MahaliaSDesruisseauxMD

PubMed

• COVID-19 Convalescent Plasma Therapy: Long-term Implications.
  Li, Y., Goldfeld, K., Cobb, G., Sturm-Reganato, C., Hochman, J., , Yoon, H., Ostrosky-Zeichner, L., Jayaweera, D., Philley, J., Desruisseaux, M., Keller, M., Pirofski,...> ;Open Forum Infectious Diseases. 2024 Jan 1
• Effects of anti-tau immunotherapy on reactive microgliosis, cerebral endotheliopathy, and cognitive function in an experimental model of cerebral malaria.
  Oscar B Akide Ndunge, Henry J Shikani, Minxian Dai, Brandi D Freeman, Mahalia S Desruisseaux> ;Journal of Neurochemistry. 2023 Nov 1
• Integrated Care Models: HIV and Substance Use.
  Katherine Hill, Irene Kuo, Sheela V Shenoi, Mahalia S Desruisseaux, Sandra A Springer> ;Current HIV/AIDS Reports. 2023 Oct 1
• Building an Infectious Disease Diversity, Equity, and Antiracism (ID2EA) Curriculum: A Single Center's Experience and Reflections.
  Shana E Gleeson, Heidi Zapata, Meghan E Bathgate, Brinda Emu, Jennifer Frederick, Gerald Friedland, Marjorie P Golden, Jaimie P Meyer, Joanna Radin, Robert Sideleau, A...> ;Clinical Infectious Diseases. 2023 Sep 11
• 44 citations
  Efficacy and Safety of COVID-19 Convalescent Plasma in Hospitalized Patients: A Randomized Clinical Trial.
  Mila B Ortigoza, Hyunah Yoon, Keith S Goldfeld, Andrea B Troxel, Johanna P Daily, Yinxiang Wu, Yi Li, Danni Wu, Gia F Cobb, Gillian Baptiste, Mary O'Keeffe, Marilou O ...> ;JAMA Internal Medicine. 2022 Feb 1
• 22 citations
  Early but not late convalescent plasma is associated with better survival in moderate-to-severe COVID-19.
  Neima Briggs, Michael V. Gormally, Fangyong Li, Sabrina L. Browning, Miriam M. Treggiari, Alyssa Morrison, Maudry Laurent-Rolle, Yanhong Deng, Jeanne E. Hendrickson, C...> ;Plos One. 2021 Jul 28
• 4 citations
  Inclusion, Diversity, Access, and Equity (IDA&E) Roadmap: Infectious Diseases Society of America’s Commitment to the Future
  Mahalia S. Desruisseaux, Tina Q. Tan> ;The Journal of Infectious Diseases. 2020 Sep 14
• 18 citations
  Endothelins in inflammatory neurological diseases
  Pedro D'Orléans-Juste, Oscar Bate Akide Ndunge, Louisane Desbiens, Herbert B. Tanowitz, Mahalia S. Desruisseaux> ;Pharmacology & Therapeutics. 2019 Feb 1
• 11 citations
  Trypanosoma cruzi Produces the Specialized Proresolving Mediators Resolvin D1, Resolvin D5, and Resolvin E2
  Romain A. Colas, Anthony W. Ashton, Shankar Mukherjee, Jesmond Dalli, Oscar B. Akide-Ndunge, Huan Huang, Mahalia S. Desruisseaux, Fangxia Guan, Linda A. Jelicks, Fabia...> ;Infection and Immunity. 2018 Apr 1
• 10 citations
  Endothelin-1 Treatment Induces an Experimental Cerebral Malaria-Like Syndrome in C57BL/6 Mice Infected with Plasmodium berghei NK65.
  Yuri C. Martins, Brandi D. Freeman, Oscar Bate Akide Ndunge, Louis M. Weiss, Herbert B. Tanowitz, Mahalia S. Desruisseaux> ;The American Journal of Pathology. 2016 Nov 1
• 16 citations
  Endothelin-1 Mediates Brain Microvascular Dysfunction Leading to Long-Term Cognitive Impairment in a Model of Experimental Cerebral Malaria.
  Brandi D. Freeman, Yuri C. Martins, Oscar B. Akide-Ndunge, Fernando P. Bruno, Hua Wang, Herbert B. Tanowitz, David C. Spray, Mahalia S. Desruisseaux> ;Plos Pathogens. 2016 Mar 31
• 63 citations
  Endothelin-1 and its role in the pathogenesis of infectious diseases.
  Brandi D. Freeman, Fabiana S. Machado, Herbert B. Tanowitz, Mahalia S. Desruisseaux> ;Life Sciences. 2014 Nov 24
• 27 citations
  Alterations in glucose homeostasis in a murine model of Chagas disease
  Fnu Nagajyothi, Regina Kuliawat, Christine M. Kusminski, Fabiana S. Machado, Mahalia S. Desruisseaux, Dazhi Zhao, Gary J. Schwartz, Huan Huang, Chris Albanese, Michael...> ;The American Journal of Pathology. 2013 Mar 1
• 17 citations
  Imaging of small-animal models of infectious diseases.
  Linda A. Jelicks, Michael P. Lisanti, Fabiana S. Machado, Louis M. Weiss, Herbert B. Tanowitz, Mahalia S. Desruisseaux> ;The American Journal of Pathology. 2013 Feb 1
• 20 citations
  Altered regulation of Akt signaling with murine cerebral malaria, effects on long-term neuro-cognitive function, restoration with lithium treatment.
  Minxian Dai, Brandi D. Freeman, Henry J. Shikani, Fernando P. Bruno, J. Elias Collado, Rolando Macias, Sandra E. Reznik, Peter Davies, David C. Spray, Herbert B. Tanow...> ;Plos One. 2012 Oct 17
• 54 citations
  Cerebral Malaria: We Have Come a Long Way
  Henry J. Shikani, Brandi D. Freeman, Michael P. Lisanti, Louis M. Weiss, Herbert B. Tanowitz, Mahalia S. Desruisseaux> ;The American Journal of Pathology. 2012 Nov 1
• 21 citations
  The novel ETA receptor antagonist HJP-272 prevents cerebral microvascular hemorrhage in cerebral malaria and synergistically improves survival in combination with an a...
  Minxian Dai, Brandi D. Freeman, Fernando P. Bruno, Henry J. Shikani, Herbert B. Tanowitz, Louis M. Weiss, Sandra E. Reznik, Ralph Stephani, Mahalia S. Desruisseaux> ;Life Sciences. 2012 Oct 15
• 56 citations
  Response of Adipose Tissue to Early Infection With Trypanosoma cruzi (Brazil Strain)
  Fnu Nagajyothi, Mahalia S. Desruisseaux, Fabiana S. Machado, Rajendra Upadhya, Dazhi Zhao, Mauro M. Teixeira, Chris Albanese, Michael P. Lisanti, Streamson C. Chua, Lo...> ;The Journal of Infectious Diseases. 2012 Mar 1
• 67 citations
  Trypanosoma cruzi utilizes the host low density lipoprotein receptor in invasion.
  Fnu Nagajyothi, Louis M. Weiss, David L. Silver, Mahalia S. Desruisseaux, Philipp E. Scherer, Joachim Herz, Herbert B. Tanowitz> ;Plos Neglected Tropical Diseases. 2011 Feb 1
• 19 citations
  Adipose tissue, diabetes and Chagas disease.
  Herbert B. Tanowitz, Linda A. Jelicks, Fabiana S. Machado, Lisia Esper, Xiaohua Qi, Mahalia S. Desruisseaux, Streamson C. Chua, Philipp E. Scherer, Fnu Nagajyothi> ;Advances in Parasitology. 2011 Jan 1
• 29 citations
  Crucial Role of the Central Leptin Receptor in Murine Trypanosoma cruzi (Brazil Strain) Infection
  Fnu Nagajyothi, Dazhi Zhao, Fabiana S. Machado, Louis M. Weiss, Mahalia S. Desruisseaux, Yang Zhao, Stephen M. Factor, Huan Huang, Chris Albanese, Mauro M. Teixeira, P...> ;The Journal of Infectious Diseases. 2010 Oct 1
• 15 citations
  Alterations in the Brain Transcriptome in Plasmodium Berghei ANKA Infected Mice
  Mahalia S. Desruisseaux, Dumitru A. Iacobas, Sanda Iacobas, Shankar Mukherjee, Louis M. Weiss, Herbert B. Tanowitz, David C. Spray> ;Journal of Neuroparasitology. 2010 Oct 1
• 40 citations
  Persistent cognitive and motor deficits after successful antimalarial treatment in murine cerebral malaria
  Minxian Dai, Sandra E. Reznik, David C. Spray, Louis M. Weiss, Herbert B. Tanowitz, Maria Gulinello, Mahalia S. Desruisseaux> ;Microbes and Infection. 2010 Dec 1
• 22 citations
  Cerebral malaria: a vasculopathy.
  Mahalia S. Desruisseaux, Fabiana S. Machado, Louis M. Weiss, Herbert B. Tanowitz, Linnie M. Golightly> ;The American Journal of Pathology. 2010 Mar 1
• 26 citations
  Chagas disease, adipose tissue and the metabolic syndrome
  Fnu Nagajyothi, Mahalia S. Desruisseaux, Louis M. Weiss, Streamson C. Chua, Chris Albanese, Fabiana S. Machado, Lisia Esper, Michael P. Lisanti, Mauro M. Teixeira, Phi...> ;Memorias Do Instituto Oswaldo Cruz. 2009 Jul 1
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Journal Articles

• Endothelin-1 and its role in the pathogenesis of infectious diseases  
  Freeman BD, Machado FS, Tanowitz HB, Desruisseaux MS, Life Sciences, 1/1/2014
• Imaging of small-animal models of infectious diseases  
  Jelicks LA, Lisanti MP, Machado FS, Weiss LM, Tanowitz HB, Desruisseaux MS, American Journal of Pathology, 1/1/2013
• Alterations in glucose homeostasis in a murine model of Chagas disease  
  Nagajyothi F, Kuliawat R, Kusminski CM, Machado FS, Desruisseaux MS, Zhao D, Schwartz GJ, Huang H, Albanese C, Lisanti MP, Singh R, Li F, Weiss LM, Factor SM, Pessin J..., American Journal of Pathology, 1/1/2013
• Response of adipose tissue to early infection with Trypanosoma cruzi (Brazil strain)  
  Nagajyothi F, Desruisseaux MS, Machado FS, Upadhya R, Zhao D, Schwartz GJ, Teixeira MM, Albanese C, Lisanti MP, Chua SC Jr, Weiss LM, Scherer PE, Tanowitz HB, J Infect Dis, 1/1/2012
• Cerebral malaria: we have come a long way  
  Shikani HJ, Freeman B, Lisanti MP, Weiss LM, Tanowitz HB, Desruisseaux MS, American Journal of Pathology, 1/1/2012
• Altered regulation of Akt Signaling with Murine Cerebral Malaria, Effects on Long-term Neuro-cognitive Function, Restoration with Lithium Treatment  
  Dai M, Freeman B, Shikani HJ, Bruno FP, Collado JE, Macias R, Reznik SE, Davies P, Spray DC, Tanowitz HB, Weiss LM, Desruisseaux MS, PLoS One, 1/1/2012
• Cerebral malaria: a vasculopathy  
  Desruisseaux MS, Machado FS, Weiss LM, Tanowitz HB, Golightly LM, American Journal of Pathology, 1/1/2010
• Crucial role of the central leptin receptor in murine Trypanosoma cruzi (Brazil strain) infection  
  Nagajyothi F, Zhao D, Machado FS, Weiss LM, Schwartz GJ, Desruisseaux MS, Zhao Y, Factor SM, Huang H, Albanese C, Teixeira MM, Scherer PE, Chua SC Jr, Tanowitz HB, Journal of Infectious Diseases, 1/1/2010
• Alterations in the brain transcriptome in Plasmodium berghei ANKA infected mice  
  Desruisseaux MS, Iacobas DA, Iacobas S, Mukherjee S, Weiss LM, Tanowitz HB, Spray DC, Journal of Neuroparasitology, 1/1/2010
• Persistent cognitive and motor deficits after successful antimalarial treatment in murine cerebral malaria  
  Dai M, Reznik SE, Spray DC, Weiss LM, Tanowitz HB, Gulinello M, Desruisseaux MS, Microbes and Infection, 1/1/2010
• Perspectives on adipose tissue, Chagas disease and implications for the metabolic syndrome  
  Nagajyothi F, Desruisseaux M, Jelicks LA, Machado F, Chua SC, Scherer P, Tanowitz HB, Interdisciplinary Perspectives on Infectious Diseases, 1/1/2009
• Cognitive dysfunction in mice infected with Plasmodium berghei ANKA  
  Desruisseaux MS, Gulinello M, Smith DN, Lee SC, Tsuji M, Weiss LM, Spray DC, Tanowitz HB, Journal of Infectious Diseases, 1/1/2008
• Trypanosoma cruzi infection of cultured adipocytes results in an inflammatory phenotype  
  Nagajyothi F, Desruisseaux MS, Thiruvur N, Weiss LM, Braunstein VL, Albanese C, Teixeira MM, de Almeida CJ, Lisanti MP, Scherer PE, Tanowitz HB, Obesity, 1/1/2008
• Thromboxane A2 is a key regulator of pathogenesis during Trypanosoma cruzi infection  
  Ashton AW, Mukherjee S, Nagajyothi F, Huang H, Braunstein VL, Desruisseaux MS, Factor SM, Lopez L, Berman JW, Wittner M, Scherer PE, Capra V, Coffman TM, Serhan CN, Go..., Journal of Experimental Medicine, 1/1/2007
• Endothelin in a murine model of cerebral malaria  
  Machado FS, Desruisseaux MS, Nagajyothi, Kennan RP, Hetherington HP, Wittner M, Weiss LM, Lee SC, Scherer PE, Tsuji M, Tanowitz HB, Experimental Biology and Medicine, 1/1/2006
• Trypanosoma cruzi infection induces proliferation of vascular smooth muscle cells  
  Hassan GS, Mukherjee S, Nagajyothi, Weiss LM, Petkova SB, de Almeida CJG, Huang H, Desruisseaux MS, Bouzahzah B, Pestell RG, Albanese C, Christ GJ, Lisanti MP, Tanowit..., Infection and Immunity, 1/1/2006
• Reduced Cerebral Blood Flow and N-Acetyl Aspartate in a Murine Model of Cerebral Malaria  
  Kennan RP, Machado FS, Lee SC, Desruisseaux MS, Wittner M, Tsuji M, Tanowitz HB, Parasitology Research, 1/1/2005
• Diagnostic puzzlers: Chronic cough in a woman with HIV infection  
  Desruisseaux M, Meyerhoff R, Arunabh T, Kaplan M, Journal of Respiratory Diseases, 1/1/2004
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Books/Book Chapters

• The Blood Brain Barrier in Health and Disease 
  Chapter: The Brain Microvasculature in Cerebral Malaria 
  Page 68 - 117K Dorovini-Zis, M Stins, MS Desruisseaux, YC Martins, H Van der HeydeEditors: Katerina Dorovini-Zis.Taylor and Francis Group, LLC/ CRC Press2015
• Vascular Responses to Pathogens 
  Chapter: Trypanosoma cruzi and Chagas Disease: Innate Immunity, ROS, and Cardiovascular System 
  Page 183 - 194Tanowitz HB, Wen JJ, Machado FS, Desruisseaux MS, Robello C, Garg NJEditors: Felicity NE Gavins, Karen Y Stokes.Academic Press2015
• Advances in Parasitology (Vol. 76: Chagas Disease). 
  Chapter: Adipose tissue, diabetes and Chagas disease. 
  Page 235 - 250Tanowitz HB, Jelicks LA, Machado FS, Esper L, Qi X, Desruisseaux MS, Chua SC, Scherer PE, Nagajyothi FEditors: Louis M Weiss and Herbert B Tanowitz.Academic Press2011
• Blood-Brain Interfaces – From Ontogeny to Artificial Barriers. 
  Chapter: Human Parasitic Disease in the context of the Blood-Brain Barrier - Effects, Interactions, and Transgressions. 
  Page 671 - 696Desruisseaux MS, Tanowitz HB, Weiss LM, Mott A, Milner DAEditors: Dermietzel R, Spray D, Nedergaard M.Wiley VCH, Weinheim2006
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Abstracts/Posters

• Akide-Ndunge OB, Desruisseaux M, ASTMH 64th Annual Meeting, Philadelphia, PA, 1/1/2015
• Cerebral vasculature and cognitive impairment in acute Trypanosoma cruzi infection.
  Barrie U, Freeman B, Tanowitz H, Desruisseaux M, ASTMH 64th Annual Meeting, Philadelphia, PA, 1/1/2015
• Experimental Cerebral Malaria Induces Cerebral Vascular Dysfunction and Cognitive Impairment via Endothelin A Receptor Signaling.
  Freeman BD, Martins YC, Desruisseaux MS, ASTMH 64th Annual Meeting, Philadelphia, PA, 1/1/2015
• Cerebral vasculature and cognitive impairment in acute Trypanosoma cruzi infection.
  Barrie U, Freeman B, Tanowitz H, Desruisseaux M, XXVIIth International Symposium on Cerebral Blood Flow, Metabolism and Function, Vancouver, British Columbia, Canada, 1/1/2015
• The role of endothelin-1 in the vascular pathobiology of cerebral malaria.
  Freeman BD, Martins YC, Desruisseaux MS, ASTMH 63rd Annual Meeting, New Orleans, LA, 1/1/2014
• Tau abnormalities, inflammation and axonal damage in murine cerebral malaria.
  Shikani H, Desruisseaux M, ASTMH 63rd Annual Meeting, New Orleans, LA, 1/1/2014
• The role of endothelin in the vascular pathology of cerebral malaria.
  Freeman BD, Martins YC, Desruisseaux MS, Malaria: Advances in Pathophysiology, Biology and Drug Development, New York Academy of Sciences World Malaria Day Symposium, New York, NY, 1/1/2014
• Endothelin-1 treatment induces experimental cerebral malaria in Plasmodium berghei NK65 infected mice.
  Martins YC, Tanowitz HB, Weiss LM, Desruisseaux MS, Malaria: Advances in Pathophysiology, Biology and Drug Development, New York Academy of Sciences World Malaria Day Symposium, New York, NY, 1/1/2014
• Cerebral malaria: A tauopathy?
  Shikani H, Desruisseaux M, Malaria: Advances in Pathophysiology, Biology and Drug Development, New York Academy of Sciences World Malaria Day Symposium, New York, NY, 1/1/2014
• Building Bridges: Improving Antibiotic Prescribing in the Emergency Department.
  Madaline T, Feldmesser M, Chung P, Daily J, Desruisseaux M, Hochman S, Keller M, Leviton I, Murphy K, Sharma A, Pearlman S, Katz N, White D, Pirofski L, Ost..., IDWeek Meeting of the Infectious Diseases Society of America, Philadelphia, PA, 1/1/2014
• Using PET-scan to monitor brain metabolism in a murine model of cerebral malaria.
  Bruno FP, Freeman BD, Koba WR, Dai M, Jelicks LA, Fine EJ, Desruisseaux MS, American Neurological Association Annual Meeting, New Orleans, LA, 1/1/2013
• Near-infrared fluorescent imaging of matrix metalloproteinases as an index of brain inflammation in cerebral malaria.
  Bruno FP, Shikani HJ, Freeman BD, Dai M, Jasmin F, Tanowitz HB, Weiss LM, Spray DC, Desruisseaux MS, American Neurological Association Annual Meeting, New Orleans, LA, 1/1/2013
• The role of endothelin-1 in the vascular pathobiology of cerebral malaria.
  Freeman BD, Dai M, Desruisseaux MS, Thirteenth International Conference on Endothelin, Tokyo, Japan, 1/1/2013
• Endothelin-1 induces experimental cerebral malaria during Plasmodium berghei NK65 infection.
  Martins YC, Tanowitz HB, Weiss LM, Desruisseaux MS, Thirteenth International Conference on Endothelin, Tokyo, Japan, 1/1/2013
• Near-infrared fluorescent imaging: A novel technique to assess brain pathology and severity in experimental cerebral malaria.
  Bruno FP, Shikani HJ, Dai M, Freeman BD, Jasmin J, Tanowitz HB, Weiss LM, Spray DC, Desruisseaux MS, ASTMH 62nd Annual Meeting, Washington, DC, 1/1/2013
• Endothelin-1 treatment induces experimental cerebral malaria during Plasmodium berghei NK655 infection.
  Martins YC, Tanowitz HB, Weiss LM, Desruisseaux MS, ASTMH 62nd Annual Meeting, Washington, DC, 1/1/2013
• The role of tau protein in the neuropathogenesis of cerebral malaria.
  Shikani H, Desruisseaux M, ASTMH 62nd Annual Meeting, Washington, DC, 1/1/2013
• Positron Emission Tomography- an in vivo imaging system for follow up encephalic metabolism in cerebral malaria.
  Bruno FP, Freeman BD, Koba WR, Jelicks LA, Fine EJ, Desruisseaux MS, ASTMH 61st Annual Meeting, Atlanta, GA, 1/1/2012
• Near-infrared fluorescent imaging: A Novel technique to assess inflammation in experimental cerebral malaria.
  Bruno FP, Freeman BD, Tanowitz HB, Weiss LM, Spray DC, Desruisseaux MS, ASTMH 61st Annual Meeting, Atlanta, GA, 1/1/2012
• Endothelin-1 In Vascular Pathology And Its Role In The Pathogenesis Of Cerebral Malaria.
  Freeman B, Dai M, Desruisseaux MS, ASTMH 61st Annual Meeting, Atlanta, GA, 1/1/2012
• Cerebral Malaria: A Tauopathy?
  Shikani H, Desruisseaux MS, ASTMH 61st Annual Meeting, Atlanta, GA, 1/1/2012
• A novel endothelin receptor antagonist increases rates of cerebral malaria survival.
  Dai M, Shikani HJ, Stephani RA, Reznik S, Tanowitz HB, Weiss LM, Desruisseaux MS, Twelfth International Conference on Endothelin, Cambridge, United Kingdom, 1/1/2011
• Dynamic imaging studies to monitor metabolic changes in murine cerebral malaria.
  Bruno FP, Freeman BD, Jasmin, Koba WR, Weiss LM, Spray DC, Fine EJ, Tanowitz HB, Desruisseaux MS, ASTMH 60th Annual Meeting, Philadelphia, PA, 1/1/2011
• Regulation of Akt/GSK-3 and neuroprotection with cerebral malaria.
  Dai M, Zhao D, Shikani H, Reznik Sa, Tanowitz H, Weiss L, Desruisseaux M, ASTMH 60th Annual Meeting, Philadelphia, PA, 1/1/2011
• Post-translational modification of tau protein in the brains of mice infected with P. berghei ANKA.
  Desruisseaux MS, Davies P, Nagajyothi F, Fine EJ, Weis LM, Tanowitz HB, ASTMH 58th Annual Meeting, Washington, DC, 1/1/2009
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Lectures

• Vasomodulatory mediators, cognitive function, and survival in experimental cerebral malaria 
  ASTMH 65th Annual Meeting, Atlanta GA - 11/16/2016
• Cerebral malaria: Cognition, survival and the role of vasomodulation 
  Infectious Diseases Grand Rounds, Memorial Sloan Kettering Cancer Center - 9/16/2016
• Neuropathology of Cerebral Malaria. 
  The New York Academy of Sciences World Malaria Day, New York NY - 4/25/2014
• Altered neuronal function and neurological salvage in cerebral malaria. 
  Albert Einstein College of Medicine - 11/2/2011
• Guest Lecturer 
  Infectious Diseases Grand Rounds, Memorial Sloan Kettering Cancer Center - 2009
• Colin Powell Post-Doctoral Fellowship 
  Infectious Diseases Society of America 43rd Annual Meeting, San Francisco CA - 2005
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