LukeMilburnJudgeMDPhD

PubMed

• 16 citations
  Bioengineered optogenetic model of human neuromuscular junction.
  Olaia F. Vila, Miguel Chavez, Stephen P. Ma, Keith Yeager, Lyandysha V. Zholudeva, Jennifer M. Colón-Mercado, Yihuai Qu, Trevor R. Nash, Carmen Lai, Carissa M. Felicia...> ;Biomaterials. 2021 Sep 1
• 9 citations
  Allele-Specific Gene Editing Rescues Pathology in a Human Model of Charcot-Marie-Tooth Disease Type 2E.
  Carissa M. Feliciano, Kenneth Wu, Hannah L Watry, Chiara B.E. Marley, Gokul N. Ramadoss, Hana Y. Ghanim, Angela Z. Liu, Lyandysha V. Zholudeva, Todd C. McDevitt, Mario...> ;Frontiers in Cell and Developmental Biology. 2021 Aug 16
• 8 citations
  Rapid, precise quantification of large DNA excisions and inversions by ddPCR.
  Hannah L. Watry, Carissa M. Feliciano, Ketrin Gjoni, Gou Takahashi, Yuichiro Miyaoka, Bruce R. Conklin, Luke M. Judge> ;Scientific Reports. 2020 Sep 10
• 98 citations
  Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes
  Michael Song, Xiaoyu Yang, Xingjie Ren, Lenka Maliskova, Bingkun Li, Ian R. Jones, Chao Wang, Fadi Jacob, Kenneth Wu, Michela Traglia, Tse Wai Tam, Kirsty Jamieson, Si...> ;Nature Genetics. 2019 Jul 31
• 225 citations
  Unbiased detection of CRISPR off-targets in vivo using DISCOVER-Seq.
  Beeke Wienert, Stacia K. Wyman, Christopher D. Richardson, Charles D. Yeh, Pinar Akcakaya, Michelle J. Porritt, Michaela Morlock, Jonathan T. Vu, Katelynn R. Kazane, H...> ;Science. 2019 Apr 19
• 8 citations
  Two patients with FOXF1 mutations with alveolar capillary dysplasia with misalignment of pulmonary veins and other malformations: Two different presentations and outcomes
  Aya Abu-El-Haija, Jeffrey R. Fineman, Andrew J. Connolly, Priyanka Murali, Luke M. Judge, Anne Slavotinek> ;American Journal of Medical Genetics. Part A. 2018 Dec 1
• 12 citations
  Erratum: Variable rescue of microtubule and physiological phenotypes in mdx muscle expressing different miniaturized dystrophins (Human Molecular Genetics (2018) 27:12...
  D'anna M. Nelson, Angus Lindsay, Luke M. Judge, Dongsheng Duan, Jeffrey S. Chamberlain, Dawn A. Lowe, James M. Ervasti> ;Human Molecular Genetics. 2018 Aug 1
• Variable rescue of microtubule and physiological phenotypes in mdx muscle expressing different miniaturized dystrophins.
  Nelson, D. M.,Lindsay, A.,Judge, L. M.,Duan, D.,Chamberlain, J. S.,Lowe, D. A.,Ervasti, J. M.> ;Hum. Mol. Genet.. 2018 Apr 05
• 64 citations
  A BAG3 chaperone complex maintains cardiomyocyte function during proteotoxic stress
  Luke M. Judge, Juan A. Perez-Bermejo, Annie Truong, Alexandre J.S. Ribeiro, Jennie C. Yoo, Christina L Jensen, Mohammad A. Mandegar, Nathaniel Huebsch, Robyn M. Kaake,...> ;JCI Insight. 2017 Jul 20
• 151 citations
  Miniaturized iPS-Cell-Derived Cardiac Muscles for Physiologically Relevant Drug Response Analyses.
  Nathaniel Huebsch, Peter Loskill, Nikhil Deveshwar, C. Ian Spencer, Luke M. Judge, Mohammad A. Mandegar, Cade B. Fox, Tamer M.A. Mohamed, Zhen Ma, Anurag Mathur, Alice...> ;Scientific Reports. 2016 Apr 20
• 315 citations
  CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs
  Mohammad A. Mandegar, Nathaniel Huebsch, Ekaterina B. Frolov, Edward Shin, Annie Truong, Michael P. Olvera, Amanda H. Chan, Yuichiro Miyaoka, Kristin Holmes, C. Ian Sp...> ;Cell Stem Cell. 2016 Apr 7
• 179 citations
  Automated Video-Based Analysis of Contractility and Calcium Flux in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Cultured over Different Spatial Scales.
  Nathaniel Huebsch, Peter Loskill, Mohammad A. Mandegar, Natalie C. Marks, Alice S. Sheehan, Zhen Ma, Anurag Mathur, Trieu Nguyen, Jennie C. Yoo, Luke M. Judge, C. Ian ...> ;Tissue Engineering. Part C, Methods. 2015 Jan 12
• 186 citations
  Isolation of single-base genome-edited human iPS cells without antibiotic selection
  Yuichiro Miyaoka, Amanda H. Chan, Luke M. Judge, Jennie Yoo, Miller Huang, Trieu Nguyen, Paweena Lizarraga, Po-Lin So, Bruce R. Conklin> ;Nature Methods. 2014 Mar 1
• 24 citations
  Expression of the dystrophin isoform Dp116 preserves functional muscle mass and extends lifespan without preventing dystrophy in severely dystrophic mice
  Luke M. Judge, Andrea L. Arnett, Glen B. Banks, Jeffrey S. Chamberlain> ;Human Molecular Genetics. 2011 Dec 15
• 73 citations
  Sarcolemmal nNOS anchoring reveals a qualitative difference between dystrophin and utrophin
  Dejia Li, Akshay Bareja, Luke M. Judge, Yongping Yue, Yi Lai, R.J. Fairclough, Kay E. Davies, Jeffrey S. Chamberlain, Dongsheng Duan> ;Journal of Cell Science. 2010 Jun 15
• 64 citations
  The polyproline site in hinge 2 influences the functional capacity of truncated dystrophins
  Glen B. Banks, Luke M. Judge, James M. Allen, Jeffrey S. Chamberlain> ;Plos Genetics. 2010 May 20
• 284 citations
  Dystrophins carrying spectrin-like repeats 16 and 17 anchor nNOS to the sarcolemma and enhance exercise performance in a mouse model of muscular dystrophy
  Yi Lai, Gail D. Thomas, Yongping Yue, Hsiao T. Yang, Dejia Li, Chun Long, Luke M. Judge, Brian Bostick, Jeffrey S. Chamberlain, Ronald L. Terjung, Dongsheng Duan> ;The Journal of Clinical Investigation. 2009 Mar 2
• 86 citations
  Dissecting the signaling and mechanical functions of the dystrophin-glycoprotein complex
  Luke M. Judge, Miki Haraguchiln, Jeffrey S. Chamberlain> ;Journal of Cell Science. 2006 Apr 15
• 12 citations
  Gene therapy for Duchenne muscular dystrophy: AAV leads the way.
  Luke M. Judge, Jeffrey S. Chamberlain> ;Acta Myologica. 2005 Dec 1
• 90 citations
  Discovery and SAR of a novel selective and orally bioavailable nonpeptide classical competitive inhibitor class of protein-tyrosine phosphatase 1B.
  Henrik Sune Andersen, Ole Hvilsted Olsen, Lars Fogh Iversen, Anette L. P. Sørensen, Steen B. Mortensen, Michael S. Christensen, Sven Branner, Thomas Kruse Hansen, Jesp...> ;Journal of Medicinal Chemistry. 2002 Aug 24
• 34 citations
  Protein engineering of protein kinase A catalytic subunits results in the acquisition of novel inhibitor sensitivity.
  Colleen M. Niswender, R. Wesley Ishihara, Luke M. Judge, Chao Zhang, Kevan M. Shokat, G. Stanley McKnight> ;The Journal of Biological Chemistry. 2002 Aug 9
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Journal Articles

• Two Patients with FOXF1 Mutations with Alveolar Capillary Dysplasia with Misalignment of Pulmonary Veins and Other Malformations: Two Different Presentations and Outcomes  
  Luke M Judge, Jeff Fineman, Anne M Slavotinek, American Journal of Medical Genetics Part A