LynnGFeunMD

PubMed

• Racial and ethnic minorities in lower income brackets are associated with late-stage diagnosis of non-ocular melanoma.
  Priyashma Joshi, Ifeanyichukwu Ogobuiro, Alexandra Hernandez, Gabriel De La Cruz Ku, Daniel George Noe, Lynn Feun, Zhao-Jun Liu, Mecker G Möller> ;Cancer Epidemiology. 2023 Dec 1
• ASO Visual Abstract: Omission of Completion Lymph Node Dissection in Sentinel Node Biopsy Positive Head and Neck Cutaneous Melanoma Patients.
  Susan B Kesmodel, Joshua P Kronenfeld, Wei Zhao, Tulay Koru-Sengul, Neha Goel, Daniel N Weingrad, Leonel Hernandez-Aya, Jose Lutzky, Lynn Feun, Mary Garland-Kledzik, J...> ;Annals of Surgical Oncology. 2023 Nov 1
• Omission of Completion Lymph Node Dissection in Sentinel Node Biopsy Positive Head and Neck Cutaneous Melanoma Patients.
  Susan B Kesmodel, Joshua P Kronenfeld, Wei Zhao, Tulay Koru-Sengul, Neha Goel, Daniel N Weingrad, Leonel Hernandez-Aya, Jose Lutzky, Lynn Feun, Mary Garland-Kledzik, J...> ;Annals of Surgical Oncology. 2023 Nov 1
• Cell-Free DNA as a Surveillance Tool for Hepatocellular Carcinoma Patients after Liver Transplant.
  Joao Manzi, Camilla O Hoff, Raphaella Ferreira, Renata Glehn-Ponsirenas, Gennaro Selvaggi, Akin Tekin, Christopher B O'Brien, Lynn Feun, Rodrigo Vianna, Phillipe Abreu> ;Cancers. 2023 Jun 13
• 3 citations
  Dual inhibition of IDO1/TDO2 enhances anti-tumor immunity in platinum-resistant non-small cell lung cancer.
  Chunjing Wu, Sydney A Spector, George Theodoropoulos, Dan J M Nguyen, Emily Y Kim, Ashley Garcia, Niramol Savaraj, Diane C Lim, Ankita Paul, Lynn G Feun, Michael Bicke...> ;Cancer & Metabolism. 2023 May 24
• 5 citations
  Intratumoral oncolytic virus V937 plus ipilimumab in patients with advanced melanoma: the phase 1b MITCI study.
  Brendan D Curti, Jon Richards, John R Hyngstrom, Gregory A Daniels, Mark Faries, Lynn Feun, Kim A Margolin, Sigrun Hallmeyer, Mark Grose, Yiwei Zhang, Anlong Li, Rober...> ;Journal for Immunotherapy of Cancer. 2022 Dec 1
• 17 citations
  A Phase Ib Study of Sotrastaurin, a PKC Inhibitor, and Alpelisib, a PI3Kα Inhibitor, in Patients with Metastatic Uveal Melanoma
  Alexander N. Shoushtari, Shaheer Khan, Kimberly M. Komatsubara, Lynn G. Feun, Nicolas Acquavella, Shahnaz Singh-Kandah, Tiffany Negri, Kelly Abbate, Serge Cremers, Elg...> ;Cancers. 2021 Nov 2
• 2 citations
  An Open–Label, Randomized, Multi–Center Study Comparing the Sequence of High Dose Aldesleukin (Interleukin–2) and Ipilimumab (Yervoy) in Patients with Metastatic Melanoma
  Merve Hasanov, Denái R. Milton, William H. Sharfman, Bret Taback, Lee D. Cranmer, Gregory A. Daniels, Lawrence E. Flaherty, Sigrun Hallmeyer, Mohammed M. Milhem, Lynn ...> ;Oncoimmunology. 2021 Oct 9
• 5 citations
  Enhancing the Effect of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Signaling and Arginine Deprivation in Melanoma
  Chunjing Wu, Min You, Dao M. Nguyen, Medhi Wangpaichitr, Ying-Ying Li, Lynn G. Feun, Macus Tien Kuo, Niramol Savaraj> ;International Journal of Molecular Sciences. 2021 Jul 16
• 13 citations
  Cisplatin Resistance and Redox-Metabolic Vulnerability: A Second Alteration.
  Medhi Wangpaichitr, George Theodoropoulos, Dan J.M. Nguyen, Chunjing Wu, Sydney A. Spector, Lynn G. Feun, Niramol Savaraj> ;International Journal of Molecular Sciences. 2021 Jul 9
• 22 citations
  Targeting the Proline-Glutamine-Asparagine-Arginine Metabolic Axis in Amino Acid Starvation Cancer Therapy.
  Macus Tien Kuo, Helen H.W. Chen, Lynn G. Feun, Niramol Savaraj> ;Pharmaceuticals. 2021 Jan 18
• 21 citations
  Prolonged Complete Response With Combined Dabrafenib and Trametinib After BRAF Inhibitor Failure in BRAF-Mutant Glioblastoma
  Marina Kushnirsky, Lynn G. Feun, Sakir H. Gultekin, Macarena I. de la Fuente> ;JCO Precision Oncology. 2020 Feb 3
• 12 citations
  Collaboration Between RSK-EphA2 and Gas6-Axl RTK Signaling in Arginine Starvation Response That Confers Resistance to EGFR Inhibitors
  Macus Tien Kuo, Yan Long, Wen Bin Tsai, Ying-Ying Li, Helen H.W. Chen, Lynn G. Feun, Niramol Savaraj> ;Translational Oncology. 2020 Feb 1
• 1 citations
  Unilateral Fourth Nerve Palsy due to Presumed Metastatic Melanoma.
  Joshua Pasol, Eric A. Mellon, Lynn G. Feun, Gaurav Saigal, Tejan Diwanji, Ricardo J. Komotar> ;Journal of Neuro-Ophthalmology. 2021 Mar 1
• 223 citations
  Single-cell analysis reveals new evolutionary complexity in uveal melanoma.
  Michael A. Durante, Daniel A. Rodriguez, Stefan Kurtenbach, Jeffim N. Kuznetsov, Margaret I. Sanchez, Christina L. Decatur, Helen Snyder, Lynn G. Feun, Alan S. Livings...> ;Nature Communications. 2020 Jan 24
• 29 citations
  Targeting the Kynurenine Pathway for the Treatment of Cisplatin-Resistant Lung Cancer
  Dan J.M. Nguyen, George Theodoropoulos, Ying-Ying Li, Chunjing Wu, Wei Sha, Lynn G. Feun, Theodore J. Lampidis, Niramol Savaraj, Medhi Wangpaichitr> ;Molecular Cancer Research. 2020 Jan 1
• 94 citations
  First-in-Human Phase I Study of Fisogatinib (BLU-554) Validates Aberrant FGF19 Signaling as a Driver Event in Hepatocellular Carcinoma.
  Richard D. Kim, Debashis Sarker, Tim Meyer, Thomas Yau, Teresa Macarulla, Joong-Won Park, Su Pin Choo, Antoine Hollebecque, Max Sung, Ho Yeong Lim, Vincenzo Mazzaferro...> ;Cancer Discovery. 2019 Dec 1
• 115 citations
  Phase 2 study of pembrolizumab and circulating biomarkers to predict anticancer response in advanced, unresectable hepatocellular carcinoma
  Lynn G. Feun, Ying-Ying Li, Chunjing Wu, Medhi Wangpaichitr, Patricia D. Jones, Stephen P. Richman, Beatrice L. Madrazo, Deukwoo Kwon, Monica T. Garcia-Buitrago, Paul ...> ;Cancer. 2019 Oct 15
• 36 citations
  Optical coherence tomography imaging of melanoma skin cancer
  Ali Rajabi-Estarabadi, Julie M. Bittar, Caiwei Zheng, Vanessa Nascimento, Isabella Camacho, Lynn G. Feun, Mohammadreza Nasiriavanaki, Michael Kunz, Keyvan Nouri> ;Lasers in Medical Science. 2019 Mar 1
• 10 citations
  Phase II trial of SOM230 (pasireotide LAR) in patients with unresectable hepatocellular carcinoma
  Lynn G. Feun, Medhi Wangpaichitr, Ying-Ying Li, Deukwoo Kwon, Stephen P. Richman, Peter J. Hosein, Niramol Savaraj> ;Journal of Hepatocellular Carcinoma. 2018 Jan 12
• 17 citations
  Degradation of AMPK-α1 sensitizes BRAF inhibitor-resistant melanoma cells to arginine deprivation.
  Ying-Ying Li, Chunjing Wu, Sumedh S. Shah, Shu Mei Chen, Medhi Wangpaichitr, Macus Tien Kuo, Lynn G. Feun, Xiaoqing Han, Miguel Suarez, Jeffrey S. Prince, Niramol Savaraj> ;Molecular Oncology. 2017 Dec 1
• 18 citations
  Chromatin remodeling system p300-HDAC2-Sin3A is involved in Arginine Starvation-Induced HIF-1α Degradation at the ASS1 promoter for ASS1 Derepression
  Wen Bin Tsai, Yan Long, Jeffrey T. Chang, Niramol Savaraj, Lynn G. Feun, Manfred Jung, Helen H.W. Chen, Macus Tien Kuo> ;Scientific Reports. 2017 Sep 7
• 24 citations
  Autophagic mechanism in anti-cancer immunity: Its pros and cons for cancer therapy
  Ying-Ying Li, Lynn G. Feun, Angkana Thongkum, Chiao Hui Tu, Shu Mei Chen, Medhi Wangpaichitr, Chunjing Wu, Macus Tien Kuo, Niramol Savaraj> ;International Journal of Molecular Sciences. 2017 Jun 19
• 65 citations
  Exploiting ROS and metabolic differences to kill cisplatin resistant lung cancer
  Medhi Wangpaichitr, Chunjing Wu, Ying-Ying Li, Dan J.M. Nguyen, Hande Kandemir, Sumedh S. Shah, Shu Mei Chen, Lynn G. Feun, Jeffrey S. Prince, Macus Tien Kuo, Niramol ...> ;Oncotarget. 2017 May 2
• 32 citations
  Relationship of Metabolic Alterations and PD-L1 Expression in Cisplatin Resistant Lung Cancer.
  Medhi Wangpaichitr, Hande Kandemir, Ying-Ying Li, Chunjing Wu, Djm Nguyen, Lynn G. Feun, Marcus T. Kuo, Niramol Savaraj> ;Cell & Developmental Biology. 2017 Apr 28
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Lectures

• Plasma biomarkers to predict pembrolizumab response in HCC patients. 
  ASCO Annual Meeting 2019 - Chicago, IL - 5/31/2019
• Phase II study of pembrolizumab in advanced, unresectable hepatocellular carcinoma. 
  2018 ASCO Annual Meeting - Chicago, Illinois - 06/3/2018