MaciejSLesniakMD

PubMed

• Lactate dehydrogenase A regulates tumor-macrophage symbiosis to promote glioblastoma progression.
  Fatima Khan, Yiyun Lin, Heba Ali, Lizhi Pang, Madeline Dunterman, Wen-Hao Hsu, Katie Frenis, R Grant Rowe, Derek A Wainwright, Kathleen McCortney, Leah K Billingham, J...> ;Nature Communications. 2024 Mar 5
• Cancer-associated fibroblast-secreted collagen is associated with immune inhibitor receptor LAIR1 in gliomas.
  Shashwat Tripathi, Hinda Najem, Corey Dussold, Sebastian Pacheco, Jason Miska, Kathleen McCortney, Alicia Steffens, Jordain Walshon, Daniel Winkowski, Michael Cloney, ...> ;The Journal of Clinical Investigation. 2024 Feb 15
• GlioPredictor: a deep learning model for identification of high-risk adult IDH-mutant glioma towards adjuvant treatment planning.
  Sita, T., Teo, P., Wu, Y., Zheng, S., Rammohan, N., Lesniak, M., Sachdev, S., Thomas, T.> ;Scientific Reports. 2024 Jan 25
• Metixene is an incomplete autophagy inducer in preclinical models of metastatic cancer and brain metastases.
  Fares, J., Jawad Fares, Edgar Petrosyan, Deepak Kanojia, Crismita Dmello, Alex Cordero, Joseph T Duffy, Ragini Yeeravalli, Mayurbhai H Sahani, Peng Zhang, Aida Rashidi...> ;The Journal of Clinical Investigation. 2023 Dec 15
• 4 citations
  Myeloid cell-derived creatine in the hypoxic niche promotes glioblastoma growth.
  Aida Rashidi, Leah K Billingham, Andrew Zolp, Tzu-Yi Chia, Caylee Silvers, Joshua L Katz, Cheol H Park, Suzi Delay, Lauren Boland, Yuheng Geng, Steven M Markwell, Cris...> ;Cell Metabolism. 2024 Jan 2
• 2 citations
  LDHA-regulated tumor-macrophage symbiosis promotes glioblastoma progression.
  Fatima Khan, Yiyu Lin, Heba Ali, Lizhi Pang, Madeline Dunterman, Wen-Hao Hsu, Katie Frenis, R Grant Rowe, Derek Wainwright, Kathleen McCortney, Leah Billingham, Jason ...> ;Research Square. 2023 Oct 5
• 3 citations
  Cellular senescence in glioma.
  Rafał Chojak, Jawad Fares, Maciej S Lesniak, Edgar Petrosyan> ;Journal of Neuro-Oncology. 2023 Aug 1
• 2 citations
  Biological principles of adult degenerative scoliosis.
  Jawad Fares, Maciej S Lesniak, Tyler R Koski, Najib E El Tecle, Edgar Petrosyan> ;Trends in Molecular Medicine. 2023 Sep 1
• 27 citations
  Repeated blood-brain barrier opening with an implantable ultrasound device for delivery of albumin-bound paclitaxel in patients with recurrent glioblastoma: a phase 1 ...
  Adam M Sonabend, Andrew Gould, Christina Amidei, Rachel Ward, Karyn A Schmidt, Daniel Y Zhang, Cristal Gomez, John F Bebawy, Benjamin P Liu, Guillaume Bouchoux, Carole...> ;The Lancet. Oncology. 2023 May 1
• 33 citations
  STING agonist-loaded, CD47/PD-L1-targeting nanoparticles potentiate antitumor immunity and radiotherapy for glioblastoma.
  Peng Zhang, Aida Rashidi, Junfei Zhao, Caylee Silvers, Hanxiang Wang, Brandyn Castro, Abby Ellingwood, Yu Han, Aurora Lopez-Rosas, Markella Zannikou, Crismita Dmello, ...> ;Nature Communications. 2023 Mar 23
• 5 citations
  Checkpoint kinase 1/2 inhibition potentiates anti-tumoral immune response and sensitizes gliomas to immune checkpoint blockade.
  Crismita Dmello, Junfei Zhao, Li Chen, Andrew Gould, Brandyn Castro, Victor A Arrieta, Daniel Y Zhang, Kwang-Soo Kim, Deepak Kanojia, Peng Zhang, Jason Miska, Ragini Y...> ;Nature Communications. 2023 Mar 22
• 12 citations
  IL15 modification enables CAR T cells to act as a dual targeting agent against tumor cells and myeloid-derived suppressor cells in GBM.
  Markella Zannikou, Joseph T Duffy, Rebecca N Levine, Maggie Seblani, Qianli Liu, Aaron Presser, Victor A Arrieta, Christopher J Chen, Adam M Sonabend, Craig M Horbinsk...> ;Journal for Immunotherapy of Cancer. 2023 Feb 1
• 8 citations
  Next-generation antigen-presenting cell immune therapeutics for gliomas.
  Catalina Lee-Chang, Maciej S Lesniak> ;The Journal of Clinical Investigation. 2023 Feb 1
• 3 citations
  Endoplasmic Reticulum Stress in the Brain Tumor Immune Microenvironment.
  Luis G Fernandez, Ragini Yeeravalli, Crismita Dmello, Joseph T Duffy, Peng Zhang, Catalina Lee-Chang, Jason Miska, Atique U Ahmed, Adam M Sonabend, Irina V Balyasnikov...> ;Molecular Cancer Research. 2023 May 1
• 1 citations
  B-cells Drive Response to PD-1 Blockade in Glioblastoma Upon Neutralization of TGFβ-mediated Immunosuppression.
  David Hou, Brandyn Castro, Mark Dapash, Andrew Zolp, Joshua Katz, Víctor Arrieta, Jana Biermann, Johannes Melms, Jan Kueckelhaus, Jasim Benotmane, Mark Youngblood, Aid...> ;Research Square. 2023 Jan 9
• Challenging Cases in Neuro-Oncology.
  Rimas V Lukas, Maciej M Mrugala, Maciej S Lesniak, James P Chandler> ;Seminars in Neurology. 2022 Dec 1
• 5 citations
  Neurological applications of belzutifan in von Hippel-Lindau disease.
  Yue Zhang, Catherine C Nguyen, Nigel T Zhang, Nicolas S Fink, Jordan D John, Omkar G Venkatesh, Jonathan D Roe, Steven C Hoffman, Maciej S Lesniak, Jean-Paul Wolinsky,...> ;Neuro-Oncology. 2023 May 4
• 2 citations
  Optimizing the patient handoff and progress note documentation efficiency in the EPIC EMR system within a neurosurgery residency: A quality improvement initiative.
  Mykhaylo D Krushelnytskyy, Mark W Youngblood, Maciej S Lesniak, Hanna R Kemeny, Luis G Fernandez, Kirsten L Bell Burdett, Hui Zhang, Tord D Alden, Nader S Dahdaleh> ;Journal of Clinical Neuroscience. 2022 Nov 1
• 8 citations
  Repurposing autophagy regulators in brain tumors.
  Alex Cordero, Aida Rashidi, Víctor A Arrieta, Deepak Kanojia, Maciej S Lesniak, Edgar Petrosyan, Jawad Fares> ;International Journal of Cancer. 2022 Jul 15
• 2 citations
  Mean Brain Dose Remains Uninfluenced by the Lesion Number for Gamma Knife Stereotactic Radiosurgery for 10+ Metastases.
  Timothy L Sita, Mahesh Gopalakrishnan, Michael K Rooney, Alexander Ho, Rohan Savoor, Adam M Sonabend, Matthew C Tate, James P Chandler, Maciej S Lesniak, Tim J Kruser,...> ;World Neurosurgery. 2022 Sep 1
• 30 citations
  Circadian Regulator CLOCK Drives Immunosuppression in Glioblastoma.
  Wenjing Xuan, Wen-Hao Hsu, Fatima Khan, Madeline Dunterman, Lizhi Pang, Derek A Wainwright, Atique U Ahmed, Amy B Heimberger, Maciej S Lesniak, Peiwen Chen> ;Cancer Immunology Research. 2022 Jun 3
• 3 citations
  Translocon-associated Protein Subunit SSR3 Determines and Predicts Susceptibility to Paclitaxel in Breast Cancer and Glioblastoma.
  Crismita Dmello, Aarón Sonabend, Victor A Arrieta, Daniel Y Zhang, Deepak Kanojia, Li Chen, Andrew Gould, Jiangshan Zhang, Seong Jae Kang, Jan Winter, Craig Horbinski,...> ;Clinical Cancer Research. 2022 Jul 15
• 7 citations
  Central nervous system immune interactome is a function of cancer lineage, tumor microenvironment, and STAT3 expression.
  Hinda Najem, Martina Ott, Cynthia Kassab, Arvind Rao, Ganesh Rao, Anantha Marisetty, Adam M Sonabend, Craig Horbinski, Roel Verhaak, Anand Shankar, Santhoshi N Krishna...> ;JCI Insight. 2022 May 9
• 10 citations
  Leptomeningeal metastases: the future is now.
  Rimas V Lukas, Jigisha P Thakkar, Massimo Cristofanilli, Sunandana Chandra, Jeffrey A Sosman, Jyoti D Patel, Priya Kumthekar, Roger Stupp, Maciej S Lesniak> ;Journal of Neuro-Oncology. 2022 Feb 1
• 7 citations
  Combination of tucatinib and neural stem cells secreting anti-HER2 antibody prolongs survival of mice with metastatic brain cancer.
  Alex Cordero, Matthew D Ramsey, Deepak Kanojia, Jawad Fares, Charles W Schwartz, Rachel Burga, Peng Zhang, Aida Rashidi, Brandyn Castro, Ting Xiao, Catalina Lee-Chang,...> ;Proceedings of the National Academy of Sciences of the United States of America. 2022 Jan 4
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Journal Articles

• Tamoxifen Overrides Autophagy Inhibition in Beclin-1-Deficient Glioma Cells and Their Resistance to Adenovirus-Mediated Oncolysis via Upregulation of PUMA and BAX  
  Maciej Lesniak, MD, Nature
• Hitting a moving target: glioma stem cells demand new approaches in glioblastoma therapy  
  Spencer DA, Auffinger BM, Murphy JP, Muroski ME, Qiao J, Gorind Y, Lesniak MS, Current Cancer Drug Targets, 1/15/2016
• Dynamic in vivo SPECT imaging of neural stem cells functionalized with radiolabeled nanoparticles for tracking of glioblastoma  
  Cheng SH, Yu D, Tsai HM, Morshed RA, Kanojia DA, Lo LW, Govind Y, Zhang L, Aboody KS, Lesniak MS, Chen CT, and Balyasnikova IV, J Nuc Med, 1/1/2016
• Controlled payload release by magnetic field triggered neural stem cell destruction for malignant glioma treatment  
  Muroski M, Morshed RA, Cheng Y, Vemulkar R, Petit DC, Mansell R, Han Y, Zhang L, Cownburn RP, and Lesniak MS, PLoS One, 1/1/2016
• Characterization and functional analysis of scFV-based CARs to redirect T cells to IL13Ralpha2 positive glioma  
  Krenciute G, Krebs S, Torres D, Wu J, Liu H, Dotti G, Lesniak MS, Balyasnikova IV, and Gottschalk S, Molecular Therapy, 1/1/2016
• Viral vector production: adenovirus  
  Kim JW, Morshed RA, Kane RA, Auffinger B, Qioa J, and Lesniak MS, Methods Mol Biol, 1/1/2016
• Cell-penetrating peptide-modified gold nanoparticles for the delivery of doxorubicin to brain metastatic breast cancer  
  Morshed RA, Muroski ME, Dai Q, Wegsheid ML, Auffinger B, Yu D, Han Y, Zhang L, Wu M, Cheng Y, and Lesniak MS, Mol Pharm, 1/1/2016
• GLP toxicity and biodistribution study of a conditionally replicative adenoviral vector, CRAd-S-pk7, administered by intracerebral injection to Syrian hamsters  
  Kim WJ, Auffinger B, Hebert CD, Spencer DA, Miska J, Chang AL, Kane JR, Kanojia D, Qiao J, Mann JF, Ahmed AU, and Lesniak MS, J Transl Medicine, 1/1/2016
• Hypoxic-preconditioned bone marrow stem cell media significantly improves outcome after retinal ischemia in rats  
  Roth S, Dreixler J, Mathew B, Balyasnikova IV, Mann JR, Baddapoti V, Xue L, and Lesniak MS, Investigative Opthalmology and Visual Science, 1/1/2016
• CCL2 produced by glioma microenvironment is essential for the recruitment of regulatory T cells and myeloid derived suppressor cells  
  Chang AL, Miska J, Wainwright DA, Dey M, Yu D, Kaonjia D, Pituch KC, Qiao J, Pytel P, Han Y, Wu M, Zhang L, Ahmed AU, and Lesniak MS, Cancer Research, 1/1/2016
• Neurological management of Von-Hippel-Lindau Disease  
  Hodgson TS, Nielsen SM, Lesniak MS, and Lukas RV, Neurologist, 1/1/2016
• Intranasal oncolytic virotherapy with CXCR-4 enahnced stem cells extends survival in mouse model of glioma  
  Dey M, Dou Y, Kanojia D, Li G, Sukhanova M, Spencer D, Zhang L, Han Y, Ahmed AU, Aboody KS, Lesniak MS, and Balyasnikova IV, Stem Cell Reports, 1/1/2016
• De-differentiation of glioma cells to glioma stem-like cells by therapeutic stress-induced HIF signaling in the recurrent GBM model  
  Lee G, Auffinger B, Guo D, Hasan T, Deheeger M, Tobias AL, Kim JY, Atashi F, Zhang L, Lesniak MS, and Ahmed AU, Mol Cancer Ther, 1/1/2016
• Neurological management of von Hippel-Lindau disease  
  Neurological management of von Hippel-Lindau disease, Neurologist, 1/1/2016
• Cytomegalovirus and glioma: putting the cart before the horse  
  Dey M, Ahmed AU, and Lesniak MS, J Neurology Neurosurgery and Psychiatry, 1/1/2015
• Analysis of glioblastoma tumor coverage by oncolytic virus-loaded neural stem cells using MRI-based tracking and histological reconstruction  
  Morshed RA, Gutova M, Juliano J, Barish ME, Hawkind-Daarud A. Oganesyan D, Vasgen K, Yang T, Annala A, Ahmed AU, Aboody KS, Swanson KR, Moats RA, and Lesniak MS, Cancer Gene Therapy, 1/1/2015
• The role of IDO in brain tumor immunotherapy  
  Zhai L, Lauing KL, Chang AL, Dey M, Qian J, Cheng Y, Lesniak MS, and Wainwright DA, J Neurooncology, 1/1/2015
• Intratumoral oncolytic adenoviral treatment modulates the glioma microenvironment and facilitates systemic tumor-antigen specific T cell therapy  
  Qiao J, Dey M, Chang AL, Kim JW, Miska J, Ling A, Nettlebeck D, Han Y, Zhang L, Lesniak MS, Oncoimmunology, 1/1/2015
• Society for Neuro-Oncology 2014 Annual Meeting Updates on Central Nervous System Metastases  
  Lukas RV, Mehta M, Lin N, and Lesniak MS, Neuro-Oncology: Clinical Practice, 1/1/2015
• bIII-tubulin regulates breast cancer metastases to the brain  
  Kanojia D, Morshed RA, Zhang L, Miska JM, Qiao J, Kim JW, Pytel P, Balyasnikova IV, Lesniak MS and Ahmed AU, Mol Cancer Ther, 1/1/2015
• Intranasal delivery of therapeutic neural stem cells to target intracerebral glioma using CE/CPT-11 enzyme/prodrug therapy  
  Gutova M, Shahmanyan D, Oganesyan D, Abramyants Y, Li Z, Annala AJ, Metz MZ, Gichrist M, Tirughana R, Danielyan L, Frey WH, D’Apuzzo M, Khankaldyyan V, Ghoda LY, Najba..., Journal of Stem Cell Research and Regenerative Medicine, 1/1/2015
• Unlocking the promise of oncoytic virotherapy in glioma: combination with chemotherapy to enhance efficacy  
  Spencer DA, Young JS, Kanojia D, Kim JW, Polster SP, Murphy JP, and Lesniak MS, Therapeutic Delivery, 1/1/2015
• Dendritic cell based vaccines that utilize myeloid rather than plasmacytoid cells offer a superior survival advantage in malignant glioma  
  Dey M, Chang AL, Wainwright DA, Ahmed AU, Balyasnikova IV, Pyter P, Han Y, Tobias A, Zhang L, Qiao J, and Lesniak MS, J Immunology, 1/1/2015
• A genetically modified adenoviral vector with a phage display derived peptide incorporated into fiber fibritin chimera prolongs survival in experimental glioma  
  Kim JW, Kane RJ, Young YS, Chang AL, Kanojia D, Morshed D, Miska J, Ahmed AU, Balyasnikova IV, Han Y, Zhang L, Curiel D, and Lesniak MS, Human Gene Therapy, 1/1/2015
• Highly tunable perpendicularly magnetized synthetic antiferromagents for biotechnology applications  
  Vemulkar R, Mansell R, Petit D, Lesniak MS, and Cowburn R, Applied Physics Letters, 1/1/2015
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Books/Book Chapters

• Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics 
  Chapter: Gene/viral treatment approaches for malignant brain cancer 
  Kim JW, Pituch KC, Xiao A, Young YS, Panek WK, Muroski ME, Rashidi A, Kane RB, Kanojia D, Lesniak MSEditors: Newton H.Elsevier, Waltham, MAEdition 2nd,2017
• Mesenchymal Stromal Cells as Tumor Stromal Modulators 
  Chapter: All Aboard: Mesenchymal Stem Cells as Carriers for Virotherapy 
  Kim JW, Murphy J, Chang AL, Spencer DA, Kane R, Kanojia D, Rashidi A, Young JS, and Lesniak MSEditors: Garcia MG, and Bolontrade MF.Elsevier, Waltham, MA2016
• Translational Immunotherapy of Brain Tumors 
  Chapter: The Role of Regulatory T Cells and Indoleamine 2,3-Dioxygenase in Brain Tumor Immunosuppression 
  Dey M, Chang AL, Miska J, Qiao J, and Lesniak MSEditors: Sampson JH.Elsevier, Waltham, MA2016
• Noble Metal Nanoparticles for Biomedical Applications 
  Chapter: Gold nanoparticles for the treatment of gliomas 
  Page 151 - 176Murphy J, Spencer D, Cheng Y, and Lesniak MSEditors: Shi D.World Scientific Publishing Company, Singapore2015
• Neurosurgical Infectious Disease: Surgical and Nonsurgical Management 
  Chapter: Immunology of the CNS 
  Page 3 - 15Nigam P, and Lesniak MSEditors: Hall WA and Kim PD.Thieme Publishers, New York, NY2014
• Controversies in Neuro-Oncology: Best Evidence Medicine for Brain Tumor Surgery 
  Chapter: The role of local drug delivery in management of newly diagnosed and recurrent high grade gliomas 
  Page 76 - 90Dey M, Brem H, and Lesniak MSEditors: Quinones-Hinojosa A and Raza SM.Thieme Publishers, New York, NY2013
• Glioma: Immunotherapeutic Approaches 
  Chapter: Mechanisms of Immune Evasion By Gliomas 
  Rolle CE, Sengupta S, Lesniak MSEditors: Yamanaka, R.2012
• Glioblastoma: Risk factors, diagnosis, and treatment options 
  Page 1 - 42Moon KS, and Lesniak MSEditors: Pintuck S and Reynold C.Nova Science Publishers, Inc, Hauppauge, NY2012
• Methods of Cancer Diagnosis, Therapy, and Prognosis: Brain Cancer 
  Chapter: Intracranial Glioma: Delivery of an Oncolytic Adenovirus 
  Kranzler J, Tyler MA, Ulasov IV, and Lesniak MSEditors: Hayat, MA.Springer-Verlag, Berlin, Germany2011
• Oncolytic Viruses: Methods and Protocols, Methods in Molecular Biology 
  Chapter: Maintaining and Loading Neural Stem Cells for Delivery of an Oncolytic Adenovirus to Brain Tumors 
  Ahmed A, Ulasov IV, Mercer RW and Lesniak MSEditors: Kirn, D and Thorne, S.Springer Science, New York, NY2011
• Tumors of the Central Nervous System 
  Chapter: Malignant Glioma: Chemovirotherapy 
  Ferguson SD, LaRiviere MJ, Mansour N, and Lesniak MSEditors: Hayat, MA.Springer-Verlag, Berlin, Germany2011
• Cancer Stem Cells 
  Chapter: Therapeutic Strategies Targeting Cancer Stem Cells 
  Page 375 - 388Ahmed A, Thaci B, Wainwright D, Dey M, and Lesniak MSEditors: Shostak S.InTech Publishing2011
• Pharmaceutical Perspectives of Cancer Therapeutics 
  Chapter: Targeted Therapies for Malignant Brain Tumors 
  Page 475 - 519Tyler MA, Sugihara A, Ulasov IV, and Lesniak MSEditors: Ram, M.AAPS-Springer, Inc., Berlin, Germany2009
• New Gene Therapy and Cancer Research 
  Chapter: Gene and Viral Oncolytic Therapies for Malignant Glioma 
  Page 205 - 226Sonabend AM, Ulasov IV, Dana K, and Lesniak MSNova Science Publishers, Inc., Hauppauge, NY2008
• High-Grade Gliomas: Diagnosis and Treatment 
  Chapter: Gene Therapy for Malignant Gliomas 
  Page 419 - 430Lesniak MS, and Olivi AEditors: Barnett GH.Humana Press, Totowe, NJ2006
• Brain Cancer Therapy and Surgical Interventions 
  Chapter: Overcoming the Barriers of the Central Nervous System: Novel Methods of Drug Delivery to Brain Cancer 
  Page 1 - 21Schmitt AM, Lesniak MSNova Science Publishers, Inc., Hauppauge, NY2006
• Brain Tumors-Advances in Biology, Diagnosis, and Therapy 
  Chapter: Targeting Drugs to Tumors of the Central Nervous System 
  Page 343 - 358Lesniak MS, Frazier J, Brem HEditors: Ali-Osman F.Humana Press, Totowe, NJ2004
• Intracranial Metastasis: Current Management Strategies 
  Chapter: Brain Metastasis from Gynecologic Cancers 
  Page 331 - 351Lesniak MS, and Olivi AEditors: Sawaya R.Blackwell Futura Publishing Co, Malden, MA2004
• Current Management in Child Neurology 
  Chapter: Pediatric Intracranial Aneurysms 
  Page 519 - 524Lesniak MS, and Tamargo RJEditors: Maria BL.B.C.Decker Publishing Co, Hamilton, Ontario, CanadaEdition 2nd,2002
• The in vitro B cell response to polysaccharide antigens in the Wiskott-Aldrich Syndrome 
  Lesniak MSHarvard University Press, Cambridge, MA1992
• Therapeutic Ribonucleic Acids in Brain Tumors 
  Chapter: Gene Therapy For Malignant Glioma 
  Page 103 - 124Sonabend AM, Ulasov IV, and Lesniak MSEditors: Erdmann, VA, Reifenberger G, and Barciszewski, J.Springer-Verlag, Berlin, Germany
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Abstracts/Posters

• Gross-total resection and adjuvant radiation most significant predicators of improved survival in atypical meningioma
  Rydzewski NR, Lesniak MS, Chandler JP, Tate MC, Sachdev S, American Society for Radiation Oncology 58th Annuyal Meeting, San Diego, CA, 1/27/2017
• Clinical and molecular differences between African-American and Caucasian glioma patients
  Wu M, Horbinski C, Chang AL, Ahmed AU, Balyasnikova IV, Chandler JP, and Lesniak MS, The Fifteenth Asia Pacific Bioinformatics Conference, Shenzhen, China, 1/18/2017
• Intranasal delivery of mesenchymal stem cells targets diffuse intrinsic pontine glioma in mouse model
  Chastofsky M, Procissi D, Yang C, Goldman S, Lesniak MS, Hashizume R, and Balyasnikova IV, World Federation of Neuro-Oncology Meeting, Zurich, Switzerland, 1/7/2017
• Comparing tumor cell subpopulation changes during intracranial GBM PDX regrowth following radiation only vs. temozolomide only vs. combination therapy
  Ahmed AU, Horbinski CM, Stupp R, Lesniak MS, and James CD, World Federation of Neuro-Oncology Meeting, Zurich, Switzerland, 1/7/2017
• Synergistic therapeutic efficacy via immunomodulatory platelet rich fibrin patch in combination with oncolytic adenovirus for the treatment of glioma
  Panek WK, Kim JW, Pituch KC, Kane RJ, Kanojia D, Cordero A, Miska J, Young JS, and Lesniak MS, World Federation of Neuro-Oncology Meeting, Zurich, Switzerland, 1/7/2017
• Combination RNAi therapy against glioblastoma stem cells via sustained lipopolymeric nanoparticle delivery delays tumor progression
  Dou Y, Khan OF, Suva ML, Panek WK, Wu M, Han Y, Ahmed AU, Balyasnikova IV, Anderson DG, Langer R, and Lesniak MS, World Federation of Neuro-Oncology Meeting, 1/7/2017
• PDX modeling of recurrent glioblastoma for testing salvage therapies
  James CD, Ahmed AU, Lesniak MS, Horbinski CM, Kumethkar, P, 21st Annual Meeting of the Society of Neuro-Oncology, Scottsdale, AZ, 1/20/2016
• Therapeutic targeting of the Wnt-beta catenin pathway alleviates glioma-induced immunosuppression and causes inhibition of glioma progression
  Chaudhuri S, Miska J, Chang A, Rashidi A, Zhang P, Yu D, Balyasnikova IV, and Lesniak MS, 21st Annual Meeting of the Society of Neuro-Oncology, Scottsdale, AZ, 1/20/2016
• Differential migration pathways of therapeutic stem cell carriers to glioma after intranasal delivery inspire genetic editing strategy for tumor tropism enhancement
  Yu D, Bonamici N, Tsai HM, Cheng SH, Wu M, Pituch K, Han Y, Chen CT, Lesniak MS, and Balyasnikova IV, 21st Annual Meeting of the Society of Neuro-Oncology, Scottsdale, AZ, 1/20/2016
• Dendritic cell based immunotherapy for malignant glioma by way of a noval dendritic cell targeted (scFvDEC205) adenoviral vector
  Kim WJ, Kane RJ, Young JS, Yu D, Miska J, Chang AL, Rashidi A, Ahmed AU, Balyasnikova IV, Lesniak MS, 21st Annual Meeting of the Society of Neuro-Oncology, Scottsdale, AZ, 1/20/2016
• EZH2-mediated ARL13B regulate ciliogenesis in GBM
  Atashi F, Hasan T, Lee G, Guo D, Park CH, Lesniak MS, James DC, and Ahmed AU, 21st Annual Meeting of the Society of Neuro-Oncology, Scottsdale, AZ, 1/20/2016
• Interleukin-8/CXCR2 signaling regulated epigenetic plasticity enhances tumorgenicity in glioblastoma
  Hasan T, Atashi F, Kim J, Lee G, Guo D, Park CH, Lesniak MS, Horbinski CM, James DC, and Ahmed AU, 21st Annual Meeting of the Society of Neuro-Oncology, Scottsdale, AZ, 1/20/2016
• The contribution of vascular co-option and tumor-derived endothelial cells to malignant glioma recurrence
  Auffinger B, Tobias AL, Degegeer M, Hansan T, Han Y, Lee G, Guo D, Lesniak MS, James DC, and Ahmed AU, 21st Annual Meeting of the Society of Neuro-Oncology, Scottsdale, AZ, 1/20/2016
• Stealth lipid nano-encapsulation enables efficacious therapeutic RNA interference in malignant glioma
  Zhang P, Yu D, Han Y, Wu M, and Lesniak MS, 21st Annual Meeting of the Society of Neuro-Oncology, Scottsdale, AZ, 1/20/2016
• Perpendicularly magnetized synthetic anti-ferromagnets as cancer therapeutics and more
  Vemulkar T, Mansell R, Petit D, Cowburn RP, Cheng Y, Murphy J, Lesniak MS, 13th Joint MMM-Intermag Conference, San Diego, CA, 1/15/2016
• Glioma microenivironment-derived CCL2 recruits regulatory T cells and myeloid-derived suppressor cells
  Lesniak MS, 21st International Conference on Brain Tumor Research and Therapy, Okinawa, Japan, 1/13/2016
• Glioma microenvironment-derived CCL2 recruits regulatory T cells and myeloid derived suppressor cells
  Chang AL, Miska J, Wainwright DA, Dey M, Yu D, Kanojia D, Pituch K, Qiao J, Pytel P, Han Y, Wu M, Zhang L, Ahmed AU, and Lesniak MS, Keystone Symposia: Cancer Vaccines: Targeting Cancer Genes for Immunotherapy, Whistler, Canada, 1/10/2016
• Neural stem cell mediated oncolytic virotherapy for ovarian cancer
  Majid AA, Mooney R, Gilchrist M, Lesniak MS, and Aboody K, American Society of Gene and Cell Therapy 19th Annual Meeting, Washington, DC, 1/7/2016
• Delayed clearance of neural stem cells enhances migration to glioma xenografts after intranasal delivery
  Spencer DA, Yu D, Morshed R, Han Y, Zhang L, Lesniak MS, Balyasnikova IV, 84th Annual Scientific Meeting of the American Association of Neurological Surgeons, Chicago, IL, 1/4/2016
• Toxicity and biodistribution of a conditionally replicative adenovirus vector, CRAd-S-pk7
  Hebert CD, Mann JF, and Lesniak MS, Society of Toxicology Annual Meeting, San Diego, CA, 1/26/2015
• Dendritic cell based immunotherapy of malignant glioma via a novel CD8alpha+ DC targeted adenoviral vector
  Kim WJ, Kane RJ, Young JS, Yu D, Miska J, Chang AL, Rashidi A, Ahmed AU, Balyasnikova IV, and Lesniak MS, Society for Neuro-Oncology Annual Meeting, San Antonio, TX, 1/22/2015
• Nono platform for dynamic in vivo tracking of neural stem cells to brain metastases of breast cancer
  Yu D, Cheng SH, Tsai HS, Kanojia D, Leoni L, Aboody KS, Chen CT, Lesniak MS, Balyasnikova IV, Society for Neuro-Oncology Annual Meeting, San Antonio, TX, 1/22/2015
• Intratumoral oncolytic adenoviral treatment modulates the glioma microenvironment and facilitates systemic tumor-antigen specific T cell therapy
  Qiao J, Dey M, Chang AL, Kim JW, Miska J, Ling A, Nettelbeck D, Han Y, Zhang L, and Lesniak MS, Charles B. Huggins Symposium, Gordon Center for Integrative Sciences, Chicago, IL, 1/19/2015
• IDO mediates contextually different outcomes between orthotopic and transgenic brain tumor models
  Zhai L, Gritsina G, Lauing AJ, Lesniak MS, McCusker R, Wainwright DA, 4th International Conference on Immunochemotherapy, Philadelphia, PA, 1/17/2015
• A sc-Fv based CAR to redirect T cells to IL12Ralpha2 positive glioma
  Krenciute G, Krebs S, Torres D, Lesniak MS, Balyasnikova IV, and Gottschalk S, American Society of Cell and Gene Therapy Annual Meeting; Pediatric Neuro-Oncology Basic and Translational Research Conference, San Diego, CA, 2015; New Orleans, LA, 2015, 1/16/2015
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Lectures

• Brain Metastases: The Forgotten Entity or the Future of Hope 
  Chicago, IL - 1/3/2017
• Stem cells as delivery vehicles in neuro-oncology 
  Washington, DC - 1/6/2015
• Stem cell carriers for oncolytic virotherapy of glioma 
  Washington, DC - 1/24/2014
• Cells as delivery vehicles 
  Chicago, IL, 2014; Osong, Korea, 2014 - 1/16/2014
• Intratumoral delivery of treatment 
  Tokyo, Japan - 1/9/2014
• Translation of immunobiology to immunotherapy 
  Tokyo, Japan - 1/9/2014
• Clinical trials and research in neuro-oncology 
  Buenos Aires, Argentina - 1/6/2014
• Awake Craniotomy 
  Buenos Aires, Argentina - 1/6/2014
• Clinical Trials in Neuro-Oncology 
  Buenos Aires, Argentina - 1/6/2014
• Cellular gene therapy approaches to gliomas 
  Buenos Aires, Argentina - 1/6/2014
• Brain environment promotes breast cancer metastatic colonization via microRNA epigenetic regulation 
  Chicago, IL - 1/24/2012
• Oncolytic and glioma: Is there a pot of gold at the end of the rainbow 
  Peoria, IL - 1/26/2010
• Optimizing Gene Therapy & Virotherapy Clinical Trials 
  Hyatt Capital Square, Columbus, OH - 1/10/2009
• Oncolytic viruses: The future of glioma viortherapy? 
  Philadelphia, PA - 1/24/2008
• Bio-Nano-Light Integration: A novel modality for treatment of brain cancer 
  Chicago, IL - 1/15/2008
• From bench to beside: How to engineer a common cold virus to destroy malignant brain tumors 
  Chicago, IL - 1/19/2007
• Design of oncolytic adenoviral vectors for malignant brain tumors 
  Chicago, IL - 1/18/2007
• Design of oncolytic adenoviral vector for glioma virotherapy 
  Boston, MA - 1/18/2007
• Targeting oncolytic adenoviruses for glioma gene therapy 
  Baltimore, MD - 1/10/2007
• Brain Tumors 
  Chicago, IL - 1/5/2007
• Creating an integrated multi-disciplinary brain tumor center 
  Chicago, IL - 1/22/2006
• What’s in the pipeline? New tools, new drug delivery methods, vaccines, and targeted treatments 
  Chicago, IL - 1/11/2006
• Anaplastic astrocytoma/Glioblastoma 
  Chicago, IL - 1/11/2006
• Gene Therapy for Brain Tumors 
  Istanbul, Turkey - 1/4/2006
• Immunotherapies against b-amyloid, ischemic damage, and brain tumors 
  Breckenridge, CO - 1/28/2005
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Other

• Nanoparticles destroy cancer with mechanical force 
  Lesniak MS
  http://news.feinberg.northwestern.edu/2016/02/nanoparticles-destroy-cancer-with-mechanical-force/
  1/1/2016
• Tomorrow’s Cancer Treatment? 
  Lesniak MS, Discovermagazine.com
  1/27/2015
• Patient centered innovation 
  Lesniak MS
  http://magazine.nm.org/fall-2015/features/patient-centered-innovation/
  1/1/2015
• A stem cell special delivery 
  Lesniak MS
  http://cen.acs.org/articles/91/web/2013/09/Stem-Cell-Special-Delivery.html
  1/10/2013
• Stem cell-conventional treatment combo offers new hope in fighting deadly brain cancer 
  Lesniak MS
  http://www.prweb.com/releases/2013/8/prweb11003765.htm
  1/7/2013
• New way to track stem cell migration could advance treatments for brain tumors and more 
  Lesniak MS
  http://www.prweb.com/releases/2013/9/prweb11095784.htm
  1/6/2013
• Stem cells utilized to target brain tumors 
  Lesniak MS
  http://stemsaveblog.com/tag/maciej-s-lesniak/
  1/4/2013
• Material scientists join oncologists to explore nano- and microtherapeutics 
  Lesniak MS, Journal of the National Cancer Institute New
  http://jnci.oxfordjournals.org/content/early/2011/01/17/jnci.djr015.full.pdf
  1/17/2011
• Healthbeat segment: Shaking up cancer 
  Lesniak MS, ABC News
  http://abclocal.go.com/wls/story?section=news/health&id=7245605
  1/28/2010
• Nanomaterials may help fight cancer 
  Lesniak MS, Science Daily
  http://www.sciencedaily.com/releases/2010/02/100210211731.htm
  1/12/2010
• Emerging therapies for malignant glioma 
  Lesniak MS
  http://www.sirkethaberleri.com/haber-gorselleri/prof-dr-maciej-s-lesniak-42221
  1/12/2010
• Breast cancer team combines quality of life with quality of treatment 
  Lesniak MS, University of Chicago News
  http://www.uchospitals.edu/specialties/cancer/patient-stories/eloise-breast-cancer.html
  1/12/2010
• Argonne scientists discover novel materials approach to fighting cancer 
  Lesniak MS, UChicago News
  http://news.uchicago.edu/article/2010/02/10/argonne-scientists-discover-novel-materials-approach-fighting-cancer
  1/10/2010
• Nano-bio material kills cancer cells, leaves healthy cells unharmed 
  Lesniak MS, Innovation Toronto
  http://www.innovationtoronto.com/2010/09/nano-bio-material-kills-cancer/
  1/10/2010
• Nanomaterial-antibody combination targets cancers cells 
  Lesniak MS, Argonne National Laboratory News
  http://www.anl.gov/Media_Center/Argonne_News/Completed_PDFs/A_News090831.pdf
  1/31/2009
• Titanium nanoparticles bonded to biological material used in study of brain cancer treatment 
  Lesniak MS, ASM International
  http://smst.asminternational.org/portal/site/www/NewsItem/?vgnextoid=a26e5c9017153210VgnVCM100000621e010aRCRD
  1/25/2009
• Titanium dioxide nanoparticles catalyze brain tumor death 
  Lesniak MS, New-Medical
  http://www.news-medical.net/news/20090923/Titanium-dioxide-nanoparticles-catalyze-brain-tumor-death.aspx
  1/23/2009
• Argonne, University of Chicago scientists develop targeted cancer treatment using nanomaterials 
  Lesniak MS
  1/20/2009
• Scientists use titanium dioxide nanoparticles to kill cancer cells, sparing healthy ones 
  Lesniak MS, Thaindian News
  http://www.thaindian.com/newsportal/health/scientists-use-titanium-dioxide-nanoparticles-to-kill-cancer-cells-sparing-healthy-ones_100235267.html
  1/20/2009
• U.S. scientists develop targeted cancer treatment using nanomaterials 
  Lesniak MS, Manila Bulleting Publishing Corporation
  http://www.mb.com.ph/articles/216800/us-scientists-develop-targeted-cancer-treatment-using-nanomaterials
  1/20/2009
• Nano-bio material kills cancer cells, leaving healthy cell unharmed 
  Lesniak MS, Science Daily News
  http://www.sciencedaily.com/releases/2009/08/090819123943.htm
  1/19/2009
• Scientists develop targeted cancer treatment using nanomaterials 
  Lesniak MS, Physorg
  http://www.physorg.com/news169904314.html
  1/19/2009
• Cancer seeking nanomissile 
  Lesniak MS, Nanowerk
  http://www.nanowerk.com/news/newsid=12224.php
  1/19/2009
• Nanomaterials work to treat brain tumors 
  Lesniak MS, Science Codex
  http://www.sciencecodex.com/argonne_university_of_chicago_scientists_develop_targeted_cancer_treatment_using_nanomaterials
  1/19/2009
• Killing cancer cells with nanoparticles bonded to biological material 
  Lesniak MS, AZO Nanotechnology
  http://www.azonano.com/news.asp?newsID=13219
  1/19/2009
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