MalcolmKamauJohnsonMD

PubMed

• 8 citations
  Bronchial mucosal inflammation and illness severity in response to experimental rhinovirus infection in COPD
  Jie Zhu, Patrick Mallia, Joseph Footitt, Yusheng Qiu, Simon D. Message, Tatiana Kebadze, Julia Aniscenko, Peter J. Barnes, Ian M. Adcock, Onn Min Kon, Malcolm Johnson,...> ;The Journal of Allergy and Clinical Immunology. 2020 Oct 1
• 2 citations
  Intracellular interactions of umeclidinium and vilanterol in human airway smooth muscle.
  Nooreen Shaikh, Malcolm Johnson, David A. Hall, Kian Fan Chung, John H. Riley, Sally Worsley, Pankaj K. Bhavsar> ;International Journal of Chronic Obstructive Pulmonary Disease. 2017 Jun 30
• 10 citations
  Responsiveness of blood and sputum inflammatory cells in Japanese COPD patients, non-COPD smoking controls, and non-COPD nonsmoking controls.
  Tomotaka Kawayama, Takashi Kinoshita, Kazuko Matsunaga, Akihiro Kobayashi, Tomoyuki Hayamizu, Malcolm Johnson, Tomoaki Hoshino> ;International Journal of Chronic Obstructive Pulmonary Disease. 2016 Feb 10
• 19 citations
  The long-acting β2 -adrenoceptor agonist, indacaterol, enhances glucocorticoid receptor-mediated transcription in human airway epithelial cells in a gene- and agonist-...
  Taruna Joshi, Marvin Johnson, Robert Newton, Mark A. Giembycz> ;British Journal of Pharmacology. 2015 May 1
• 9 citations
  Anti-inflammatory effects of salmeterol/fluticasone propionate 50/250 mcg combination therapy in Japanese patients with chronic obstructive pulmonary disease
  Kazuhisa Asai, Akihiro Kobayashi, Yukio Makihara, Malcolm Johnson> ;International Journal of Chronic Obstructive Pulmonary Disease. 2015 Apr 17
• 24 citations
  An analysis of glucocorticoid receptor-mediated gene expression in BEAS-2B human airway epithelial cells identifies distinct, ligand-directed, transcription profiles w...
  Taruna Joshi, Marvin Johnson, Robert Newton, Mark A. Giembycz> ;British Journal of Pharmacology. 2015 Mar 1
• 35 citations
  Reversal of corticosteroid insensitivity by p38 MAPK inhibition in peripheral blood mononuclear cells from COPD.
  Nadia Khorasani, Josephine Baker, Malcolm Johnson, Kian Fan Chung, Pankaj K. Bhavsar> ;International Journal of Chronic Obstructive Pulmonary Disease. 2015 Feb 4
• 17 citations
  Airway inflammation in Japanese COPD patients compared with smoking and nonsmoking controls
  Nobuhisa Ishikawa, Noboru Hattori, Nobuoki Kohno, Akihiro Kobayashi, Tomoyuki Hayamizu, Malcolm Johnson> ;International Journal of Chronic Obstructive Pulmonary Disease. 2015 Jan 23
• 15 citations
  Lymphocyte subsets in experimental rhinovirus infection in chronic obstructive pulmonary disease
  Patrick Mallia, Simon D. Message, Marco Contoli, Katrina Gray, Aurica G. Telcian, Vasile Laza-Stanca, Alberto Papi, Luminita A. Stanciu, Sarah L. Elkin, Onn Min Kon, M...> ;Respiratory Medicine. 2014 Jan 1
• 37 citations
  Induction of regulator of G-protein signaling 2 expression by long-acting β2-adrenoceptor agonists and glucocorticoids in human airway epithelial cells.
  Neil S. Holden, Tresa George, Christopher F. Rider, Ambika Chandrasekhar, Suharsh Shah, Manminder Kaur, Malcolm Johnson, David P. Siderovski, Richard Leigh, Mark A. Gi...> ;The Journal of Pharmacology and Experimental Therapeutics. 2014 Jan 1
• 20 citations
  Neutrophil adhesion molecules in experimental rhinovirus infection in COPD
  Patrick Mallia, Simon D. Message, Marco Contoli, Katrina Gray, Aurica G. Telcian, Vasile Laza-Stanca, Alberto Papi, Luminita A. Stanciu, Sarah L. Elkin, Onn Min Kon, M...> ;Respiratory Research. 2013 Jul 8
• 187 citations
  Rhinovirus Infection Induces Degradation of Antimicrobial Peptides and Secondary Bacterial Infection in Chronic Obstructive Pulmonary Disease
  Patrick Mallia, Joseph Footitt, Rosa Sotero, Annette Jepson, Marco Contoli, Maria-Belen Trujillo-Torralbo, Tatiana Kebadze, Julia Aniscenko, Gregory Oleszkiewicz, Katr...> ;American Journal of Respiratory and Critical Care Medicine. 2012 Dec 1
• 61 citations
  Beta defensin-2 is reduced in central but not in distal airways of smoker COPD patients.
  Elisabetta Pace, Maria Ferraro, Marta I. Minervini, Patrizio Vitulo, Loredana Pipitone, Giuseppina Chiappara, Liboria Siena, Angela Marina Montalbano, Malcolm Johnson,...> ;Plos One. 2012 Mar 16
• 71 citations
  β2-Adrenoceptor agonist-induced RGS2 expression is a genomic mechanism of bronchoprotection that is enhanced by glucocorticoids
  Neil S. Holden, Matthew J. Bell, Christopher F. Rider, Elizabeth M. King, David D. Gaunt, Richard Leigh, Malcolm Johnson, David P. Siderovski, Scott P. Heximer, Mark A...> ;Proceedings of the National Academy of Sciences of the United States of America. 2011 Dec 6
• 48 citations
  Long-acting fluticasone furoate has a superior pharmacological profile to fluticasone propionate in human respiratory cells☆
  Christos Rossios, Yasuo To, Masako To, Misako Ito, Peter J. Barnes, Ian M. Adcock, Malcolm Johnson, Kazuhiro Ito> ;European Journal of Pharmacology. 2011 Nov 16
• 283 citations
  Experimental Rhinovirus Infection as a Human Model of Chronic Obstructive Pulmonary Disease Exacerbation
  Patrick Mallia, Simon D. Message, V Gielen, Marco Contoli, Katrina Gray, Tatiana Kebadze, Julia Aniscenko, Vasile Laza-Stanca, Michael R. Edwards, Louise Slater, Alber...> ;American Journal of Respiratory and Critical Care Medicine. 2011 Mar 15
• 43 citations
  TLR4 upregulation underpins airway neutrophilia in smokers with chronic obstructive pulmonary disease and acute respiratory failure
  Elisabetta Pace, Antonino Giarratano, Maria Ferraro, Andreina Bruno, Liboria Siena, Salvatore Mangione, Malcolm Johnson, Mark Gjomarkaj> ;Human Immunology. 2011 Jan 1
• 12 citations
  Cilomilast counteracts the effects of cigarette smoke in airway epithelial cells
  Elisabetta Pace, Maria Ferraro, Carina Gabriela Uasuf, Antonino Giarratano, Stefania La Grutta, Giuseppe Liotta, Malcolm Johnson, Mark Gjomarkaj> ;Cellular Immunology. 2011 Jan 1
• 82 citations
  Effect of p38 MAPK inhibition on corticosteroid suppression of cytokine release in severe asthma
  Pank Bhavsar, Nadia Khorasani, Mark Hew, Malcolm Johnson, Kian Fan Chung> ;The European Respiratory Journal. 2010 Apr 1
• 10 citations
  Parasternal Muscle Activity Decreases in Severe COPD With Salmeterol-Fluticasone Propionate
  Paul A. Easton, Harvey G. Hawes, Christopher J. Doig, Malcolm Johnson, Masanori Yokoba, Eric Wilde> ;Chest. 2010 Mar 1
• 3 citations
  Long acting β2-agonist and corticosteroid restore airway glandular cell function altered by bacterial supernatant
  Jean-Marie Zahm, Franck Delavoie, Férial Toumi, Béatrice Nawrocki-Raby, C. Kileztky, Jean Michel, Gérard Balossier, Malcolm Johnson, Christelle Coraux, Philippe Birembaut> ;Respiratory Research. 2010 Jan 20
• 40 citations
  Salmeterol with fluticasone enhances the suppression of IL-8 release and increases the translocation of glucocorticoid receptor by human neutrophils stimulated with ci...
  Esmaeil Mortaz, Mehdi Vaezi Rad, Malcolm Johnson, Danielle A.E. Raats, Frans P. Nijkamp, Gert Folkerts> ;Journal of Molecular Medicine. 2008 Jul 4
• 154 citations
  Cigarette smoke increases Toll-like receptor 4 and modifies lipopolysaccharide-mediated responses in airway epithelial cells.
  Elisabetta Pace, Maria Ferraro, Liboria Siena, Mario Melis, Angela Marina Montalbano, Malcolm Johnson, Maria R. Bonsignore, Giovanni Bonsignore, Mark Gjomarkaj> ;Immunology. 2008 Jul 1
• 17 citations
  Fluticasone, but not salmeterol, reduces cigarette smoke-induced production of interleukin-8 in human airway smooth muscle.
  Ute Oltmanns, Matt Walters, Maria B. Sukkar, Sherry Xie, Razao Issa, Jane A. Mitchell, Malcolm Johnson, Kian Fan Chung> ;Pulmonary Pharmacology & Therapeutics. 2008 Apr 1
• 18 citations
  Combination of fluticasone propionate and salmeterol potentiates the suppression of cigarette smoke-induced IL-8 production by macrophages.
  Hadi Sarir, Esmaeil Mortaz, Khalil Karimi, Malcolm Johnson, Frans P. Nijkamp, Gert Folkerts> ;European Journal of Pharmacology. 2007 Sep 24
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