Maike Sander MD

PubMed

• 10 citations
  Nutrient regulation of the islet epigenome controls adaptive insulin secretion.
  Matthew Wortham, Fenfen Liu, Austin R Harrington, Johanna Y Fleischman, Martina Wallace
  The Journal of Clinical Investigation. 2023-04-17
• 10 citations
  Type 1 diabetes risk genes mediate pancreatic beta cell survival in response to proinflammatory cytokines.
  Paola Benaglio, Han Zhu, Mei-Lin Okino, Jian Yan, Ruth Elgamal
  Cell Genomics. 2022-12-14
• 11 citations
  Systemic LSD1 Inhibition Prevents Aberrant Remodeling of Metabolism in Obesity.
  Bastian Ramms, Dennis P Pollow, Han Zhu, Chelsea Nora, Austin R Harrington
  Diabetes. 2022-12-01

Journal Articles

• PRDM3 attenuates pancreatitis and pancreatic tumorigenesis by regulating inflammatory response.  
  Ye, J.,* Huang, A.,* Wang, H., Zhang, A. M. Y., Huang, X., Lan, Q., Sato, T., Goyama, S., Kurokawa, M., Deng, C., Sander, M., Schaeffer, D. F., Li, W., Kopp, J. L., Xi..., BioRxiv, 2019
• Human stem cell models: lessons for pancreatic development and disease.  
  Gaertner, B., Carrano, A.C., Sander, M., Genes & Development, 2019
• Nutrient regulation of the islet epigenome controls adaptive insulin secretion.  
  Wortham, M., Liu, F.F., Fleischman, J.Y., Wallace, M., Mulas, F., Vinckier, N.K., Harrington, A.R., Cross, B.R., Chiou, J., Patel, N.A., Sui, Y., Jhala, U.S., Shirihai..., BioRxiv, 2019
• LSD1-mediated enhancer silencing enables endocrine cell development through attenuation of retinoic acid signaling.  
  Vinckier, N.K., Patel, N.A., Wang, A., Wang, J., Shih, H.P., Wang, J., Jhala, U.S., Rosenfeld, M.G., Benner, C.W., Sander, M., Nature Communications, 2019
• Beta-cell dysfunction induced by non-cytotoxic concentrations of Interleukin-1β is associated with changes in expression of beta-cell maturity genes and associated his...  
  Ibarra, A.U., Prause, M., Wortham, M., Sui, Y., Thams, P., Sander, M., Christensen G.L., Billestrup, N., Molecular and Cellular Endocrinology, 2019
• Nomenclature for Cellular Plasticity: Are the Terms as Plastic as the Cells Themselves?  
  Mills, J.C., Stanger, B.Z., Sander M., Embo J., 2019
• Single cell chromatin accessibility reveals pancreatic islet cell type- and state-specific regulatory programs of diabetes risk.  
  Chiou, J.,* Zeng, C.,* Cheng, Z., Han, J.Y., Schlichting, M., Huang, S., Wang, J., Sui, Y., Deogaygay, A., Okino, M.L., Qui, Y., Sun, Y., Kudtarkar, P., Fang, R., Prei..., BioRxiv, 2019
• In vivo-mimicking microfluidic perfusion culture of pancreatic islet spheroids.  
  Jun, Y., Lee, J.S., Choi, S., Yang, J.H., Sander, M.*, Chung, S.*, Lee, S.H., Science Advances, 2019
• Differential cell susceptibilities to KrasG12D in the setting of obstructive chronic pancreatitis.  
  Shi, C., Pan, F.P., Kim, J.N., Washington, M.K., Padmanabhan, C., Meyer, C.T., Kopp, J.L., Sander, M., Gannon, M., Beauchamp, R.D., Wright, C.V., Means, A.L., Cellular and Molecular Gastroenterology and Hepatology, 2019
• A network of microRNAs acts to promote cell cycle exit and differentiation of human pancreatic endocrine cells.  
  Jin, W., Mulas, F., Gaertner, B., Sui, Y., Wang, J., Zeng, C., Vinckier, N., Wang, A., Nguyen-Ngoc, K.V., Chiou, J., Kaestner, K.H., Frazer, K., Carrano, A.C., Shih, H..., iScience, 2019
• Pancreatic islet chromatin accessibility and conformation defines distal enhancer networks of type 2 diabetes risk.  
  Greenwald, W.W., Chiou, J., Yan, J., Qiu, Y., Dai, N., Wang, A., Nariai, N., Aylward, A., Han, J., Kadakia, N., Barrufet, L., Okino, M., Drees, F., Vinckier, N., Minic..., Nature Communications, 2019
• N6-methyladenine DNA modification in glioblastoma.  
  Xie, Q., Wu, T., Gimple, R., Li, Z., Prager, B., Wu, Q., Yu, Y., Wang, P., Wang,Y., Gorkin, D., Zhang,C., Dowiak,A., Lin, K., Zeng, C., Sui, Y., Kim, L., Miller, T., J..., Cell, 2018
• Loss of PTEN and activation of Kras synergistically induce formation of intraductal papillary mucinous neoplasia from pancreatic ductal cells in mice.  
  Kopp, J.L., Dubois, C.L., Schaeffer, D.F., Samani, A., Taghizadeh, F., Cowan, R.W., Rhim, A.D., Stiles, B.L., Valasek, M., Sander M., Gastroenterology, 2018
• Cell of origin affects tumor development and phenotype in pancreatic ductal adenocarcinoma.  
  Lee, A., Dubois, C.L., Sarai, K., Zarei, S., Schaeffer, D.F., Sander M., Kopp, J.L., Gut, 2018
• ETV5 regulates ductal morphogenesis with Sox9 and is critical for regeneration from pancreatitis.  
  Das, K., Heeg, S., Pitarresi, J., Reichert, M., Bakir, B., Takano, S., Kopp, J., Feuerstein, A., Hicks, P., Sander, M., Rustgi, A., Developmental Dynamics, 2018
• Epigenetics and epigenomics: Implications for diabetes and obesity.  
  Rosen, E.D., Kaestner, K.H., Natarajan, R., Patti, M.E., Sallari, R., Sander ,M., Susztak, K., Diabetes, 2018
• Pancreatic exocrine tissue architecture and integrity are maintained by E-cadherin during postnatal development.  
  Serrill, J.D., Sander, M., Shih, H.P., Sci Rep, 2018
• Pancreatic islet-autonomous insulin and smoothened-mediated signaling modulate identity changes of glucagon+ α-cells.  
  Cigliola, V., Ghila, L., Thorel, F., van Gurp, L., Baronnier, D., Oropeza, D., Gupta, S., Miyatsuka, T., Kaneto, H., Magnuson, M.A., Osipovich, A.B., Sander, M., Wrigh..., Nature Cell Biology, 2018
• Evaluation of different decellularization protocols on the generation of pancreas-derived hydrogel.  
  Gaetani, R., Aouad, S., Demaddalena, L, Straessle, H., Dzieciatkowska, M., Wortham, M., Bender, H., Nguyen-Ngoc, K., Schmid-Schoenbein, G., George, S., Hughes, C., San..., Tissue Eng Part C, 2018
• Integrated in vivo quantitative proteomics and nutrient tracing reveals age-related metabolic rewiring of pancreatic β-cell function.  
  Wortham, M., Benthuysen, J.R., Wallace, M., Savas, J.N., Mulas, F., Divakaruni, A.S., Liu, F., Albert, V., Taylor, B.L., Sui, Y., Saez, E., Murphy, A.N., Yates, J.R. I..., Cell Reports, 2018
• Interrogating islets in health and disease with single-cell technologies.  
  Carrano, A.C., Mulas, F., Zeng, C., Sander, M., Molecular Metabolism, 2017
• Pseudotemporal ordering of single cells reveals metabolic control of postnatal beta-cell proliferation.  
  Zeng, C., Mulas, F., Sui, Y., Guan, T., Miller, N., Tan, Y., Liu, F., Jin, W., Carrano, A.C., Huising, M.O., Shirihai, O.S., Yeo, G.W., Sander, M., Cell Metabolism, 2017
• Ldb1 maintains the terminally differentiated state of pancreatic β-cells.  
  Ediger, B., Hee-Wong, L., Juliana, C., Groff, D., Williams, L., Dominguez, G., Taylor, B.L., Walp, E., Kameswaran, V., Yang, J., Liu, C., Hunter, C., Kaestner, K.H., N..., Journal of Clinical Investigation, 2017
• Advances in β-cell replacement and regeneration strategies for treating diabetes.  
  Benthuysen, J.R., Carrano, A.C., Sander, M., Journal of Clinical Investigation, 2016
• ECM signaling regulates collective cellular dynamics to control pancreas branching morphogenesis.  
  Shih, H.P., Panlasigui, D., Cirulli, V., Sander, M., Cell Reports, 2016
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Books/Book Chapters

• Cellular and Molecular Biology of the Renin-Angiotensin System 
  Chapter: Renin Gene Expression and Hypertension in Transgenic Animals 
  Page 59 - 93Bader, M., Lee, M., Zhao, Y., Böhm, M., Bachmann, J., Sander, M., Djavidani, B., Bachmann, S., Zimmermann, F., Wilbertz, J., Zeh, K., Wagner, J., Peters, J., Ganten, D.CRC Press1993