MaheswariSenthilMD

PubMed

• Regional Therapy Approaches for Gastric Cancer with Limited Peritoneal Disease.
  Li, A., Tajik, F., Khan, A., Radhakrishnan, V., Sedighim, S., Dayyani, F., Senthil, M.> ;Journal of Gastrointestinal Cancer. 2024 Jan 26
• Amplifying Curcumin's Antitumor Potential: A Heat-Driven Approach for Colorectal Cancer Treatment.
  Kabagwira, J., Fuller, R., Vallejos, P., Sugiono, C., Andrianarijaona, V., Chism, J., O'Leary, M., Langridge, W., Wall, N., Molina, D., Senthil, M.> ;Oncotargets and Therapy. 2024 Jan 1
• Response to letter to the editor "Elevating Standards: A Comprehensive Model for Peritoneal Surface Malignancy Management in Developing Healthcare Systems".
  Sedighim, S., Senthil, M.> ;Journal of Surgical Oncology. 2024 Mar 1
• 7 citations
  Global Cancer Surgery: pragmatic solutions to improve cancer surgery outcomes worldwide.
  Are, C., Murthy, S., Sullivan, R., Schissel, M., Chowdhury, S., Alatise, O., Anaya, D., Are, M., Balch, C., Bartlett, D., Brennan, M., Cairncross, L., Clark, M., Deo, ...> ;The Lancet. Oncology. 2023 Dec 1
• 2 citations
  Adoption of cytoreductive surgery in the management of peritoneal malignancies-Global trends.
  Shaina Sedighim, Aaqil Khan, Amy Y Li, Fatemeh Tajik, Vinodh K Radhakrishnan, Oliver Eng, Kiran Turaga, Maheswari Senthil> ;Journal of Surgical Oncology. 2023 Nov 1
• Effect of a Same-Day-Appointment Initiative on Access-Related Benchmarks in Radiation Oncology.
  Allen M Chen, Andrew D Garcia, Marcela Alexandrescu, Annie Truong, Maheswari Senthil> ;Practical Radiation Oncology. 2023 Sep 23
• Role of Iterative Normothermic Intraperitoneal Paclitaxel Combined with Systemic Chemotherapy in the Management of Gastric Peritoneal Carcinomatosis.
  Maheswari Senthil, Farshid Dayyani> ;Annals of Surgical Oncology. 2024 Feb 1
• 9 citations
  Surgical versus non-surgical management for patients with malignant bowel obstruction (S1316): a pragmatic comparative effectiveness trial.
  Robert S Krouse, Garnet L Anderson, Kathryn B Arnold, Cynthia A Thomson, Valentine N Nfonsam, Mazin F Al-Kasspooles, Joan L Walker, Virginia Sun, Angeles Alvarez Secor...> ;The Lancet. Gastroenterology & Hepatology. 2023 Oct 1
• Readmission and Disposition in Patients With Malignant Bowel Obstructions Following Gastrostomy Tube.
  Jingjing Yu, Brittany G Sullivan, Ninh T Nguyen, Samuel F Hohmann, Alyssa H Harris, Dejan Micic, Kiran K Turaga, Maheswari Senthil, Oliver S Eng> ;The American Surgeon. 2023 Dec 1
• 1 citations
  A Novel Assessment of Metabolic Pathways in Peritoneal Metastases from Low-Grade Appendiceal Mucinous Neoplasms.
  Eric A Hanse, Tianhong Wang, Delia Tifrea, Maheswari Senthil, Alex C Kim, Mei Kong, Oliver S Eng> ;Annals of Surgical Oncology. 2023 Aug 1
• 1 citations
  Durable Response after Repeat Cytoreductive Surgery (CRS) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in a Patient with Extensive Mucinous Adenocarcinoma of ...
  Dalia Kaakour, Garrett Ward, Maheswari Senthil, Farshid Dayyani> ;Diseases. 2023 Apr 6
• ASO Visual Abstract: Plasma Exosome Gene Signature Differentiates Colon Cancer from Healthy Controls.
  Paul A Vallejos, Amber Gonda, Jingjing Yu, Brittany G Sullivan, Arsha Ostowari, Mei Li Kwong, Audrey Choi, Matthew J Selleck, Janviere Kabagwira, Ryan N Fuller, Daniel...> ;Annals of Surgical Oncology. 2023 Jun 1
• 2 citations
  Phase II clinical trial of sequential treatment with systemic chemotherapy and intraperitoneal paclitaxel for gastric and gastroesophageal junction peritoneal carcinom...
  Maheswari Senthil, Farshid Dayyani> ;BMC Cancer. 2023 Mar 4
• ASO Author Reflections: Liquid Biopsy in Gastrointestinal Malignancies: Role of Exosomes.
  Amber Gonda, Maheswari Senthil> ;Annals of Surgical Oncology. 2023 Jun 1
• 6 citations
  Exosomes as a Source of Biomarkers for Gastrointestinal Cancers.
  Jingjing Yu, Arsha Ostowari, Amber Gonda, Kiarash Mashayekhi, Farshid Dayyani, Christopher C W Hughes, Maheswari Senthil> ;Cancers. 2023 Feb 16
• Routine Omentectomy During Cytoreductive Surgery for Peritoneal Surface Malignancies.
  Stephanie Young, Jingjing Yu, Maheswari Senthil> ;Annals of Surgical Oncology. 2023 Feb 1
• The role of cytoreductive surgery and intraperitoneal chemotherapy in gastric cancer.
  Stephanie Young, Arsha Ostowari, Jingjing Yu, Oliver S Eng, Farshid Dayyani, Maheswari Senthil> ;Clinical Advances in Hematology & Oncology. 2022 Nov 1
• 1 citations
  Exosomal proteins as a source of biomarkers in colon cancer-derived peritoneal carcinomatosis - A pilot study.
  Paul A Vallejos, Ryan N Fuller, Janviere Kabagwira, Mei Li Kwong, Amber Gonda, James R W McMullen, Natasha Le, Matthew J Selleck, Lance D Miller, Christopher C Perry, ...> ;Proteomics. Clinical Applications. 2023 Mar 1
• ASO Visual Abstract: Circulating Tumor DNA is Unreliable to Detect Somatic Gene Alterations in Gastrointestinal Peritoneal Carcinomatosis.
  Brittany G Sullivan, Angelina Lo, Jingjing Yu, Amber Gonda, Farideh Dehkordi-Vakil, Farshid Dayyani, Maheswari Senthil> ;Annals of Surgical Oncology. 2023 Jan 1
• ASO Author Reflections: Challenges of Circulating Tumor DNA in the Management of Gastrointestinal Peritoneal Carcinomatosis.
  Brittany G Sullivan, Farshid Dayyani, Maheswari Senthil> ;Annals of Surgical Oncology. 2023 Jan 1
• 13 citations
  Circulating Tumor DNA is Unreliable to Detect Somatic Gene Alterations in Gastrointestinal Peritoneal Carcinomatosis.
  Brittany G Sullivan, Angelina Lo, Jingjing Yu, Amber Gonda, Farideh Dehkordi-Vakil, Farshid Dayyani, Maheswari Senthil> ;Annals of Surgical Oncology. 2023 Jan 1
• Prevalence of Primary Liver Cancer is Affected by Place of Birth in Hispanic People Residing in the United States: All of Us Research Program Report.
  Jingjing Yu, Brittany G Sullivan, Girish N Senthil, Amber Gonda, Farideh Dehkordi-Vakil, Belinda Campos, Farshid Dayyani, Maheswari Senthil> ;The American Surgeon. 2022 Oct 1
• A phase Ib feasibility trial of response adapted neoadjuvant therapy in gastric cancer (RANT-GC).
  Farshid Dayyani, Brian R Smith, Ninh T Nguyen, Shaun Daly, Marcelo W Hinojosa, Steven N Seyedin, Jeffrey Kuo, Jason B Samarasena, John G Lee, Thomas H Taylor, May T Ch...> ;Future Oncology. 2022 Jul 1
• Spontaneous Fluctuations of Tumor-Informed Circulating Tumor DNA at Low Levels.
  Farshid Dayyani, Maheswari Senthil> ;JCO Precision Oncology. 2022 Jul 1
• 5 citations
  Utility of tumor-informed circulating tumor DNA in the clinical management of gastrointestinal malignancies.
  Danielle Brazel, Priyanka Kumar, Liudmila N Schafer, Benjamin Eidenschink, Maheswari Senthil, Farshid Dayyani, Zhang, S.> ;Journal of Gastrointestinal Oncology. 2021 Dec 1
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Journal Articles

• Sexual and Urinary Outcomes in Robotic Rectal Surgery: Review of the Literature and Technical Considerations  
  Matthew J Selleck, Danielle K Craigg, Mark E Reeves, Maheswari Senthil, Fabrizio Luca, Carlos A Garberoglio, Updates in Surgery
• Role of the cancer center when using lymph node count as a quality measure for gastric cancer surgery  
  Morgan JW, Ji L, Friedman G, Senthil M, Dyke C, Lum SS, JAMA Surg, 1/1/2015
• Aryl hydrocarbon receptor ligand 5F203 induces oxidative stress that triggers DNA damage in human Breast cancer cells  
  Mclean LS, Watkins CN, Campbell P, Zylsatra D, Rowland L, Amis LH, Scott L, Babb CE, Livingston WJ, Darwanto A, Davis WL Jr, Senthil M, Sowers LC, Brantley E, Chem Res Toxicol, 1/1/2015
• The Prevalence of overweight and obesity in a breast clinic population: consideration for weight loss as a therapeutic intervention  
  Kim A, Scharf K, Senthil M, Solomon N, Garberoglio C, Lum SS, Surg Obes Relat Dis, 1/1/2014
• The American Society of Peritoneal Surface Malignancies evaluation of HIPEC with mitomycinc C versus oxaliplatin in 539 patients with colon cancer undergoing a complet...  
  Prada-Villaverde A, Esquivel J, Lowy AM, Markman M, Chua T, Pelz J, Baratti D, Baumgartner JM, Berri R, Bretcha-Boix P, Deraco M, Flores-Ayala G, Glehen O, Gomez-Porti..., J Surg Oncol, 1/1/2014
• The American Society of Peritoneal Surface Malignancies multi-institution evaluation of the peritoneal surface disease severity score in 1013 patients with colorectal ...  
  Esquivel J, Lowy AM, Markman M, Chua T, Pelz J, Baratti D, Baumgartner JM, Berri R, Bretcha-Boix P, Deraco M, Flores-Ayala G, Glehen O, Gomez-Portilla A, Gonzalez-More..., Ann Surg Oncol, 1/1/2014
• A shortened activated partial thromoboplastin time predicts the risk of catheter associated venous thrombosis in cancer patients  
  Senthil M, Chaudhary P, Smith DD, Ventura PE, Frankel PH, Pullarkat V, Trisal V, Thromb Res, 1/1/2014
• Extranodal extension on sentinel lymph node dissection; why should we treat it differently?  
  Choi AH, Surrusco M, Rodriguez S, Bahjri K, Solomon N, Garberoglio C, Lum S, Senthil M, Am Surg, 1/1/2014
• Rate of Re-Excision after Breast-Conserving Surgery for Invasive Lobular Carcinoma  
  ML Wanis, JA Wong, S Rodriguez, JM Wong, B Jabo, A Ashok, SJ Lum, N L Solomon, ME Reeves, CA Garberoglio, M Senthil, American Surgeon, 1/1/2013
• Assessment of clinical benefit and quality of life in patient undergoing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for management of peritone...  
  Senthil M, J Gastrointest Oncol, 1/1/2013
• Allkylation of cysteine 468 in Stat3 defines a novel site for therapeutic development  
  R Buettner, R Corzano, R Rashid, J Lin, M Senthil, M Hedvat, A Schroeder, A Mao, A Herrmann, J Yim, H Lin, YC Yuan, YC Yuan, K Yakushijin, F Yakushijin, N Vaidehi R M..., ACS Chem Biol, 1/1/2011
• Identification of natural compound by cell-based screening that enhances interferon regulatory factor-1 activity and causes tumor suppression  
  J Gao, Y Wang, Q Xing, J Yan, M Senthil, Y Akmal, CM Kowolik, J Kang, DM Lu, M Zhao, Z Lin, CH Cheng, RM Yip, JH Yim, Mol cancer Ther, 1/1/2011
• Liver-directed therapies in the multidisciplinary management of Hepatocellular cancer  
  M Senthil, B Mailey, L leong, V Chung, Y Yen, YJ Chen, H Marx, J Kim, Curr Cancer Ther Rev, 1/1/2010
• IRF-1 transcriptionally upregulates PUMA, which mediates the mitochondrial apoptotic pathway in IRF-1 induced apoptosis in cancer cells  
  J Gao, M Senthil, B Ren, J Yan, Q Xing, J Yu, L Zhang, JH Yim, Cell Death Differ, 1/1/2010
• Transarterial Radioembolization with Yttrium-90 for Regional Management of Hepatocellular Cancer: The Early Results of a Non-Transplant Center  
  A Holt, DW Wagman, M Senthil, S Mckenzie, H Marx, YJ Chen, N Vora, M.D., J Kim, Am Surg, 1/1/2010
• Bicavitary hyperthermic chemotherapy in the management of pseudomyxoma peritoneii with pleural extension  
  M Senthil, LE Harrison, Arch Surg, 1/1/2009
• Trauma- Shock-induced gut injury and the production of biologically active intestinal lymph is abrogated by castration in a large animal model  
  EA Deitch, M Senthil, M Brown, F Caputo, A Watkins, D Anjaria, C Badami, V Pisarenko, D Doucet, Q Lu, E Feketeova, DZ Xu, Shock, 1/1/2008
• Mesenteric Lymph duct ligation improves survival in lethal shock model  
  C Badami, M Senthil, FJ Caputo, BJ Rupani, Doucet D, Pisarenko V, Xu DZ, EA Deitch, Shock, 1/1/2008
• Intravenous injection of Trauma- hemorrhagic shock mesenteric lymph causes lung injury that is dependent upon activation of the inducible nitric oxide synthase pathway  
  M Senthil, M.D., A Watkins, M.D., D Barlos, M.D., DZ Xu M.D., PhD, Q Lu M.D., B Abungu B.Sc., R Feinman PhD, EA. Deitch, M.D., Ann Surg, 1/1/2007
• Trauma hemorrhage-induced gut barrier failure and the production of biologically active intestinal lymph requires pancreatic proteases  
  FJ Caputo, B Rupani, AC Watkins, DBarlos, D Vega, M Senthil, EA. Deitch, Shock, 1/1/2007
• Gut- Lymph Hypothesis of SIRS/MODS: Validating studies in a Porcine Model  
  M Senthil, M.D., M Brown M.S.N., DZ Xu, M.D.,PhD., Q Lu, M.D., E Feketeova M.D., EA. Deitch, M.D., J Trauma, 1/1/2006
• Albumin peptide: a molecular marker for trauma / hemorrhagic-shock in rat mesenteric lymph  
  VL Kaiser, Z Sifri, M Senthil, G S Dikdan, Q Lu, DZ Xu, EA. Deitch, Peptides, 1/1/2005
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Books/Book Chapters

• Acute Care Surgery 
  Chapter: Principles And Practice Of Nutritional Support In Surgical Patients 
  M Senthil, BJ Rupani , JH Jabush, EA DeitchEditors: Britt LD, Trunkey DD, Organ CH, Feliciano DV.Springer Verlag2007

Abstracts/Posters

• Novel STAT3 inhibitor in the Treatment of Breast Cancer
  M Senthil, Q Xing, J Yan, R Buettner, D Horne, R Jove, JH Yim, Sociaty of Surgical Oncology, St. Louis. Indianapoilis, 1/1/2010
• Transarterial Radioembolization with Yttrium-90 for Regional Management of Hepatocellular Cancer: The Early Results of a Non-Transplant Center
  A Holt, DW Wagman, M Senthil, S Mckenzie, H Marx, YJ Chen, N Vora, M.D., J Kim, American College of Surgeons- Southern California Chapter, Santa Barbara, California, 1/1/2010
• Yttrium 90 Selective internal radiation treatment in the management of hepatic malignancies
  M Senthil, B Mailey, N Vora L leong, H Marx, J Kim, ASCO GI, San Francisco, 1/1/2009
• Yttrium 90 Microsphere Selective Internal Radiation Treatment In The Management Of Malignant Liver Tumors
  M Senthil, YJ Chen , N Vora, H Marx, L Wagman, J Kim M.D., Society of Surgical Oncology, Phoenix, 1/1/2009
• Disparities in Gastric Cancer Outcomes among Asian Ethnicities in the United States
  B Mailey, M Senthil, A Artinyan, CL Sun, S Bhatia, J Kim, Society of Surgical Oncology, Phoenix, 1/1/2009
• Trauma-hemorrhagic shock lymph kills multiple cell types and its toxicity is neutralized by albumin
  Vega D, M Senthil, Q Lu, DZ Xu, EA Deitch, Shock Society Conference, Marco Islands, Florida, 1/1/2005
• Pancreatic duct ligation reduces lymph toxicity, PMN activation and gut permeability following trauma / hemorrhagic shock
  BJ Rupani, M Senthil, E Feketeova, Q Lu, EA Deitch, Committee on Trauma Conference, 1/1/2004
• Infusion of Trauma hemorrhagic Shock mesenteric lymph to normal rats recreates shock induced lung injury and decreases RBC deformability
  M Senthil, DZ Xu, S Zaets, T Berezina, EA Deitch, Surgical Infection Society, 24th Annual Meeting, Indianapolis, IN, 1/29/2004
• Mesenteric Lymph duct ligation improves survival in splanchnic artery occlusion shock
  M Senthil, P Ananthakrishanan, BJ Rupani, DZ Xu, EA Deitch, 27th Annual Shock Society Conference, Novascotia, Canada, 1/5./2004
• Trauma Hemorrhagic Shock induced lung injury is mediated via the nitric oxide pathway
  M Senthil , DZ Xu, S Zaets, T Berezina, EA Deitch, UMD – New Jersey medical school, Department of Surgery, Trauma Grand Rounds, Newark, NJ, 1/9./2004
• Intravenous Injection of Trauma-Hemorrhagic Shock Mesenteric Lymph causes lung injury and requires activation of the inducible nitric oxide synthase pathway
  M Senthil , DZ Xu, S Zaets, T Berezina, EA Deitch, 53rd Annual Clinical meeting, New Jersey Chapter, American College of Surgeons, Parsippany, NJ, 1/4./2004
• Intravenous Injection of Trauma-Hemorrhagic Shock Mesenteric Lymph causes lung injury that is dependent upon activation of the inducible nitric oxide synthase pathway
  M Senthil, DZ Xu, Q Lu, T Berezina, B Abungu, S Zaets, R Feinman, EA Deitch, 2nd Joint meeting, Surgical Infection society and Surgical Infection Society- Europe, South Beach Miami, Florida, 1/5./2005
• Pancreatic duct ligation reduces lymph toxicity, PMN activation and gut permeability following trauma / hemorrhagic shock
  BJ Rupani, M Senthil, E Feketeova, Q Lu, EA Deitch, Surgical Infections Society Annual Conference, Miami, Florida, 1/5./2005
• Intravenous Injection of Trauma-Hemorrhagic Shock Mesenteric Lymph causes lung injury that is dependent upon activation of the inducible nitric oxide synthase pathway
  M Senthil, DZ Xu, Q Lu, T Berezina, B Abungu, S Zaets, R Feinman, EA Deitch, Benjamin Rush Jr. Society Annual Conference, 1/20/2005
• Gut- Lymph Hypothesis of SIRS/MODS: Validating studies in a Porcine Model
  M Senthil, M Brown, DZ Xu, Q Lu, E Feketeova, EA.Deitch, American Association for the Surgery of Trauma (AAST) 64th meeting, Atlanta, Georgia, 1/22/2005
• Partial HIF-1 Deficiency Attenuates Ischemia Reperfusion-Mediated Gut and Lung Injury
  AC Watkins, B Abungu, M Senthil, Q Lu, D Barlos, L Prescott, FJ Caputo, BK McCracken, DZ Zu, M Bosch-Marce, GL Semenza, EA Deitch, R Feinmann, 29th Annual Conference on Shock, Broomfield, CO, 1/3./2006
• Molecular staging - Is TNM staging obsolete?
  M Senthil, Grand Rounds, UMDNJ – Department of Surgery, New Jersey Medical School, 1/26/2007
• Shortened Partial thromboplastin predicts teh risk for catheter associated thrombosis in cancer patients
  M Senthil, P Ventura, P Frankel, D Smith, V Pullarkat, V Trisal, Pacific coast Surgical Association, Mauii, Hawaii, 1/13/2010
• Hospital type predicts for the adequacy of lymph node retrieval in colon cancer
  M Senthil, V Trisal, IB Paz, LL Lai, City of Hope GI Multidisciplinary Conference/Pacific coast Surgical Association, Duarte, CA, 2010; Mauii, Hawaii, 2010, 1/13/2010
• A Flavone From Traditional East Asian Natural Extract Inhibits STAT3 and Tumor Growth in Syngeneic Mouse Breast Cancer Model
  M Senthil, Y Akmal, Q Xing, J Yan, JH Yim, San Antonio Breast Cancer Symposium, San Antonio, Texas, 1/8./2010
• Combination of a Natural Compound (Baicalein) and Paclitaxel Resuls in Synergistic Apoptosis in Mouse Breast Cancer Cells
  Y Akmal, M. Senthil, J. Yan, Q. Xing, Y. Wang, G. Somlo, J. Yim, Academic Surgical Congress, Huntington Beach, CA, 1/1./2011
• Extract from Traditional Chinese Herb Scutellaria baicalensis Suppresses Tumors and Inhibits p-AKT in Mice
  Y Akmal, M Senthil, Q Xing, J Yan, Y Wang, J Yim, ASCO Breast Cancer Symposium/Society of Surgical Oncology Annual Cancer Symposium, National Harbor, MD, 2010; San Antonio, TX, 2011, 1/2./2011
• Natural Enhancer of IRF-1 Suppresses Gastric Cancer Tumor Growth in vivo
  Y Akmal, Y Wang, M Senthil, Q Xing, J Yan, J Gao, and J Yim, Society of Surgical Oncology Annual Cancer Symposium, San Antonio, TX, 1/2./2011
• Rate of Re-Excision after Breast-Conserving Surgery for Invasive Lobular Carcinoma
  ML Wanis, JA Wong, S Rodriguez, JM Wong, B Jabo, A Ashok, SJ Lum, N L Solomon, ME Reeves, CA Garberoglio, M Senthil, MD, Southern California Chapter ACS, Santa Barbara, CA, 1/18/2013
• Extranodal extension on sentinel lymph node dissection. Why should we treat it differently?
  AH Choi, MD, M Surrusco, S Rodriguez, K Bahjri, Naveen Solomon, C Garberoglio, S Lum, M Senthil, Southern California Chapter ACS, Santa Barbara, CA, 1/17/2014
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Lectures

• Gaps and Barriers to Research in Global South 
  American College of Surgeons - 10/20/2020
• Management of Colorectal Liver Metastases 
  Chicago, IL - 1/27/2012
• Management of colorectal cancer peritoneal carcinomatosis- Is nihilistic approach justified? 
  Santa Barbara, CA - 1/18/2013
• Cytoreductive Surgery and Hyperthermic intraperitoneal chemotherapy - Anesthetic Management 
  1/20/2013
• Management of Colorectal Peritoneal Carcinomatosis – Current standard of care 
  Loma Linda School of Medicine - 1/3./2013
• Advances in Breast Cancer – Update 
  1/4./2013
• Surgical management of peritoneal carcinomatosis 
  Sri Ramachandra Medical College, Chennai, India - 1/26/2013
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