
Manoj Pillai MD
Hematologic Oncology
Associate Professor of Medicine, Yale University School of Medicine
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12605 E 16th AveAurora, CO 80045
Phone+1 720-848-0000
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Education & Training
University of WashingtonFellowship, Hematology and Medical Oncology, 2002 - 2005
Baylor College of MedicineResidency, Internal Medicine, 1999 - 2002
All India Institute of Medical SciencesClass of 1998
Certifications & Licensure
CT State Medical License 2013 - 2026
CO State Medical License 2008 - 2015
American Board of Internal Medicine Medical Oncology
Awards, Honors, & Recognition
- CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory - Core EMR, Epic Systems Corporation, 2013
- CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013
Publications & Presentations
PubMed
- METTL3 promotes cell-cycle progression via activation of transcriptional elongation.Azime Akçaöz-Alasar, Yanhua Wang, Hang Li, Denis Ostapenko, Carlos A Ramírez Parrado
Molecular Cell. 2026-08-20 - 25 citationsTranscription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape.Prajwal C Boddu, Abhishek K Gupta, Rahul Roy, Bárbara De La Peña Avalos, Anne Olazabal-Herrero
Molecular Cell. 2024-04-18 - 12 citationsPD-1H/VISTA mediates immune evasion in acute myeloid leukemia.Tae Kon Kim, Xue Han, Qianni Hu, Esten N Vandsemb, Carly M Fielder
The Journal of Clinical Investigation. 2024-02-01
Abstracts/Posters
- Immune Checkpoint Inhibitor Therapy for Acute Myeloid Leukemia and Higher-Risk Myelodysplastic Syndromes: A Single-Center ExperienceManoj M Pillai, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
- U2AF1 Driver Mutations in Hematopoietic Disorders Alter but Do Not Abrogate RNA Binding and Enlighten Structural Dependencies of the U2AF-RNA ComplexManoj M Pillai, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
- SF3B1 Mutations Induce Oncogenic IRAK4 Isoforms and Activate Targetable Innate Immune Pathways in MDS and AMLManoj M Pillai, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
Grant Support
- Mechanisms of transcriptional dysregulation in SF3B1 mutant MDSYALE UNIVERSITY2026–2027
- Altered RNA fates due to an MDS driver mutation in SF3B1YALE UNIVERSITY2024–2027
- Biology of terminal R-loops in splicing factor mutant cancersYALE UNIVERSITY2023–2025
- Biology of terminal R-loops in splicing factor mutant cancersYALE UNIVERSITY2023–2025
External Links
- Pillai Labhttp://medicine.yale.edu/lab/pillai/index.aspx
- Manoj Pillaihttp://medicine.yale.edu/lab/pillai/people//manoj_pillai.profile?source=news
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