; Hayden, H; Radey, M; Merrihew, G; Wozniak, DJ; MacCoss, MJ; Parsek, MR; Hoffman, L, The 7th American Society of Microbiology (ASM) Conference on Biofilms, Chicago, IL, 1/29/2015
• An optimized in vitro antibiotic susceptibility testing method for Staphylococcus aureus small colony variants.
  Precit, MR; Wolter, DJ; Griffith, A; Burns, JL; Hoffman, LR, The 38th European Cystic Fibrosis Conference, Brussels, Belgium, 1/11/2015
• Short-term and long-term effects of ivacaftor treatment on sputum microbiota in people with the G551D CFTR mutation.
  Pope, CE; Jorth, P; Hisert, KB; Grogan, B; Gallagher, C; Cooke, G; Donnelly, SC; Welsh, M; Singh, PK; McKone, E; Hoffman, LR, The 38th European Cystic Fibrosis Conference, Journal of Cystic Fibrosis, Brussels, Belgium, 1/11/2015
• Initial and chronic MRSA infection in cystic fibrosis.
  Gilpin, DF; Murdock, S; Hoffman, LR; Vallières, E; McGrath, S; Tunney, MM; Elborn, JS; Muhlebach, MS, Journal of Cystic Fibrosis, Brussels, Belgium, 1/11/2015
• Ivacaftor decreases sputum Pseudomonas density and inflammation in CF patients with G551D mutations.
  Hisert, KB; Cooke, G; Pope, C; Jorth, P; Hoffman, LR; Grogan, B; Launspach, J; Gallagher, C; Welsh, M; Singh, P; McKone, E, The 29th Annual North American Cystic Fibrosis Conference, Pediatric Pulmonology, Phoenix, AZ, 1/10/2015
• Staphylococcus aureus should not be treated aggressively in infants and young children with CF.
  Hoffman, LR, The 29th Annual North American Cystic Fibrosis Foundation Conference (NACFC), Pediatric Pulmonology, Phoenix, AZ, 1/10/2015
• Phenotypic variability of clinical Pseudomonas aeruginosa lasR mutants: A functional analysis of the quorum sensing master regulator.
  Feltner, J; Wolter, DJ; Pope, CE: Mayer-Hamblett, N; Hoffman, LR; Dandekar, AA, The 29th Annual North American Cystic Fibrosis Conference, Pediatric Pulmonology, Phoenix, AZ, 1/8/2015
• Epidemiology and outcomes of Staphylococcus aureus infection in CF.
  Hoffman, LR, The 29th Annual North American Cystic Fibrosis Conference, Pediatric Pulmonology, Phoenix, AZ, 1/8/2015
• Analysis of the microbiota in bronchoalveolar lavage from children with bronchiectasis.
  Marsh, RL; Smith-Vaughan, HC; Kestli, M; Chang, AB; and Hoffman, LR, 15th International Symposium on Microbial Ecology, Seoul, Korea, 1/24/2014
• Sequence - function analysis of clinical LasR variants of Pseudomonas aeruginosa.
  Wolter, DJ; Pope, CE; Dandekar, AA; Hoffman, LR, The 37th European Cystic Fibrosis Conference, Journal of Cystic Fibrosis, Gothenberg, Sweden, 1/12/2014
• Polymicrobial interactions between P. aeruginosa and S. aureus influence biofilm formation.
  Armbruster, CF; Wolter, DJ; Parsek, MR; Hoffman, LR, Biofilm 6, Vienna, Austria, 1/1/2014
• An optimized susceptibility testing method for Staphylococcus aureus small-colony variants.
  Precit, MR; Wolter, DJ; Griffith, A; Burns, JL; and Hoffman, LR, International Conference on Antimicrobial Agents and Chemotherapeutics (ICAAC) International Conference, Washington, DC, 1/1/2014
• Pseudomonas aeruginosa adaptation during chronic CF airway infections impairs bacterial clearance in vivo and dysregulated ICAM-I responses in vitro.
  LaFayette, SL; Houle, D; Radzloch, D; Hoffman, L; Burns, JL; Nguyen, D, 28th Annual North American Cystic Fibrosis Foundation Conference (NACFC), Pediatric Pulmonology, Atlanta, GA, 1/1/2014
• Ivacaftor treatment of patients with the CFTR G551D mutation produces both acute and long term changes in the infecting Pseudomonas aeruginosa populations.
  Hisert, KB; Jorth, P; Cooke, G; Garudathri, J; Wu, X; Pope, C; Grogan, B; Gallagher, CG; Donnelly, SC; Hoffman, L; Bruce, J; Welsh, MJ; McKone, EF; Singh, P, 28th Annual North American Cystic Fibrosis Foundation Conference (NACFC), Pediatric Pulmonology, Atlanta, GA, 1/1/2014
• Studies on the effects of ciprofloxacin on Pseudomonas aeruginosa evolution in cystic fibrosis patients.
  Jorth, P; Hisert, KB; Garudathri, J; Wolter, D; Hoffman, L; Singh, P, 28th Annual North American Cystic Fibrosis Foundation Conference (NACFC), Pediatric Pulmonology, Atlanta, GA, 1/1/2014
• Intestinal Dysbiosis in CF.
  Hoffman, L, 28th Annual North American Cystic Fibrosis Foundation Conference (NACFC), Atlanta, GA, 1/1/2014
• Staphylococcus aureus Small-Colony Variants Are Independently Associated With Worse Lung Disease In A Cohort Of Children With Cystic Fibrosis.
  Hoffman, LR, D. Wolter, PhD, J. Emerson, S. McNamara, A.M. Buccat, X. Qin, E. Cochrane, L. Houston, G. Rogers, P. Marsh, K. Prehar, C. Pope, M. Blackledge, E. Deziel, ..., The 2013 American Thoracic Society Annual Conference, Am J Respir Crit Care Med, Philadelphia, PA, 1/21/2013
• Microarray analysis of the effect of fosfomycin and tobramycin against Pseudomonas aeruginosa from CF patients.
  McCaughey, G; Gilpin, DF; Schneiders, T; Hoffman, LR; McKevitt, M; Elborn, JS; Tunney, M, The 36th European Cystic Fibrosis Conference, Journal of Cystic Fibrosis, Lisbon, Portugal, 1/14/2013
• Staphylococcus aureus Small-Colony Variants Are Independently Associated With Worse Lung Disease Children With Cystic Fibrosis.
  Wolter, D; Emerson, JC; McNamara, S; Buccat, AM; Qin, X.; Cochrane, E; Houston, LS; Rogers, GB; Marsh, P; Prehar, K; Pope, CE; Blackledge, M; Déziel, E; Bruce, KD; Ram..., The 36th European Cystic Fibrosis Conference, Journal of Cystic Fibrosis, Lisbon, Portugal, 1/14/2013
• Three clinically distinct chronic pediatric airway infections share a common core microbiota.
  van der Gast, CJ; Cuthbertson, L; Pope, CE; Marsh, RL; Rogers, GB; Smith-Vaughan, HC; Redding, GJ; Bruce, KD; Chang, AB; Hoffman, LR, The 36th European Cystic Fibrosis Conference, Journal of Cystic Fibrosis, Lisbon, Portugal, 1/13/2013
• Escherichia coli gastrointestinal dysbiosis in young children with cystic fibrosis and nutrient malabsorption.
  Hoffman, LR; Pope, CE; Hayden, HS; Levy, R; Jacobs, MA; Heltshe, SL; McNamara, S; Rohmer, L; Radey, M; Ramsey, BW; Brittnacher, MJ; Borenstein, E; and Miller, SI, The 27th Annual North American Cystic Fibrosis Foundation Conference (NACFC), Pediatric Pulmonology, Salt Lake City, UT, 1/1/2013
• CF lung microbiome: What have we learned?
  Hoffman, LR, The 27th Annual North American Cystic Fibrosis Foundation Conference (NACFC), Pediatric Pulmonology, Salt Lake City, UT, 1/1/2013
• Pseudomonas aeruginosa Phenotypes Distinguish Initial, Intermittent, and Persistent Stages of CF Airway Infection.
  Hoffman, LR; Gibson, RL; Rosenfeld, M; Ramsey, BW; Kulasekara, HD; Retsch-Bogart, GZ; Wolter, DJ; Pope, CE; Houston, LS; Kulasekara, BR; Foster, JM; Khan, U; Burns, JL..., The 27th Annual North American Cystic Fibrosis Foundation Conference (NACFC), Pediatric Pulmonology, Salt Lake City, UT, 1/1/2013
• Join now to see all

Lectures

• Microbiology and Microbiome of Pediatric Bronchiectasis: Post-infectious, CF, and PCD. 
  1/20/2016
• Short-term and long-term effects of ivacaftor treatment on sputum microbiota in CF patients with the G551D CFTR mutation. 
  San Francisco, CA - 1/16/2016
• Pediatric CF GI (Fecal) Microbiomes and Correlation with Clinical Outcomes. 
  1/14/2016
• Modern culture and its discontents: Traditional and molecular microbiology for CF respiratory infections. 
  Malvern, PA - 1/13/2016
• Recent advances in CF microbiology. 
  1/5/2016
• Antibiotic susceptibility testing for Staphylococcus aureus clinical small-colony variants. 
  San Diego, CA - 1/5/2016
• It's the little things: The significance and characterization of Staphylococcus aureus small-colony variants in chronic infections. 
  1/21/2015
• What to expect when you're expectorating: An ecological perspective on the lung in health and disease. 
  1/21/2015
• What to expect when you're expectorating: The microbiota of the pediatric lung in health and disease. 
  University of Washington, Seattle, WA - 1/19/2015
• Molecular approaches to CF Microbiology: Microbiomes from Above and Below 
  Seattle, WA - 1/16/2015
• Short-term and long-term effects of ivacaftor treatment on sputum microbiota in people with the G551D CFTR mutation. 
  Brussels, Belgium - 1/11/2015
• Staphylococcus aureus should not be treated aggressively in infants and children with CF. 
  Phoenix, AZ - 1/10/2015
• Epidemiology and outcomes of Staphylococcus aureus infection in CF. 
  Phoenix, AZ - 1/9/2015
• What to expect when you're expectorating: An ecological perspective on chronic infections in the lung and elsewhere. 
  Darwin, Australia - 1/29/2014
• Considerations for sampling in respiratory microbiota studies: Lessons from cystic fibrosis 
  Royal Children's Hospital, Brisbane, Australia - 1/24/2014
• Airway microbiome in children: Contribution to health and disease 
  San Diego, CA - 1/19/2014
• Lung Phenotype of Juvenile and Adult CFTR-Knockout Ferrets 
  1/10/2014
• Intestinal Dysbiosis in CF. 
  Atlanta, GA - 1/9/2014
• CF lung microbiome. 
  Salt Lake City, UT - 1/25/2013
• CF lung microbiome: What have we learned? 
  Salt Lake City, UT - 1/24/2013
• Staphylococcus aureus Small-Colony Variants Are Independently Associated With Worse Lung Disease In A Cohort Of Children With Cystic Fibrosis. 
  Philadelphia, PA - 1/21/2013
• The prevalence and clinical significance of Staphylococcus aureus small-colony variants in chronic CF lung infections. 
  1/19/2013
• Potential interaction between inhaled tobramycin and azithromycin. 
  1/18/2013
• Staphylococcus aureus Small-Colony Variants Are Independently Associated With Worse Lung Disease Children With Cystic Fibrosis. 
  Lisbon, Portugal - 1/14/2013
• Three clinically distinct pediatric airway infections share a common core microbiota. 
  Lisbon, Portugal - 1/13/2013
• Join now to see all

Other

• The Low pH-induced Conformational Change in the Influenza Hemagglutinin: Inhibitor Design 
  Hoffman, LR, PhD thesis, UCSF
  1/1/1996
• How aspirin works 
  Hoffman, LR, How Stuff Works
  http://health.howstuffworks.com/aspirin.htm