MaimonHubbiMD

PubMed

• Detecting Hypoxia-Inducible Factor Levels and Activity.
  Hubbi, M.> ;Methods in Molecular Biology. 2024 Jan 1
• 9 citations
  Lactate-dependent chaperone-mediated autophagy induces oscillatory HIF-1α activity promoting proliferation of hypoxic cells.
  Kshitiz, Junaid Afzal, Yasir Suhail, Maimon E Hubbi, Archer Hamidzadeh, Ruchi Goyal, Yamin Liu, Peng Sun, Stefania Nicoli, Chi V Dang, Andre Levchenko, Chang, H.> ;Cell Systems. 2022 Dec 21
• 2 citations
  Bcl-xL Enforces a Slow-Cycling State Necessary for Survival in the Nutrient-Deprived Microenvironment of Pancreatic Cancer.
  Sela, Y., Li, J., Maheswaran, S., Norgard, R., Yuan, S., Hubbi, M., Doepner, M., Xu, J., Ho, E., Mesaros, C., Sheehan, C., Croley, G., Muir, A., Blair, I., Shalem, O.,...> ;Cancer Research. 2022 May 16
• 1 citations
  Isolated Erythrocytosis Associated With 3 Novel Missense Mutations in the EGLN1 Gene.
  Joseph A. Moore, Maimon E. Hubbi, Chenliang Wang, Yingfei Wang, Weibo Luo, Sandra L. Hofmann, Siayareh Rambally> ;Journal of Investigative Medicine High Impact Case Reports. 2020 Aug 5
• 63 citations
  A calcineurin–Hoxb13 axis regulates growth mode of mammalian cardiomyocytes
  , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , > ;Nature. 2020 Apr 22
• 176 citations
  Regulation of cell proliferation by hypoxia-inducible factors
  Maimon E. Hubbi, Gregg L. Semenza> ;American Journal of Physiology. Cell Physiology. 2015 Dec 15
• 28 citations
  Huntington’s disease: Neural dysfunction linked to inositol polyphosphate multikinase
  Ishrat Ahmed, Juan I. Sbodio, Maged M. Harraz, Richa Tyagi, Jonathan C. Grima, Maimon E. Hubbi, Risheng Xu, Seyun Kim, Bindu D. Paul, Solomon H. Snyder> ;Proceedings of the National Academy of Sciences of the United States of America. 2015 Aug 4
• 23 citations
  An essential role for chaperone-mediated autophagy in cell cycle progression.
  Maimon E. Hubbi, Gregg L. Semenza> ;Autophagy. 2015 May 6
• 7 citations
  Control of the interface between heterotypic cell populations reveals the mechanism of intercellular transfer of signaling proteins.
  , , , , , , , , , , , , , , , > ;Integrative Biology. 2015 Mar 9
• 80 citations
  Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression.
  Maimon E. Hubbi, Daniele M. Gilkes, Hongxia Hu, Kshitiz, Ishrat Ahmed, Gregg L. Semenza> ;Proceedings of the National Academy of Sciences of the United States of America. 2014 Aug 12
• 148 citations
  Hypoxia-inducible factors mediate coordinated RhoA-ROCK1 expression and signaling in breast cancer cells
  Daniele M. Gilkes, Lisha Xiang, Sun Joo Lee, Maimon E. Hubbi, Denis Wirtz, Gregg L. Semenza> ;Proceedings of the National Academy of Sciences of the United States of America. 2014 Jan 21
• 103 citations
  Sirtuin-7 inhibits the activity of hypoxia-inducible factors.
  Maimon E. Hubbi, Hongxia Hu, Kshitiz, Daniele M. Gilkes, Gregg L. Semenza> ;The Journal of Biological Chemistry. 2013 Jul 19
• 209 citations
  Collagen Prolyl Hydroxylases are Essential for Breast Cancer Metastasis
  Daniele M. Gilkes, Pallavi Chaturvedi, Saumendra Bajpai, Carmen Chak-Lui Wong, Hong Wei, Maimon E. Hubbi, Denis Wirtz, Gregg L. Semenza> ;Cancer Research. 2013 Jun 1
• 187 citations
  Procollagen Lysyl Hydroxylase 2 Is Essential for Hypoxia-Induced Breast Cancer Metastasis
  Daniele M. Gilkes, Saumendra Bajpai, Carmen Chak-Lui Wong, Maimon E. Hubbi, Denis Wirtz, Gregg L. Semenza> ;Molecular Cancer Research. 2013 May 1
• 163 citations
  Chaperone-mediated Autophagy Targets Hypoxia-inducible Factor-1α (HIF-1α) for Lysosomal Degradation
  Maimon E. Hubbi, Hongxia Hu, Kshitiz, Ishrat Ahmed, Andre Levchenko, Gregg L. Semenza> ;The Journal of Biological Chemistry. 2013 Apr 12
• 86 citations
  A Nontranscriptional Role for HIF-1α as a Direct Inhibitor of DNA Replication
  Maimon E. Hubbi, Kshitiz, Daniele M. Gilkes, Sergio Rey, Carmen Chak-Lui Wong, Weibo Luo, Deok Ho Kim, Chi V. Dang, Andre Levchenko, Gregg L. Semenza> ;Science Signaling. 2013 Feb 12
• 51 citations
  Matrix Rigidity Controls Endothelial Differentiation and Morphogenesis of Cardiac Precursors
  Maimon E. Hubbi, Eun Hyun Ahn, John E. Downey, Junaid Afzal, Deok Ho Kim, Sergio Rey, Connie Y. Chang, Arnab Kundu, Gregg L. Semenza, Roselle Abraham, Andre Levchenko,...> ;Science Signaling. 2012 Jun 5
• 43 citations
  Four-and-a-Half LIM Domain Proteins Inhibit Transactivation by Hypoxia-inducible Factor 1
  Maimon E. Hubbi, Daniele M. Gilkes, Jin H. Baek, Gregg L. Semenza> ;The Journal of Biological Chemistry. 2012 Feb 24
• 171 citations
  Inhibitors of hypoxia-inducible factor 1 block breast cancer metastatic niche formation and lung metastasis.
  Carmen Chak-Lui Wong, Huafeng Zhang, Daniele M. Gilkes, Jasper Chen, Hong Wei, Maimon E. Hubbi, Gregg L. Semenza> ;Journal of Molecular Medicine. 2012 Jan 10
• 69 citations
  MCM Proteins Are Negative Regulators of Hypoxia-Inducible Factor 1
  Maimon E. Hubbi, Weibo Luo, Jin H. Baek, Gregg L. Semenza> ;Molecular Cell. 2011 Jun 10
• 119 citations
  Calcineurin Promotes Hypoxia-inducible Factor 1α Expression by Dephosphorylating RACK1 and Blocking RACK1 Dimerization
  Maimon E. Hubbi, Fan Pan, Karin R. McDonald, Malini Mansharamani, Robert N. Cole, Jun O. Liu, Gregg L. Semenza> ;The Journal of Biological Chemistry. 2007 Dec 21
• 52 citations
  Spermidine/Spermine-N1-Acetyltransferase 2 Is an Essential Component of the Ubiquitin Ligase Complex That Regulates Hypoxia-inducible Factor 1α
  Jin Hyen Baek, Ye V. Liu, Karin R. McDonald, Maimon E. Hubbi, Hweejo Byun, Gregg L. Semenza> ;The Journal of Biological Chemistry. 2007 Aug 10
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